All Stories

  1. The frequency and pathogenicity of BRCA1 and BRCA2 variants in the general Japanese population
  2. Long Noncoding RNA RP11-278A23.1, a Potential Modulator of p53 Tumor Suppression, Contributes to Colorectal Cancer Progression
  3. The frequency and pathogenicity of BRCA1 and BRCA2 variants in the general Japanese population.
  4. MYEOV overexpression induced by demethylation of its promoter contributes to pancreatic cancer progression via activation of the folate cycle/c-Myc/mTORC1 pathway
  5. Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
  6. Predictive value of an exosomal microRNA-based signature for tumor immunity in cervical cancer patients treated with chemoradiotherapy
  7. Dual inhibition of BCL2L1 and MCL1 is highly effective against RET fusion-positive or MET exon 14 skipping mutation-positive lung adenocarcinoma cells
  8. Impact of sensitive circulating tumor DNA monitoring on CT scan intervals during postoperative colorectal cancer surveillance
  9. Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma
  10. Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations
  11. Individualized circulating tumor DNA monitoring in head and neck squamous cell carcinoma
  12. Estimation of the true infection rate and infection fatality rate of coronavirus disease 2019 in each country
  13. BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma
  14. Functional Depletion of HSP72 by siRNA and Quercetin Enhances Vorinostat-Induced Apoptosis in an HSP72-Overexpressing Cutaneous T-Cell Lymphoma Cell Line, Hut78
  15. DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes
  16. Early dynamics of circulating tumor DNA predict chemotherapy responses for patients with esophageal cancer
  17. Dead or alive? Pitfall of survival analysis with TCGA datasets
  18. Genetic analyses of a secondary poroma and trichoblastoma in a HRAS‐mutated sebaceous nevus
  19. ALK-positive atypical Spitz tumour with conspicuous rosette-like structures
  20. Early dynamics of circulating tumor DNA predict chemotherapy responses for patients with esophageal cancer
  21. Correlation between PCR Examination Rate among the Population and the Containment of Pandemic of COVID-19
  22. Interactive Web-based Graphs of Coronavirus Disease 2019 Cases and Deaths per Population by Country
  23. Genetic analyses of mosaic neurofibromatosis type 1 with giant café‐au‐lait macule, plexiform neurofibroma and multiple melanocytic nevi
  24. Renal angiomyolipoma (AML) harboring a missense mutation of TSC2 with copy-neutral loss of heterozygosity (CN-LOH)
  25. p53-induced ARVCF modulates the splicing landscape and supports the tumor suppressive function of p53
  26. Corrigendum to “Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer”
  27. Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer
  28. High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme
  29. Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma
  30. Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1
  31. HSP72 functionally inhibits the anti-neoplastic effects of HDAC inhibitors
  32. Identification and characterization of a metastatic suppressor BRMS1L as a target gene of p53
  33. Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing
  34. Fledglings in p53 signaling network
  35. p53 mediates the suppression of cancer cell invasion by inducing LIMA1/EPLIN
  36. Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function
  37. Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target
  38. CRKL oncogene is downregulated by p53 through miR‐200s
  39. Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model
  40. Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells
  41. Mesenchymal Stem Cells Cancel Azoxymethane-Induced Tumor Initiation
  42. Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites
  43. Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors
  44. Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness
  45. AKR1B10, a Transcriptional Target of p53, Is Downregulated in Colorectal Cancers Associated with Poor Prognosis
  46. CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion
  47. A novel approach to cancer treatment using structural hybrids of the p53 gene family
  48. CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation
  49. p53 Negatively Regulates the Hepatoma Growth Factor HDGF
  50. A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth
  51. A Single Recombinant Adenovirus Expressing p53 and p21-targeting Artificial microRNAs Efficiently Induces Apoptosis in Human Cancer Cells
  52. CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-κB
  53. p53 Family Members Regulate the Expression of the Apolipoprotein D Gene
  54. Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models
  55. Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors
  56. Antitumor effect of adenovirus-mediated p53 family gene transfer on osteosarcoma cell lines
  57. Involvement of Splicing Factor-1 in β-Catenin/T-Cell Factor-4-Mediated Gene Transactivation and Pre-mRNA Splicing
  58. Ku70 and Poly(ADP-Ribose) Polymerase-1 Competitively Regulate β-Catenin and T-Cell Factor-4–Mediated Gene Transactivation: Possible Linkage of DNA Damage Recognition and Wnt Signaling
  59. E-Cadherin Regulates the Association between β-Catenin and Actinin-4
  60. β-Catenin Interacts With the FUS Proto-oncogene Product and Regulates Pre-mRNA Splicing
  61. Poly(ADP-Ribose) Polymerase-1 Is a Component of the Oncogenic T-Cell Factor-4/β-Catenin Complex
  62. Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic β-catenin protein
  63. Actinin-4 increases cell motility and promotes lymph node metastasis of colorectal cancer
  64. Alternative splice variant of actinin-4 in small cell lung cancer
  65. Overexpression of BAD preferentially augments anoikis
  66. A Case of aseptic osteomyelitis with heel ulcer improved by steroid application.
  67. A Case of Thymoma and Hypogammaglobulinemia(Good's syndrome) with Lichen planus.