Subject: ChemistryPrimary location: United Kingdom
Published in:Chemical CommunicationsPublication date:2012-01-01
How to make a thioester equivalent by Fmoc chemistry for use in chemical ligation. The sulfonamide linker attached to a solid phase was the first F...
Published in:Chemical SciencePublication date:2014-01-01
with the evolution of ligation reactions coupling unprotected peptides together to make proteins, there has been a search for Fmoc compatible metho...
Published in:Chemical CommunicationsPublication date:2014-01-01
poor solubility is the major factor behind many of the problems met in peptide chemistry. From synthesis to handling and purification. The alkylati...
Published in:Chemical CommunicationsPublication date:2008-01-01
One of the holy grails of ligation is a three piece ligation without the need for further protecting groups. Here is one approach to that with an a...
Published in:Journal of the Chemical Society Perkin Transactions 1Publication date:1992-01-01
Published in:Journal of the Chemical Society Perkin Transactions 1Publication date:1996-01-01
Published in:NaturePublication date:2007-06-24
Published in:BiopolymersPublication date:2010-06-03
Published in:Journal of the American Chemical SocietyPublication date:2002-05-01
Published in:Organic LettersPublication date:2000-01-01
Published in:Journal of Peptide SciencePublication date:2016-01-01
Advances in Fmoc Solid-Phase Peptide Synthesis
a bench chemists guide to developments in Fmoc solid phase peptide chemistry. Although extremely powerful Fmoc solid phase synthesis has limitation...
Published in:Tetrahedron LettersPublication date:1997-12-01
Published in:Bioorganic & Medicinal ChemistryPublication date:2004-05-01
Published in:Journal of Peptide SciencePublication date:2016-04-18
A Backbone Amide Protecting Group
peptide insolubility is structural in origin and is not due to hydrophobicity and yet most approaches to dealing with insolubility do so by adding ...
Published in:NaturePublication date:2007-04-26
Published in:Molecular CellPublication date:2015-03-01
Published in:Angewandte ChemiePublication date:2016-09-01
Want to use Boc chemistry to make peptides but afraid of HF? This is an easy, cheap alternative. Boc SPPS can make some very high quality peptides...