All Stories

  1. The diverse evolutionary histories of domesticated metaviral capsid genes in mammals
  2. Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins
  3. Expansion and loss of sperm nuclear basic protein genes in Drosophila correspond with genetic conflicts between sex chromosomes
  4. Driving lessons: a brief (personal) history of centromere drive
  5. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species
  6. Genetic conflicts between sex chromosomes drive expansion and loss of sperm nuclear basic protein genes in Drosophila
  7. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species
  8. Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline
  9. The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
  10. Novel classes and evolutionary turnover of histone H2B variants in the mammalian germline
  11. An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development
  12. Gametic specialization of centromeric histone paralogs in Drosophila virilis
  13. Putting the brakes on centromere drive in Mimulus
  14. A balancing act between primate lentiviruses and their receptor
  15. Biparental contributions of the H2A.B histone variant control embryonic development in mice
  16. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
  17. A natural variant of the essential host gene MMS21 restricts the parasitic 2-micron plasmid in Saccharomyces cerevisiae
  18. AcrIIA22 is a novel anti-CRISPR that impairs SpyCas9 activity by relieving DNA torsion of target plasmids
  19. A rapidly evolving actin mediates fertility and developmental tradeoffs in Drosophila
  20. Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races
  21. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
  22. Natural variation in an essential host gene contributes to parasitic plasmid resistance in Saccharomyces cerevisiae
  23. Ancient Coretention of Paralogs of Cid Centromeric Histones and Cal1 Chaperones in Mosquito Species
  24. Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes
  25. Hybridization promotes asexual reproduction in Caenorhabditis nematodes
  26. A Burst of Genetic Innovation in Drosophila Actin-Related Proteins for Testis-Specific Function
  27. Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins
  28. Dynamic evolution of de novo DNA methyltransferases in rodent and primate genomes
  29. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
  30. A burst of genetic innovation in actin-related proteins (Arps) for testis-specific function in a Drosophila lineage
  31. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
  32. Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization
  33. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
  34. Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff
  35. Gametic specialization of centromeric histone paralogs in Drosophila virilis
  36. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA
  37. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
  38. Culture shock
  39. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals
  40. The gene drive bubble: New realities
  41. wtf genes are prolific dual poison-antidote meiotic drivers
  42. Recurrent Gene Duplication Leads to Diverse Repertoires of Centromeric Histones in Drosophila Species
  43. Genetic conflicts: the usual suspects and beyond
  44. The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila ...
  45. Recurrent gene duplication leads to diverse repertoires of centromeric histones in Drosophila species
  46. A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility inDrosophila melanogaster
  47. Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
  48. Evolution of a transcriptional regulator from a transmembrane nucleoporin
  49. Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution
  50. Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline
  51. Recurrent gene duplication diversifies genome defense repertoire in Drosophila
  52. Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?
  53. An essential cell cycle regulation gene causes hybrid inviability in Drosophila
  54. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction
  55. Chromosome Segregation: Human Female Meiosis Breaks All the Rules
  56. LINE-1 Retroelements Get ZAPped!
  57. Mitotic fidelity requires transgenerational action of a testis-restricted HP1
  58. R2d2 and Hyperdrive Mechanisms (in Mouse Meiosis)
  59. Speciation via Autoimmunity: A Dangerous Mix
  60. Transferred interbacterial antagonism genes augment eukaryotic innate immune function
  61. Genetic Conflicts: Stronger Centromeres Win Tug-of-War in Female Meiosis
  62. Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects
  63. How a Virus Blocks a Cellular Emergency Access Lane to the Nucleus, STAT!
  64. Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast
  65. Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts
  66. Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
  67. Mobile DNA: an evolving field
  68. Mobile genetic elements and genome evolution 2014
  69. An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family
  70. Host gene evolution traces the evolutionary history of ancient primate lentiviruses
  71. An evolutionary perspective on the broad antiviral specificity of MxA
  72. A rapidly evolving genomic toolkit forDrosophilaheterochromatin
  73. Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes
  74. Stepwise Evolution of Essential Centromere Function in a Drosophila Neogene
  75. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes
  76. Rules of Engagement: Molecular Insights from Host-Virus Arms Races
  77. Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
  78. Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA
  79. Poxviruses Deploy Genomic Accordions to Adapt Rapidly against Host Antiviral Defenses
  80. Rapid evolution of centromeres and centromeric/kinetochore proteins
  81. The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses
  82. Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family
  83. A unified phylogeny-based nomenclature for histone variants
  84. Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
  85. The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx
  86. Retroviruses push the envelope for mammalian placentation
  87. Birth, Death, and Replacement of Karyopherins in Drosophila
  88. Learning to Protect Your Genome on the Fly
  89. Adaptive Evolution of Centromeric Proteins
  90. Paleovirology—ghosts and gifts of viruses past
  91. The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection
  92. Absence of Positive Selection on Centromeric Histones in Tetrahymena Suggests Unsuppressed Centromere-Drive in Lineages Lacking Male Meiosis
  93. Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses
  94. Paleovirology—Modern Consequences of Ancient Viruses
  95. Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces
  96. Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa
  97. Multiple Roles for Heterochromatin Protein 1 Genes inDrosophila
  98. Diamonds and rust: how transposable elements influence mammalian genomes
  99. Altered Heterochromatin Binding by a Hybrid Sterility Protein in Drosophila Sibling Species
  100. The evolutionary conundrum of pathogen mimicry
  101. Major Evolutionary Transitions in Centromere Complexity
  102. Evolution of TRIM antiviral genes in primate genomes
  103. A Surrogate Approach to Study the Evolution of Noncoding DNA Elements That Organize Eukaryotic Genomes
  104. The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions
  105. An expanded clade of rodent Trim5 genes
  106. The Centromere-Drive Hypothesis: A Simple Basis for Centromere Complexity
  107. Protein kinase R reveals an evolutionary model for defeating viral mimicry
  108. Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins
  109. Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution
  110. The Evolution of Centromeric DNA Sequences
  111. Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein
  112. Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals
  113. Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila
  114. Restriction of an Extinct Retrovirus by the Human TRIM5  Antiviral Protein
  115. Molecular Evolution of Drosophilacdc6, an Essential DNA Replication-Licensing Gene, Suggests an Adaptive Choice of Replication Origins
  116. Genes get diabolical
  117. Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis
  118. A hitchhiker's guide to survival finally makes CENs
  119. Genetic conflicts during meiosis and the evolutionary origins of centromere complexity: Figure 1
  120. Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H
  121. High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans
  122. The CNA1 Histone of the Ciliate Tetrahymena thermophila Is Essential for Chromosome Segregation in the Germline Micronucleus
  123. finds centromeres in the driver's seat
  124. Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain
  125. Ribonuclease H evolution in retrotransposable elements
  126. Positive Selection of Iris, a Retroviral Envelope–Derived Host Gene in Drosophila melanogaster
  127. Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila
  128. Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G
  129. Phylogenomics of the nucleosome
  130. Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9
  131. Conflict begets complexity: the evolution of centromeres
  132. Centromeres: Selfish drivers
  133. Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone
  134. Origins and Evolution of Retrotransposons
  135. Speciation and Centromere Evolution
  136. The Centromere Paradox: Stable Inheritance with Rapidly Evolving DNA
  137. Phylogenetic Analysis of Ribonuclease H Domains Suggests a Late, Chimeric Origin of LTR Retrotransposable Elements and Retroviruses
  138. Ten-Kilodalton Domain in Ty3 Gag3-Pol3p between PR and RT Is Dispensable for Ty3 Transposition
  139. Dual recognition–incision enzymes might be involved in mismatch repair and meiosis
  140. Poised for Contagion: Evolutionary Origins of the Infectious Abilities of Invertebrate Retroviruses
  141. Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans
  142. A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli
  143. Are retrotransposons long-term hitchhikers?
  144. Evolutionary specialization of the nuclear targeting apparatus