All Stories

  1. Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies
  2. HDAC6-ubiquitin interaction controls the duration of HSF1 activation after heat shock
  3. Genome-Scale Acetylation-Dependent Histone Eviction during Spermatogenesis
  4. Lung Squamous Cell Carcinomas with Basaloid Histology Represent a Specific Molecular Entity
  5. The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway
  6. Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark
  7. Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription
  8. A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis
  9. Motor-driven marginal band coiling promotes cell shape change during platelet activation
  10. Sustaining cancer through addictive ectopic gene activation
  11. Histone variants and sensing of chromatin functional states
  12. Malignant genome reprogramming by ATAD2
  13. Cancer hallmarks sustained by ectopic activations of placenta/male germline genes
  14. Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B
  15. Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers
  16. Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers
  17. Research Highlights: Highlights from the latest articles in epigenomics
  18. When are the BET factors the most sensitive to bromodomain inhibitors?
  19. HDAC6 controls the kinetics of platelet activation
  20. Depletion of HDAC6 Enhances Cisplatin-Induced DNA Damage and Apoptosis in Non-Small Cell Lung Cancer Cells
  21. Bromodomain-dependent stage-specific male genome programming by Brdt
  22. Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy
  23. Combined proteomic andin silicoapproaches to decipher post-meiotic male genome reprogramming in mice
  24. A unified phylogeny-based nomenclature for histone variants
  25. Feux croisés sur le nucléosome
  26. Histone crotonylation specifically marks the haploid male germ cell gene expression program
  27. Proteomic strategy for the identification of critical actors in reorganization of the post-meiotic male genome
  28. Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification
  29. In the Heart of a Dynamic Chromatin
  30. Induced malignant genome reprogramming in somatic cells by testis-specific factors
  31. Differentiation of NUT Midline Carcinoma by Epigenomic Reprogramming
  32. Epigenetics and Human Reproduction
  33. The Tale of Protein Lysine Acetylation in the Cytoplasm
  34. Molecular models for post-meiotic male genome reprogramming
  35. Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin
  36. Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis
  37. Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains
  38. Making designer proteins: a facile acetyl-lysine mimic
  39. Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers
  40. 412 An acetylation/phosphorylation signalling network governs turn-over and activity of the splicing factor SC35 in response to cisplatin
  41. 1q12 chromosome translocations form aberrant heterochromatic foci associated with changes in nuclear architecture and gene expression in B cell lymphoma
  42. Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae
  43. Amphiregulin Promotes Resistance to Gefitinib in NonSmall Cell Lung Cancer Cells by Regulating Ku70 Acetylation
  44. Du nouveau dans la compréhension de la reprogrammation postméiotique du génome mâle
  45. From meiosis to postmeiotic events: The secrets of histone disappearance
  46. CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin
  47. New hypotheses for large-scale epigenome alterations in somatic cancer cells: a role for male germ-cell-specific regulators
  48. Parp2 is required for the differentiation of post-meiotic germ cells: Identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2
  49. Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
  50. Heat-Shock Factor 1 Controls Genome-wide Acetylation in Heat-shocked Cells
  51. Real-time imaging of histone H4 hyperacetylation in living cells
  52. Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6
  53. A transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells
  54. Spermiogenèse : l’acétylation des histones déclenche la reprogrammation du génome mâle
  55. Preface to the "Epigenetics and Development" Special Issue
  56. Chemical genomics: a key to the epigenome - An interview with Minoru Yoshida
  57. A new insight into male genome reprogramming by histone variants and histone code
  58. Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer
  59. HMGB4, a Novel Member of the HMGB Family, Is Preferentially Expressed in the Mouse Testis and Localizes to the Basal Pole of Elongating Spermatids
  60. L’Histone Acétyltransférase Tip60 régule l’activité biologique du facteur de transcription E2F1
  61. L’Amphiréguline induit la résistance au gefitinib des Cancers Bronchiques Non à Petites Cellules en contrôlant l’inactivation de BAX par Ku70
  62. Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells
  63. L’intrusion des régulateurs de l’épigénome mâle dans les cellules somatiques cancéreuses
  64. Regulation of protein turnover by acetyltransferases and deacetylases
  65. Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally
  66. HDAC6 a new cellular stress surveillance factor
  67. HDAC6, chef d’orchestre de la défense anti-agrégats protéiques
  68. Asymmetric nuclear reprogramming in somatic cell nuclear transfer?
  69. Testis-Specific Histone Variants H2AL1/2 Rapidly Disappear from Paternal Heterochromatin after Fertilization
  70. Epigenetic reprogramming of the male genome during gametogenesis and in the zygote
  71. Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222
  72. HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
  73. HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination
  74. Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis
  75. Differential histone modifications mark mouse imprinting control regions during spermatogenesis
  76. Post-meiotic Shifts in HSPA2/HSP70.2 Chaperone Activity during Mouse Spermatogenesis
  77. Épigénétique du spermatozoïde
  78. HDAC6–p97/VCP controlled polyubiquitin chain turnover
  79. p14ARF Activates a Tip60-Dependent and p53-Independent ATM/ATR/CHK Pathway in Response to Genotoxic Stress
  80. Assembly and mechanosensory function of focal adhesions: experiments and models
  81. RETRACTED ARTICLE: p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation
  82. Monitoring the interaction between DNA and a transcription factor (MEF2A) using fluorescence correlation spectroscopy
  83. 047 Le gène suppresseur de tumeur p14ARF induit l’accumulation de la protéine RB en inhibant son acétylation médiée par Tip60
  84. 044 La p14ARF active une voie ATM/ATR/CHK dépendante de l’histone acétyl-tranférase Tip60 en réponse aux agents génotoxiques
  85. Structural Characterization of the Histone Variant macroH2A
  86. HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses
  87. Testis-specific histone H3 expression in somatic cells
  88. Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression
  89. Establishment of male-specific epigenetic information
  90. Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability
  91. Expression of Serpinb6 serpins in germ and somatic cells of mouse gonads
  92. Differences in nuclear positioning of 1q12 pericentric heterochromatin in normal and tumor B lymphocytes with 1q rearrangements
  93. Role of the Tetradecapeptide Repeat Domain of Human Histone Deacetylase 6 in Cytoplasmic Retention
  94. Organisation nucléaire du spermatozoïde
  95. Organisation nucléaire du spermatozoïde
  96. The role of histones in chromatin remodelling during mammalian spermiogenesis
  97. Functional Interaction between Class II Histone Deacetylases and ICP0 of Herpes Simplex Virus Type 1
  99. HDAC6-induced premature chromatin compaction in mouse oocytes and fertilised eggs
  100. Différenciation du nucléosome : le rôle des variants de l’histone H2A
  101. HSP27 Is a Ubiquitin-Binding Protein Involved in I-κBα Proteasomal Degradation
  102. Cdyl: a new transcriptional co-repressor
  103. Chromatin and Epigenetics
  104. Acetylation-Dependent Chromatin Reorganization by BRDT, a Testis-Specific Bromodomain-Containing Protein
  105. Facteurs impliqués dans le remodelage de la chromatine au cours de la spermiogenèse
  106. The Histone Variant MacroH2A Interferes with Transcription Factor Binding and SWI/SNF Nucleosome Remodeling
  107. HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo
  108. The viral control of cellular acetylation signaling
  109. Tip60 Acetyltransferase Activity Is Controlled by Phosphorylation
  110. Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways
  111. Mechanism for Nucleocytoplasmic Shuttling of Histone Deacetylase 7
  112. Histone H1 diversity: bridging regulatory signals to linker histone function
  113. Histone deacetylase complexes: functional entities or molecular reservoirs
  114. Functional significance of histone deacetylase diversity
  115. Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin
  116. Higher concentrations of histone macroH2A in the Barr body are correlated with higher nucleosome density
  117. Involvement of Retinoblastoma Protein and HBP1 in Histone H10 Gene Expression
  118. Differential remodeling of the HIV-1 nucleosome upon transcription activators and SWI/SNF complex binding 1 1Edited by M. Yaniv
  119. Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm
  120. Ultraviolet Laser Footprinting of Histone H1°−Four-Way Junction DNA Complexes
  121. Control of the Histone-Acetyltransferase Activity of Tip60 by the HIV-1 Transactivator Protein, Tat
  122. Identification of a New Family of Higher Eukaryotic Histone Deacetylases: COORDINATE EXPRESSION OF DIFFERENTIATION-DEPENDENT CHROMATIN MODIFIERS
  123. Differential Recognition of Histone H10 by Monoclonal Antibodies during Cell Differentiation and the Arrest of Cell Proliferation
  124. The origin and utility of histone deacetylases
  125. Molecular Cloning and Cell Cycle-dependent Expression of Mammalian CRM1, a Protein Involved in Nuclear Export of Proteins
  126. Characterization of the two H1°-encoding genes from Xenopus laevis
  127. What do linker histones do in chromatin?
  128. The Evolution of the Differentiation-Specific Histone H1 Gene Basal Promoter
  129. Developmentally regulated expression of linker-histone variants in vertebrates
  130. Histone Acetylation Influences both Gene Expression and Development of Xenopus laevis
  132. Relationship between Core Histone Acetylation and Histone H10 Gene Activity
  133. Two mRNA species encoding the differentiation-associated histone H1o are produced by alternative polyadenylation in mouse
  134. Developmentally regulated expression of linker-histone variants in vertebrates
  135. Molecular basis of the activation of basal histone H1° gene expression
  136. Developmental regulation and butyrate-inducible transcription of the Xenopus histone HI° promoter
  137. Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.
  138. Antisense RNA and p53 Regulation in Induced Murine Cell Differentiation
  139. Induction of H10-gene expression in B16 murine melanoma cells
  140. Seric factors influence cell cycle modifications during commitment of murine erythroleukemia cells to differentiation
  141. Cell cycle-related accumulation of H10 mRNA: Induction in murine erythroleukemia cells
  142. Multiple control level governing H1omRNA and protein accumulation
  143. Modulation of B2 containing small RNAs during induced differentiation of murine erythroleukemia cells
  145. Regulation of histone H10 accumulation during induced differentiation of murine erythroleukemia cells
  146. Recovery of RNA from flow-sorted fixed cells
  147. Flow cytofluorimetric determination of protein distribution throughout the cell cycle
  148. Processing of p53 mRNA during induced differentiation of murine erythroleukemia cells: is an altered splicing mechanism responsible for the post-transcriptional control of gene expression?
  149. Early events in murine erythroleukemia cells induced to differentiate: Variation of the cell cycle parameters in relation to p53 accumulation
  150. Application of bromodeoxyuridine incorporation measurements to the determination of cell distribution within the S phase of the cell cycle
  151. Early events in murine erythroleukemia cells induced to differentiate
  152. In Situ Analysis of Chromatin Proteins During Development and Cell Differentiation Using Flow Cytometry
  153. UV Laser Footprinting and Protein-DNA Crosslinking Application to Chromatin
  154. How to Pack the Genome for a Safe Trip
  155. Histone Acetylation-Mediated Chromatin Compaction During Mouse Spermatogenesis