All Stories

  1. Author‐initiated repurposing of reviews: the Streamline Reviews initiative at Virology

    Article • Learned Publishing, April 2014, Wiley

    Dr Michael Emerman

  2. A Novel Bayesian Method for Detection of APOBEC3-Mediated Hypermutation and Its Application to Zoonotic Transmission of Simian Foamy Viruses

    Article • PLoS Computational Biology, February 2014, PLOS

    Dr Michael Emerman

  3. Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus

    Article • Proceedings of the National Academy of Sciences, December 2013, Proceedings of the National Academy of Sciences

    Dr Michael Emerman

  4. An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family

    Article • Genome Biology and Evolution, October 2013, Oxford University Press (OUP)

    Dr Michael Emerman, Dr Harmit Singh Malik

  5. Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations

    Article • Virology, September 2013, Elsevier

    Dr Michael Emerman

  6. The Mongoose, the Pheasant, the Pox, and the Retrovirus

    Article • PLoS Biology, August 2013, PLOS

    Dr Michael Emerman

  7. Host gene evolution traces the evolutionary history of ancient primate lentiviruses

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, August 2013, Royal Society Publishing

    Dr Michael Emerman, Dr Harmit Singh Malik

  8. An evolutionary perspective on the broad antiviral specificity of MxA

    Article • Current Opinion in Microbiology, August 2013, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  9. Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1

    Article • PLoS Pathogens, July 2013, PLOS

    Dr Michael Emerman

  10. Gene Loss and Adaptation to Hominids Underlie the Ancient Origin of HIV-1

    Article • Cell Host & Microbe, July 2013, Elsevier

    Dr Michael Emerman

  11. Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses

    Article • PLoS Pathogens, January 2013, PLOS

    Dr Michael Emerman

  12. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes

    Article • Proceedings of the National Academy of Sciences, January 2013, Proceedings of the National Academy of Sciences

    Dr Michael Emerman, Dr Harmit Singh Malik

  13. Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA

    Article • Cell Host & Microbe, October 2012, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  14. Evolutionary conflicts between viruses and restriction factors shape immunity

    Article • Nature Reviews Immunology, September 2012, Springer Science + Business Media

    Dr Michael Emerman

  15. The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses

    Article • Retrovirology, June 2012, Springer Science + Business Media

    Dr Michael Emerman, Dr Harmit Singh Malik

  16. The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

    Article • Cell Host & Microbe, February 2012, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  17. The Host Restriction Factor APOBEC3G and Retroviral Vif Protein Coevolve due to Ongoing Genetic Conflict

    Article • Cell Host & Microbe, January 2012, Elsevier

    Dr Michael Emerman

  18. The DEAD-box RNA Helicase DDX6 is Required for Efficient Encapsidation of a Retroviral Genome

    Article • PLoS Pathogens, October 2011, PLOS

    Dr Michael Emerman

  19. Paleovirology—ghosts and gifts of viruses past

    Article • Current Opinion in Virology, October 2011, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  20. The Little Book of Viruses

    Article • PLoS Biology, September 2011, PLOS

    Dr Michael Emerman

  21. The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection

    Article • Journal of Virology, August 2011, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  22. Polymorphism in Human APOBEC3H Affects a Phenotype Dominant for Subcellular Localization and Antiviral Activity

    Article • Journal of Virology, June 2011, ASM Journals

    Dr Michael Emerman

  23. Going for the watchman

    Article • Nature, June 2011, Springer Science + Business Media

    Dr Michael Emerman

  24. Trim5 TAKes on Pattern Recognition

    Article • Cell Host & Microbe, May 2011, Elsevier

    Dr Michael Emerman

  25. Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

    Article • Virology, January 2011, Elsevier

    Dr Michael Emerman

  26. Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses

    Article • Journal of Virology, May 2010, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  27. Paleovirology—Modern Consequences of Ancient Viruses

    Article • PLoS Biology, February 2010, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  28. The Range of Human APOBEC3H Sensitivity to Lentiviral Vif Proteins

    Article • Journal of Virology, October 2009, ASM Journals

    Dr Michael Emerman

  29. Simian Immunodeficiency Virus SIVagm from African Green Monkeys Does Not Antagonize Endogenous Levels of African Green Monkey Tetherin/BST-2

    Article • Journal of Virology, September 2009, ASM Journals

    Dr Michael Emerman

  30. Cellular Restriction Targeting Viral Capsids Perturbs Human Immunodeficiency Virus Type 1 Infection of Nondividing Cells

    Article • Journal of Virology, July 2009, ASM Journals

    Dr Michael Emerman

  31. Genetic Drift of HIV Populations in Culture

    Article • PLoS Genetics, March 2009, PLOS

    Dr Michael Emerman

  32. An expanded clade of rodent Trim5 genes

    Article • Virology, March 2009, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  33. Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

    Article • Journal of Virology, November 2008, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  34. Identification of Postentry Restrictions to Mason-Pfizer Monkey Virus Infection in New World Monkey Cells

    Article • Journal of Virology, September 2008, ASM Journals

    Dr Michael Emerman

  35. Determinants of cyclophilin A-dependent TRIM5α restriction against HIV-1

    Article • Virology, September 2008, Elsevier

    Dr Michael Emerman

  36. Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution

    Article • Cell Host & Microbe, September 2008, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  37. HIV-1 Accessory Proteins—Ensuring Viral Survival in a Hostile Environment

    Article • Cell Host & Microbe, June 2008, Elsevier

    Dr Michael Emerman

  38. Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

    Article • PLoS Genetics, January 2008, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  39. Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals

    Article • PLoS Pathogens, December 2007, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  40. Evidence for Direct Involvement of the Capsid Protein in HIV Infection of Nondividing Cells

    Article • PLoS Pathogens, October 2007, PLOS

    Dr Michael Emerman

  41. Primary Isolates of Human Immunodeficiency Virus Type 1 Are Usually Dominated by the Major Variants Found in Blood

    Article • Journal of Virology, July 2007, ASM Journals

    Dr Michael Emerman

  42. Restriction of an Extinct Retrovirus by the Human TRIM5  Antiviral Protein

    Article • Science, June 2007, American Association for the Advancement of Science

    Dr Michael Emerman, Dr Harmit Singh Malik

  43. Retroviral DNA Integration: Viral and Cellular Determinants of Target-Site Selection

    Article • PLoS Pathogens, June 2006, PLOS

    Dr Michael Emerman, Dr Joseph R Ecker

  44. Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H

    Article • Journal of Virology, April 2006, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  45. Uracil DNA Glycosylase Is Dispensable for Human Immunodeficiency Virus Type 1 Replication and Does Not Contribute to the Antiviral Effects of the Cytidine Deaminase Apobec3G

    Article • Journal of Virology, January 2006, ASM Journals

    Dr Michael Emerman

  46. Retroviral infection of non-dividing cells: Old and new perspectives

    Article • Virology, January 2006, Elsevier

    Dr Michael Emerman

  47. High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans

    Article • Current Biology, January 2006, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  48. Simian Immunodeficiency Virus Variants That Differ in Pathogenicity Differ in Fitness under Rapid Cell Turnover Conditions

    Article • Journal of Virology, December 2005, ASM Journals

    Dr Michael Emerman

  49. The Cell Cycle Independence of HIV Infections Is Not Determined by Known Karyophilic Viral Elements

    Article • PLoS Pathogens, November 2005, PLOS

    Dr Michael Emerman

  50. Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain

    Article • Proceedings of the National Academy of Sciences, February 2005, Proceedings of the National Academy of Sciences

    Dr Michael Emerman, Dr Harmit Singh Malik

  51. Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G

    Article • PLoS Biology, July 2004, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  52. Capsid Is a Dominant Determinant of Retrovirus Infectivity in Nondividing Cells

    Article • Journal of Virology, June 2004, ASM Journals

    Dr Michael Emerman

  53. Controlling lentiviruses: Single amino acid changes can determine specificity

    Article • Proceedings of the National Academy of Sciences, March 2004, Proceedings of the National Academy of Sciences

    Dr Michael Emerman

  54. The human immunodeficiency virus Vpr protein binds Cdc25C: implications for G2 arrest

    Article • Virology, January 2004, Elsevier

    Dr Michael Emerman

  55. Binding of Human Immunodeficiency Virus Type 1 to Immature Dendritic Cells Can Occur Independently of DC-SIGN and Mannose Binding C-Type Lectin Receptors via a Cholesterol-Dependent Pathway

    Article • Journal of Virology, December 2003, ASM Journals

    Dr Michael Emerman, Dr Suryaram Gummuluru

  56. Reassessment of the Roles of Integrase and the Central DNA Flap in Human Immunodeficiency Virus Type 1 Nuclear Import

    Article • Journal of Virology, December 2002, ASM Journals

    Dr Michael Emerman

  57. Dendritic Cell-Mediated Viral Transfer to T Cells Is Required for Human Immunodeficiency Virus Type 1 Persistence in the Face of Rapid Cell Turnover

    Article • Journal of Virology, November 2002, ASM Journals

    Dr Michael Emerman, Dr Suryaram Gummuluru

  58. Evidence for a cytopathogenicity determinant in HIV-1 Vpr

    Article • Proceedings of the National Academy of Sciences, July 2002, Proceedings of the National Academy of Sciences

    Dr Michael Emerman

  59. HIV-1 Vpr Does Not Inhibit CTL-Mediated Apoptosis of HIV-1 Infected Cells

    Article • Virology, March 2002, Elsevier

    Dr Michael Emerman

  60. Advances in HIV molecular biology

    Article • AIDS, January 2002, Wolters Kluwer Health

    Dr Michael Emerman, Dr Suryaram Gummuluru

  61. HIV-1 Infection Requires a Functional Integrase NLS

    Article • Molecular Cell, May 2001, Elsevier

    Dr Michael Emerman

  62. HIV-1 Sequence Variation

    Article • Cell, February 2001, Elsevier

    Dr Michael Emerman

  63. An In Vitro Rapid-Turnover Assay for Human Immunodeficiency Virus Type 1 Replication Selects for Cell-to-Cell Spread of Virus

    Article • Journal of Virology, December 2000, ASM Journals

    Dr Michael Emerman, Dr Suryaram Gummuluru

  64. A competition model for viral inhibition of host cell proliferation

    Article • Mathematical Biosciences, July 2000, Elsevier

    Dr Michael Emerman

  65. Direct detection of infectious HIV-1 in blood using a centrifugation-indicator cell assay

    Article • Journal of Virological Methods, July 2000, Elsevier

    Dr Michael Emerman

  66. Protection against Human Immunodeficiency Virus Type 1 Infection in Persons with Repeated Exposure: Evidence for T Cell Immunity in the Absence of Inherited CCR5 Coreceptor Defects

    Article • The Journal of Infectious Diseases, March 1999, Oxford University Press (OUP)

    Dr Michael Emerman

  67. HIV-1 Regulatory/Accessory Genes: Keys to Unraveling Viral and Host Cell Biology

    Article • Science, June 1998, American Association for the Advancement of Science

    Dr Michael Emerman

  68. HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

    Article • Genes & Development, January 1998, Cold Spring Harbor Laboratory Press

    Dr Michael Emerman

  69. HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo

    Article • Nature Medicine, January 1998, Springer Science + Business Media

    Dr Michael Emerman

  70. Indicator Cell Lines for Detection of Primary Strains of Human and Simian Immunodeficiency Viruses

    Article • Virology, June 1997, Elsevier

    Dr Michael Emerman

  71. Gene acquisition in HIV and SIV

    Article • Nature, October 1996, Springer Science + Business Media

    Dr Michael Emerman

  72. HIV-1, Vpr and the cell cycle

    Article • Current Biology, September 1996, Elsevier

    Dr Michael Emerman

  73. From curse to cure: HIV for gene therapy?

    Article • Nature Biotechnology, August 1996, Springer Science + Business Media

    Dr Michael Emerman

  74. Vpx Association with Mature Core Structures of HIV-2

    Article • Virology, April 1996, Elsevier

    Dr Michael Emerman

  75. Protein Stability Influences Human Immunodeficiency Virus Type 2 Vpr Virion Incorporation and Cell Cycle Effect

    Article • Virology, April 1996, Elsevier

    Dr Michael Emerman

  76. [12] Quantitation of virus stocks produced from cloned human immunodeficiency virus DNA

    Article • January 1995, Elsevier

    Dr Michael Emerman

  77. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

    Article • Proceedings of the National Academy of Sciences, July 1994, Proceedings of the National Academy of Sciences

    Dr Michael Emerman

  78. Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts.

    Article • Proceedings of the National Academy of Sciences, April 1994, Proceedings of the National Academy of Sciences

    Dr Michael Emerman

  79. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

    Article • Nature, October 1993, Springer Science + Business Media

    Dr Michael Emerman

  80. Functional mapping of the rev-responsive element of human immunodeficiency virus type 2 (HIV-2): influence of HIV-2 envelope-encoding sequences on HIV-1 gp120 expression in the presence or absence of Rev

    Article • Journal of General Virology, July 1992, Society for General Microbiology

    Dr Michael Emerman

  81. Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI

    Article • Virology, December 1991, Elsevier

    Dr Michael Emerman

  82. Single amino-acid changes in HIV envelope affect viral tropism and receptor binding

    Article • Nature, August 1989, Springer Science + Business Media

    Dr Michael Emerman

  83. The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

    Article • Cell, June 1989, Elsevier

    Dr Michael Emerman

  84. Genome organization and transactivation of the human immunodeficiency virus type 2

    Article • Nature, April 1987, Springer Science + Business Media

    Dr Michael Emerman

  85. Comparison of promoter suppression in avian and murine retrovirus vectors

    Article • Nucleic Acids Research, January 1986, Oxford University Press (OUP)

    Dr Michael Emerman

  86. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism

    Article • Cell, December 1984, Elsevier

    Dr Michael Emerman