All Stories

  1. Structural modeling and experimental validation define the MxA-Thogotovirus nucleoprotein interface that drives restriction and escape

    Article • August 2026, openRxiv

    Dr Harmit Singh Malik

  2. Strain-specific epistasis shapes fitness landscapes of APOBEC3G antagonism by HIV-1 Vif proteins

    Article • Science Advances, July 2026, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  3. Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

    Article • Science Advances, July 2026, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  4. A conserved in-frame stop codon acts as a multipotent defense mechanism in alphaviruses

    Article • Science Advances, June 2026, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  5. Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

    Article • March 2026, openRxiv

    Dr Harmit Singh Malik

  6. Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs

    Article • PLoS Biology, March 2026, PLOS

    Dr Harmit Singh Malik

  7. The Drosophila maternal-effect gene abnormal oocyte ( ao ) does not repress histone gene expression

    Article • Genetics, February 2026, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  8. Retention of a single Cenp-C gene in different syntenic locations in the montium group of Drosophila species

    Article • December 2025, openRxiv

    Dr Harmit Singh Malik

  9. Dynamic evolution of EZHIP, an inhibitor of the Polycomb Repressive Complex 2 in mammals

    Article • December 2025, openRxiv

    Dr Harmit Singh Malik

  10. Fitness Landscapes of APOBEC3G Antagonism by HIV-1 Vif proteins

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  11. The Sindbis virus nsP3 opal codon protects viral RNA and fitness by maintaining replication spherule integrity

    Article • September 2025, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  12. Molecular exaptation by the integrin αI domain

    Article • Science Advances, September 2025, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  13. Rapid protamine evolution suppresses meiotic drive in Drosophila

    Article • September 2025, openRxiv

    Dr Harmit Singh Malik

  14. The viral arms race: an interview with Harmit Malik

    Article • Disease Models & Mechanisms, September 2025, The Company of Biologists

    Dr Harmit Singh Malik

  15. Yellow Fever Virus Interactomes Reveal Common and Divergent Strategies of Replication and Evolution for Mosquito-borne Flaviviruses

    Article • June 2025, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  16. Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

    Article • Cell Genomics, June 2025, Elsevier

    Dr Harmit Singh Malik

  17. Heterozygous and generalist MxA super-restrictors overcome breadth-specificity trade-offs in antiviral restriction

    Article • Science Advances, May 2025, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  18. A conserved opal termination codon optimizes a temperature-dependent trade-off between protein production and processing in alphaviruses

    Article • Science Advances, April 2025, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  19. Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

    Article • Proceedings of the National Academy of Sciences, January 2025, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  20. Magnesium depletion unleashes two unusual modes of colistin resistance with different fitness costs

    Article • October 2024, Cold Spring Harbor Laboratory Press

    Dr Robert Ernst, Dr Harmit Singh Malik

  21. Heterozygous and generalist MxA super-restrictors overcome breadth-specificity tradeoffs in antiviral restriction

    Article • October 2024, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  22. Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213

    Article • EMBO Reports, October 2024, Springer Science + Business Media

    Dr Harmit Singh Malik

  23. TheDrosophilamaternal-effect geneabnormal oocyte(ao) does not repress histone gene expression

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  24. A conserved opal termination codon optimizes a temperature-dependent tradeoff between protein production and processing in alphaviruses

    Article • August 2024, openRxiv

    Dr Harmit Singh Malik

  25. Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

    Article • August 2024, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  26. Widespread fungal–bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibiotics

    Article • PLoS Biology, June 2024, PLOS

    Dr Harmit Singh Malik

  27. Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  28. The diverse evolutionary histories of domesticated metaviral capsid genes in mammals

    Article • Molecular Biology and Evolution, March 2024, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  29. Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins

    Article • November 2023, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  30. Expansion and loss of sperm nuclear basic protein genes in Drosophila correspond with genetic conflicts between sex chromosomes

    Article • eLife, February 2023, eLife

    Dr Harmit Singh Malik

  31. Driving lessons: a brief (personal) history of centromere drive

    Article • Genetics, November 2022, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  32. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species

    Article • Molecular Biology and Evolution, September 2022, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  33. Genetic conflicts between sex chromosomes drive expansion and loss of sperm nuclear basic protein genes in Drosophila

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  34. Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  35. Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline

    Article • Molecular Biology and Evolution, January 2022, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  36. The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity

    Article • PLoS Biology, October 2021, PLOS

    Dr Harmit Singh Malik

  37. Novel classes and evolutionary turnover of histone H2B variants in the mammalian germline

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  38. An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development

    Article • eLife, July 2021, eLife

    Dr Harmit Singh Malik

  39. Gametic specialization of centromeric histone paralogs in Drosophila virilis

    Article • Life Science Alliance, May 2021, Life Science Alliance, LLC

    Dr Harmit Singh Malik

  40. Putting the brakes on centromere drive in Mimulus

    Article • PLoS Genetics, April 2021, PLOS

    Dr Harmit Singh Malik

  41. A balancing act between primate lentiviruses and their receptor

    Article • Proceedings of the National Academy of Sciences, April 2021, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  42. Biparental contributions of the H2A.B histone variant control embryonic development in mice

    Article • PLoS Biology, December 2020, PLOS

    Dr Harmit Singh Malik

  43. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila

    Article • eLife, November 2020, eLife

    Dr Harmit Singh Malik

  44. A natural variant of the essential host gene MMS21 restricts the parasitic 2-micron plasmid in Saccharomyces cerevisiae

    Article • eLife, October 2020, eLife

    Dr Harmit Singh Malik

  45. AcrIIA22 is a novel anti-CRISPR that impairs SpyCas9 activity by relieving DNA torsion of target plasmids

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  46. A rapidly evolving actin mediates fertility and developmental tradeoffs in Drosophila

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  47. Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

    Article • eLife, September 2020, eLife

    Dr Harmit Singh Malik

  48. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  49. Natural variation in an essential host gene contributes to parasitic plasmid resistance in Saccharomyces cerevisiae

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  50. Ancient Coretention of Paralogs of Cid Centromeric Histones and Cal1 Chaperones in Mosquito Species

    Article • Molecular Biology and Evolution, March 2020, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  51. Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes

    Article • Molecular Biology and Evolution, February 2020, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  52. Hybridization promotes asexual reproduction in Caenorhabditis nematodes

    Article • PLoS Genetics, December 2019, PLOS

    Dr Harmit Singh Malik

  53. Meiosis: How Gambling Chromosomes Beat the Rules

    Article • Current Biology, December 2019, Elsevier

    Dr Harmit Singh Malik

  54. A Burst of Genetic Innovation in Drosophila Actin-Related Proteins for Testis-Specific Function

    Article • Molecular Biology and Evolution, November 2019, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  55. Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins

    Article • PLoS Biology, October 2019, PLOS

    Dr Harmit Singh Malik

  56. Dynamic evolution of de novo DNA methyltransferases in rodent and primate genomes

    Article • September 2019, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  57. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

    Article • eLife, September 2019, eLife

    Dr Harmit Singh Malik

  58. A burst of genetic innovation in actin-related proteins (Arps) for testis-specific function in a Drosophila lineage

    Article • June 2019, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  59. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA

    Article • eLife, May 2019, eLife

    Dr Harmit Singh Malik

  60. Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  61. Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  62. Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  63. Gametic specialization of centromeric histone paralogs in Drosophila virilis

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  64. Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA

    Article • August 2018, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  65. The cellular mechanisms and consequences of centromere drive

    Article • Current Opinion in Cell Biology, June 2018, Elsevier

    Dr Harmit Singh Malik

  66. Kindr Motors Drive in Meiosis

    Article • Cell, May 2018, Elsevier

    Dr Harmit Singh Malik

  67. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals

    Article • Genome Research, March 2018, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  68. Culture shock

    Article • eLife, December 2017, eLife

    Dr Harmit Singh Malik

  69. Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals

    Article • July 2017, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  70. The gene drive bubble: New realities

    Article • PLoS Genetics, July 2017, PLOS

    Dr Harmit Singh Malik

  71. wtf genes are prolific dual poison-antidote meiotic drivers

    Article • eLife, June 2017, eLife

    Dr Harmit Singh Malik

  72. Recurrent Gene Duplication Leads to Diverse Repertoires of Centromeric Histones in Drosophila Species

    Article • Molecular Biology and Evolution, February 2017, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  73. Genetic conflicts: the usual suspects and beyond

    Article • Journal of Experimental Biology, January 2017, The Company of Biologists

    Dr Harmit Singh Malik

  74. The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila ...

    Article • Genes & Development, December 2016, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  75. Recurrent gene duplication leads to diverse repertoires of centromeric histones in Drosophila species

    Article • November 2016, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  76. Did a Single Amino Acid Change Make Ebola Virus More Virulent?

    Article • Cell, November 2016, Elsevier

    Dr Harmit Singh Malik

  77. A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility inDrosophila melanogaster

    Article • eLife, August 2016, eLife

    Dr Harmit Singh Malik

  78. Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals

    Article • eLife, May 2016, eLife

    Dr Harmit Singh Malik

  79. Evolution of a transcriptional regulator from a transmembrane nucleoporin

    Article • Genes & Development, May 2016, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  80. Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution

    Article • Molecular Biology and Evolution, April 2016, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  81. Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline

    Article • Current Opinion in Genetics & Development, April 2016, Elsevier

    Dr Harmit Singh Malik

  82. Recurrent gene duplication diversifies genome defense repertoire in Drosophila

    Article • Molecular Biology and Evolution, March 2016, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  83. Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?

    Article • Trends in Cell Biology, February 2016, Elsevier

    Dr Harmit Singh Malik

  84. An essential cell cycle regulation gene causes hybrid inviability in Drosophila

    Article • Science, December 2015, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  85. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction

    Article • PLoS Pathogens, December 2015, PLOS

    Dr Harmit Singh Malik

  86. Chromosome Segregation: Human Female Meiosis Breaks All the Rules

    Article • Current Biology, August 2015, Elsevier

    Dr Harmit Singh Malik

  87. LINE-1 Retroelements Get ZAPped!

    Article • PLoS Genetics, July 2015, PLOS

    Dr Harmit Singh Malik

  88. Mitotic fidelity requires transgenerational action of a testis-restricted HP1

    Article • eLife, July 2015, eLife

    Dr Harmit Singh Malik

  89. R2d2 and Hyperdrive Mechanisms (in Mouse Meiosis)

    Article • PLoS Genetics, February 2015, PLOS

    Dr Harmit Singh Malik

  90. Speciation via Autoimmunity: A Dangerous Mix

    Article • Cell, December 2014, Elsevier

    Dr Harmit Singh Malik

  91. Transferred interbacterial antagonism genes augment eukaryotic innate immune function

    Article • Nature, November 2014, Nature

    Dr Harmit Singh Malik

  92. Genetic Conflicts: Stronger Centromeres Win Tug-of-War in Female Meiosis

    Article • Current Biology, October 2014, Elsevier

    Dr Harmit Singh Malik

  93. Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects

    Article • eLife, September 2014, eLife

    Steven Henikoff, Dr Harmit Singh Malik

  94. How a Virus Blocks a Cellular Emergency Access Lane to the Nucleus, STAT!

    Article • Cell Host & Microbe, August 2014, Elsevier

    Dr Harmit Singh Malik

  95. Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast

    Article • eLife, June 2014, eLife

    Dr Harmit Singh Malik

  96. Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts

    Article • PLoS Genetics, May 2014, PLOS

    Dr Harmit Singh Malik

  97. Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes

    Article • Molecular Cell, April 2014, Elsevier

    Dr Harmit Singh Malik

  98. Mobile DNA: an evolving field

    Article • Mobile DNA, January 2014, Springer Science + Business Media

    Dr Harmit Singh Malik

  99. Mobile genetic elements and genome evolution 2014

    Article • Mobile DNA, January 2014, Springer Science + Business Media

    Dr Harmit Singh Malik

  100. An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family

    Article • Genome Biology and Evolution, October 2013, Oxford University Press (OUP)

    Dr Michael Emerman, Dr Harmit Singh Malik

  101. Host gene evolution traces the evolutionary history of ancient primate lentiviruses

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, August 2013, Royal Society Publishing

    Dr Michael Emerman, Dr Harmit Singh Malik

  102. An evolutionary perspective on the broad antiviral specificity of MxA

    Article • Current Opinion in Microbiology, August 2013, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  103. A rapidly evolving genomic toolkit forDrosophilaheterochromatin

    Article • Fly, July 2013, Taylor & Francis

    Dr Harmit Singh Malik

  104. Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes

    Article • Proceedings of the National Academy of Sciences, July 2013, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  105. Stepwise Evolution of Essential Centromere Function in a Drosophila Neogene

    Article • Science, June 2013, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  106. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes

    Article • Proceedings of the National Academy of Sciences, January 2013, Proceedings of the National Academy of Sciences

    Dr Michael Emerman, Dr Harmit Singh Malik

  107. Rules of Engagement: Molecular Insights from Host-Virus Arms Races

    Article • Annual Review of Genetics, December 2012, Annual Reviews

    Dr Harmit Singh Malik

  108. Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

    Article • Journal of Experimental Medicine, October 2012, Rockefeller University Press

    Dr Harmit Singh Malik

  109. Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA

    Article • Cell Host & Microbe, October 2012, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  110. Poxviruses Deploy Genomic Accordions to Adapt Rapidly against Host Antiviral Defenses

    Article • Cell, August 2012, Elsevier

    Dr Harmit Singh Malik

  111. Rapid evolution of centromeres and centromeric/kinetochore proteins

    Article • June 2012, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  112. The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses

    Article • Retrovirology, June 2012, Springer Science + Business Media

    Dr Michael Emerman, Dr Harmit Singh Malik

  113. Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family

    Article • PLoS Genetics, June 2012, PLOS

    Dr Harmit Singh Malik

  114. A unified phylogeny-based nomenclature for histone variants

    Article • Epigenetics & Chromatin, May 2012, Springer Science + Business Media

    Dr Saadi Khochbin, Dr Harmit Singh Malik

  115. Convergent Evolution of Escape from Hepaciviral Antagonism in Primates

    Article • PLoS Biology, March 2012, PLOS

    Dr Harmit Singh Malik

  116. The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

    Article • Cell Host & Microbe, February 2012, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  117. Retroviruses push the envelope for mammalian placentation

    Article • Proceedings of the National Academy of Sciences, January 2012, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  118. Birth, Death, and Replacement of Karyopherins in Drosophila

    Article • Molecular Biology and Evolution, December 2011, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  119. Learning to Protect Your Genome on the Fly

    Article • Cell, December 2011, Elsevier

    Dr Harmit Singh Malik

  120. Adaptive Evolution of Centromeric Proteins

    Article • November 2011, Wiley

    Dr Harmit Singh Malik

  121. Paleovirology—ghosts and gifts of viruses past

    Article • Current Opinion in Virology, October 2011, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  122. The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection

    Article • Journal of Virology, August 2011, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  123. Absence of Positive Selection on Centromeric Histones in Tetrahymena Suggests Unsuppressed Centromere-Drive in Lineages Lacking Male Meiosis

    Article • Journal of Molecular Evolution, June 2011, Springer Science + Business Media

    Dr Harmit Singh Malik

  124. Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses

    Article • Journal of Virology, May 2010, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  125. Paleovirology—Modern Consequences of Ancient Viruses

    Article • PLoS Biology, February 2010, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  126. Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces

    Article • BMC Evolutionary Biology, January 2010, Springer Science + Business Media

    Dr Harmit Singh Malik

  127. Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa

    Article • PLoS Genetics, December 2009, PLOS

    Dr Harmit Singh Malik, A/Prof Scott A Beatson

  128. Multiple Roles for Heterochromatin Protein 1 Genes inDrosophila

    Article • Annual Review of Genetics, December 2009, Annual Reviews

    Dr Harmit Singh Malik

  129. Diamonds and rust: how transposable elements influence mammalian genomes

    Article • EMBO Reports, November 2009, EMBO

    Dr Harmit Singh Malik

  130. Altered Heterochromatin Binding by a Hybrid Sterility Protein in Drosophila Sibling Species

    Article • Science, October 2009, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  131. The evolutionary conundrum of pathogen mimicry

    Article • Nature Reviews Microbiology, October 2009, Springer Science + Business Media

    Dr Harmit Singh Malik

  132. Major Evolutionary Transitions in Centromere Complexity

    Article • Cell, September 2009, Elsevier

    Dr Harmit Singh Malik

  133. Evolution of TRIM antiviral genes in primate genomes

    Article • Retrovirology, September 2009, Springer Science + Business Media

    Dr Harmit Singh Malik

  134. A Surrogate Approach to Study the Evolution of Noncoding DNA Elements That Organize Eukaryotic Genomes

    Article • Journal of Heredity, July 2009, Oxford University Press (OUP)

    Dr Harmit Singh Malik

  135. The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions

    Article • Genome Research, March 2009, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  136. An expanded clade of rodent Trim5 genes

    Article • Virology, March 2009, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  137. The Centromere-Drive Hypothesis: A Simple Basis for Centromere Complexity

    Article • January 2009, Springer Science + Business Media

    Dr Harmit Singh Malik

  138. Protein kinase R reveals an evolutionary model for defeating viral mimicry

    Article • Nature, November 2008, Springer Science + Business Media

    Dr Harmit Singh Malik

  139. Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

    Article • Journal of Virology, November 2008, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  140. Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution

    Article • Cell Host & Microbe, September 2008, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  141. The Evolution of Centromeric DNA Sequences

    Article • April 2008, Wiley

    Dr Harmit Singh Malik

  142. Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

    Article • PLoS Genetics, January 2008, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  143. Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals

    Article • PLoS Pathogens, December 2007, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  144. Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila

    Article • Proceedings of the National Academy of Sciences, September 2007, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  145. Restriction of an Extinct Retrovirus by the Human TRIM5  Antiviral Protein

    Article • Science, June 2007, American Association for the Advancement of Science

    Dr Michael Emerman, Dr Harmit Singh Malik

  146. Molecular Evolution of Drosophilacdc6, an Essential DNA Replication-Licensing Gene, Suggests an Adaptive Choice of Replication Origins

    Article • Fly, May 2007, Taylor & Francis

    Dr Harmit Singh Malik

  147. Genes get diabolical

    Article • Nature Genetics, May 2007, Springer Science + Business Media

    Dr Harmit Singh Malik

  148. Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis

    Article • Proceedings of the National Academy of Sciences, November 2006, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  149. A hitchhiker's guide to survival finally makes CENs

    Article • Journal of Cell Biology, September 2006, Rockefeller University Press

    Dr Harmit Singh Malik

  150. Genetic conflicts during meiosis and the evolutionary origins of centromere complexity: Figure 1

    Article • Biochemical Society Transactions, August 2006, Portland Press Ltd.

    Dr Harmit Singh Malik

  151. Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H

    Article • Journal of Virology, April 2006, ASM Journals

    Dr Michael Emerman, Dr Harmit Singh Malik

  152. High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans

    Article • Current Biology, January 2006, Elsevier

    Dr Michael Emerman, Dr Harmit Singh Malik

  153. The CNA1 Histone of the Ciliate Tetrahymena thermophila Is Essential for Chromosome Segregation in the Germline Micronucleus

    Article • Molecular Biology of the Cell, November 2005, American Society for Cell Biology (ASCB)

    Dr Harmit Singh Malik

  154. finds centromeres in the driver's seat

    Article • Trends in Ecology & Evolution, April 2005, Elsevier

    Dr Harmit Singh Malik

  155. Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain

    Article • Proceedings of the National Academy of Sciences, February 2005, Proceedings of the National Academy of Sciences

    Dr Michael Emerman, Dr Harmit Singh Malik

  156. Ribonuclease H evolution in retrotransposable elements

    Article • Cytogenetic and Genome Research, January 2005, Karger Publishers

    Dr Harmit Singh Malik

  157. Positive Selection of Iris, a Retroviral Envelope–Derived Host Gene in Drosophila melanogaster

    Article • PLoS Genetics, January 2005, PLOS

    Dr Harmit Singh Malik

  158. Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila

    Article • PLoS Genetics, January 2005, PLOS

    Dr Harmit Singh Malik

  159. Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G

    Article • PLoS Biology, July 2004, PLOS

    Dr Michael Emerman, Dr Harmit Singh Malik

  160. Phylogenomics of the nucleosome

    Article • Nature Structural & Molecular Biology, October 2003, Springer Science + Business Media

    Dr Harmit Singh Malik

  161. Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9

    Article • RNA, May 2003, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  162. Conflict begets complexity: the evolution of centromeres

    Article • Current Opinion in Genetics & Development, December 2002, Elsevier

    Dr Harmit Singh Malik

  163. Centromeres: Selfish drivers

    Article • Nature, May 2002, Springer Science + Business Media

    Dr Harmit Singh Malik

  164. Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone

    Article • Proceedings of the National Academy of Sciences, January 2002, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  165. Origins and Evolution of Retrotransposons

    Article • January 2002, ASM Journals

    Dr Harmit Singh Malik

  166. Speciation and Centromere Evolution

    Article • Science, December 2001, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  167. The Centromere Paradox: Stable Inheritance with Rapidly Evolving DNA

    Article • Science, August 2001, American Association for the Advancement of Science

    Dr Harmit Singh Malik

  168. Phylogenetic Analysis of Ribonuclease H Domains Suggests a Late, Chimeric Origin of LTR Retrotransposable Elements and Retroviruses

    Article • Genome Research, July 2001, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  169. Ten-Kilodalton Domain in Ty3 Gag3-Pol3p between PR and RT Is Dispensable for Ty3 Transposition

    Article • Journal of Virology, February 2001, ASM Journals

    Dr Harmit Singh Malik

  170. Dual recognition–incision enzymes might be involved in mismatch repair and meiosis

    Article • Trends in Biochemical Sciences, September 2000, Elsevier

    Dr Harmit Singh Malik

  171. Poised for Contagion: Evolutionary Origins of the Infectious Abilities of Invertebrate Retroviruses

    Article • Genome Research, September 2000, Cold Spring Harbor Laboratory Press

    Dr Harmit Singh Malik

  172. Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans

    Article • Gene, June 2000, Elsevier

    Dr Harmit Singh Malik

  173. A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli

    Article • Proceedings of the National Academy of Sciences, November 1998, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik

  174. Are retrotransposons long-term hitchhikers?

    Article • Nature, March 1998, Springer Science + Business Media

    Dr Harmit Singh Malik

  175. Evolutionary specialization of the nuclear targeting apparatus

    Article • Proceedings of the National Academy of Sciences, December 1997, Proceedings of the National Academy of Sciences

    Dr Harmit Singh Malik