All Stories

  1. Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder

    Article • Neuropharmacology, September 2016, Elsevier

    Daryl L Davies

  2. P2X4 receptors regulate dopamine neurotransmission

    Article • Journal of Neurochemistry, August 2016, Wiley

    Daryl L Davies, Sheraz Khoja

  3. Sex and the Lab: An Alcohol-Focused Commentary on the NIH Initiative to Balance Sex in Cell and Animal Studies

    Article • Alcoholism Clinical and Experimental Research, May 2016, Wiley

    Daryl L Davies

  4. A Pilot Study of the Safety and Initial Efficacy of Ivermectin for the Treatment of Alcohol Use Disorder

    Article • Alcoholism Clinical and Experimental Research, April 2016, Wiley

    Daryl L Davies, Daniel Roche

  5. Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals

    Article • Journal of Visualized Experiments, March 2016, MyJove Corporation

    Daryl L Davies

  6. Oral delivery of ivermectin using a fast dissolving oral film: Implications for repurposing ivermectin as a pharmacotherapy for alcohol use disorder

    Article • Alcohol, September 2015, Elsevier

    Daryl L Davies

  7. Chronic ethanol exposure combined with high fat diet up-regulates P2X7 receptors that parallels neuroinflammation and neuronal loss in C57BL/6J mice

    Article • Journal of Neuroimmunology, August 2015, Elsevier

    Daryl L Davies, Sheraz Khoja

  8. The Importance of Animals in Advancing Research on Alcohol Use Disorders

    Article • Alcoholism Clinical and Experimental Research, April 2015, Wiley

    Daryl L Davies

  9. Multiday administration of ivermectin is effective in reducing alcohol intake in mice at doses shown to be safe in humans

    Article • Neuroreport, September 2014, Wolters Kluwer Health

    Daryl L Davies

  10. P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders

    Article • Frontiers in Neuroscience, June 2014, Frontiers

    Daryl L Davies

  11. Contribution of P2X4 Receptors to Ethanol Intake in Male C57BL/6 Mice

    Article • Neurochemical Research, March 2014, Springer Science + Business Media

    Daryl L Davies, Sheraz Khoja

  12. Avermectins differentially affect ethanol intake and receptor function: implications for developing new therapeutics for alcohol use disorders

    Article • The International Journal of Neuropsychopharmacology, January 2014, Oxford University Press (OUP)

    Daryl L Davies, Professor Nicos A. Petasis

  13. Structural Models of Ligand-Gated Ion Channels: Sites of Action for Anesthetics and Ethanol

    Article • Alcoholism Clinical and Experimental Research, October 2013, Wiley

    Daryl L Davies

  14. Tryptophan 46 is a site for ethanol and ivermectin action in P2X4 receptors

    Article • Purinergic Signalling, July 2013, Springer Science + Business Media

    Daryl L Davies

  15. Sociocommunicative and Sensorimotor Impairments in Male P2X4-Deficient Mice

    Article • Neuropsychopharmacology, April 2013, Nature

    Daryl L Davies, Sheraz Khoja

  16. Pharmacological insights into the role of P2X4 receptors in behavioural regulation: lessons from ivermectin

    Article • The International Journal of Neuropsychopharmacology, September 2012, Oxford University Press (OUP)

    Daryl L Davies, Sheraz Khoja

  17. Ivermectin reduces alcohol intake and preference in mice

    Article • Neuropharmacology, August 2012, Elsevier

    Professor Nicos A. Petasis, Daryl L Davies, Sheraz Khoja

  18. Recent Advances in the Discovery and Preclinical Testing of Novel Compounds for the Prevention and/or Treatment of Alcohol Use Disorders

    Article • Alcoholism Clinical and Experimental Research, June 2012, Wiley

    Daryl L Davies

  19. Alcohol-Binding Sites in Distinct Brain Proteins: The Quest for Atomic Level Resolution

    Article • Alcoholism Clinical and Experimental Research, June 2011, Wiley

    Daryl L Davies

  20. Implication of the Purinergic System in Alcohol Use Disorders

    Article • Alcoholism Clinical and Experimental Research, January 2011, Wiley

    Daryl L Davies

  21. Functional Role of the Intracellular Loop Linking Transmembrane Domains 6 and 7 of the Human Dipeptide Transporter hPEPT1

    Article • The Journal of Membrane Biology, November 2010, Springer Science + Business Media

    Daryl L Davies

  22. Molecular targets and mechanisms for ethanol action in glycine receptors

    Article • Pharmacology & Therapeutics, July 2010, Elsevier

    Daryl L Davies

  23. A point mutation in the ectodomain-transmembrane 2 interface eliminates the inhibitory effects of ethanol in P2X4 receptors

    Article • Journal of Neurochemistry, January 2010, Wiley

    Daryl L Davies

  24. Mutagenesis and Cysteine Scanning of Transmembrane Domain 10 of the Human Dipeptide Transporter

    Article • Pharmaceutical Research, August 2009, Springer Science + Business Media

    Daryl L Davies

  25. Loop 2 Structure in Glycine and GABAAReceptors Plays a Key Role in Determining Ethanol Sensitivity

    Article • Journal of Biological Chemistry, August 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Daryl L Davies

  26. Molecular Weight and Volume at Position 46 in Transmembrane Domain 1 (TM1) are Important Determinants for Ethanol Sensitivity in P2X4 Receptors

    Article • Biophysical Journal, February 2009, Elsevier

    Daryl L Davies

  27. Roles of ectodomain and transmembrane regions in ethanol and agonist action in purinergic P2X2 and P2X3 receptors

    Article • Neuropharmacology, October 2008, Elsevier

    Daryl L Davies

  28. Targets for ethanol action and antagonism in Loop 2 of the extracellular domain of glycine receptors

    Article • Journal of Neurochemistry, August 2008, Wiley

    Daryl L Davies

  29. Ethanol Inhibits Functional Activity of the Human Intestinal Dipeptide Transporter hPepT1 Expressed in Xenopus Oocytes

    Article • Alcoholism Clinical and Experimental Research, May 2008, Wiley

    Daryl L Davies

  30. Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of α1 glycine receptors

    Article • Journal of Neurochemistry, May 2007, Wiley

    Daryl L Davies

  31. Cysteine scanning of transmembrane domain three of the human dipeptide transporter: Implications for substrate transport

    Article • Journal of Drug Targeting, January 2007, Taylor & Francis

    Daryl L Davies

  32. A Charge Pair Interaction Between Arg282 in Transmembrane Segment 7 and Asp341 in Transmembrane Segment 8 of hPepT1

    Article • Pharmaceutical Research, September 2006, Springer Science + Business Media

    Daryl L Davies

  33. Effects of Ethanol on Adenosine 5'-Triphosphate-Gated Purinergic and 5-Hydroxytryptamine3 Receptors

    Article • Alcoholism Clinical and Experimental Research, February 2006, Wiley

    Daryl L Davies

  34. Propofol acts on different sites than ethanol and butanol in recombinant glycine receptors: Evidence from pressure studies

    Article • International Congress Series, November 2005, Elsevier

    Daryl L Davies

  35. Effects of the abused solvent toluene on recombinant P2X receptors expressed in HEK293 cells

    Article • Molecular Brain Research, June 2004, Elsevier

    Daryl L Davies

  36. Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism

    Article • Journal of Neurochemistry, June 2004, Wiley

    Daryl L Davies

  37. Biophysical Evidence for His 57 as a Proton-Binding Site in the Mammalian Intestinal Transporter hPepT1

    Article • Pharmaceutical Research, December 2003, Springer Science + Business Media

    Daryl L Davies

  38. Benzodiazepine agonist and inverse agonist coupling in GABAA receptors antagonized by increased atmospheric pressure

    Article • European Journal of Pharmacology, May 2003, Elsevier

    Daryl L Davies

  39. Ethanol Potentiation of Glycine Receptors Expressed in Xenopus Oocytes Antagonized by Increased Atmospheric Pressure

    Article • Alcoholism Clinical and Experimental Research, May 2003, Wiley

    Daryl L Davies

  40. Ethanol Sensitivity in ATP-Gated P2X Receptors Is Subunit Dependent

    Article • Alcoholism Clinical and Experimental Research, June 2002, Wiley

    Daryl L Davies

  41. Ethanol Sensitivity in ATP-Gated P2X Receptors Is Subunit Dependent

    Article • Alcoholism Clinical and Experimental Research, June 2002, Wiley

    Daryl L Davies

  42. Pressure-sensitive and -insensitive coupling in γ-aminobutyric acid a receptors

    Article • Psychopharmacology, October 2001, Springer Science + Business Media

    Daryl L Davies

  43. Direct Evidence for a Cause-Effect Link Between Ethanol Potentiation of GABAA Receptor Function and Intoxication From Hyperbaric Studies in C57, LS, and SS Mice

    Article • Alcoholism Clinical and Experimental Research, August 2001, Wiley

    Daryl L Davies

  44. Direct Evidence for a Cause-Effect Link Between Ethanol Potentiation of GABAA Receptor Function and Intoxication From Hyperbaric Studies in C57, LS, and SS Mice

    Article • Alcoholism Clinical and Experimental Research, August 2001, Wiley

    Daryl L Davies

  45. Ethanol Enhances GABAA Receptor Function in Short Sleep and Long Sleep Mouse Brain Membranes

    Article • Alcoholism Clinical and Experimental Research, March 2001, Wiley

    Daryl L Davies

  46. Ethanol Enhances GABAA Receptor Function in Short Sleep and Long Sleep Mouse Brain Membranes

    Article • Alcoholism Clinical and Experimental Research, March 2001, Wiley

    Daryl L Davies

  47. Effects of Posttraining Ethanol on an Appetitive Task

    Article • Neurobiology of Learning and Memory, January 2001, Elsevier

    Daryl L Davies

  48. In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol

    Article • Psychopharmacology, February 1999, Springer Science + Business Media

    Daryl L Davies

  49. Direct Antagonism of Ethanol??s Effects On GABAA Receptors by Increased Atmospheric Pressure

    Article • Alcoholism Clinical and Experimental Research, November 1998, Wiley

    Daryl L Davies

  50. Direct Antagonism of Ethanol's Effects On GABAA Receptors by Increased Atmospheric Pressure

    Article • Alcoholism Clinical and Experimental Research, November 1998, Wiley

    Daryl L Davies

  51. Low-Level Hyperbaric Exposure Antagonizes Locomotor Effects of Ethanol and n-Propanol But Not Morphine in C57BL Mice

    Article • Alcoholism Clinical and Experimental Research, June 1995, Wiley

    Daryl L Davies

  52. Low-Level Hyperbaric Antagonism of Ethanol's Anticonvulsant Property in C57BL/6J Mice

    Article • Alcoholism Clinical and Experimental Research, October 1994, Wiley

    Daryl L Davies