All Stories

  1. A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

    Article • Advanced Science, April 2026, Wiley

    Professor Yue Wang

  2. Direct RNA sequencing and signal alignment reveal RNA structure ensembles in a eukaryotic cell

    Article • Nature Chemical Biology, April 2026, Springer Science + Business Media

    Professor Yue Wang

  3. Candida auris vacuolar calcium pump mediates fluconazole efflux and resistance evolution

    Article • Nature Microbiology, February 2026, Springer Science + Business Media

    Professor Yue Wang

  4. Boronic acid derivatives inhibit Candida albicans growth by compromising energy metabolism

    Article • Journal of Advanced Research, July 2025, Elsevier

    Professor Yue Wang

  5. Macrophage-membrane-camouflaged nanoagents for precise bacterial clearance

    Article • The Innovation, July 2025, Elsevier

    Professor Yue Wang, Heng Dong

  6. Nanozymes: An emerging arsenal for the treatment of Candida albicans infection

    Article • Fundamental Research, May 2025, Elsevier

    Professor Yue Wang, Heng Dong

  7. Synthetic High‐Throughput Microarrays of Peptidoglycan Fragments as a Novel Sero‐Diagnostic Tool for Patient Antibody Profiling

    Article • Angewandte Chemie, February 2025, Wiley

    Professor Yue Wang

  8. The impact of the host microbiota on Candida albicans infection

    Article • Current Opinion in Microbiology, August 2024, Elsevier

    Professor Yue Wang

  9. Pathogenic fungi: Novel targets and theranostic strategies

    Article • Advanced Drug Delivery Reviews, July 2024, Elsevier

    Professor Yue Wang

  10. Genome‐wide profiling of piggyBac transposon insertion mutants reveals loss of the F1F0 ATPase complex causes fluconazole resistance in Candida glabrata

    Article • Molecular Microbiology, January 2024, Wiley

    Professor Yue Wang

  11. Nanorobots to Treat Candida albicans Infection

    Article • Research, January 2024, American Association for the Advancement of Science

    Professor Yue Wang

  12. The transcription factor Rpn4 activates its own transcription and induces efflux pump expression to confer fluconazole resistance in Candida auris

    Article • mBio, December 2023, ASM Journals

    Professor Yue Wang

  13. Cytochrome c regulates hyphal morphogenesis by interfering with cAMP-PKA signaling in Candida albicans

    Article • Cell Reports, December 2023, Elsevier

    Professor Yue Wang

  14. Water-Mediated In Situ Fabrication of CuI Nanoparticles on Flexible Cotton Fabrics as a Sustainable and Skin-Compatible Coating with Broad-Spectrum Antimicrobial Efficacy

    Article • ACS Applied Nano Materials, July 2023, American Chemical Society (ACS)

    Professor Yue Wang

  15. Impact of the host microbiota on fungal infections: New possibilities for intervention?

    Article • Advanced Drug Delivery Reviews, July 2023, Elsevier

    Professor Yue Wang

  16. Escherichia coli has robust regulatory mechanisms against elevated peptidoglycan cleavage by lytic transglycosylases

    Article • Journal of Biological Chemistry, April 2023, Elsevier

    Professor Yue Wang

  17. Comprehensive Interactome Analysis for the Sole Adenylyl Cyclase Cyr1 of Candida albicans

    Article • Microbiology Spectrum, December 2022, ASM Journals

    Professor Yue Wang

  18. Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans

    Article • The Cell Surface, December 2021, Elsevier

    Professor Yue Wang

  19. From Jekyll to Hyde: The Yeast–Hyphal Transition of Candida albicans

    Article • Pathogens, July 2021, MDPI AG

    Professor Yue Wang

  20. Author Correction: A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Professor Yue Wang

  21. LncRNA DINOR is a virulence factor and global regulator of stress responses in Candida auris

    Article • Nature Microbiology, June 2021, Springer Science + Business Media

    Professor Yue Wang

  22. A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection

    Article • Nature Communications, May 2021, Springer Science + Business Media

    Professor Yue Wang

  23. Orchestrated actin nucleation by the Candida albicans polarisome complex enables filamentous growth

    Article • Journal of Biological Chemistry, October 2020, Elsevier

    Professor Yue Wang

  24. Genome-wide piggyBac transposon-based mutagenesis and quantitative insertion-site analysis in haploid Candida species

    Article • Nature Protocols, July 2020, Springer Science + Business Media

    Professor Yue Wang

  25. BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

    Article • Journal of Immunology Research, June 2020, Wiley

    Professor Yue Wang

  26. Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole

    Article • Frontiers in Pharmacology, April 2020, Frontiers

    Professor Yue Wang

  27. Candida albicans Ubiquitin and Heat Shock Factor-Type Transcriptional Factors Are Involved in 2-Dodecenoic Acid-Mediated Inhibition of Hyphal Growth

    Article • Microorganisms, January 2020, MDPI AG

    Professor Yue Wang

  28. PP2A-Like Protein Phosphatase (Sit4) Regulatory Subunits, Sap155 and Sap190, Regulate Candida albicans’ Cell Growth, Morphogenesis, and Virulence

    Article • Frontiers in Microbiology, December 2019, Frontiers

    Professor Yue Wang

  29. Proteomics Analysis of Candida albicans dnm1 Haploid Mutant Unraveled the Association between Mitochondrial Fission and Antifungal Susceptibility

    Article • PROTEOMICS, December 2019, Wiley

    Professor Yue Wang

  30. The PP2A regulatory subunits, Cdc55 and Rts1, play distinct roles in Candida albicans’ growth, morphogenesis, and virulence

    Article • Fungal Genetics and Biology, October 2019, Elsevier

    Professor Yue Wang

  31. Elevation of cell wall chitin via Ca2+–calcineurin‐mediated PKC signaling pathway maintains the viability of Candida albicans in the absence of β‐1,6‐glucan synthesis

    Article • Molecular Microbiology, July 2019, Wiley

    Professor Yue Wang

  32. Dok3–protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity

    Article • Journal of Clinical Investigation, June 2019, American Society for Clinical Investigation

    Professor Yue Wang

  33. Phosphatidate phosphatase Pah1 has a role in the hyphal growth and virulence of Candida albicans

    Article • Fungal Genetics and Biology, March 2019, Elsevier

    Professor Yue Wang

  34. Author Correction: Candida albicans gains azole resistance by altering sphingolipid composition

    Article • Nature Communications, January 2019, Springer Science + Business Media

    Professor Yue Wang

  35. Blocking β‐1,6‐glucan synthesis by deleting KRE6 and SKN1 attenuates the virulence of Candida albicans

    Article • Molecular Microbiology, January 2019, Wiley

    Professor Yue Wang

  36. Multiple roles and diverse regulation of the Ras/cAMP/protein kinase A pathway in Candida albicans

    Article • Molecular Microbiology, November 2018, Wiley

    Professor Yue Wang

  37. Candida albicans gains azole resistance by altering sphingolipid composition

    Article • Nature Communications, October 2018, Springer Science + Business Media

    Professor Yue Wang

  38. G1 and S phase arrest in Candida albicans induces filamentous growth via distinct mechanisms

    Article • Molecular Microbiology, October 2018, Wiley

    Professor Yue Wang

  39. Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent

    Article • Frontiers in Cellular and Infection Microbiology, June 2018, Frontiers

    Professor Yue Wang

  40. Maize Transposable Elements Ac/Ds as Insertion Mutagenesis Tools in Candida albicans

    Article • G3 Genes Genomes Genetics, April 2018, Oxford University Press (OUP)

    Professor Yue Wang

  41. Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes

    Article • Nature Communications, March 2018, Springer Science + Business Media

    Professor Yue Wang

  42. Sac7 and Rho1 regulate the white-to-opaque switching in Candida albicans

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Professor Yue Wang

  43. Candida albicans possess a highly versatile and dynamic high‐affinity iron transport system important for its commensal‐pathogenic lifestyle

    Article • Molecular Microbiology, November 2017, Wiley

    Professor Yue Wang

  44. A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

    Article • Nature Microbiology, October 2017, Springer Science + Business Media

    Professor Yue Wang

  45. Candida Biofilms

    Article • July 2017, Taylor & Francis

    Professor Yue Wang

  46. Characterization of Pph3-mediated dephosphorylation of Rad53 during methyl methanesulfonate-induced DNA damage repair in Candida albicans

    Article • Biochemical Journal, March 2017, Portland Press Ltd.

    Professor Yue Wang

  47. Comparative Ploidy Proteomics of Candida albicans Biofilms Unraveled the Role of the AHP1 Gene in the Biofilm Persistence Against Amphotericin B

    Article • Molecular & Cellular Proteomics, November 2016, Elsevier

    Professor Yue Wang

  48. Sds22 participates in Glc7 mediated Rad53 dephosphorylation in MMS-induced DNA damage in Candida albicans

    Article • Fungal Genetics and Biology, August 2016, Elsevier

    Professor Yue Wang

  49. The Nim1 kinase Gin4 has distinct domains crucial for septin assembly, phospholipid binding and mitotic exit

    Article • Journal of Cell Science, July 2016, The Company of Biologists

    Professor Yue Wang

  50. Tpd3-Pph21 phosphatase plays a direct role in Sep7 dephosphorylation inCandida albicans

    Article • Molecular Microbiology, April 2016, Wiley

    Professor Yue Wang

  51. CDK phosphorylates the polarisome scaffold Spa2 to maintain its localization at the site of cell growth

    Article • Molecular Microbiology, April 2016, Wiley

    Professor Yue Wang

  52. Hgc1-Cdc28–how much does a single protein kinase do in the regulation of hyphal development in Candida albicans?

    Article • The Journal of Microbiology, February 2016, The Microbiological Society of Korea

    Professor Yue Wang

  53. MIG1Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids

    Article • Eukaryotic Cell, August 2015, ASM Journals

    Professor Yue Wang

  54. The mitochondrial protein Mcu1 plays important roles in carbon source utilization, filamentation, and virulence in Candida albicans

    Article • Fungal Genetics and Biology, August 2015, Elsevier

    Professor Yue Wang

  55. New “haploid biofilm model” unravels IRA2 as a novel regulator of Candida albicans biofilm formation

    Article • Scientific Reports, July 2015, Springer Science + Business Media

    Professor Yue Wang

  56. Cell Cycle-Independent Phospho-Regulation of Fkh2 during Hyphal Growth Regulates Candida albicans Pathogenesis

    Article • PLoS Pathogens, January 2015, PLOS

    Dr Julian Naglik, Professor Yue Wang

  57. Bimodal Influence of Vitamin D in Host Response to SystemicCandidaInfection—Vitamin D Dose Matters

    Article • The Journal of Infectious Diseases, January 2015, Oxford University Press (OUP)

    Professor Yue Wang

  58. Novel Mechanism Coupling Cyclic AMP-Protein Kinase A Signaling and Golgi Trafficking via Gyp1 Phosphorylation in Polarized Growth

    Article • Eukaryotic Cell, October 2014, ASM Journals

    Professor Yue Wang, Dr Zhen-Xing Huang

  59. Regulation of Rfa2 phosphorylation in response to genotoxic stress inCandida albicans

    Article • Molecular Microbiology, August 2014, Wiley

    Professor Yue Wang

  60. Phosphoregulation of Nap1 Plays a Role in Septin Ring Dynamics and Morphogenesis in Candida albicans

    Article • mBio, February 2014, ASM Journals

    Professor Yue Wang, Dr Zhen-Xing Huang

  61. One-step targeted gene deletion in Candida albicans haploids

    Article • Nature Protocols, January 2014, Springer Science + Business Media

    Professor Yue Wang

  62. Fungal Adenylyl Cyclase Acts As a Signal Sensor and Integrator and Plays a Central Role in Interaction with Bacteria

    Article • PLoS Pathogens, October 2013, PLOS

    Professor Yue Wang

  63. The ‘obligate diploid’ Candida albicans forms mating-competent haploids

    Article • Nature, January 2013, Springer Science + Business Media

    Professor Yue Wang

  64. Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans

    Article • Biochemical Journal, January 2013, Portland Press Ltd.

    Professor Yue Wang

  65. Cdc28–Cln3 phosphorylation of Sla1 regulates actin patch dynamics in different modes of fungal growth

    Article • Molecular Biology of the Cell, September 2012, American Society for Cell Biology (ASCB)

    Professor Yue Wang

  66. Shp1, a regulator of protein phosphatase 1 Glc7, has important roles in cell morphogenesis, cell cycle progression and DNA damage response in Candida albicans

    Article • Fungal Genetics and Biology, June 2012, Elsevier

    Professor Yue Wang

  67. Pph3 Dephosphorylation of Rad53 Is Required for Cell Recovery from MMS-Induced DNA Damage in Candida albicans

    Article • PLOS One, May 2012, PLOS

    Professor Yue Wang

  68. CDK Regulates Septin organization through Cell-cycle-dependent Phosphorylation of the Nim1-related Kinase Gin4

    Article • Journal of Cell Science, January 2012, The Company of Biologists

    Professor Yue Wang

  69. Characterization of a hyperactive Cyr1 mutant reveals new regulatory mechanisms for cellular cAMP levels in Candida albicans

    Article • Molecular Microbiology, October 2011, Wiley

    Professor Yue Wang

  70. Protein Phosphatase Pph3 and Its Regulatory Subunit Psy2 Regulate Rad53 Dephosphorylation and Cell Morphogenesis during Recovery from DNA Damage in Candida albicans

    Article • Eukaryotic Cell, September 2011, ASM Journals

    Professor Yue Wang

  71. CDK-dependent phosphorylation of Mob2 is essential for hyphal development inCandida albicans

    Article • Molecular Biology of the Cell, July 2011, American Society for Cell Biology (ASCB)

    Professor Yue Wang

  72. CO2 Acts as a Signalling Molecule in Populations of the Fungal Pathogen Candida albicans

    Article • PLoS Pathogens, November 2010, PLOS

    Dr Rebecca A Hall, Professor Yue Wang

  73. Linking cellular actin status with cAMP signaling inCandida albicans

    Article • Virulence, May 2010, Taylor & Francis

    Professor Yue Wang

  74. Candida albicans Cyr1, Cap1 and G‐actin form a sensor/effector apparatus for activating cAMP synthesis in hyphal growth

    Article • Molecular Microbiology, January 2010, Wiley

    Professor Yue Wang

  75. CDKs and the yeast-hyphal decision

    Article • Current Opinion in Microbiology, December 2009, Elsevier

    Professor Yue Wang

  76. Ras1 and Ras2 play antagonistic roles in regulating cellular cAMP level, stationary‐phase entry and stress response in Candida albicans

    Article • Molecular Microbiology, November 2009, Wiley

    Professor Yue Wang

  77. The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in Candida albicans

    Article • The EMBO Journal, October 2008, Springer Science + Business Media

    Professor Yue Wang

  78. CaSfl1 plays a dual role in transcriptional regulation in Candida albicans

    Article • Science Bulletin, August 2008, Elsevier

    Professor Yue Wang

  79. Use of multiple methods for genotyping Fusariumduring an outbreak of contact lens associated fungal keratitis in Singapore

    Article • BMC Infectious Diseases, July 2008, Springer Science + Business Media

    Professor Yue Wang

  80. Bacterial Peptidoglycan Triggers Candida albicans Hyphal Growth by Directly Activating the Adenylyl Cyclase Cyr1p

    Article • Cell Host & Microbe, July 2008, Elsevier

    Professor Yue Wang

  81. Role of CaECM25 in cell morphogenesis, cell growth and virulence in Candida albicans

    Article • Science in China Series C Life Sciences, March 2008, Springer Science + Business Media

    Professor Yue Wang

  82. Cyclin-Dependent Kinases Control Septin Phosphorylation in Candida albicans Hyphal Development

    Article • Developmental Cell, September 2007, Elsevier

    Professor Yue Wang

  83. Phosphorylation of Rga2, a Cdc42 GAP, by CDK/Hgc1 is crucial for Candida albicans hyphal growth

    Article • The EMBO Journal, August 2007, Springer Science + Business Media

    Professor Yue Wang

  84. Candida albicanshyphal morphogenesis occurs in Sec3p-independent and Sec3p-dependent phases separated by septin ring formation

    Article • Journal of Cell Science, June 2007, The Company of Biologists

    Professor Yue Wang

  85. Critical Role of DNA Checkpoints in Mediating Genotoxic-Stress–induced Filamentous Growth inCandida albicans

    Article • Molecular Biology of the Cell, March 2007, American Society for Cell Biology (ASCB)

    Professor Yue Wang

  86. Polarity control in Candida albicans morphogenesis and virulence

    Article • March 2007, Elsevier

    Professor Yue Wang

  87. Predominance ofCandidatropicalisbloodstream infections in a Singapore teaching hospital

    Article • Medical Mycology, January 2007, Oxford University Press (OUP)

    Professor Yue Wang

  88. The F‐box protein Grr1 regulates the stability of Ccn1, Cln3 and Hof1 and cell morphogenesis in Candida albicans

    Article • Molecular Microbiology, August 2006, Wiley

    Professor Yue Wang

  89. ACE2 orthologues in non-mammalian vertebrates (Danio, Gallus, Fugu, Tetraodon and Xenopus)

    Article • Gene, August 2006, Elsevier

    Professor Yue Wang

  90. RA domain‐mediated interaction of Cdc35 with Ras1 is essential for increasing cellular cAMP level for Candida albicans hyphal development

    Article • Molecular Microbiology, June 2006, Wiley

    Professor Yue Wang

  91. MNN5 Encodes an Iron-Regulated α-1,2-Mannosyltransferase Important for Protein Glycosylation, Cell Wall Integrity, Morphogenesis, and Virulence in Candida albicans

    Article • Eukaryotic Cell, February 2006, ASM Journals

    Professor Yue Wang

  92. Identification and functional characterization of a novel Candida albicans gene CaMNN5 that suppresses the iron-dependent growth defect of Saccharomyces cerevisiae aft1Δ mutant

    Article • Biochemical Journal, June 2005, Portland Press Ltd.

    Professor Yue Wang

  93. The formin family protein CaBni1p has a role in cell polarity control during both yeast and hyphal growth inCandida albicans

    Article • Journal of Cell Science, June 2005, The Company of Biologists

    Professor Yue Wang

  94. Participation of the ubiquitin-proteasome pathway in rat oocyte activation

    Article • Zygote, February 2005, Cambridge University Press

    Professor Yue Wang

  95. Hgc1, a novel hypha-specific G1 cyclin-related protein regulates Candida albicans hyphal morphogenesis

    Article • The EMBO Journal, April 2004, Springer Science + Business Media

    Professor Yue Wang

  96. CaSPA2is important for polarity establishment and maintenance inCandida albicans

    Article • Molecular Microbiology, August 2003, Wiley

    Professor Yue Wang

  97. Prevalence of Candida Species, Including Candida dubliniensis, in Singapore

    Article • Journal of Clinical Microbiology, January 2003, ASM Journals

    Professor Yue Wang

  98. Characterization of iron-binding motifs in Candida albicans high-affinity iron permease CaFtr1p by site-directed mutagenesis

    Article • Biochemical Journal, December 2002, Portland Press Ltd.

    Professor Yue Wang

  99. Characterization and Functional Analysis of the Siderophore-Iron Transporter CaArn1p in Candida albicans

    Article • Journal of Biological Chemistry, August 2002, Elsevier

    Professor Yue Wang

  100. Spindle assembly checkpoint component CaMad2p is indispensable for Candida albicans survival and virulence in mice

    Article • Molecular Microbiology, June 2002, Wiley

    Professor Yue Wang

  101. Isolation of Streptonigrin and Its Novel Derivative from Micromonospora as Inducing Agents of p53-Dependent Cell Apoptosis

    Article • Journal of Natural Products, April 2002, American Chemical Society (ACS)

    Professor Yue Wang

  102. Candida dubliniensis Infection, Singapore

    Article • Emerging Infectious Diseases, April 2002, Centers for Disease Control and Prevention (CDC)

    Professor Yue Wang

  103. Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals

    Article • Proceedings of the National Academy of Sciences, February 2002, Proceedings of the National Academy of Sciences

    Professor Yue Wang

  104. Isolation of a Novel Protein Tyrosine Phosphatase Inhibitor, 2-Methyl-Fervenulone, and Its Precursors from Streptomyces

    Article • Journal of Natural Products, November 2000, American Chemical Society (ACS)

    Professor Yue Wang

  105. A High-Affinity Iron Permease Essential for Candida albicans Virulence

    Article • Science, May 2000, American Association for the Advancement of Science

    Professor Yue Wang

  106. Investigation of actinomycete diversity in the tropical rainforests of Singapore

    Article • Journal of Industrial Microbiology & Biotechnology, September 1999, Oxford University Press (OUP)

    Professor Yue Wang

  107. Molecular cloning and comparative sequence analyses of rRNA operons in Streptomyces nodosus ATCC 14899

    Article • Gene, May 1999, Elsevier

    Professor Yue Wang

  108. Kinetic Analysis of two Closely Related Receptor‐Like Protein‐Tyrosine‐Phosphatases, PTPα and PTPε

    Article • FEBS Journal, May 1997, Wiley

    Professor Yue Wang

  109. Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

    Article • Nature, September 1992, Springer Science + Business Media

    Professor Yue Wang

  110. Interactions between structure transitions in a torsionally constrained DNA

    Article • Biochemical and Biophysical Research Communications, February 1989, Elsevier

    Professor Yue Wang

  111. Flanking AT-rich sequences may lower the activation energy of cruciform extrusion in supercoiled DNA

    Article • Biochemical and Biophysical Research Communications, January 1989, Elsevier

    Professor Yue Wang

  112. Site-specific cleavage of supercoiled DNA by ascorbate/Cu(II)

    Article • Nucleic Acids Research, January 1989, Oxford University Press (OUP)

    Professor Yue Wang

  113. Mapping structurally perturbed sites in DNA by replication arrest and run-off replication

    Article • Biochemical and Biophysical Research Communications, August 1987, Elsevier

    Professor Yue Wang