All Stories

  1. Targeted isolation of previously undescribed fortunefuroic acid-type triterpenoids from Keteleeria pubescens using 1H NMR/LC-PDA-MS and assessment of ACL Inhibition
  2. Alcimaphenols A and B, oligomeric denudaquinols with antiproliferative and antimigratory activities from the endangered plant Alcimandra cathcartii
  3. Platanosides, a Promising Class of Plant-Derived Antibiotics, Are Effective against a Suite of Clinically Derived MDR and Drug-Sensitive Staph and Strep spp.
  4. Phytochemical diversity and therapeutic potential of the Polyalthia genus: a comprehensive review
  5. Therapeutic Applications of Ficus deltoidea: An Integrative Review of Its Pharmacological Properties
  6. Docking-Based Virtual Screening of Bisbenzylisoquinoline Derivatives from <i>Stephania</i> Genus Against Hepatocellular Carcinoma
  7. Biosynthesis of silver nanoparticles using mobe (Artocarpus lakoocha Roxb) leaf aqueous extracts and their potential as antioxidant and antibacterial agents
  8. Phytochemical and biological studies on rare and endangered plants endemic to China. Part XLIX. Terpenoids and phenylpropanoid-substituted flavan-3-ols from the leaves of Camellia petelotii (golden-flower tea) and their bioactivities
  9. Phytochemical and biological studies on rare and endangered plants endemic to China. Part XLVII. Sesquiterpene lactones from the leaves of Michelia opipara and their anti-inflammation effects
  10. An evidence-based review of the ethnomedicinal, phytochemical, and pharmacological properties of Typhonium flagelliforme
  11. In silico approach and in vitro study of fangchinoline-induced apoptosis and reactive oxygen species production in HER2-overexpressing breast cancer cells
  12. Anticancer effects of fangchinoline in 4T1 breast cancer cells: in vitro and in silico analysis of TGF-β1 and mTOR pathways
  13. Phytochemistry and Pharmacological Potential of the Genus Prismatomeris
  14. Aleutianamine B, A Novel Chiral Sulfoxide Isolated from Latrunculia spp. and Generated via Semi-Synthesis, Exhibits Selectivity for Ovarian Cancer Cells
  15. Biological Characterization of Mupirocin–KGF Hydrogel and Its Regenerative Potential in Human Fibroblast-Mediated Wound Healing
  16. Tsugaforrestolide, an Anti‐Inflammatory Bisabolane‐Type Sesquiterpene Lactone From the Vulnerable Conifer Tsuga forrestii
  17. Exploring the Multitarget Therapeutic Potential of Mangostin Derivatives
  18. Diterpene-phenylpropanoid hybrids and structurally diverse diterpenoid monomers from the endangered conifer Podocarpus annamiensis and their bioactivities
  19. Structurally diverse terpenoids from Pseudotsuga brevifolia and their inhibitory effects against ACL and ACC1 enzymes
  20. Chemical Synthesis and Enzymatic Modification of Mangostins: A Comprehensive Review on Structural Modifications for Drug Discovery
  21. Bletistrosides M-X, Anti-Alzheimer’s Disease Compounds from the Tubers of Bletilla striata
  22. Phytochemical and biological studies on rare and endangered plants endemic to China. Part XLIV. Integrated NMR/EI-MS/LC-PDA-ESIMS approach for dereplication and targeted isolation of fortunefuroic acids from Keteleeria fortunei across diverse geographi...
  23. Utilization of Artocarpus altilis leaf extract for silver nanoparticle synthesis: Comparative antioxidant and antibacterial evaluation with water extract
  24. The Malaysian Natural Product Database: A Structure Repository of Malaysia's Natural Compounds
  25. Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase - A systematic review
  26. Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers
  27. Antimalarial Drug Discovery from Natural and Synthetic Sources
  28. Benzofurans and dibenzofurans from galls on twigs of the endangered Chinese endemic tree Parrotia subaequalis and their inhibitory properties against Staphylococcus aureus and ATP-citrate lyase
  29. PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF EXTRACT AND FRACTION OF Z. Acanthopodium DC. FRUITS
  30. Spiroamentotaxols A–D: unprecedented 6/6/6/5/6/6/6/6 spiro-octacyclic bis-diterpene heterodimers from the endangered conifer Amentotaxus yunnanensis and their bioactivities
  31. Bis-Iridoid Glycosides and Triterpenoids from Kolkwitzia amabilis and Their Potential as Inhibitors of ACC1 and ACL
  32. High-value flavonoids with potential anti-inflammatory benefits from Platanus × acerifolia Willd leaves: Turning waste into treasure
  33. Major specialized natural products from the endangered plant Heptacodium miconioides, potential medicinal uses and insights into its longstanding unresolved systematic classification
  34. Phytochemical diversity and therapeutic potential of the Boesenbergia genus: a comprehensive review
  35. Harnessing Natural Resources for Advancements in Dengue Virus Treatment
  36. Cannabinoid-Inspired Inhibitors of the SARS-CoV-2 Coronavirus 2′-O-Methyltransferase (2′-O-MTase) Non-Structural Protein (Nsp10–16)
  37. Fortunefuroic Acid J from Keteleeria Hainanensis and its Dual Inhibitory Effects on ATP‐Citrate Lyase and Acetyl‐CoA Carboxylase.
  38. Computationally-Assisted Discovery and Assignment of a New Class of 6/6/5/5 Fused-Ring Diterpene Acting as Pregnane X Receptor Ligands from Isodon serra
  39. PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF METHANOL EXTRACT OF ZANTHOXYLUM ACANTHOPODIUM DC. FRUITS USING CUPRAC METHODS
  40. Targeting sine oculis homeoprotein 1 (SIX1): A review of oncogenic roles and potential natural product therapeutics
  41. Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8‐DNA interactions and effectively inhibits prostate tumor growth in mice
  42. A New Oxoaporphine and Liriodenine's Anti-Neuroblastoma Potential from the Roots of Polyalthia bullata King
  43. Platanosides from Platanus × acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
  44. Informatics and Computational Approaches for the Discovery and Optimization of Natural Product-Inspired Inhibitors of the SARS-CoV-2 2′-O-Methyltransferase
  45. Computationally-Assisted Discovery and computational NMR Assignment of a Highly-binding PXR Natural Diterpenoids
  46. Boesenbergia stenophylla-Derived Stenophyllol B Exerts Antiproliferative and Oxidative Stress Responses in Triple-Negative Breast Cancer Cells with Few Side Effects in Normal Cells
  47. In-Silico Approaches for the Screening and Discovery of Broad-Spectrum Marine Natural Product Antiviral Agents Against Coronaviruses
  48. Glabraquinone A and B, new bis anthraquinones from Prismatomeris glabra (Korth.) Valeton
  49. Ultrasound-Assisted Extraction of β-Asarone from Sweet Flag (Acorus calamus) Rhizome
  50. Manzamine-A Alters In Vitro Calvarial Osteoblast Function
  51. Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice
  52. Facile Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers
  53. Chemical Constituents and Anti-Neuroblastoma Activity from Boesenbergia stenophylla
  54. Structure and Antimicrobial Activity of Rare Lactone Lipids from the Sooty Mold (Scorias spongiosa)
  55. Recent advances and limitations in the application of kahalalides for the control of cancer
  56. Ultrasound-assisted encapsulation of Pandan (Pandanus amaryllifolius) extract
  57. Contemporary Approaches to the Discovery and Development of Broad-Spectrum Natural Product Prototypes for the Control of Coronaviruses
  58. Computational View of β-Asarone–Human Serum Albumin Interaction
  59. RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study
  60. Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
  61. Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
  62. Stenophyllols A-C, new compounds from Boesenbergia stenophylla
  63. The Marine Natural Product Manzamine A Inhibits Cervical Cancer by Targeting the SIX1 Protein
  64. A Novel Liquid Chromatography Tandem Mass Spectrometry Technique using Multi-Period-Multi-Experiment of MRM-EPI-MRM3 with Library Matching for Simultaneous Determination of Amphetamine Type Stimulants Related Drugs in Whole Blood, Urine and Dried Blood...
  65. Detection of Five Mycotoxins in Different Food Matrices in the Malaysian Market by Using Validated Liquid Chromatography Electrospray Ionization Triple Quadrupole Mass Spectrometry
  66. Determination of Mycotoxins Using Hollow Fiber Dispersive Liquid–Liquid–Microextraction (HF-DLLME) Prior to High-Performance Liquid Chromatography – Tandem Mass Spectrometry (HPLC - MS/MS)
  67. High-throughput flow injection analysis-MRM3 (FIA-MRM3) spectrometry for alternative fast screening of the isomeric methamphetamine and phentermine in blood for forensic toxicology cases in Malaysia
  68. Isolation and Photophysical Properties of Di- and Tri-substituted Natural Anthraquinones from Malaysian Morinda citrifolia
  69. A New Cyclopentylidene and Other Chemical Constituents from Malaysian Crotalaria pallida
  70. Efficiency of Hollow Fiber Liquid-Phase Microextraction Chromatography Methods in the Separation of Organic Compounds: A Review
  71. A new flavone from Malaysia Borneo Marsdenia tinctoria
  72. A new oxolane fromEnterobacter cloacae
  73. The Last and Next Decades of the Asian Core Program on Cutting‐Edge Organic Chemistry in Asia
  74. A new oxathiolane from Enterobacter cloacae
  75. A Coumarin-Based Fluorescent Probe as a Central Nervous System Disease Biomarker
  76. N-acyl Homoserine Lactone-Producing Pseudomonas putida Strain T2-2 from Human Tongue Surface
  77. Terminal Spin Labeling of a High-mannose-type Oligosaccharide for Quantitative NMR Analysis of Its Dynamic Conformation
  78. Is chronic levodopa therapy associated with distal symmetric polyneuropathy in Parkinson's disease?
  79. Phytochemical Studies of Malaysian Crotalaria Mucronata
  80. Characterization of Quorum Sensing and Quorum Quenching Soil Bacteria Isolated from Malaysian Tropical Montane Forest
  81. Coexistence of quorum-quenching and quorum-sensing in tropical marine Pseudomonas aeruginosa strain MW3A
  82. Grandilodines A−C, Biologically Active Indole Alkaloids fromKopsia grandifolia
  83. Strychnan and Secoangustilobine A Type Alkaloids fromAlstonia spatulata.Revision of the C-20 Configuration of Scholaricine
  84. Unusual indole alkaloid–pyrrole, –pyrone, and –carbamic acid adducts from Alstonia angustifolia
  85. Structure, biological activity, and a biomimetic partial synthesis of the lirofolines, novel pentacylic indole alkaloids from Tabernaemontana
  86. Structure−Activity Relationship and Mechanism of Action Studies of Manzamine Analogues for the Control of Neuroinflammation and Cerebral Infections
  87. ChemInform Abstract: Bisindole Alkaloids
  88. ChemInform Abstract: The Alkaloids of the Mersinine Group: A New Subclass of the Monoterpenoid Indole Alkaloids from Kopsia.
  89. The alkaloids of the mersinine group: a new subclass of the monoterpenoid indole alkaloids from Kopsia
  90. An Improved Pictet-Spengler Condensation: A Convenient Synthetic Route to Bioactive Manzamine Derivatives
  91. Chapter 4 Bisindole Alkaloids
  92. Venalstonine and Dioxokopsan Derivatives from Kopsia fruticosa.
  93. Mersicarpine, an Unusual Tetracyclic Dihydroindole Alkaloid Incorporating a Seven-Membered Imine Ring.
  94. Kopsifolines A-F: A New Structural Class of Monoterpenoid Indole Alkaloids from Kopsia.
  95. Unusual Spirocyclic Macroline Alkaloids, Nitrogenous Derivatives, and a Cytotoxic Bisindole from Alstonia.
  96. Angustilodine, an Unusual Pentacyclic Indole Alkaloid from Alstonia.
  97. Mersicarpine, an unusual tetracyclic dihydroindole alkaloid incorporating a seven-membered imine ring
  98. Venalstonine and dioxokopsan derivatives from Kopsia fruticosa
  99. Biologically Active Ibogan and Vallesamine Derivatives fromTabernaemontana divaricata
  100. Kopsifolines A–F: a New Structural Class of Monoterpenoid Indole Alkaloids fromKopsia
  101. New Indole Alkaloids fromAlstonia macrophylla
  102. Unusual spirocyclic macroline alkaloids, nitrogenous derivatives, and a cytotoxic bisindole from Alstonia
  103. Alkaloids from Alstonia angustifolia
  104. Angustilodine, an Unusual Pentacyclic Indole Alkaloid fromAlstonia
  105. Macrodasine A, a novel macroline derivative incorporating fused spirocyclic tetrahydrofuran rings containing a spiroacetal moiety
  106. Kopsifolines A, B, and C, indole alkaloids with a novel hexacyclic carbon skeleton from Kopsia
  107. Novel Macroline Oxindoles from a Malayan Alstonia
  108. Indole and monoterpene alkaloids from the leaves of Kopsia dasyrachis
  109. Alkaloids from the stem-bark of Alstonia macrophylla
  110. Structure and biomimetic, electrochemically-mediated semisynthesis of the novel pentacyclic indole danuphylline
  111. Danuphylline, a novel pentacyclic indole from Kopsia
  112. Manzamine Alkaloids