All Stories

  1. Phosphorylation of RecA at the Loop 1 region modulates its activity in response to DNA damage

    Article • International Journal of Biological Macromolecules, December 2025, Elsevier

    Dr Ye Zhao

  2. Distinct functional heterogeneity of TP53 R175 mutations in platinum-resistant ovarian cancer: unveiling molecular mechanisms and therapeutic targets

    Article • Cell Death and Disease, November 2025, Springer Science + Business Media

    Dr Ye Zhao

  3. An activator regulates the DNA damage response and anti-phage defense networks in Moraxellaceae

    Article • Nucleic Acids Research, August 2025, Oxford University Press (OUP)

    Dr Ye Zhao

  4. The Construction of an Extreme Radiation-Resistant Perchlorate-Reducing Bacterium Using Deinococcus deserti Promoters

    Article • International Journal of Molecular Sciences, October 2024, MDPI AG

    Dr Ye Zhao

  5. cAMP-independent DNA binding of the CRP family protein DdrI from Deinococcus radiodurans

    Article • mBio, July 2024, ASM Journals

    Dr Ye Zhao

  6. Precise CRISPR/Cpf1 genome editing system in the Deinococcus radiodurans with superior DNA repair mechanisms

    Article • Microbiological Research, July 2024, Elsevier

    Dr Ye Zhao

  7. POLM variant G312R promotes ovarian tumorigenesis through genomic instability and COL11A1-NF-κB axis

    Article • AJP Cell Physiology, July 2024, American Physiological Society

    Dr Ye Zhao

  8. Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling

    Article • Advanced Science, April 2024, Wiley

    Dr Ye Zhao

  9. Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer

    Article • Cellular and Molecular Life Sciences, March 2024, Springer Science + Business Media

    Dr Ye Zhao

  10. The Deinococcus protease PprI senses DNA damage by directly interacting with single-stranded DNA

    Article • Nature Communications, February 2024, Springer Science + Business Media

    Dr Ye Zhao

  11. Characterization of a Novel N4-Methylcytosine Restriction-Modification System in Deinococcus radiodurans

    Article • International Journal of Molecular Sciences, January 2024, MDPI AG

    Dr Ye Zhao

  12. MoaE Is Involved in Response to Oxidative Stress in Deinococcus radiodurans

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Dr Ye Zhao

  13. Probing the sORF-Encoded Peptides of Deinococcus radiodurans in Response to Extreme Stress

    Article • Molecular & Cellular Proteomics, November 2022, Elsevier

    Dr Ye Zhao

  14. Phosphorylation Regulation of a Histone-like HU Protein from Deinococcus radiodurans

    Article • Protein & Peptide Letters, October 2022, Bentham Science Publishers

    Dr Ye Zhao

  15. Mechanisms of helicase activated DNA end resection in bacteria

    Article • Structure, September 2022, Elsevier

    Dr Ye Zhao

  16. Structural and Functional Characterization of the Holliday Junction Resolvase RuvC from Deinococcus radiodurans

    Article • Microorganisms, June 2022, MDPI AG

    Dr Ye Zhao

  17. DRJAMM Is Involved in the Oxidative Resistance in Deinococcus radiodurans

    Article • Frontiers in Microbiology, January 2022, Frontiers

    Dr Ye Zhao

  18. One‐Step Enzymatic Labeling Reveals a Critical Role of O‐GlcNAcylation in Cell‐Cycle Progression and DNA Damage Response

    Article • Angewandte Chemie, November 2021, Wiley

    Dr Ye Zhao

  19. Mechanism of genome instability mediated by human DNA polymerase mu misincorporation

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Dr Ye Zhao

  20. Biochemical characterization of a unique DNA polymerase A from the extreme radioresistant organism Deinococcus radiodurans

    Article • Biochimie, June 2021, Elsevier

    Dr Ye Zhao

  21. MazEF Toxin-Antitoxin System-Mediated DNA Damage Stress Response in Deinococcus radiodurans

    Article • Frontiers in Genetics, February 2021, Frontiers

    Dr Ye Zhao

  22. Late embryogenesis abundant group3 protein (DrLEA3) is involved in antioxidation in the extremophilic bacterium Deinococcus radiodurans

    Article • Microbiological Research, November 2020, Elsevier

    Dr Ye Zhao

  23. Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability

    Article • AJP Cell Physiology, October 2020, American Physiological Society

    Dr Ye Zhao

  24. Structural and Functional Characterization of a Unique AP Endonuclease From Deinococcus radiodurans

    Article • Frontiers in Microbiology, June 2020, Frontiers

    Dr Ye Zhao

  25. <p>Functionalized Gold and Silver Bimetallic Nanoparticles Using <em>Deinococcus radiodurans</em> Protein Extract Mediate Degradation of Toxic Dye Malachite Green</p>

    Article • International Journal of Nanomedicine, March 2020, Taylor & Francis

    Dr Ye Zhao

  26. Structural features and functional implications of proteins enabling the robustness of Deinococcus radiodurans

    Article • Computational and Structural Biotechnology Journal, January 2020, Elsevier

    Dr Ye Zhao

  27. Succinylome Analysis Reveals the Involvement of Lysine Succinylation in the Extreme Resistance of Deinococcus radiodurans

    Article • PROTEOMICS, September 2019, Wiley

    Dr Ye Zhao

  28. N4-Cytosine DNA Methylation Is Involved in the Maintenance of Genomic Stability in Deinococcus radiodurans

    Article • Frontiers in Microbiology, August 2019, Frontiers

    Dr Ye Zhao

  29. Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO

    Article • Nucleic Acids Research, August 2019, Oxford University Press (OUP)

    Dr Ye Zhao

  30. Structural basis of 5′ flap recognition and protein–protein interactions of human flap endonuclease 1

    Article • Nucleic Acids Research, October 2018, Oxford University Press (OUP)

    Dr Ye Zhao

  31. SUMO-1 modification of FEN1 facilitates its interaction with Rad9–Rad1–Hus1 to counteract DNA replication stress

    Article • Journal of Molecular Cell Biology, October 2018, Oxford University Press (OUP)

    Dr Ye Zhao

  32. Deinococcus radiodurans DR1088 is a novel RecF-interacting protein that stimulates single-stranded DNA annealing

    Article • Molecular Microbiology, October 2017, Wiley

    Dr Ye Zhao

  33. Characterization and role of a 2′,3′-cyclic phosphodiesterase from Deinococcus radiodurans

    Article • Biotechnology Letters, May 2017, Springer Science + Business Media

    Dr Ye Zhao

  34. Crystal structure of the RNA 2′,3′-cyclic phosphodiesterase fromDeinococcus radiodurans

    Article • Acta Crystallographica Section F Structural Biology Communications, April 2017, International Union of Crystallography

    Dr Ye Zhao

  35. An Improved Method for Identifying Specific DNA-Protein-Binding Sites In Vitro

    Article • Molecular Biotechnology, January 2017, Springer Science + Business Media

    Dr Ye Zhao

  36. Lysine Acetylation and Succinylation in HeLa Cells and their Essential Roles in Response to UV-induced Stress

    Article • Scientific Reports, July 2016, Nature

    Dr Ye Zhao

  37. The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer

    Article • Scientific Reports, May 2016, Nature

    Dr Ye Zhao

  38. Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans

    Article • PLOS One, May 2016, PLOS

    Dr Ye Zhao

  39. Structural basis for DNA 5´-end resection by RecJ

    Article • eLife, April 2016, eLife

    Dr Ye Zhao

  40. Proteomic insights into the functional basis for the response regulator DrRRA ofDeinococcus radiodurans

    Article • International Journal of Radiation Biology, March 2016, Taylor & Francis

    Dr Ye Zhao

  41. DqsIR quorum sensing-mediated gene regulation of the extremophilic bacteriumDeinococcus radioduransin response to oxidative stress

    Article • Molecular Microbiology, February 2016, Wiley

    Dr Ye Zhao

  42. A Novel C-Terminal Domain of RecJ is Critical for Interaction with HerA in Deinococcus radiodurans

    Article • Frontiers in Microbiology, November 2015, Frontiers

    Dr Ye Zhao

  43. Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J

    Article • Nucleic Acids Research, May 2015, Oxford University Press (OUP)

    Dr Ye Zhao

  44. Biochemical and Functional Characterization of the NurA-HerA Complex from Deinococcus radiodurans

    Article • Journal of Bacteriology, April 2015, ASM Journals

    Dr Ye Zhao

  45. A Mur Regulator Protein in the Extremophilic Bacterium Deinococcus radiodurans

    Article • PLOS One, September 2014, PLOS

    Dr Ye Zhao

  46. Structural and functional studies of MutS2 from Deinococcus radiodurans

    Article • DNA Repair, September 2014, Elsevier

    Dr Ye Zhao

  47. The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability

    Article • BDJ, April 2014, Springer Science + Business Media

    Dr Ye Zhao

  48. The key residue for SSB-RecO interaction is dispensable for Deinococcus radiodurans DNA repair in vivo

    Article • Acta Biochimica et Biophysica Sinica, March 2014, Oxford University Press (OUP)

    Dr Ye Zhao

  49. Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η

    Article • Proceedings of the National Academy of Sciences, April 2013, Proceedings of the National Academy of Sciences

    Dr Ye Zhao

  50. Extracellular dGMP Enhances Deinococcus radiodurans Tolerance to Oxidative Stress

    Article • PLOS One, January 2013, PLOS

    Dr Ye Zhao

  51. Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography

    Article • BIOPHYSICS, January 2013, Biophysical Society of Japan

    Teruya Nakamura, Dr Ye Zhao

  52. Watching DNA polymerase η make a phosphodiester bond

    Article • Nature, July 2012, Springer Science + Business Media

    Dr Ye Zhao, Teruya Nakamura

  53. Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin

    Article • Proceedings of the National Academy of Sciences, April 2012, Proceedings of the National Academy of Sciences

    Dr Ye Zhao

  54. Erratum: Structure and mechanism of human DNA polymerase η

    Article • Nature, August 2011, Springer Science + Business Media

    Dr Ye Zhao

  55. Both OB Folds of Single-Stranded DNA-Binding Protein Are Essential for Its ssDNA Binding Activity in Deinococcus radiodurans

    Article • Protein & Peptide Letters, October 2010, Bentham Science Publishers

    Dr Ye Zhao

  56. Structure and mechanism of human DNA polymerase η

    Article • Nature, June 2010, Springer Science + Business Media

    Dr Ye Zhao

  57. Involvement of RecG in H 2 O 2 -induced damage repair in Deinococcus radiodurans

    Article • Canadian Journal of Microbiology, July 2009, Canadian Science Publishing

    Dr Ye Zhao

  58. DrRRA: a novel response regulator essential for the extreme radioresistance of Deinococcus radiodurans

    Article • Molecular Microbiology, March 2008, Wiley

    Dr Ye Zhao

  59. A Novel OxyR Sensor and Regulator of Hydrogen Peroxide Stress with One Cysteine Residue in Deinococcus radiodurans

    Article • PLOS One, February 2008, PLOS

    Dr Ye Zhao