All Stories

  1. Associations between Serum Insulin-Like Growth Factor-Related Molecules and Colorectal Cancer Risk by Tumor Location: A Nested Case-Control Study
  2. Impact of Sensitive Circulating Tumor DNA Monitoring on CT Scan Intervals During Postoperative Colorectal Cancer Surveillance
  3. Targeted Dynamic Phospho-Proteogenomic Analysis of Gastric Cancer Cells Suggests Host Immunity Provides Survival Benefit
  4. Dynamic phospho-proteogenomic analysis of gastric cancer cells suggests host immunity provides survival benefit
  5. Association of serum superoxide dismutase activity and the incidence of colorectal cancer in a nested case-control study
  6. Esophageal intraepithelial squamous cell neoplasia with epidermalization—A case with molecular analysis
  7. Serum Soluble Fas Levels and Incidence of Liver Cancer in Nested Case–Control Study
  8. Impact of sensitive circulating tumor DNA monitoring on CT scan intervals during postoperative colorectal cancer surveillance
  9. Genomic analysis of an aggressive case with metastatic intrahepatic mucinous cholangiocarcinoma
  10. Individualized circulating tumor DNA monitoring in head and neck squamous cell carcinoma
  11. Mutation Analysis of Radioresistant Early-Stage Cervical Cancer
  12. DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes
  13. Early dynamics of circulating tumor DNA predict chemotherapy responses for patients with esophageal cancer
  14. Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo
  15. Early dynamics of circulating tumor DNA predict chemotherapy responses for patients with esophageal cancer
  16. Frequent Tumor Burden Monitoring of Esophageal Squamous Cell Carcinoma With Circulating Tumor DNA Using Individually Designed Digital Polymerase Chain Reaction
  17. Generation of functional liver tissue by establishing hepatobiliary connections ex vivo
  18. Mutation profiling of uterine cervical cancer patients treated with definitive radiotherapy
  19. Whole-exome sequencing of 79 xenografts as a potential approach for the identification of genetic variants associated with sensitivity to cytotoxic anticancer drugs
  20. Integrated genetic and epigenetic analysis of cancer‐related genes in non‐ampullary duodenal adenomas and intramucosal adenocarcinomas
  21. Aggressive variant of splenic marginal zone lymphoma characterized using a cancer panel test and treated with rituximab-containing chemotherapy
  22. Circulating-tumor DNA from Two Types of Blood Collection Tubes for Monitoring Tumor Burden Validated with Esophageal Squamous Cell Carcinoma Patients
  23. Combination of KRAS and SMAD4 mutations in formalin‐fixed paraffin‐embedded tissues as a biomarker for pancreatic cancer
  24. Frequent tumor burden monitoring of esophageal squamous cell carcinoma with circulating tumor DNA using individually designed digital PCR
  25. Genetic analyses of mosaic neurofibromatosis type 1 with giant café‐au‐lait macule, plexiform neurofibroma and multiple melanocytic nevi
  26. Chemotherapy after progression on nivolumab is essential for responders with genetic alterations of driver gene: Review of two recurrent/metastatic oral squamous cell carcinoma patients
  27. Significance of gene mutations in the Wnt signaling pathway in traditional serrated adenomas of the colon and rectum
  28. Renal angiomyolipoma (AML) harboring a missense mutation of TSC2 with copy-neutral loss of heterozygosity (CN-LOH)
  29. p53-induced ARVCF modulates the splicing landscape and supports the tumor suppressive function of p53
  30. Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis
  31. FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy
  32. Corrigendum to “Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer”
  33. Genomic characterization for familial cases with urothelial carcinoma
  34. Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer
  35. A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors
  36. Malignant paraganglioma of the posterior mediastinum: A case report with genetic analysis
  37. Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment
  38. DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling
  39. Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy
  40. Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma
  41. Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1
  42. Prognostic nutritional index and early mortality with percutaneous endoscopic gastrostomy
  43. Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors
  44. Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma
  45. Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis
  46. Targeted sequencing reveals genetic variants associated with sensitivity of 79 human cancer xenografts to anticancer drugs
  47. Identification and characterization of a metastatic suppressor BRMS1L as a target gene of p53
  48. Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing
  49. Fledglings in p53 signaling network
  50. Assessment of the quality of DNA from various formalin-fixed paraffin-embedded (FFPE) tissues and the use of this DNA for next-generation sequencing (NGS) with no artifactual mutation
  51. p53 mediates the suppression of cancer cell invasion by inducing LIMA1/EPLIN
  52. Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function
  53. TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells
  54. Systemic Prophylactic Antibiotics for the Modified Introducer Method for Percutaneous Endoscopic Gastrostomy
  55. Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target
  56. Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress
  57. The effect of forced expression of mutatedK-RASgene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy
  58. Genomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencing
  59. Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors
  60. Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing
  61. CRKL oncogene is downregulated by p53 through miR‐200s
  62. Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells
  63. MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions
  64. Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites
  65. Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness
  66. AKR1B10, a Transcriptional Target of p53, Is Downregulated in Colorectal Cancers Associated with Poor Prognosis
  67. The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma
  68. CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion
  69. Molecular Dissection of Premalignant Colorectal Lesions Reveals Early Onset of the CpG Island Methylator Phenotype
  70. A novel approach to cancer treatment using structural hybrids of the p53 gene family
  71. Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes
  72. CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation
  73. p53 Negatively Regulates the Hepatoma Growth Factor HDGF
  74. Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
  75. Epigenetic Alteration of DNA in Mucosal Wash Fluid Predicts Invasiveness of Colorectal Tumors
  76. Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene
  77. Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat
  78. DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae
  79. Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer
  80. N-Propionyl-Cysteaminylphenol-Magnetite Conjugate (NPrCAP/M) Is a Nanoparticle for the Targeted Growth Suppression of Melanoma Cells
  81. IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype
  82. Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity
  83. A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth
  84. Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma
  85. A Single Recombinant Adenovirus Expressing p53 and p21-targeting Artificial microRNAs Efficiently Induces Apoptosis in Human Cancer Cells
  86. CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-κB
  87. p53 Family Members Regulate the Expression of the Apolipoprotein D Gene
  88. LINE-1 Hypomethylation Is Associated with Increased CpG Island Methylation in Helicobacter pylori-Related Enlarged-Fold Gastritis
  89. Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer
  90. Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma
  91. In vitro transformation of adult rat hepatic progenitor cells into pancreatic endocrine hormone-producing cells
  92. Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models
  93. Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer
  94. Identification of Flotillin-2, a Major Protein on Lipid Rafts, as a Novel Target of p53 Family Members
  95. Gene Amplification and Overexpression of PRDM14 in Breast Cancers
  96. PRDM5 Identified as a Target of Epigenetic Silencing in Colorectal and Gastric Cancer
  97. Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors
  98. Antitumor effect of adenovirus-mediated p53 family gene transfer on osteosarcoma cell lines
  99. Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer
  100. Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer
  101. Activation of the ribosomal protein L13 gene in human gastrointestinal cancer
  102. Comparative Genome Analysis Identifies the Vitamin D Receptor Gene as a Direct Target of p53-Mediated Transcriptional Activation
  103. The role of T-fimbrin in the response to DNA damage: Silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents
  104. Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors
  105. The Ras Effector RASSF2 Is a Novel Tumor-Suppressor Gene in Human Colorectal Cancer
  106. Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes
  107. Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours
  108. Abnormal β-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features
  109. Aberrant Methylation and Silencing of theBNIP3Gene in Colorectal and Gastric Cancer
  110. Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-γ-induced HLA-DR expression in colorectal and gastric cancer cells
  111. Identification of SCN3B as a novel p53-inducible proapoptotic gene
  112. Aberrant Methylation and Histone Deacetylation Associated with Silencing of SLC5A8 in Gastric Cancer
  113. Ichikawa et al., ?Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in relation to differentiation of gastric cancer?.Int J Cancer 2004; 112:967-973
  114. Epigenetic inactivation of CHFR in human tumors
  115. Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Polı gene as a candidate for Par2
  116. Interleukin‐4‐expressing plasmid DNA inhibits reovirus type‐2‐triggered autoimmune insulitis in DBA/1 J suckling mice
  117. Induction of tenascin-C by tumor-specificEWS-ETS fusion genes
  118. The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors
  119. DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers
  120. Identification of theOsteopontin gene as a direct target of TP53
  121. Increased expression of T-fimbrin gene after DNA damage in CHO cells and inactivation of T-fimbrin by CpG methylation in human colorectal cancer cells
  122. Thep53Family Member Genes Are Involved in the Notch Signal Pathway
  123. Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer
  124. Jejunal carcinoid tumor mimicking leiomyosarcoma: preoperative diagnosis by endoscopic biopsy
  125. Mutational Analysis of the β-Catenin Gene in Gastric Carcinomas
  126. Identification of genes highly expressed in G2-arrested Chinese hamster ovary cells by differential display analysis
  127. Involvement of cyclooxygenase-2 in proliferation and morphogenesis induced by transforming growth factor α in gastric epithelial cells
  128. Subcapsular hematoma of the liver and pylethrombosis in the setting of cholestatic liver injury
  129. Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma