All Stories

  1. Disruptions in outer membrane-peptidoglycan interactions enhance bile salt resistance in O-antigen-producing E. coli

    Article • mBio, October 2025, ASM Journals

    Dr Yaoqin Hong

  2. Decoding gene essentiality in Streptococcus suis using Tn-seq and genome-scale metabolic modeling

    Article • Microbiology Spectrum, October 2025, ASM Journals

    Dr Yaoqin Hong

  3. Nitric oxide donor sodium nitroprusside serves as a source of iron supporting Pseudomonas aeruginosa growth and biofilm formation

    Article • Microbiology Spectrum, October 2025, ASM Journals

    Dr Yaoqin Hong

  4. Not too rigid nor too wobbly: Defining an optimal membrane fluidity range essential for biofilm formation in Escherichia coli

    Article • mLife, August 2025, Wiley

    Dr Yaoqin Hong

  5. Nitric oxide donor sodium nitroprusside serves as a source of iron supportingPseudomonas aeruginosagrowth and biofilm formation

    Article • March 2025, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  6. Disruptions in Outer Membrane-Peptidoglycan Interactions Enhance Bile Salt Resistance in O-antigen-ProducingE. coli

    Article • February 2025, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  7. Optimal membrane fluidity modulates biofilm formation inEscherichia coli

    Article • February 2025, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  8. Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate

    Article • Microbiology, January 2025, Society for General Microbiology

    Dr Yaoqin Hong, Dr Matthew Thomas Doyle

  9. Tolerance mechanisms in polysaccharide biosynthesis: Implications for undecaprenol phosphate recycling in Escherichia coli and Shigella flexneri

    Article • PLoS Genetics, January 2025, PLOS

    Dr Yaoqin Hong

  10. Bacterial suppressor-of-copper-sensitivity proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions

    Article • iScience, December 2024, Elsevier

    Dr Yaoqin Hong

  11. Unveiling the versatility of the thioredoxin framework: Insights from the structural examination of Francisella tularensis DsbA1

    Article • Computational and Structural Biotechnology Journal, December 2024, Elsevier

    Dr Yaoqin Hong

  12. Tolerance Mechanisms in Polysaccharide Biosynthesis: Implications for Undecaprenol Phosphate Recycling inEscherichia coliandShigella flexneri

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  13. Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  14. Determining glycosyltransferase functional order via lethality due to accumulated O-antigen intermediates, exemplified with Shigella flexneri O-antigen biosynthesis

    Article • Applied and Environmental Microbiology, June 2024, ASM Journals

    Dr Yaoqin Hong

  15. A conditional nature for the synthetical lethality between defects in lipid and peptidoglycan biosynthesis

    Article • Proceedings of the National Academy of Sciences, December 2023, Proceedings of the National Academy of Sciences

    Dr Yaoqin Hong

  16. Determining glycosyltransferase functional order via lethality due to accumulated O-antigen intermediates, exemplified withShigella flexneriO-antigen biosynthesis

    Article • December 2023, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  17. O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss

    Article • PLoS Genetics, October 2023, PLOS

    Dr Yaoqin Hong

  18. Extensive Diversity in Escherichia coli Group 3 Capsules Is Driven by Recombination and Plasmid Transfer from Multiple Species

    Article • Microbiology Spectrum, August 2023, ASM Journals

    Dr Yaoqin Hong

  19. O antigen biogenesis sensitisesEscherichia coliK-12 to bile salts, a likely cause for how it lost its O antigen

    Article • May 2023, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  20. Bacterial suppressor-of-copper-sensitivity (Scs) proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  21. Repeat-Unit Elongations To Produce Bacterial Complex Long Polysaccharide Chains, an O-Antigen Perspective

    Article • EcoSal Plus, January 2023, ASM Journals

    Dr Yaoqin Hong

  22. Cysteine-Dependent Conformational Heterogeneity of Shigella flexneri Autotransporter IcsA and Implications of Its Function

    Article • Microbiology Spectrum, December 2022, ASM Journals

    Dr Yaoqin Hong

  23. A method for increasing electroporation competence of Gram-negative clinical isolates by polymyxin B nonapeptide

    Article • Scientific Reports, July 2022, Springer Science + Business Media

    Dr Yaoqin Hong

  24. Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics

    Article • mSphere, June 2022, ASM Journals

    Dr Yaoqin Hong

  25. The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

    Article • Acta Crystallographica Section D Structural Biology, February 2022, International Union of Crystallography

    Dr Yaoqin Hong

  26. Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities

    Article • Antioxidants & Redox Signaling, July 2021, Mary Ann Liebert Inc

    Dr Yaoqin Hong, Dr. Santosh Panjikar

  27. Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance

    Article • FASEB BioAdvances, February 2021, Wiley

    Dr Yaoqin Hong

  28. A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

    Article • Scientific Reports, January 2021, Springer Science + Business Media

    Dr Yaoqin Hong

  29. High-throughput cell-based assays for the preclinical development of DsbA inhibitors as antivirulence therapeutics

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Dr Yaoqin Hong

  30. Two extremely divergent sequence forms of the genes that define Escherichia coli group 3 capsules suggest a very long history since their common ancestor

    Article • FEMS Microbiology Letters, April 2019, Oxford University Press (OUP)

    Dr Yaoqin Hong

  31. Development and retention of a primordial moonlighting pathway of protein modification in the absence of selection presents a puzzle

    Article • Proceedings of the National Academy of Sciences, January 2018, Proceedings of the National Academy of Sciences

    Dr Yaoqin Hong

  32. Phenolic composition, antioxidant and pancreatic lipase inhibitory activities of Chinese sumac (Rhus chinensis Mill.) fruits extracted by different solvents and interaction between myricetin-3-O -rhamnoside and quercetin-3-O -rhamnoside

    Article • International Journal of Food Science & Technology, November 2017, Wiley

    Dr Yaoqin Hong, Shengbao Cai

  33. Progress in Our Understanding of Wzx Flippase for Translocation of Bacterial Membrane Lipid-Linked Oligosaccharide

    Article • Journal of Bacteriology, July 2017, ASM Journals

    Dr Yaoqin Hong, Professor Peter Richard Reeves

  34. Model for the Controlled Synthesis of O-Antigen Repeat Units Involving the WaaL Ligase

    Article • mSphere, December 2015, ASM Journals

    Dr Yaoqin Hong, Professor Peter Richard Reeves, Yaoqin Hong

  35. Three Wzy polymerases are specific for particular forms of an internal linkage in otherwise identical O units

    Article • Microbiology, August 2015, Society for General Microbiology

    Dr Yaoqin Hong, Professor Peter Richard Reeves

  36. Inefficient translocation of a truncated O unit by a Salmonella Wzx affects both O-antigen production and cell growth

    Article • FEMS Microbiology Letters, April 2015, Oxford University Press (OUP)

    Dr Yaoqin Hong, Professor Peter Richard Reeves

  37. Diversity of O-Antigen Repeat Unit Structures Can Account for the Substantial Sequence Variation of Wzx Translocases

    Article • Journal of Bacteriology, February 2014, ASM Journals

    Dr Yaoqin Hong, Professor Peter Richard Reeves

  38. The WbaK acetyltransferase of Salmonella enterica group E gives insights into O antigen evolution

    Article • Microbiology, September 2013, Society for General Microbiology

    Professor Peter Richard Reeves, Dr Yaoqin Hong

  39. The Wzx translocases for Salmonella enterica O-antigen processing have unexpected serotype specificity

    Article • Molecular Microbiology, April 2012, Wiley

    Dr Yaoqin Hong, Professor Peter Richard Reeves, Yaoqin Hong