All Stories

  1. Aiming at Ideal Therapeutics-MOPr/DOPr or MOPr-DOPr Heteromertargeting Ligand

    Article • Current Topics in Medicinal Chemistry, December 2020, Bentham Science Publishers

    Dr Wakako Fujita

  2. Regulation of an Opioid Receptor Chaperone Protein, RTP4, by Morphine

    Article • Molecular Pharmacology, October 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Wakako Fujita, Professor Lakshmi Devi Devi

  3. G Protein–Coupled Receptor Heteromers

    Article • The Annual Review of Pharmacology and Toxicology, January 2016, Annual Reviews

    Dr Wakako Fujita, Dr Kevin Pfleger, Professor Lakshmi Devi Devi

  4. P-glycoprotein inhibitors improve effective dose and time of pregabalin to inhibit intermittent cold stress-induced central pain

    Article • Journal of Pharmacological Sciences, January 2016, Elsevier

    Dr Wakako Fujita

  5. Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers

    Article • Biochemical Pharmacology, December 2014, Elsevier

    Dr Wakako Fujita

  6. Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR Review 10

    Article • British Journal of Pharmacology, August 2014, Wiley

    Dr Wakako Fujita, Professor Lakshmi Devi Devi

  7. Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities

    Article • British Journal of Pharmacology, July 2014, Wiley

    Dr Wakako Fujita, Professor Lakshmi Devi Devi

  8. RhoA affects oral morphine analgesia depending on functional variation in intestinal P-glycoprotein induced by repeated etoposide treatment

    Article • European Journal of Pharmaceutical Sciences, December 2012, Elsevier

    Dr Wakako Fujita

  9. Involvement of matrix metalloproteinase-9 in the development of morphine tolerance

    Article • European Journal of Pharmacology, May 2012, Elsevier

    Dr Wakako Fujita

  10. Honokiol suppresses the development of post-ischemic glucose intolerance and neuronal damage in mice

    Article • Journal of Natural Medicines, January 2012, Springer Science + Business Media

    Dr Wakako Fujita

  11. Involvement of Ubiquitination in the Decrease of Intestinal P-Glycoprotein in a Streptozotocin-induced Diabetic Mouse Model

    Article • Drug Metabolism and Pharmacokinetics, January 2012, Japanese Society for the Study of Xenobiotics

    Dr Wakako Fujita

  12. Altered Intestinal P-glycoprotein Expression Levels Affect Pharmacodynamics under Diabetic Condition

    Article • YAKUGAKU ZASSHI, January 2012, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  13. Ischemic Stroke and Glucose Intolerance: a Review of the Evidence and Exploration of Novel Therapeutic Targets

    Article • Journal of Pharmacological Sciences, January 2012, Japanese Pharmacological Society

    Dr Wakako Fujita

  14. Ameliorating Effect of Hypothalamic Brain-Derived Neurotrophic Factor Against Impaired Glucose Metabolism After Cerebral Ischemic Stress in Mice

    Article • Journal of Pharmacological Sciences, January 2012, Japanese Pharmacological Society

    Dr Wakako Fujita

  15. The Involvement of Cleavage of Neural Cell Adhesion Molecule in Neuronal Death under Oxidative Stress Conditions in Cultured Cortical Neurons

    Article • Biological and Pharmaceutical Bulletin, January 2012, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  16. 糖尿病および一過性腸管虚血病態モデルにおける腸管P-glycoproteinの発現・機能変動と薬物動態変化

    Article • Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), January 2012, Japanese Society of Pharmaceutical Health Care and Sciences

    Dr Wakako Fujita

  17. Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein

    Article • Journal of Pharmacy and Pharmacology, December 2011, Wiley

    Dr Wakako Fujita

  18. Involvement of NCAM and FGF receptor signaling in the development of analgesic tolerance to morphine

    Article • European Journal of Pharmacology, December 2011, Elsevier

    Dr Wakako Fujita

  19. Altered intestinal P-glycoprotein expression levels in a monosodium glutamate-induced obese mouse model

    Article • Life Sciences, December 2011, Elsevier

    Dr Wakako Fujita

  20. ChemInform Abstract: Nitric Oxide Synthase Mediated Alteration of Intestinal P-Glycoprotein under Hyperglycemic Stress

    Article • ChemInform, September 2011, Wiley

    Dr Wakako Fujita

  21. ChemInform Abstract: Effectiveness of Metformin in Prevention of Development of Hyperglycemia and Neuronal Damage Caused by Ischemic Stress

    Article • ChemInform, September 2011, Wiley

    Dr Wakako Fujita

  22. Aβand Aδbut not C-fibres are involved in stroke related pain and allodynia: an experimental study in mice

    Article • Journal of Pharmacy and Pharmacology, February 2011, Wiley

    Dr Wakako Fujita

  23. Nitric Oxide Synthase-mediated Alteration of Intestinal P-glycoprotein under Hyperglycemic Stress

    Article • YAKUGAKU ZASSHI, January 2011, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  24. Effectiveness of Metformin in Prevention of Development of Hyperglycemia and Neuronal Damage Caused by Ischemic Stress

    Article • YAKUGAKU ZASSHI, January 2011, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  25. Regulatory Action of Nitric Oxide Synthase on Ileal P-glycoprotein Expression under Streptozotocin-Induced Diabetic Condition

    Article • Biological and Pharmaceutical Bulletin, January 2011, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  26. Effect of Orexin-A on Post-ischemic Glucose Intolerance and Neuronal Damage

    Article • Journal of Pharmacological Sciences, January 2011, Japanese Pharmacological Society

    Dr Wakako Fujita

  27. Decreased Expression of Intestinal P-glycoprotein Increases the Analgesic Effects of Oral Morphine in a Streptozotocin-induced Diabetic Mouse Model

    Article • Drug Metabolism and Pharmacokinetics, January 2011, Japanese Society for the Study of Xenobiotics

    Dr Wakako Fujita

  28. The Antinociceptive and Anti-inflammatory Action of the CHCl3-Soluble Phase and Its Main Active Component, Damnacanthal, Isolated from the Root of Morinda citrifolia

    Article • Biological and Pharmaceutical Bulletin, January 2011, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  29. 脳梗塞治療における新たなるアプローチ

    Article • Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), January 2011, Japanese Society of Pharmaceutical Health Care and Sciences

    Dr Wakako Fujita

  30. ChemInform Abstract: Involvement of Glycemic Control in the Inhibiting Effect of Morinda citrifolia on Cerebral Ischemia-Induced Neuronal Damage

    Article • ChemInform, September 2010, Wiley

    Dr Wakako Fujita

  31. The importance of regulation of blood glucose levels through activation of peripheral 5′-AMP-activated protein kinase on ischemic neuronal damage

    Article • Brain Research, September 2010, Elsevier

    Dr Wakako Fujita

  32. Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation

    Article • Journal of Pharmacy and Pharmacology, July 2010, Wiley

    Dr Wakako Fujita

  33. Morinda citrifolia fruit juice prevents ischemic neuronal damage through suppression of the development of post-ischemic glucose intolerance

    Article • Journal of Natural Medicines, June 2010, Springer Science + Business Media

    Dr Wakako Fujita

  34. Inducible nitric oxide synthase-mediated decrease of intestinal P-glycoprotein expression under streptozotocin-induced diabetic conditions

    Article • Life Sciences, March 2010, Elsevier

    Dr Wakako Fujita

  35. Inhibitory effect of anthraquinones isolated from the Noni (Morinda citrifolia) root on animal A-, B- and Y-families of DNA polymerases and human cancer cell proliferation

    Article • Food Chemistry, February 2010, Elsevier

    Dr Wakako Fujita

  36. Involvement of Glycemic Control in the Inhibiting Effect of Morinda citrifolia on Cerebral Ischemia-induced Neuronal Damage

    Article • YAKUGAKU ZASSHI, January 2010, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  37. Antinociceptive Effects of Docosahexaenoic Acid against Various Pain Stimuli in Mice

    Article • Biological and Pharmaceutical Bulletin, January 2010, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  38. Proposition and Evaluation of the Educational Activities for Effective Utilization of Opioids Performed by Pharmacists in Palliative Home Care

    Article • YAKUGAKU ZASSHI, January 2010, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  39. The development of glucose intolerance after focal cerebral ischemia participates in subsequent neuronal damage

    Article • Brain Research, July 2009, Elsevier

    Dr Wakako Fujita

  40. ChemInform Abstract: Protective Effect of Morinda citrifolia on the Ischemic Neuronal Damage

    Article • ChemInform, June 2009, Wiley

    Dr Wakako Fujita

  41. New anthraquinone glycosides from the roots of Morinda citrifolia

    Article • Fitoterapia, April 2009, Elsevier

    Dr Wakako Fujita

  42. The Attitude Survey of Medical Staff on the Participation of Community Pharmacists in the Palliative Home Care

    Article • YAKUGAKU ZASSHI, January 2009, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  43. Protective Effect of Morinda citrifolia on the Ischemic Neuronal Damage

    Article • YAKUGAKU ZASSHI, January 2009, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  44. Preventive Effect of Morinda citrifolia Fruit Juice on Neuronal Damage Induced by Focal Ischemia

    Article • Biological and Pharmaceutical Bulletin, January 2009, Pharmaceutical Society of Japan

    Dr Wakako Fujita, Junichiro Yamamoto

  45. Involvement of kappa opioid receptors in the inhibition of receptor desensitization and PKC activation induced by repeated morphine treatment

    Article • Journal of Pharmacy and Pharmacology, September 2008, Wiley

    Dr Wakako Fujita

  46. A Role and Necessity of a School Pharmacist at the Time of a Disaster

    Article • YAKUGAKU ZASSHI, January 2008, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  47. Chemical Constituents of Morinda citrifolia Roots Exhibit Hypoglycemic Effects in Streptozotocin-Induced Diabetic Mice

    Article • Biological and Pharmaceutical Bulletin, January 2008, Pharmaceutical Society of Japan

    Dr Wakako Fujita

  48. Ｃ型慢性肝炎に対するペグインターフェロン／リバビリン併用療法の効果と脂質要因との関係

    Article • Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), January 2008, Japanese Society of Pharmaceutical Health Care and Sciences

    Dr Wakako Fujita

  49. Involvement of kappa opioid receptors in formalin-induced inhibition of analgesic tolerance to morphine in mice

    Article • Journal of Pharmacy and Pharmacology, August 2007, Wiley

    Dr Wakako Fujita

  50. Negative Relationship Between Morphine Analgesia and P-Glycoprotein Expression Levels in the Brain

    Article • Journal of Pharmacological Sciences, January 2007, Japanese Pharmacological Society

    Dr Wakako Fujita

  51. Involvement of serine/threonine protein phosphatases sensitive to okadaic acid in restraint stress-induced hyperlocomotion in cocaine-sensitized mice

    Article • British Journal of Pharmacology, June 2006, Wiley

    Dr Wakako Fujita

  52. Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP2A and PP5 estimated by tail-pinch test in mice

    Article • Brain Research, September 2005, Elsevier

    Dr Wakako Fujita

  53. Activation of Spinal Anti-analgesic System Following Electroacupuncture Stimulation in Rats

    Article • Journal of Pharmacological Sciences, January 2005, Japanese Pharmacological Society

    Dr Wakako Fujita

  54. Neuronal death mode switch and neurogenesis as in vivo neuroprotection.

    Article • Folia Pharmacologica Japonica, January 2002, Japanese Pharmacological Society

    Dr Wakako Fujita

  55. Serum-free induced neuronal apoptosis-like cell death is independent of caspase activity

    Article • Molecular Brain Research, May 2000, Elsevier

    Dr Wakako Fujita