Dr Vitaly V Ganusov
University of Tennessee Knoxville
Professor, Life Sciences
United States
My co-authors include
Professor Rob J de Boer
My Publications
Mathematical modeling suggests that a single Plasmodium-specific CD8 T cell can elimina...
May 2022
Evaluating impact of experimental design on accuracy of parameter estimation and model ...
April 2022
Mathematical Modeling Suggests Cooperation of Plant-Infecting Viruses
Viruses
March 2022
Liver Environment–Imposed Constraints Diversify Movement Strategies of Liver-Localized ...
The Journal of Immunology
February 2022
Mathematical modeling suggests cooperation of plant-infecting viruses
December 2021
Enhancing Quantitative and Data Science Education for Graduate Students in Biomedical S...
December 2021
Platelets are dispensable for the ability of CD8+ T cells to accumulate, patrol, kill a...
November 2021
Negative correlation between average speed and average turning angle naturally arises f...
January 2021
A minority of liver-localized CD8 T cells demonstrate difficult-to-detect attraction to...
December 2020
Impact of oseltamivir treatment on influenza A and B dynamics in human volunteers
November 2020
Environment-imposed constraints make Brownian walkers efficient searchers
November 2020
Experimental determination of the force of malaria infection reveals a non-linear relat...
PLoS Pathogens
May 2020
Experimental Determination of the Force of Malaria Infection Reveals a Non-Linear Relat...
November 2019
Erratum for Hoft et al., “The Rate of CD4 T Cell Entry into the Lungs during Mycobacter...
Infection and Immunity
August 2019
Defining Kinetic Properties of HIV-Specific CD8+ T-Cell Responses in Acute Infection
Microorganisms
March 2019
Mathematical modeling suggests that benefits of short or long antibiotic treatment depe...
February 2019
Defining Kinetic Properties of HIV-Specific CD8<sup>+</sup> T-cell Responses in Acute I...
January 2019
Estimating residence times of lymphocytes in ovine lymph nodes: Supplemental Information
January 2019
Clustering of activated CD8 T cells around malaria-infected hepatocytes is rapid and is...
December 2018
Cutting Edge: IL-1R1 Mediates Host Resistance toMycobacterium tuberculosisbyTrans-Prote...
The Journal of Immunology
August 2018
Time Intervals in Sequence Sampling, Not Data Modifications, Have a Major Impact on Est...
Viruses
February 2018
Using mathematical modeling to define kinetic properties of HIV-specific CD8...
July 2017
Strong Inference in Mathematical Modeling: A Method for Robust Science in the Twenty-Fi...
Frontiers in Microbiology
July 2016
Quantifying Limits on Replication, Death, and Quiescence of Mycobacterium tuberculosis ...
Frontiers in Microbiology
June 2016
CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tub...
PLoS Pathogens
May 2016
Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes
PLoS Computational Biology
October 2015
Evaluating contribution of the cellular and humoral immune responses to the control of ...
Veterinary Research
June 2015
Simple Mathematical Models Do Not Accurately Predict Early SIV Dynamics
Viruses
March 2015
Mathematical modeling provides kinetic details of the human immune response to vaccination
Frontiers in Cellular and Infection Microbiology
January 2015
Plasmodium Suppresses Expansion of T Cell Responses to Heterologous Infections
The Journal of Immunology
December 2014
Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism
PLoS Computational Biology
May 2014
Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immu...
PLoS Computational Biology
January 2014
Classification of T cell movement tracks allows for prediction of cell function
International Journal of Computational Biology and Drug Design
January 2014
In vivo imaging of CD8 <sup>+</sup> T cell-mediated elimination...
Proceedings of the National Academy of Sciences
May 2013
A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of...
Journal of The Royal Society Interface
March 2013
Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses
Journal of Statistical Mechanics Theory and Experiment
January 2013
Cellular and population plasticity of helper CD4+ T cell responses
Frontiers in Physiology
January 2013
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape
Journal of Clinical Investigation
December 2012
A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of...
Journal of The Royal Society Interface
October 2012
Evolution of viral life-cycle in response to cytotoxic T lymphocyte-mediated immunity
Journal of Theoretical Biology
October 2012
Mtb-Specific CD27low CD4 T Cells as Markers of Lung Tissue Destruction during Pulmonary...
PLoS ONE
August 2012
Early Low-Titer Neutralizing Antibodies Impede HIV-1 Replication and Select for Virus E...
PLoS Pathogens
May 2012
Distinct Kinetics of Gag-Specific CD4+ and CD8+ T Cell Responses during Acute HIV-1 Inf...
The Journal of Immunology
January 2012
Fitness Costs and Diversity of the Cytotoxic T Lymphocyte (CTL) Response Determine the ...
Journal of Virology
August 2011
Killing of Targets by CD8+ T Cells in the Mouse Spleen Follows the Law of Mass Action
PLoS ONE
January 2011
Stochastic Models of Lymphocyte Proliferation and Death
PLoS ONE
September 2010
Persistence of viral infection despite similar killing efficacy of antiviral CD8+ T cel...
Virology
September 2010
Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ul...
PLoS ONE
August 2010
In Mice, Tuberculosis Progression Is Associated with Intensive Inflammatory Response an...
PLoS ONE
May 2010
Explicit Kinetic Heterogeneity: Mathematical Models for Interpretation of Deuterium Lab...
PLoS Computational Biology
February 2010
The first T cell response to transmitted/founder virus contributes to the control of ac...
The Journal of Experimental Medicine
June 2009
Lymphocyte kinetics in health and disease
Trends in Immunology
April 2009
Estimating In Vivo Death Rates of Targets due to CD8 T-Cell-Mediated Killing
Journal of Virology
September 2008
Do most lymphocytes in humans really reside in the gut?
Trends in Immunology
December 2007
Discriminating between Different Pathways of Memory CD8+ T Cell Differentiation
The Journal of Immunology
October 2007
Dynamics of CD8+ T Cell Responses during Acute and Chronic Lymphocytic Choriomeningitis...
The Journal of Immunology
August 2007
IL-2 Regulates Expansion of CD4+ T Cell Populations by Affecting Cell Death: Insights f...
The Journal of Immunology
July 2007
Estimating Lymphocyte Division and Death Rates from CFSE Data
The Bulletin of Mathematical Biophysics
May 2006
IMPERFECT VACCINES AND THE EVOLUTION OF PATHOGENS CAUSING ACUTE INFECTIONS IN VERTEBRATES
Evolution
May 2006
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection
PLoS Computational Biology
January 2006
How Does Cross-Reactive Stimulation Affect the Longevity of CD8+ T Cell Memory?
PLoS Computational Biology
January 2006
Pathology during acute infections: contributions of intracellular pathogens and the CTL...
Proceedings of the Royal Society B Biological Sciences
May 2005
Quantifying cell turnover using CFSE data
Journal of Immunological Methods
March 2005
The role of models in understanding CD8+ T-cell memory
Nature Reviews Immunology
January 2005
The rescaling method for quantifying the turnover of cell populations
Journal of Theoretical Biology
November 2003
Trade-offs and the evolution of virulence of microparasites: do details matter?
Theoretical Population Biology
September 2003
The role of the cytotoxic T-lymphocyte response and virus cytopathogenicity in the viru...
Proceedings of the Royal Society B Biological Sciences
July 2003
Evolution of virulence: adaptive or not?
Trends in Microbiology
March 2003
Estimating the Instability Parameters of Plasmid-Bearing Cells. I. Chemostat Culture
Journal of Theoretical Biology
November 2002
WITHIN-HOST POPULATION DYNAMICS AND THE EVOLUTION OF MICROPARASITES IN A HETEROGENEOUS ...
Evolution
February 2002
Computer modeling of the biotic cycle formation in a closed ecological system
Advances in Space Research
January 2001
Modelling of genetically engineered microorganisms introduction in closed artificial mi...
Advances in Space Research
January 1999