All Stories

  1. Intestinal Ketogenesis and Permeability

    Article • International Journal of Molecular Sciences, June 2024, MDPI AG

    Ville Wallenius

  2. Morphological Adaptation in the Jejunal Mucosa after Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy Volunteers: Data from a Randomized Crossover Study

    Article • Nutrients, October 2022, MDPI AG

    Ville Wallenius

  3. A Fatty Diet Induces a Jejunal Ketogenesis Which Inhibits Local SGLT1-Based Glucose Transport via an Acetylation Mechanism—Results from a Randomized Cross-Over Study between Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy Volunteers

    Article • Nutrients, May 2022, MDPI AG

    Ville Wallenius

  4. The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development

    Article • Science Advances, April 2022, American Association for the Advancement of Science

    Ville Wallenius

  5. Healthy Subcutaneous and Omental Adipose Tissue Is Associated with High Expression of Extracellular Matrix Components

    Article • International Journal of Molecular Sciences, January 2022, MDPI AG

    Ville Wallenius

  6. Glycemic Control and Metabolic Adaptation in Response to High-Fat versus High-Carbohydrate Diets—Data from a Randomized Cross-Over Study in Healthy Subjects

    Article • Nutrients, September 2021, MDPI AG

    Ville Wallenius

  7. The BAriatic surgery SUbstitution and nutrition (BASUN) population: a data-driven exploration of predictors for obesity

    Article • BMC Endocrine Disorders, September 2021, Springer Science + Business Media

    Ville Wallenius

  8. Intestinal sodium/glucose cotransporter 3 expression is epithelial and downregulated in obesity

    Article • Life Sciences, February 2021, Elsevier

    Ville Wallenius

  9. Glycocholic acid and butyrate synergistically increase vitamin D-induced calcium uptake in Caco-2 intestinal epithelial cell monolayers

    Article • Bone Reports, December 2020, Elsevier

    Ville Wallenius

  10. Potential Benefits and Harms of Gastric Bypass Surgery in Obese Individuals With Type 1 Diabetes: A Nationwide, Matched, Observational Cohort Study

    Article • Diabetes Care, October 2020, American Diabetes Association

    Ville Wallenius

  11. Sleeve gastrectomy and Roux-en-Y gastric bypass in the treatment of type 2 diabetes. Two-year results from a Swedish multicenter randomized controlled trial

    Article • Surgery for Obesity and Related Diseases, August 2020, Elsevier

    Ville Wallenius

  12. Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of follow-up

    Article • Surgical Endoscopy, April 2020, Springer Science + Business Media

    Ville Wallenius

  13. Fucose-Galactose Polymers Inhibit Cholera Toxin Binding to Fucosylated Structures and Galactose-Dependent Intoxication of Human Enteroids

    Article • ACS Infectious Diseases, March 2020, American Chemical Society (ACS)

    Ville Wallenius

  14. Design and baseline data in the BAriatic surgery SUbstitution and Nutrition study (BASUN): a 10-year prospective cohort study

    Article • BMC Endocrine Disorders, February 2020, Springer Science + Business Media

    Ville Wallenius

  15. The gut microbiota is a major regulator of androgen metabolism in intestinal contents

    Article • AJP Endocrinology and Metabolism, December 2019, American Physiological Society

    Ville Wallenius

  16. Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis: a mechanism targeted by Roux-en-Y gastric bypass surgery but not by preoperative very-low-calorie diet

    Article • Gut, November 2019, BMJ

    Ville Wallenius

  17. Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Ville Wallenius

  18. Rates and types of injuries during the three consecutive years 2016 to 2018 of the Vätternrundan—One of the world’s largest and longest bicycle races

    Article • Traffic Injury Prevention, August 2019, Taylor & Francis

    Ville Wallenius

  19. Proteomic Approach to the Potential Role of Angiotensin II in Barrett Dysplasia

    Article • PROTEOMICS - CLINICAL APPLICATIONS, January 2019, Wiley

    Ville Wallenius

  20. Biliopancreatic Diversion is associated with greater increases in energy expenditure than Roux-en-Y Gastric Bypass

    Article • PLOS One, April 2018, PLOS

    Ville Wallenius

  21. GM1 ganglioside-independent intoxication by Cholera toxin

    Article • PLoS Pathogens, February 2018, PLOS

    Ville Wallenius

  22. Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells

    Article • ACS Infectious Diseases, February 2018, American Chemical Society (ACS)

    Ville Wallenius

  23. Glycemic Control after Sleeve Gastrectomy and Roux-En-Y Gastric Bypass in Obese Subjects with Type 2 Diabetes Mellitus

    Article • Obesity Surgery, December 2017, Springer Science + Business Media

    Ville Wallenius

  24. Obesity-induced changes in lipid mediators persist after weight loss

    Article • International Journal of Obesity, November 2017, Springer Science + Business Media

    Ville Wallenius

  25. AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin

    Article • Diabetologia, February 2017, Springer Science + Business Media

    Ville Wallenius

  26. Efficacy and safety of bariatric surgery for craniopharyngioma-related hypothalamic obesity: a matched case–control study with 2 years of follow-up

    Article • International Journal of Obesity, October 2016, Nature

    Mr Mark Wijnen, JAMJL Janssen, Professor Gudmundur Johannsson, Ville Wallenius

  27. Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa

    Article • Journal of the Renin-Angiotensin-Aldosterone System, August 2015, SAGE Publications

    Ville Wallenius

  28. Roux-en-Y Gastric Bypass Surgery Increases Respiratory Quotient and Energy Expenditure during Food Intake

    Article • PLOS One, June 2015, PLOS

    Ville Wallenius

  29. Angiotensin II exerts dual actions on sodium-glucose transporter 1-mediated transport in the human jejunal mucosa

    Article • Scandinavian Journal of Gastroenterology, April 2015, Taylor & Francis

    Ville Wallenius

  30. Surgery in the treatment of type 2 diabetes mellitus

    Article • Scandinavian Journal of Surgery, January 2015, SAGE Publications

    Ville Wallenius

  31. Expression of tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery

    Article • Surgery for Obesity and Related Diseases, January 2015, Elsevier

    Ville Wallenius

  32. Bone mineral density and expression of vitamin D receptor-dependent calcium uptake mechanisms in the proximal small intestine after bariatric surgery

    Article • BJS, September 2014, Oxford University Press (OUP)

    Ville Wallenius

  33. Correction: Gastric Bypass Surgery Is Followed by Lowered Blood Pressure and Increased Diuresis - Long Term Results from the Swedish Obese Subjects (SOS) Study

    Article • PLOS One, May 2013, PLOS

    Ville Wallenius

  34. Gastric Bypass Surgery Is Followed by Lowered Blood Pressure and Increased Diuresis - Long Term Results from the Swedish Obese Subjects (SOS) Study

    Article • PLOS One, November 2012, PLOS

    Ville Wallenius

  35. Interleukin-6 mediates exercise-induced increase in insulin sensitivity in mice

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, May 2012, Wiley

    Ville Wallenius

  36. Central Nervous System Lipocalin-Type Prostaglandin D2-Synthase is Correlated with Orexigenic Neuropeptides, Visceral Adiposity and Markers of the Hypothalamic-Pituitary-Adrenal Axis in Obese Humans

    Article • Journal of Neuroendocrinology, May 2011, Wiley

    Ville Wallenius

  37. The Lipocalins Retinol-Binding Protein-4, Lipocalin-2 and Lipocalin-Type Prostaglandin D2-Synthase Correlate with Markers of Inflammatory Activity, Alcohol Intake and Blood Lipids, But not with Insulin Sensitivity in Metabolically Healthy 58-year-Old S...

    Article • Experimental and Clinical Endocrinology & Diabetes, November 2010, Thieme Publishing Group

    Ville Wallenius

  38. Erythrocyte sodium-lithium countertransport activity is inversely correlated to adiponectin, retinol binding protein 4 and body height

    Article • Scandinavian Journal of Clinical and Laboratory Investigation, September 2010, Taylor & Francis

    Ville Wallenius

  39. Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

    Article • Journal of Applied Physiology, February 2007, American Physiological Society

    Ville Wallenius

  40. Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice

    Article • AJP Regulatory Integrative and Comparative Physiology, September 2006, American Physiological Society

    Ville Wallenius

  41. Interleukin-1 System Gene Polymorphisms Are Associated with Fat Mass in Young Men

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2006, Endocrine Society

    Ville Wallenius

  42. Increased Levels of Acylation-Stimulating Protein in Interleukin-6-Deficient (IL-6−/−) Mice

    Article • Endocrinology, June 2006, Endocrine Society

    Ville Wallenius

  43. Mature-Onset Obesity in Interleukin-1 Receptor I Knockout Mice

    Article • Diabetes, April 2006, American Diabetes Association

    Ville Wallenius

  44. Up-regulation of the high-affinity pyrimidine-preferring nucleoside transporter concentrative nucleoside transporter 1 by tumor necrosis factor-alpha and interleukin-6 in liver parenchymal cells

    Article • Journal of Hepatology, October 2004, Elsevier

    Ville Wallenius

  45. Lack of Complement Factor C3, but Not Factor B, Increases Hyperlipidemia and Atherosclerosis in Apolipoprotein E−/− Low-Density Lipoprotein Receptor−/− Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2004, Wolters Kluwer Health

    Ville Wallenius

  46. The therapeutic potential of interleukin-6 in treating obesity

    Article • Expert Opinion on Biological Therapy, October 2003, Informa Healthcare

    Ville Wallenius

  47. Interleukin-6 Levels in the Central Nervous System Are Negatively Correlated with Fat Mass in Overweight/Obese Subjects

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2003, Endocrine Society

    Ville Wallenius

  48. On the site and mechanism of action of the anti-obesity effects of interleukin-6

    Article • Growth Hormone & IGF Research, August 2003, Elsevier

    Ville Wallenius

  49. Intracerebroventricular interleukin-6 treatment decreases body fat in rats

    Article • Biochemical and Biophysical Research Communications, April 2002, Elsevier

    Ville Wallenius

  50. Interleukin-6-deficient mice develop mature-onset obesity

    Article • Nature Medicine, January 2002, Springer Science + Business Media

    Ville Wallenius

  51. Liver-Derived IGF-I Regulates GH Secretion at the Pituitary Level in Mice

    Article • Endocrinology, November 2001, Endocrine Society

    Ville Wallenius

  52. Retarded Liver Growth in Interleukin-6-Deficient and Tumor Necrosis Factor Receptor-1-Deficient Mice1

    Article • Endocrinology, July 2001, Endocrine Society

    Ville Wallenius

  53. Retarded Liver Growth in Interleukin-6-Deficient and Tumor Necrosis Factor Receptor-1-Deficient Mice

    Article • Endocrinology, July 2001, Endocrine Society

    Ville Wallenius

  54. Normal pharmacologically-induced, but decreased regenerative liver growth in interleukin-6-deficient (IL-6−/−) mice

    Article • Journal of Hepatology, December 2000, Elsevier

    Ville Wallenius

  55. Overexpression of the Hepatocyte Growth Factor (HGF) Receptor (Met) and Presence of a Truncated and Activated Intracellular HGF Receptor Fragment in Locally Aggressive/Malignant Human Musculoskeletal Tumors

    Article • American Journal Of Pathology, March 2000, Elsevier

    Ville Wallenius

  56. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

    Article • Proceedings of the National Academy of Sciences, June 1999, Proceedings of the National Academy of Sciences

    Ville Wallenius

  57. Amplification and overexpression of the hepatocyte growth factor receptor (HGFR/MET) in rat DMBA sarcomas

    Article • Oncogene, May 1999, Springer Science + Business Media

    Ville Wallenius

  58. Hepatocyte-stimulated expression of hepatocyte growth factor (HGF) in cultured rat hepatic stellate cells

    Article • Journal of Hepatology, January 1999, Elsevier

    Ville Wallenius

  59. Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1in Cultured Hepatic Stellate Cells1

    Article • Endocrinology, November 1997, Endocrine Society

    Ville Wallenius

  60. Changes in expression of CCAAT/enhancer binding protein α (C/EBPα) and C/EBPβ in rat liver after partial hepatectomy but not after treatment with cyproterone acetate

    Article • Journal of Hepatology, November 1997, Elsevier

    Ville Wallenius

  61. Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor  1 in Cultured Hepatic Stellate Cells

    Article • Endocrinology, November 1997, Endocrine Society

    Ville Wallenius

  62. Chromosomal localization of rat hepatocyte growth factor (Hgf) and HGF receptor (Met) and characterization of HGF receptor cDNA

    Article • Mammalian Genome, September 1997, Springer Science + Business Media

    Ville Wallenius