All Stories

  1. Anticancer potential of 1,2,3-triazole-tethered isonicotinate hybrids: Synthesis, in-silico studies, in-vitro studies and MD simulation
  2. Emerging Anti-Cancer and Repurposed Therapies for Overcoming Multidrug Resistance in Lung Cancer
  3. Molecular modelling and structure-activity relationship of pyrrolo[2,3- d ]pyrimidine derivatives as potent DNA gyrase B inhibitors
  4. Synthesis, characterization, biological screening and in silico studies of novel pyrazole-chalcone derivatives as potent aromatase inhibitors for breast cancer therapy
  5. Enhanced Tumor Treatment Outcomes of PEGylated Liposomal Gefitinib in Non-Small Cell Lung Cancer: A Comprehensive Preclinical Evaluation with Superior Therapeutic Efficacy
  6. Integrated synthesis, characterization, and computational analysis of 1H pyrrole-1,2,4-oxadiazole hybrids as anticancer agents
  7. Molecular Docking, Dynamics, and Cytotoxicity Assessment of Pyrazolo[1,5‐ a ]pyrimidine Derivatives Against Breast Cancer
  8. Integrated computational and preclinical evaluation of novel synthetic pyrazole pyrazoline thiazole derivative for breast cancer therapeutics
  9. Harnessing the Power of Ferulic Acid: A Comprehensive Review of its Therapeutic Mechanisms, Delivery Innovations, and Clinical Impact
  10. Pharmaceutical Industry Manufacturing Trend for Tablet Dosage Forms and Opportunities for the Future; A Case Study of Current Practice and Future Developments
  11. Design, Synthesis, and Evaluation of Nitroimidazole N-arylacetamides as Anti-TB Agents
  12. Unveiling the Potential of Morpholinium Surface Active Ionic Liquids for Epidermal Growth Factor Receptor Inhibition: Synthesis, Integrating Molecular Docking, Dynamics, and In Vitro Studies
  13. Green Synthesis of Pyrazole Linked Thiazole Derivatives With Enhanced Anti‐Breast Cancer Activity: Water Extract of Banana Peel‐Mediated Protocol, Anticancer Screening, Epidermal Growth Factor Receptor Inhibition, In Silico Absorption–Distribution–Meta...
  14. PEG‐400 Mediated Synthesis of Benzo[d]Imidazo[2,1‐b]Thiazoles as Bioactive Scaffolds: Antibreast Cancer Potential, EGFR Inhibition, Antioxidant Study, Molecular Docking, and DFT Insights
  15. Integrating network pharmacology and in vivo study to explore the anti-Alzheimer’s potential of Bergenia ligulata and Nelumbo nucifera
  16. Role of human microbiota in facilitating the metastatic journey of cancer cells
  17. Asciminib - ABL Kinase Inhibitor in the Treatment of Philadelphia Chromosome Positive Chronic Myeloid Leukemia: Chemistry and Pharmacology Perspectives
  18. Design, synthesis, computational studies and evaluation of novel 2, 4, 5-trisubstituted pyrimidine derivatives for anticancer activity against MCF-7 and A549 cell lines
  19. Unlocking the potential of novel hybrid lipid polymer nanoparticles in redefining camptothecin delivery: Achieving controlled release, enhanced cytotoxicity, and improved pharmacokinetics for colorectal cancer therapy
  20. Machine Learning-Based Prediction of Drug Solubility in Lipidic Environments: The Sol_ME Tool for Optimizing Lipid-Based Formulations with a Preliminary Apalutamide Case Study
  21. A New Green and Efficient Method for Pyranopyrazoles Synthesis in a Single Pot Using Multiple Components, In Silico Pharmacokinetics with Cytotoxic Assessments
  22. Hydrazide-Hydrazone Derivatives and Their Antitubercular Activity
  23. Investigating the role of natural flavonoids in VEGFR inhibition: Molecular modelling and biological activity in A549 lung cancer cells
  24. One-Pot multicomponent synthesis of novel pyrazole-linked thiazolyl-pyrazolines: Molecular docking and cytotoxicity assessment on breast and lung cancer cell-lines
  25. Eco-friendly Approaches to Chromene Derivatives: A Comprehensive Review of Green Synthesis Strategies
  26. Development and Characterization of Novel Solid Self Nanoemulsifying Drug Delivery System of Fimasartan
  27. Novel approaches to improve systemic bioavailability of curcumin using probiotics for rotenone-induced Parkinson’s disease in rodents
  28. Pharmacology of caffeine
  29. Theaflavins in tea
  30. Novel quinolinyl-thiazole hybrid candidates bearing N -methyl piperazine as potential anti-breast cancer agents: synthesis, biological evaluation and computational studies
  31. Design, Synthesis, Computational Studies and Evaluation of Novel Hybrid Bipyrimidine Analogues for Anticancer Activity against MCF-7 and A549 Cell Lines
  32. Quality by Design Approach Driven Development and Validation of Reverse Phase‐High‐Performance Liquid Chromatography Methodology for Dual Quantification of Aspirin and Rivaroxaban
  33. Structural Insights of PD-1/PD-L1 Axis: An In silico Approach
  34. Synthesis and InhA Inhibition of Imidazo[1,2-a]pyridine Derivatives as Anti-Tuberculosis Agents
  35. Investigating the Antioxidant Capacity of Newly Synthesized Flavonoids via DPPH Assay
  36. Pharmaceutical Market Access in Latin America: Analyzing Approval Requirements in Three Key Nations: Ecuador, Dominican Republic and Nicaragua
  37. Hydrazide–Hydrazones as Potential Antitubercular Agents: An Overview of the Literature (1999–2023)
  38. Development and application of RP–HPLC method for estimation and evaluation of stability of brinzolamide in ophthalmic formulation
  39. Computational Exploration of Naturally Occurring Flavonoids as TGF‐β Inhibitors in Breast Cancer: Insights from Docking and Molecular Dynamics Simulations and In‐vitro Cytotoxicity Study
  40. Decrypting the multifaceted peripheral neuropathy based on molecular pathology and therapeutics: a comprehensive review
  41. Synthesis, in silico studies and in vitro cytotoxicity evaluation of novel posaconazole derivative as a ALK TK inhibitor
  42. Molecular Docking, In silico ADMET Study and Synthesis of Quinoline Derivatives as Dihydrofolate Reductase (DHFR) Inhibitors: A Solvent-free One-pot Green Approach Through Sonochemistry
  43. Development of stable formulations of pemetrexed
  44. NOVEL IMIDAZOLE CONTAINING CHALCONE DERIVATIVES AS AN AROMATASE INHIBITOR: SYNTHESIS, DOCKING STUDIES, BIOLOGICAL SCREENING AND ADME STUDIES
  45. Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment
  46. Emerging green synthetic routes for thiazole and its derivatives: Current perspectives
  47. A Review of the Therapeutic Importance of Indole Scaffold in Drug Discovery
  48. Prominent Targets for Cancer Care: Immunotherapy Perspective
  49. Nanomaterials as drug delivery agents for overcoming the blood-brain barrier: A comprehensive review
  50. Simultaneous Estimation of Fimasartan potassium trihydrate and Atorvastatin calcium with Greenness Assessment using HPLC and UV Spectrophotometric Methods
  51. Optimization of poly(Ε-caprolactone) based biodegradable in situ porous drug-eluting insert of BCS class II/IV drug for targeted application
  52. Molecular pathology and therapeutics of the diabetic foot ulcer; comprehensive reviews
  53. Review on Determination of Berberine in Biological and Pharmaceutical Matrices: An Analytical and Therapeutic Perspective
  54. ASSESSMENT OF KNOWLEDGE, ATTITUDE AND BEHAVIOR ON ADVERSE DRUG REACTIONS BETWEEN COMMUNITY AND HOSPITAL PHARMACISTS: A QUESTIONNAIRE-BASED STUDY
  55. A Simple, Precise, and Sensitive RP-HPLC Method for Quantification of Teneligliptin Hydrobromide and Metformin Hydrochloride: Development and Validation
  56. Virtual Screening, Molecular Docking Studies and DFT Calculations of Novel Anticancer Flavonoids as Potential VEGFR-2 Inhibitors
  57. Sol_Me: Unleashing the Power of Machine Learning for Enhanced Lipid-Based Formulation Design and Predicting Drug Solubility in Oil and Surfactant
  58. Xenobots: Applications in Drug Discovery
  59. Review on Analytical Methodologies, Chemical and Therapeutic Perspectives of Curcumin: A Ubiquitous Natural Molecule
  60. Co-administration of Coenzyme Q10 and HMG-CoA Reductase Inhibitor Attenuates Oxidative Stress, TGF-β, TNF-α, Nitrite Content and MPO Levels against Experimentally-induced Diabetic Nephropathy in Rats
  61. Anti-ulcer Activities of Herbal Remedies as Alternative Therapy
  62. Catechins and Theaflavins: An Overview on Therapeutic Application
  63. Novel Therapeutic Intervention using Coenzyme Q10 and Insulin Sensitizer on Experimentally- Initiated Diabetic Neuropathy
  64. Role of Natural and Synthetic Flavonoids as Potential Aromatase Inhibitors in Breast Cancer: Structure-Activity Relationship Perspective
  65. Chemopreventive Role of Phytoconstituents in Breast Cancer: An Integration Therapy
  66. DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF LORNOXICAM AND TOLPERISONE HYDROCHLORIDE IN BULK DRUG AND COMBINED DOSAGE FORM
  67. Probiotic Formulations: A Patent Landscaping Using the Text Mining Approach
  68. A review on synthetic investigation for quinoline- recent green approaches
  69. In Vitro Cytotoxicity and Aromatase Inhibitory Activity of Flavonoids: Synthesis, Molecular Docking and In silico ADME Prediction
  70. Comprehensive Review of Ethnopharmacological and Phytochemical Aspects of Nutraceuticals in Psychiatric Disorders
  71. Comprehensive review on repurposing of approved medicine in the management of COVID-19 infection
  72. Practicality Assessment of a Frugal Nanoparticle Generator: Opening Doors to Nano Pharmaceuticals for the Researchers and Students of Underprivileged Academic Institutions
  73. Molecular modeling and ADMET predictions of flavonoids as prospective aromatase inhibitors
  74. Development of Natural Bioactive Alkaloids: Anticancer Perspective
  75. Piperine: Medicinal, Analytical and Therapeutics perspective
  76. Pharmacological Study of A3 Adenosine Receptor agonist (AB Meca) in Xenograft Lung Cancer Model in Mice through In Silico and In Vivo Approach: Targeting TNF-α
  77. Quinoxaline as Ubiquitous Structural Fragment: An Update on the Recent Development of its Green Synthetic Approaches
  78. Protective effects of lycopene against adenine-induced chronic renal failure in rats
  79. Ultrasound-Assisted One-Pot Synthesis of Tetrahydropyrimidne Derivatives through Biginelli Condensation: A Catalyst Free Green Chemistry Approach
  80. Review and Analysis of Massively Registered Clinical Trials of COVID-19 using the Text Mining Approach
  81. Simultaneous quantification of teneligliptin hydrobromide and metformin hydrochloride: An improved HPTLC method with implementation of Plackett-Burman design
  82. Correction to: Comparative Study of the UV-Chemometrics, Ratio Spectra Derivative and HPLC-QbD Methods for the Simultaneous Estimation of Carisoprodol, Paracetamol and Caffeine in Its Triple Combination Formulation CARISOMA
  83. Drug Stereochemistry: A Prodigy For Pharmacology and Drug Development
  84. Classification of Phytotoxins and their Mechanisms of Action
  85. Secondary Metabolites and Toxins of Microbial Origin for the Treatment of Diseases
  86. Comparative Study of the UV Chemometrics, Ratio Spectra Derivative and HPLC-QbD Methods for the Estimation of Their Simultaneous Estimation in Combined Marketed Formulation
  87. Analytical Methods for Simultaneous Estimation of SGLT2 Inhibitor and DPP-4 Inhibitor in their Combination for Treatment of Type 2 Diabetes Mellitus
  88. The β-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimer’s Disease
  89. A Review on the Synthetic Approach of Marinopyrroles: A Natural Anti-tumor Agent from the Ocean
  90. Inhibitory Effect of Artemisinin on Testosterone Propionate Induced Benign Prostatic Hyperplasia
  91. A Library of Thiazolidin‐4‐one Derivatives as Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors: An Attempt To Discover Novel Antidiabetic Agents
  92. APPLICATION OF CHEMOMETRIC METHODS FOR THE DETERMINATION OF CIPROFLOXACIN HYDROCHLORIDE AND PHENAZOPYRIDINE HYDROCHLORIDE IN THEIR PHARMACEUTICAL DOSAGE FORM
  93. In Silico Analysis and Molecular Docking Studies of Novel 6,7-dihydropyrano [2,3-d] pyrimidin-5-one Derivatives as Human Epidermal Growth Factor Receptor 2 (HER2) and Epidermal Growth Factor Receptor (EGFR) Inhibitors
  94. Stability-indicating Analytical Method Development using Quality by Design Approach for Simultaneous Estimation of Ezetimibe and Glimepiride
  95. Assessing adequacy of emergency provider documentation among interhospital transferred patients with acute aortic dissection
  96. Molecular Docking, In-Silico ADMET Study and Development of 1,6- Dihydropyrimidine Derivative as Protein Tyrosine Phosphatase Inhibitor: An Approach to Design and Develop Antidiabetic Agents
  97. Molecular Docking, Synthesis and Biological Evaluation of Sulphonylureas/ Guanidine Derivatives as Promising Antidiabetic Agent
  98. Role of Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Addiction and Related Disorders: A Systematic Review
  99. Stability Indicating Reverse Phase HPLC Method for Estimation of Rifampicin and Piperine in Pharmaceutical Dosage Form
  100. STRUCTURE BASED DRUG DESIGNING, SCORING, AND SYNTHESIS OF SOME SUBSTITUTED SULPHONYLUREAS/GUANIDINE -BASED DERIVATIVES AS HYPOGLYCEMIC AGENTS
  101. Molecular Docking and In Silico ADMET Study Reveals Flavonoids as a Potential Inhibitor of Aromatase
  102. SYNTHESIS OF FLAVONES FROM 2-HYDROXY ACETOPHENONE AND AROMATIC ALDEHYDE DERIVATIVES BY CONVENTIONAL METHODS AND GREEN CHEMISTRY APPROACH
  103. Chemometric Assisted Spectrophotometric Methods for Simultaneous Determination of Paracetamol and Tolperisone Hydrochloride in Pharmaceutical Dosage Form
  104. Chemometric assisted spectrophotometric methods for the simultaneous determination of Rifampicin and Piperine in bulk and capsule