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  1. Curcumin Induces a Fatal Energetic Impairment in Tumor Cells in Vitro and in Vivo by Inhibiting ATP-synthase Activity

    Article • Carcinogenesis, May 2018, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  2. Molecular evolution of colorectal cancer: from multistep carcinogenesis to the big bang

    Article • Cancer and Metastasis Reviews, March 2016, Springer Science + Business Media

    Dr Ulrich Pfeffer

  3. Healing cells

    Article • Scientific Reports, November 2015, Nature

    Dr Ulrich Pfeffer

  4. Potential Role of Soluble c-Met as a New Candidate Biomarker of Metastatic Uveal Melanoma

    Article • JAMA Ophthalmology, September 2015, American Medical Association (AMA)

    Dr Ulrich Pfeffer

  5. IGF1 regulates PKM2 function through Akt phosphorylation

    Article • Cell Cycle, March 2015, Taylor & Francis

    Dr Ulrich Pfeffer

  6. Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway

    Article • Journal of Translational Medicine, January 2015, Springer Science + Business Media

    Dr Ulrich Pfeffer

  7. Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I–III Non-Small Cell Lung Cancer

    Article • Disease Markers, January 2015, Hindawi Publishing Corporation

    Dr Ulrich Pfeffer

  8. ADAM10 correlates with uveal melanoma metastasis and promotes in vitro invasion

    Article • Pigment Cell & Melanoma Research, September 2014, Wiley

    Dr Francesco Spagnolo, Dr Ulrich Pfeffer

  9. Curcumin: Towards molecularly targeted chemoprevention of cancer

    Article • New Horizons in Translational Medicine, September 2014, Elsevier

    Dr Ulrich Pfeffer

  10. Exogenous Hormonal Regulation in Breast Cancer Cells by Phytoestrogens and Endocrine Disruptors

    Article • Current Medicinal Chemistry, February 2014, Bentham Science Publishers

    Dr Ulrich Pfeffer

  11. Endocrine Disruptor Agent Nonyl Phenol Exerts An Estrogen-like Transcriptional Activity on Estrogen Receptor Positive Breast Cancer Cells

    Article • Current Medicinal Chemistry, January 2014, Bentham Science Publishers

    Dr Ulrich Pfeffer

  12. Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel

    Article • Cancer and Metastasis Reviews, January 2014, Springer Science + Business Media

    Dr Ulrich Pfeffer

  13. miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2

    Article • Molecular Oncology, January 2014, Wiley

    Dr Ulrich Pfeffer

  14. Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma

    Article • British Journal of Cancer, January 2014, Nature

    Dr Ulrich Pfeffer

  15. Paradoxic effects of metformin on endothelial cells and angiogenesis

    Article • Carcinogenesis, January 2014, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  16. Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer

    Article • Cell Cycle, November 2013, Taylor & Francis

    Dr Ulrich Pfeffer

  17. Evidence of epidermal growth factor receptor expression in uveal melanoma: Inhibition of epidermal growth factor-mediated signalling by Gefitinib and Cetuximab triggered antibody-dependent cellular cytotoxicity

    Article • European Journal of Cancer, October 2013, Elsevier

    Dr Ulrich Pfeffer

  18. Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II

    Article • Scientific Reports, June 2013, Nature

    Dr Ulrich Pfeffer

  19. Metformin Temporal and Localized Effects on Gut Glucose Metabolism Assessed Using 18F-FDG PET in Mice

    Article • Journal of Nuclear Medicine, January 2013, Society of Nuclear Medicine

    Dr Ulrich Pfeffer

  20. Cancer Genomics

    Article • January 2013, Springer Science + Business Media

    Dr Ulrich Pfeffer

  21. Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients

    Article • Molecular Cancer, January 2013, Springer Science + Business Media

    Dr Ulrich Pfeffer

  22. Journal Club

    Article • Forschende Komplementärmedizin / Research in Complementary Medicine, January 2013, Karger Publishers

    Dr Ulrich Pfeffer

  23. Breast Cancer Genomics: From Portraits to Landscapes

    Article • December 2012, Springer Science + Business Media

    Dr Ulrich Pfeffer

  24. Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2

    Article • Carcinogenesis, October 2012, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  25. Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125

    Article • Biochemical Pharmacology, September 2012, Elsevier

    Dr Ulrich Pfeffer

  26. Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells

    Article • BMC Cancer, August 2012, Springer Science + Business Media

    Dr Ulrich Pfeffer

  27. Mda-9/Syntenin Is Expressed in Uveal Melanoma and Correlates with Metastatic Progression

    Article • PLoS ONE, January 2012, PLOS

    Dr Ulrich Pfeffer

  28. Interplay between histopathological alterations, cigarette smoke and chemopreventive agents in defining microRNA profiles in mouse lung

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, December 2011, Elsevier

    Dr Ulrich Pfeffer

  29. A prognostic multigene classifier for squamous cell carcinomas of the larynx

    Article • Cancer Letters, August 2011, Elsevier

    Dr Ulrich Pfeffer

  30. Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling

    Article • AJP Cell Physiology, July 2011, American Physiological Society

    Dr Ulrich Pfeffer

  31. Development of Resistance towards Artesunate in MDA-MB-231 Human Breast Cancer Cells

    Article • PLoS ONE, May 2011, PLOS

    Dr Ulrich Pfeffer

  32. PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma

    Article • PLoS ONE, October 2010, PLOS

    Dr Ulrich Pfeffer

  33. Demethyl fruticulin A (SCO-1) causes apoptosis by inducing reactive oxygen species in mitochondria

    Article • Journal of Cellular Biochemistry, August 2010, Wiley

    Dr Ulrich Pfeffer

  34. Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs

    Article • Clinical & Experimental Metastasis, April 2010, Springer Science + Business Media

    Dr Ulrich Pfeffer

  35. Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung

    Article • Carcinogenesis, February 2010, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  36. In vivo growth inhibition of head and neck squamous cell carcinoma by the Interferon-inducible gene IFI16

    Article • Cancer Letters, January 2010, Elsevier

    Professor Marco De Andrea, Dr Ulrich Pfeffer

  37. Novel aspects for the application of Curcumin in chemoprevention of various cancers

    Article • January 2010, Frontiers in Bioscience

    Dr Ulrich Pfeffer

  38. Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin

    Article • Cellular Physiology and Biochemistry, January 2010, Karger Publishers

    Dr Ulrich Pfeffer

  39. CXCL12/SDF1 expression by breast cancers is an independent prognostic marker of disease-free and overall survival

    Article • European Journal of Cancer, September 2009, Elsevier

    Dr Ulrich Pfeffer

  40. Prediction of breast cancer metastasis by genomic profiling: where do we stand?

    Article • Clinical & Experimental Metastasis, March 2009, Springer Science + Business Media

    Dr Ulrich Pfeffer

  41. Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke

    Article • AJP Lung Cellular and Molecular Physiology, March 2009, American Physiological Society

    Dr Ulrich Pfeffer, Fabio Sallustio

  42. Interferon-  counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer

    Article • Carcinogenesis, February 2009, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  43. Survival Online: a web-based service for the analysis of correlations between gene expression and clinical and follow-up data

    Article • BMC Bioinformatics, January 2009, Springer Science + Business Media

    Dr Ulrich Pfeffer

  44. Overexpression of the ATP binding cassette gene ABCA1 determines resistance to Curcumin in M14 melanoma cells

    Article • Molecular Cancer, January 2009, Springer Science + Business Media

    Dr Ulrich Pfeffer

  45. TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

    Article • Science, October 2008, American Association for the Advancement of Science

    Dr Ulrich Pfeffer

  46. Endothelial Cell Aging and Apoptosis in Prevention and Disease: E-Selectin Expression and Modulation As A Model

    Article • Current Pharmaceutical Design, January 2008, Bentham Science Publishers

    Dr Ulrich Pfeffer

  47. HER2 Status and Efficacy of Adjuvant Anthracyclines in Early Breast Cancer: A Pooled Analysis of Randomized Trials

    Article • JNCI Journal of the National Cancer Institute, December 2007, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  48. Metastasis signatures: genes regulating tumor–microenvironment interactions predict metastatic behavior

    Article • Cancer and Metastasis Reviews, November 2007, Springer Science + Business Media

    Dr Ulrich Pfeffer

  49. Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NF B

    Article • Carcinogenesis, November 2007, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  50. The Chemopreventive Polyphenol Curcumin Prevents Hematogenous Breast Cancer Metastases in Immunodeficient Mice

    Article • Cellular Physiology and Biochemistry, January 2007, Karger Publishers

    Dr Ulrich Pfeffer

  51. Biological assays and genomic analysis reveal lipoic acid modulation of endothelial cell behavior and gene expression

    Article • Carcinogenesis, November 2006, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  52. A New Tumor Suppressor Gene: Invasion, Metastasis, and Angiogenesis as Potential Key Targets

    Article • JNCI Journal of the National Cancer Institute, June 2006, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  53. Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins

    Article • The Pharmacogenomics Journal, January 2006, Nature

    Dr Ulrich Pfeffer

  54. Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: Microarray gene expression analyses

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, December 2005, Elsevier

    Dr Ulrich Pfeffer

  55. The Transforming Growth Factor-  Family Members Bone Morphogenetic Protein-2 and Macrophage Inhibitory Cytokine-1 as Mediators of the Antiangiogenic Activity of N-(4-Hydroxyphenyl)Retinamide

    Article • Clinical Cancer Research, June 2005, American Association for Cancer Research (AACR)

    Dr Ulrich Pfeffer

  56. Transcriptional control of cell density dependent regulation of matrix metalloproteinase and TIMP expression in breast cancer cell lines

    Article • Thrombosis and Haemostasis, March 2005, Schattauer GmbH

    Dr Ulrich Pfeffer

  57. Article • Retrovirology, January 2005, Springer Science + Business Media

    Dr Ulrich Pfeffer

  58. Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate

    Article • Biochemical Pharmacology, December 2004, Elsevier

    Dr Ulrich Pfeffer

  59. α-Lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis

    Article • Journal of Neuroimmunology, March 2004, Elsevier

    Dr Ulrich Pfeffer

  60. Re: Microarray Studies Challenge Theories of Metastasis

    Article • JNCI Journal of the National Cancer Institute, June 2003, Oxford University Press (OUP)

    Dr Ulrich Pfeffer

  61. Somatostatin Inhibits Tumor Angiogenesis and Growth via Somatostatin Receptor-3-Mediated Regulation of Endothelial Nitric Oxide Synthase and Mitogen-Activated Protein Kinase Activities

    Article • Endocrinology, April 2003, Endocrine Society

    Dr Ulrich Pfeffer, Professor Tullio Florio

  62. Human Chorionic Gonadotropin Inhibits Kaposi's Sarcoma Associated Angiogenesis, Matrix Metalloprotease Activity, and Tumor Growth

    Article • Endocrinology, August 2002, Endocrine Society

    Dr Ulrich Pfeffer

  63. The androgen receptor CAG repeat: a modifier of carcinogenesis?

    Article • Molecular and Cellular Endocrinology, July 2002, Elsevier

    Dr Ulrich Pfeffer

  64. Kaposis Sarcoma and Human Chorionic Gonadotropin: Mechanisms, Moieties and Mysteries

    Article • Biological Chemistry, January 2002, De Gruyter

    Dr Ulrich Pfeffer

  65. Inhibition of Tumor Angiogenesis by Angiostatin: From Recombinant Protein to Gene Therapy

    Article • Endothelium, January 2002, Taylor & Francis

    Dr Ulrich Pfeffer

  66. Are there CAG repeat expansion-related disorders outside the central nervous system?

    Article • Brain Research Bulletin, November 2001, Elsevier

    Dr Ulrich Pfeffer

  67. Somatic alterations of the androgen receptor CAG repeat in human colon cancer delineate a novel mutation pathway independent of microsatellite instability

    Article • Cancer Genetics and Cytogenetics, November 2000, Elsevier

    Dr Ulrich Pfeffer

  68. [5] Use of quantitative polymerase chain reaction to study retinoid receptor expression

    Article • January 1997, Elsevier

    Dr Ulrich Pfeffer

  69. Estrogen Receptor mRNA Variants.

    Article • Annals of the New York Academy of Sciences, April 1996, Wiley

    Dr Ulrich Pfeffer

  70. Alternative splicing of the estrogen receptor primary transcript normally occurs in estrogen receptor positive tissues and cell lines

    Article • The Journal of Steroid Biochemistry and Molecular Biology, January 1996, Elsevier

    Dr Ulrich Pfeffer

  71. Growth of LNCaP human prostate cancer cells is stimulated by estradiol via its own receptor

    Article • Endocrinology, May 1995, Endocrine Society

    Dr Ulrich Pfeffer

  72. An Improved RT-PCR Protocol for the Quantitation of Human Retinoic Acid Receptor RNA

    Article • Experimental Cell Research, March 1994, Elsevier

    Dr Ulrich Pfeffer

  73. Quantitative analysis of mitotic and early-G1 cells using monoclonal antibodies against the AF-2 protein

    Article • Cytometry, January 1993, Wiley

    Dr Ulrich Pfeffer

  74. Regulation of plasma retinol binding protein secretion in human HepG2 cells

    Article • Experimental Cell Research, June 1992, Elsevier

    Dr Ulrich Pfeffer

  75. Lineage infidelity and expression of melanocytic markers in human breast cancer

    Article • International Journal of Oncology, January 1992, Spandidos Publications

    Dr Ulrich Pfeffer

  76. Cell cycle dependent alterations of chromatin structure in situ as revealed by the accessibility of the nuclear protein AF-2 to monoclonal antibodies

    Article • Journal of Cellular Physiology, December 1991, Wiley

    Dr Ulrich Pfeffer

  77. A novel protein related to cell cycle-dependent alterations of chromatin structure

    Article • Experimental Cell Research, April 1991, Elsevier

    Dr Ulrich Pfeffer

  78. Histone acetylation: Recent approaches to a basic mechanism of genome organization

    Article • International Journal of Biochemistry, January 1991, Elsevier

    Dr Ulrich Pfeffer

  79. MoAbs against cell cycle related antigens

    Article • European Journal of Cancer and Clinical Oncology, January 1991, Elsevier

    Dr Ulrich Pfeffer

  80. Histone hyperacetylation is induced in chick erythrocyte nuclei during reactivation in heterokaryons*1

    Article • Experimental Cell Research, September 1988, Elsevier

    Dr Ulrich Pfeffer

  81. Nucleosomal structure as probed by H3 histone thiol reactivity

    Article • Cell Biochemistry and Biophysics, February 1987, Springer Science + Business Media

    Dr Ulrich Pfeffer