All Stories

  1. Plasma N-glycan signature as biomarker for primary open angle glaucoma

    Article • Experimental Eye Research, September 2025, Elsevier

    Prof. Tsz Kin Ng

  2. Detection rate of cataract-related gene variants in sporadic childhood cataract patients in Southern China

    Article • American Journal of Ophthalmology, August 2025, Elsevier

    Prof. Tsz Kin Ng

  3. The Profile of Retinal Ganglion Cell Death and Cellular Senescence in Mice with Aging

    Article • International Journal of Molecular Sciences, June 2025, MDPI AG

    Prof. Tsz Kin Ng

  4. Development and validation of a 3-D deep learning system for diabetic macular oedema classification on optical coherence tomography images

    Article • BMJ Open, May 2025, BMJ

    Prof. Tsz Kin Ng

  5. Cellular senescence mediates retinal ganglion cell survival regulation post‐optic nerve crush injury

    Article • Cell Proliferation, July 2024, Wiley

    Prof. Tsz Kin Ng

  6. Profile of Lipoprotein Subclasses in Chinese Primary Open-Angle Glaucoma Patients

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Prof. Tsz Kin Ng

  7. Evaluation of Myocilin Variant Protein Structures Modeled by AlphaFold2

    Article • Biomolecules, December 2023, MDPI AG

    Prof. Tsz Kin Ng

  8. Longitudinal in vivo evaluation of retinal ganglion cell complex layer and dendrites in mice with experimental autoimmune encephalomyelitis

    Article • Experimental Eye Research, December 2023, Elsevier

    Prof. Tsz Kin Ng

  9. Allergy Test Dosage of Fluorescein Detects Diabetic Retinopathy Changes in Fundus Fluorescein Angiography

    Article • Diagnostics, November 2023, MDPI AG

    Prof. Tsz Kin Ng

  10. Association of body mass index and PXDNL gene variants with acute primary angle closure in southern Chinese population

    Article • Heliyon, November 2023, Elsevier

    Prof. Tsz Kin Ng

  11. Primary open-angle glaucoma risk prediction with ABCA1 and LOC102723944 variants and their genotype–phenotype correlations in southern Chinese population

    Article • Molecular Genetics and Genomics, July 2023, Springer Science + Business Media

    Prof. Tsz Kin Ng

  12. Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy

    Article • Journal of Diabetes, July 2023, Wiley

    Prof. Tsz Kin Ng

  13. Green tea extract enhances retinal ganglion cell survival and axonal regeneration in rats with optic nerve injury

    Article • The Journal of Nutritional Biochemistry, July 2023, Elsevier

    Prof. Tsz Kin Ng

  14. Green Tea Catechins as Therapeutic Antioxidants for Glaucoma Treatment

    Article • Antioxidants, June 2023, MDPI AG

    Prof. Tsz Kin Ng

  15. Retinal transcriptome of neonatal mice after optic nerve injury

    Article • PLOS One, May 2023, PLOS

    Prof. Tsz Kin Ng

  16. Azelaic acid and guanosine in tears improve discrimination of proliferative from non-proliferative diabetic retinopathy in type-2 diabetes patients: A tear metabolomics study

    Article • Heliyon, May 2023, Elsevier

    Prof. Tsz Kin Ng

  17. Longitudinal and simultaneous profiling of 11 modes of cell death in mouse retina post-optic nerve injury

    Article • Experimental Eye Research, September 2022, Elsevier

    Prof. Tsz Kin Ng

  18. Diagnostic Accuracy of Wide-Field Digital Retinal Images in Retinopathy of Prematurity Detection: Systematic Review and Meta-Analysis

    Article • Current Eye Research, April 2022, Taylor & Francis

    Prof. Tsz Kin Ng

  19. Hydroxychloroquine treatment on SARS-CoV-2 receptor ACE2, TMPRSS2 and NRP1 expression in human primary pterygium and conjunctival cells

    Article • Experimental Eye Research, January 2022, Elsevier

    Prof. Tsz Kin Ng

  20. Diversified Treatment Options of Adult Stem Cells for Optic Neuropathies

    Article • Cell Transplantation, January 2022, SAGE Publications

    Prof. Tsz Kin Ng

  21. Green Tea Catechins Attenuate Human Primary Pterygium Cell Survival and Migration Via Modulation of ERK p42/p44 and p38 Pathways

    Article • Journal of Agricultural and Food Chemistry, October 2021, American Chemical Society (ACS)

    Prof. Tsz Kin Ng

  22. Agonist of growth hormone–releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury

    Article • Proceedings of the National Academy of Sciences, July 2021, Proceedings of the National Academy of Sciences

    Prof. Tsz Kin Ng

  23. CXCL5/CXCR2 modulates inflammation-mediated neural repair after optic nerve injury

    Article • Experimental Neurology, July 2021, Elsevier

    Prof. Tsz Kin Ng

  24. Corneal curvature-associated MTOR variant differentiates mild myopia from high myopia in Han Chinese population

    Article • Ophthalmic Genetics, May 2021, Taylor & Francis

    Prof. Tsz Kin Ng

  25. Whole exome sequencing analysis identifies novel Stargardt disease-related gene mutations in Chinese Stargardt disease and retinitis pigmentosa patients

    Article • Eye, April 2021, Springer Science + Business Media

    Prof. Tsz Kin Ng

  26. Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis

    Article • BMC Ophthalmology, February 2021, Springer Science + Business Media

    Prof. Tsz Kin Ng

  27. CFH I62V as a Putative Genetic Marker for Posner-Schlossman Syndrome

    Article • Frontiers in Immunology, February 2021, Frontiers

    Prof. Tsz Kin Ng

  28. Peritoneal macrophages attenuate retinal ganglion cell survival and neurite outgrowth

    Article • Neural Regeneration Research, January 2021, Medknow

    Prof. Tsz Kin Ng

  29. Association of 24-Hour Intraocular Pressure Fluctuation With Corneal Hysteresis and Axial Length in Untreated Chinese Primary Open-Angle Glaucoma Patients

    Article • Translational Vision Science & Technology, November 2020, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  30. Seasonal variations and climatic factors on acute primary angle‐closure admission in southern China: a 5‐year hospital‐based retrospective study

    Article • Acta Ophthalmologica, October 2020, Wiley

    Prof. Tsz Kin Ng

  31. MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells

    Article • Molecular Therapy — Nucleic Acids, September 2020, Elsevier

    Prof. Tsz Kin Ng

  32. Complex effect of continuous curcumin exposure on human bone marrow‐derived mesenchymal stem cell regenerative properties through matrix metalloproteinase regulation

    Article • Basic & Clinical Pharmacology & Toxicology, August 2020, Wiley

    Prof. Tsz Kin Ng

  33. Expression of SARS-CoV-2 receptor ACE2 and TMPRSS2 in human primary conjunctival and pterygium cell lines and in mouse cornea

    Article • Eye, May 2020, Springer Science + Business Media

    Prof. Tsz Kin Ng

  34. Longitudinal evaluation of immediate inflammatory responses after intravitreal AAV2 injection in rats by optical coherence tomography

    Article • Experimental Eye Research, April 2020, Elsevier

    Prof. Tsz Kin Ng

  35. Association of the CAV1 ‐ CAV2 locus with normal‐tension glaucoma in Chinese and Japanese

    Article • Clinical and Experimental Ophthalmology, March 2020, Wiley

    Prof. Tsz Kin Ng

  36. Signaling mechanisms of growth hormone-releasing hormone receptor in LPS-induced acute ocular inflammation

    Article • Proceedings of the National Academy of Sciences, March 2020, Proceedings of the National Academy of Sciences

    Prof. Tsz Kin Ng

  37. Attenuated regenerative properties in human periodontal ligament–derived stem cells of older donor ages with shorter telomere length and lower SSEA4 expression

    Article • Cell and Tissue Research, February 2020, Springer Science + Business Media

    Prof. Tsz Kin Ng

  38. COL2A1 protective variant reduces sporadic rhegmatogenous retinal detachment severity

    Article • Experimental Eye Research, February 2020, Elsevier

    Prof. Tsz Kin Ng

  39. Changes in corneal biomechanics during pregnancy in Chinese healthy female

    Article • European Journal of Ophthalmology, January 2020, SAGE Publications

    Prof. Tsz Kin Ng

  40. Vision improvement in severe acute isolated optic neuritis after plasma exchange treatment in Chinese population: a prospective case series study

    Article • Therapeutic Advances in Neurological Disorders, January 2020, SAGE Publications

    Prof. Tsz Kin Ng

  41. Transplantation of Retinal Ganglion Cells Derived from Male Germline Stem Cell as a Potential Treatment to Glaucoma

    Article • Stem Cells and Development, October 2019, Mary Ann Liebert Inc

    Prof. Tsz Kin Ng

  42. Genotype–phenotype correlation and interaction of 4q25, 15q14 and MIPEP variants with myopia in southern Chinese population

    Article • British Journal of Ophthalmology, October 2019, BMJ

    Prof. Tsz Kin Ng

  43. Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration

    Article • Experimental Eye Research, October 2019, Elsevier

    Prof. Tsz Kin Ng

  44. Green Tea Extract Ameliorates Ischemia-Induced Retinal Ganglion Cell Degeneration in Rats

    Article • Oxidative Medicine and Cellular Longevity, July 2019, Hindawi Publishing Corporation

    Prof. Tsz Kin Ng

  45. Whole exome sequencing identifies novel USH2A mutations and confirms Usher syndrome 2 diagnosis in Chinese retinitis pigmentosa patients

    Article • Scientific Reports, April 2019, Springer Science + Business Media

    Prof. Tsz Kin Ng, Haoyu Chen

  46. Growth hormone-releasing hormone receptor mediates cytokine production in ciliary and iris epithelial cells during LPS-induced ocular inflammation

    Article • Experimental Eye Research, April 2019, Elsevier

    Prof. Tsz Kin Ng

  47. Caveolin‐1 regulates human trabecular meshwork cell adhesion, endocytosis, and autophagy

    Article • Journal of Cellular Biochemistry, March 2019, Wiley

    Prof. Tsz Kin Ng

  48. Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation by inhibiting Th17-associated pro-inflammatory gene expression

    Article • Scientific Reports, February 2019, Springer Science + Business Media

    Prof. Tsz Kin Ng

  49. MicroRNA‐132 directs human periodontal ligament‐derived neural crest stem cell neural differentiation

    Article • Journal of Tissue Engineering and Regenerative Medicine, December 2018, Wiley

    Prof. Tsz Kin Ng

  50. Casein kinase-II inhibition promotes retinal ganglion cell survival and axonal regeneration

    Article • Experimental Eye Research, December 2018, Elsevier

    Prof. Tsz Kin Ng

  51. Intravitreal Injection of Hydrogen Peroxide Induces Acute Retinal Degeneration, Apoptosis, and Oxidative Stress in Mice

    Article • Oxidative Medicine and Cellular Longevity, November 2018, Hindawi Publishing Corporation

    Haoyu Chen, Prof. Tsz Kin Ng

  52. Metabolomics of Green-Tea Catechins on Vascular-Endothelial-Growth-Factor-Stimulated Human-Endothelial-Cell Survival

    Article • Journal of Agricultural and Food Chemistry, November 2018, American Chemical Society (ACS)

    Prof. Tsz Kin Ng

  53. Notch Signaling Activation Enhances Human Adipose-Derived Stem Cell Retinal Differentiation

    Article • Stem Cells International, October 2018, Hindawi Publishing Corporation

    Prof. Tsz Kin Ng

  54. p53 inhibition by MDM2 in human pterygium

    Article • Experimental Eye Research, October 2018, Elsevier

    Prof. Tsz Kin Ng

  55. Continuous exposure of nicotine and cotinine retards human primary pterygium cell proliferation and migration

    Article • Journal of Cellular Biochemistry, September 2018, Wiley

    Prof. Tsz Kin Ng

  56. The Evolving Story of Pterygium

    Article • Cornea, September 2018, Wolters Kluwer Health

    Prof. Tsz Kin Ng

  57. Cellular Proliferation and Migration of Human Pterygium Cells

    Article • Cornea, June 2018, Wolters Kluwer Health

    Prof. Tsz Kin Ng

  58. Human Periodontal Ligament-Derived Stem Cells Promote Retinal Ganglion Cell Survival and Axon Regeneration After Optic Nerve Injury

    Article • Stem Cells, March 2018, Wiley

    Prof. Tsz Kin Ng

  59. Histological and microRNA Signatures of Corneal Epithelium in Keratoconus

    Article • Journal of Refractive Surgery, March 2018, SLACK, Inc.

    Prof. Tsz Kin Ng

  60. Green tea extract attenuates LPS-induced retinal inflammation in rats

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Prof. Tsz Kin Ng

  61. Stem cell therapy for retinal ganglion cell degeneration

    Article • Neural Regeneration Research, January 2018, Medknow

    Prof. Tsz Kin Ng

  62. Quantitative Characterization of Autoimmune Uveoretinitis in an Experimental Mouse Model

    Article • Investigative Ophthalmology & Visual Science, August 2017, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  63. Disruption of retinal pigment epithelial cell properties under the exposure of cotinine

    Article • Scientific Reports, June 2017, Springer Science + Business Media

    Prof. Tsz Kin Ng

  64. Elevated angiopoietin 2 in aqueous of patients with neovascular age related macular degeneration correlates with disease severity at presentation

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Prof. Tsz Kin Ng

  65. AAV-mediated transfer of RhoA shRNA and CNTF promotes retinal ganglion cell survival and axon regeneration

    Article • Neuroscience, February 2017, Elsevier

    Prof. Tsz Kin Ng

  66. Conventional Versus Inverted Side-cut Flaps for Femtosecond Laser-Assisted LASIK: Laboratory and Clinical Evaluation

    Article • Journal of Refractive Surgery, February 2017, SLACK, Inc.

    Prof. Tsz Kin Ng

  67. Continuous exposure to non-lethal doses of sodium iodate induces retinal pigment epithelial cell dysfunction

    Article • Scientific Reports, November 2016, Springer Science + Business Media

    Prof. Tsz Kin Ng

  68. Protective effects of an HTRA1 insertion–deletion variant against age-related macular degeneration in the Chinese populations

    Article • Laboratory Investigation, November 2016, Nature

    Haoyu Chen, Prof. Tsz Kin Ng

  69. Green tea catechins are potent anti-oxidants that ameliorate sodium iodate-induced retinal degeneration in rats

    Article • Scientific Reports, July 2016, Springer Science + Business Media

    Prof. Tsz Kin Ng

  70. HTRA1 promoter variant differentiates polypoidal choroidal vasculopathy from exudative age-related macular degeneration

    Article • Scientific Reports, June 2016, Nature

    Haoyu Chen, Prof. Tsz Kin Ng

  71. Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts

    Article • PLoS Genetics, June 2016, PLOS

    Haoyu Chen, Prof. Tsz Kin Ng

  72. Spontaneous neural activity in the primary visual cortex of retinal degenerated rats

    Article • Neuroscience Letters, June 2016, Elsevier

    Prof. Tsz Kin Ng

  73. Electrophysiology Alterations in Primary Visual Cortex Neurons of Retinal Degeneration (S334ter-line-3) Rats

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Prof. Tsz Kin Ng

  74. Genetics of Bietti Crystalline Dystrophy

    Article • Asia-Pacific Journal of Ophthalmology, January 2016, Asia Pacific Academy of Ophthalmology

    Prof. Tsz Kin Ng

  75. Variations in the Obesity Gene “LEPR” Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis

    Article • Journal of Diabetes Research, January 2016, Hindawi Publishing Corporation

    Prof. Tsz Kin Ng

  76. Transdifferentiation of periodontal ligament-derived stem cells into retinal ganglion-like cells and its microRNA signature

    Article • Scientific Reports, November 2015, Springer Science + Business Media

    Prof. Tsz Kin Ng

  77. Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials

    Article • Scientific Reports, January 2015, Springer Science + Business Media

    Prof. Tsz Kin Ng

  78. Antagonist of GH-releasing hormone receptors alleviates experimental ocular inflammation

    Article • Proceedings of the National Academy of Sciences, December 2014, Proceedings of the National Academy of Sciences

    Haoyu Chen, Prof. Tsz Kin Ng

  79. FPR1 interacts with CFH, HTRA1 and smoking in exudative age-related macular degeneration and polypoidal choroidal vasculopathy

    Article • Eye, October 2014, Springer Science + Business Media

    Prof. Tsz Kin Ng

  80. Assessing Sodium Iodate–Induced Outer Retinal Changes in Rats Using Confocal Scanning Laser Ophthalmoscopy and Optical Coherence Tomography

    Article • Investigative Ophthalmology & Visual Science, March 2014, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  81. Progress of mesenchymal stem cell therapy for neural and retinal diseases

    Article • World Journal of Stem Cells, January 2014, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Prof. Tsz Kin Ng

  82. Letter to the Editor Regarding “Virtual Screening of Natural and Synthetic Ligands Against Diabetic Retinopathy by Molecular Interaction With Angiopoietin-2”

    Article • Asia-Pacific Journal of Ophthalmology, January 2014, Asia Pacific Academy of Ophthalmology

    Prof. Tsz Kin Ng

  83. Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy

    Article • Molecular Medicine Reports, October 2013, Spandidos Publications

    Prof. Tsz Kin Ng

  84. Association ofCFHandSERPING1polymorphisms with anterior uveitis

    Article • British Journal of Ophthalmology, August 2013, BMJ

    Prof. Tsz Kin Ng

  85. Nicotine Alters MicroRNA Expression and Hinders Human Adult Stem Cell Regenerative Potential

    Article • Stem Cells and Development, March 2013, Mary Ann Liebert Inc

    Prof. Tsz Kin Ng

  86. Prospects of Stem Cells for Retinal Diseases

    Article • Asia-Pacific Journal of Ophthalmology, January 2013, Asia Pacific Academy of Ophthalmology

    Prof. Tsz Kin Ng

  87. Association ofC2andCFBPolymorphisms with Anterior Uveitis

    Article • Investigative Ophthalmology & Visual Science, July 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  88. Differentiation of Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in theARMS2/HTRA1Locus

    Article • Investigative Ophthalmology & Visual Science, May 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  89. HTRA1 in Age-Related Macular Degeneration

    Article • Asia-Pacific Journal of Ophthalmology, January 2012, Asia Pacific Academy of Ophthalmology

    Prof. Tsz Kin Ng

  90. MicroRNA-145 Regulates Human Corneal Epithelial Differentiation

    Article • PLOS One, June 2011, PLOS

    Prof. Tsz Kin Ng

  91. Interactive Expressions of HtrA1 and VEGF in Human Vitreous Humors and Fetal RPE Cells

    Article • Investigative Ophthalmology & Visual Science, May 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Haoyu Chen, Prof. Tsz Kin Ng

  92. Alterations in Serum Fatty Acid Concentrations and Desaturase Activities in Bietti Crystalline Dystrophy Unaffected byCYP4V2Genotypes

    Article • Investigative Ophthalmology & Visual Science, February 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  93. Multiple Gene Polymorphisms in the Complement Factor H Gene Are Associated with Exudative Age-Related Macular Degeneration in Chinese

    Article • Investigative Ophthalmology & Visual Science, August 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  94. Association ofCTLA-4andIL-13Gene Polymorphisms with Graves’ Disease and Ophthalmopathy in Chinese Children

    Article • Investigative Ophthalmology & Visual Science, June 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  95. HTRA1Variants in Exudative Age-Related Macular Degeneration and Interactions with Smoking andCFH

    Article • Investigative Ophthalmology & Visual Science, June 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng

  96. Genotype–Phenotype Analysis of Bietti’s Crystalline Dystrophy in Patients withCYP4V2Mutations

    Article • Investigative Ophthalmology & Visual Science, November 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Prof. Tsz Kin Ng