All Stories

  1. Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites

    Article • Journal of Medicinal Chemistry, September 2023, American Chemical Society (ACS)

    Tomas Herraiz

  2. Identification, Formation, and Occurrence of Perlolyrine: A β-Carboline Alkaloid with a Furan Moiety in Foods

    Article • Journal of Agricultural and Food Chemistry, August 2023, American Chemical Society (ACS)

    Tomas Herraiz

  3. β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO)

    Article • Molecules, March 2023, MDPI AG

    Tomas Herraiz

  4. Assay of MAO Inhibition by Chromatographic Techniques (HPLC/HPLC-MS)

    Article • September 2022, Springer Science + Business Media

    Tomas Herraiz

  5. Formation, Characterization, and Occurrence of β-Carboline Alkaloids Derived from α-Dicarbonyl Compounds and l-Tryptophan

    Article • Journal of Agricultural and Food Chemistry, July 2022, American Chemical Society (ACS)

    Tomas Herraiz

  6. Occurrence, Formation from d-Fructose and 3-Deoxyglucosone, and Activity of the Carbohydrate-Derived β-Carbolines in Foods

    Article • Journal of Agricultural and Food Chemistry, June 2021, American Chemical Society (ACS)

    Tomas Herraiz

  7. Chloroquine and hydroxychloroquine as antimalarials and antivirals against SARS-CoV-2: The hemin factor

    Article • June 2020, Center for Open Science

    Tomas Herraiz

  8. Antimalarial Quinoline Drugs Inhibit β-Hematin and Increase Free Hemin Catalyzing Peroxidative Reactions and Inhibition of Cysteine Proteases

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Tomas Herraiz

  9. Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against T. brucei and T. congolense

    Article • European Journal of Medicinal Chemistry, April 2018, Elsevier

    Tomas Herraiz

  10. Nitrosative deamination of 2′-deoxyguanosine and DNA by nitrite, and antinitrosating activity of β-carboline alkaloids and antioxidants

    Article • Food and Chemical Toxicology, February 2018, Elsevier

    Tomas Herraiz

  11. Monoamine Oxidase-A Inhibition and Associated Antioxidant Activity in Plant Extracts with Potential Antidepressant Actions

    Article • BioMed Research International, January 2018, Hindawi Publishing Corporation

    Tomas Herraiz

  12. Analysis of monoamine oxidase (MAO) enzymatic activity by high-performance liquid chromatography-diode array detection combined with an assay of oxidation with a peroxidase and its application to MAO inhibitors from foods and plants

    Article • Journal of Chromatography B, January 2018, Elsevier

    Tomas Herraiz

  13. Identification, occurrence and activity of quinazoline alkaloids in Peganum harmala

    Article • Food and Chemical Toxicology, May 2017, Elsevier

    Tomas Herraiz

  14. N-methyltetrahydropyridines and pyridinium cations as toxins and comparison with naturally-occurring alkaloids

    Article • Food and Chemical Toxicology, November 2016, Elsevier

    Tomas Herraiz

  15. Hydroxyl radical reactions and the radical scavenging activity of β-carboline alkaloids

    Article • Food Chemistry, April 2015, Elsevier

    Tomas Herraiz

  16. A New NonpolarN-Hydroxy Imidazoline Lead Compound with Improved Activity in a Murine Model of Late-Stage Trypanosoma brucei brucei Infection Is Not Cross-Resistant with Diamidines

    Article • Antimicrobial Agents and Chemotherapy, November 2014, ASM Journals

    Tomas Herraiz

  17. Naturally-occurring tetrahydro-β-carboline alkaloids derived from tryptophan are oxidized to bioactive β-carboline alkaloids by heme peroxidases

    Article • Biochemical and Biophysical Research Communications, August 2014, Elsevier

    Tomas Herraiz

  18. The new psychoactive substance, 5-IT, is an inhibitor of human monoamine oxidase (MAO).

    Article • Drug Testing and Analysis, September 2013, Wiley

    Tomas Herraiz

  19. Metabolite Profile Resulting from the Activation/Inactivation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 2-Methyltetrahydro-β-carboline by Oxidative Enzymes

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Tomas Herraiz

  20. Evaluation of the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to toxic pyridinium cations by monoamine oxidase (MAO) enzymes and its use to search for new MAO inhibitors and protective agents

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, October 2011, Taylor & Francis

    Tomas Herraiz

  21. Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors

    Article • Food and Chemical Toxicology, August 2011, Elsevier

    Tomas Herraiz

  22. β-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO)

    Article • Food and Chemical Toxicology, March 2010, Elsevier

    Tomas Herraiz

  23. Characterization of a Nitroreductase with Selective Nitroreduction Properties in the Food and Intestinal Lactic Acid Bacterium Lactobacillus plantarum WCFS1

    Article • Journal of Agricultural and Food Chemistry, November 2009, American Chemical Society (ACS)

    Tomas Herraiz

  24. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO)

    Article • Free Radical Research, January 2009, Taylor & Francis

    Tomas Herraiz

  25. Oxidative Metabolism of the Bioactive and Naturally Occurring β-Carboline Alkaloids, Norharman and Harman, by Human Cytochrome P450 Enzymes

    Article • Chemical Research in Toxicology, November 2008, American Chemical Society (ACS)

    Tomas Herraiz

  26. Fingerprint analysis of thermolytic decarboxylation of tryptophan to tryptamine catalyzed by natural oils

    Article • Journal of Chromatography A, November 2008, Elsevier

    Tomas Herraiz

  27. Identification and Occurrence of β-Carboline Alkaloids in Raisins and Inhibition of Monoamine Oxidase (MAO)

    Article • Journal of Agricultural and Food Chemistry, October 2007, American Chemical Society (ACS)

    Tomas Herraiz

  28. N-Methyltetrahydro-β-carboline analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic β-carbolinium cations by heme peroxidases

    Article • Biochemical and Biophysical Research Communications, April 2007, Elsevier

    Tomas Herraiz

  29. Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated β-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6

    Article • Toxicology and Applied Pharmacology, November 2006, Elsevier

    Tomas Herraiz

  30. Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by β-carboline alkaloids occurring in foods and plants

    Article • Journal of Chromatography A, July 2006, Elsevier

    Tomas Herraiz

  31. Human monoamine oxidase enzyme inhibition by coffee and β-carbolines norharman and harman isolated from coffee

    Article • Life Sciences, January 2006, Elsevier

    Tomas Herraiz

  32. Human monoamine oxidase is inhibited by tobacco smoke: β-carboline alkaloids act as potent and reversible inhibitors

    Article • Biochemical and Biophysical Research Communications, January 2005, Elsevier

    Tomas Herraiz

  33. Relative exposure toβ-carbolines norharman and harman from foods and tobacco smoke

    Article • Food Additives & Contaminants, November 2004, Taylor & Francis

    Tomas Herraiz

  34. Identification and Occurrence of Tryptamine- and Tryptophan-Derived Tetrahydro-β-carbolines in Commercial Sausages

    Article • Journal of Agricultural and Food Chemistry, May 2004, American Chemical Society (ACS)

    Tomas Herraiz

  35. Endogenous and Dietary Indoles: A Class of Antioxidants and Radical Scavengers in the ABTS Assay

    Article • Free Radical Research, March 2004, Taylor & Francis

    Tomas Herraiz

  36. Tetrahydro-β-carboline Alkaloids Occur in Fruits and Fruit Juices. Activity as Antioxidants and Radical Scavengers

    Article • Journal of Agricultural and Food Chemistry, November 2003, American Chemical Society (ACS)

    Tomas Herraiz

  37. Article • Pharmacogenetics, June 2003, Wolters Kluwer Health

    Tomas Herraiz

  38. l-Tryptophan Reacts with Naturally Occurring and Food-Occurring Phenolic Aldehydes To Give Phenolic Tetrahydro-β-carboline Alkaloids:  Activity as Antioxidants and Free Radical Scavengers

    Article • Journal of Agricultural and Food Chemistry, April 2003, American Chemical Society (ACS)

    Tomas Herraiz

  39. Identification and occurrence of 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid: the main β-carboline alkaloid in smoked foods

    Article • Food Research International, January 2003, Elsevier

    Tomas Herraiz

  40. Identification and occurrence of the bioactive β-carbolines norharman and harman in coffee brews

    Article • Food Additives & Contaminants, August 2002, Taylor & Francis

    Tomas Herraiz

  41. Identification and Occurrence of the Novel Alkaloid Pentahydroxypentyl-tetrahydro-β-carboline-3-carboxylic Acid as a Tryptophan Glycoconjugate in Fruit Juices and Jams

    Article • Journal of Agricultural and Food Chemistry, July 2002, American Chemical Society (ACS)

    Tomas Herraiz

  42. Tetrahydro-β-carboline Alkaloids that Occur in Foods and Biological Systems Act as Radical Scavengers and Antioxidants in the ABTS Assay

    Article • Free Radical Research, January 2002, Taylor & Francis

    Tomas Herraiz

  43. Tetrahydro-β-carbolines, Potential Neuroactive Alkaloids, in Chocolate and Cocoa

    Article • Journal of Agricultural and Food Chemistry, October 2000, American Chemical Society (ACS)

    Tomas Herraiz

  44. Analysis of the bioactive alkaloids tetrahydro-β-carboline and β-carboline in food

    Article • Journal of Chromatography A, June 2000, Elsevier

    Tomas Herraiz

  45. Analysis of tetrahydro-β-carboline-3-carboxylic acids in foods by solid-phase extraction and reversed-phase high-performance liquid chromatography combined with fluorescence detection

    Article • Journal of Chromatography A, February 2000, Elsevier

    Tomas Herraiz

  46. 1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic Acid and 1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid in Fruits

    Article • Journal of Agricultural and Food Chemistry, December 1999, American Chemical Society (ACS)

    Tomas Herraiz

  47. Ethyl 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylate: a novel β-carboline found in alcoholic beverages

    Article • Food Chemistry, August 1999, Elsevier

    Tomas Herraiz

  48. Sample preparation and reversed phase-high performance liquid chromatography analysis of food-derived peptides

    Article • Analytica Chimica Acta, October 1997, Elsevier

    Tomas Herraiz

  49. Presence of tetrahydro-β-carboline-3-carboxylic acids in foods by gas chromatography—mass spectrometry as their N-methoxycarbonyl methyl ester derivatives

    Article • Journal of Chromatography A, March 1997, Elsevier

    Tomas Herraiz

  50. Comparative prediction of the retention behaviour of small peptides in several reversed-phase high-performance liquid chromatography columns by using partial least squares and multiple linear regression

    Article • Analytica Chimica Acta, June 1996, Elsevier

    Tomas Herraiz

  51. Evaluation of solid-phase extraction procedures in peptide analysis

    Article • Journal of Chromatography A, August 1995, Elsevier

    Tomas Herraiz

  52. Reversed-phase HPLC analysis of peptides in standard and dairy samples using on-line absorbance and post-column OPA-fluorescence detection

    Article • European Food Research and Technology, October 1994, Springer Science + Business Media

    Tomas Herraiz

  53. 1,2,3,4-Tetrahydro-.beta.-carboline-3-carboxylic acid and 1-methyl-1,2,3,4-tetrahydro-.beta.-carboline-3-carboxylic acid in wines

    Article • Journal of Agricultural and Food Chemistry, March 1993, American Chemical Society (ACS)

    Tomas Herraiz

  54. Identification and determination of amino acid ethyl esters in wines by capillary gas chromatography-mass spectrometry

    Article • Journal of Agricultural and Food Chemistry, June 1992, American Chemical Society (ACS)

    Tomas Herraiz

  55. Identification of aroma components of Spanish ‘Verdejo’ wine

    Article • Journal of the Science of Food and Agriculture, January 1991, Wiley

    Tomas Herraiz

  56. A contribution to the study of the volatile fraction in distillates of wines made from Muscat grapes (Pisco)

    Article • European Food Research and Technology, June 1990, Springer Science + Business Media

    Tomas Herraiz

  57. Direct Headspace Sampling with On-Column Thermal Focusing in Capillary Gas Chromatography

    Article • Journal of Chromatographic Science, May 1990, Oxford University Press (OUP)

    Tomas Herraiz

  58. Experiments with the PTV in the solvent split mode for concentration of volatiles

    Article • Journal of High Resolution Chromatography, September 1989, Wiley

    Tomas Herraiz

  59. Evaluation of a PTV injector for quantitative analysis of volatile compounds at low concentrations

    Article • Journal of High Resolution Chromatography, June 1989, Wiley

    Tomas Herraiz

  60. Capillary gas chromatographic determination of volatiles in solid matrices by direct introduction using a programmable-temperature vaporizer

    Article • Journal of Chromatography A, January 1989, Elsevier

    Tomas Herraiz

  61. Differences between wines fermented with and without sulphur dioxide using various selected yeasts

    Article • Journal of the Science of Food and Agriculture, January 1989, Wiley

    Tomas Herraiz

  62. Comparison of the performances of hot and cold sample introduction with a programmed-temperature vaporizer in the split and splitless modes

    Article • Journal of Chromatography A, January 1988, Elsevier

    Tomas Herraiz

  63. Gas chromatographic analysis of free carboxylic acids in foods using a micropacked column

    Article • Food Chemistry, January 1988, Elsevier

    Tomas Herraiz

  64. Sampling of volatile components using a PTV in the solvent split mode

    Article • Journal of High Resolution Chromatography, November 1987, Wiley

    Tomas Herraiz

  65. Micropacked columns: a suitable alternative to very thick capillary columns

    Article • Journal of Chromatography A, January 1987, Elsevier

    Tomas Herraiz

  66. Mixed micropacked columns designed for selective separation of fermentation products

    Article • Chromatographia, December 1986, Springer Science + Business Media

    Tomas Herraiz

  67. β-Carboline Alkaloids

    Article • Wiley

    Tomas Herraiz