All Stories

  1. Sex differences in renal acid-base regulation

    Article • AJP Renal Physiology, September 2025, American Physiological Society

    Timo Rieg

  2. Gliflozins in Hypertension: Basic Mechanisms and Clinical Insights

    Article • AJP Renal Physiology, May 2025, American Physiological Society

    Timo Rieg

  3. Lack of renal NHE1 exacerbates lithium‐induced nephrogenic diabetes insipidus

    Article • Acta Physiologica, March 2025, Wiley

    Timo Rieg

  4. Vitamin D3 suppresses Npt2c abundance and differentially modulates phosphate and calcium homeostasis in Npt2a knockout mice

    Article • Scientific Reports, July 2024, Springer Science + Business Media

    Timo Rieg

  5. Genetic deletion of the kidney sodium/proton exchanger-3 (NHE3) does not alter calcium and phosphate balance due to compensatory responses

    Article • Kidney International, July 2024, Elsevier

    Timo Rieg

  6. Intravenous ferric carboxymaltose and ferric derisomaltose alter the intestinal microbiome in female iron-deficient anemic mice

    Article • Bioscience Reports, September 2023, Portland Press Ltd.

    Timo Rieg

  7. Physiopathology of Phosphate Disorders

    Article • Advances in Kidney Disease and Health, March 2023, Elsevier

    Timo Rieg

  8. NHE3 in the thick ascending limb is required for sustained but not acute furosemide-induced urinary acidification

    Article • AJP Renal Physiology, August 2022, American Physiological Society

    Timo Rieg

  9. SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats

    Article • AJP Renal Physiology, June 2022, American Physiological Society

    Timo Rieg, Dr Alexander Staruschenko

  10. Enhanced phosphate absorption in intestinal epithelial cell‐specific NHE3 knockout mice

    Article • Acta Physiologica, January 2022, Wiley

    Timo Rieg

  11. Npt2a as a target for treating hyperphosphatemia

    Article • Biochemical Society Transactions, January 2022, Portland Press Ltd.

    Timo Rieg

  12. Genetic deletion of connexin 37 causes polyuria and polydipsia

    Article • PLOS One, December 2020, PLOS

    Timo Rieg

  13. PF-06869206 is a selective inhibitor of renal Pi transport: evidence from in vitro and in vivo studies

    Article • AJP Renal Physiology, September 2020, American Physiological Society

    Timo Rieg

  14. An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea

    Article • Clinical Science, April 2020, Portland Press Ltd.

    Timo Rieg

  15. Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function

    Article • Journal of the American Society of Nephrology, August 2019, American Society of Nephrology

    Timo Rieg

  16. Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter

    Article • Journal of the American Society of Nephrology, June 2019, American Society of Nephrology

    Timo Rieg

  17. What does sodium‐glucose co‐transporter 1 inhibition add: Prospects for dual inhibition

    Article • Diabetes Obesity and Metabolism, April 2019, Wiley

    Timo Rieg

  18. Contribution of NHE3 and dietary phosphate to lithium pharmacokinetics

    Article • European Journal of Pharmaceutical Sciences, February 2019, Elsevier

    Timo Rieg

  19. Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin–Induced Diarrhea

    Article • The Journal of Infectious Diseases, January 2019, Oxford University Press (OUP)

    Timo Rieg

  20. Development of SGLT1 and SGLT2 inhibitors

    Article • Diabetologia, August 2018, Springer Science + Business Media

    Timo Rieg

  21. Adenylyl cyclase 6 is required for maintaining acid–base homeostasis

    Article • Clinical Science, June 2018, Portland Press Ltd.

    Timo Rieg

  22. Holding tight and staying true: generation of a new tamoxifen-inducible, principal cell-specific mouse

    Article • AJP Renal Physiology, May 2018, American Physiological Society

    Timo Rieg

  23. Body mass-specific Na+-K+-ATPase activity in the medullary thick ascending limb: implications for species-dependent urine concentrating mechanisms

    Article • AJP Regulatory Integrative and Comparative Physiology, April 2018, American Physiological Society

    Timo Rieg

  24. Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis

    Article • Kidney International, August 2017, Elsevier

    Timo Rieg

  25. Reply to “Reduced NHE3 activity results in congenital diarrhea and can predispose to inflammatory bowel disease”

    Article • AJP Regulatory Integrative and Comparative Physiology, March 2017, American Physiological Society

    Timo Rieg

  26. Novel developments in differentiating the role of renal and intestinal sodium hydrogen exchanger 3

    Article • AJP Regulatory Integrative and Comparative Physiology, December 2016, American Physiological Society

    Timo Rieg

  27. Analysis and validation of traits associated with a single nucleotide polymorphism Gly364Ser in catestatin using humanized chromogranin A mouse models

    Article • Journal of Hypertension, January 2016, Wolters Kluwer Health

    Timo Rieg

  28. Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice

    Article • Laboratory Investigation, November 2015, Springer Science + Business Media

    Timo Rieg

  29. Sodium-glucose cotransport

    Article • Current Opinion in Nephrology & Hypertension, September 2015, Wolters Kluwer Health

    Timo Rieg

  30. Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3

    Article • AJP Renal Physiology, June 2015, American Physiological Society

    Timo Rieg

  31. P2Y2receptor activation decreases blood pressure via intermediate conductance potassium channels and connexin 37

    Article • Acta Physiologica, January 2015, Wiley

    Timo Rieg

  32. Renal Phosphate Wasting in the Absence of Adenylyl Cyclase 6

    Article • Journal of the American Society of Nephrology, May 2014, American Society of Nephrology

    Timo Rieg

  33. Regulation of nephron water and electrolyte transport by adenylyl cyclases

    Article • AJP Renal Physiology, April 2014, American Physiological Society

    Timo Rieg

  34. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice

    Article • AJP Renal Physiology, November 2013, American Physiological Society

    Eric Mayoux, Timo Rieg

  35. Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

    Article • AJP Renal Physiology, November 2013, American Physiological Society

    Eric Mayoux, Timo Rieg

  36. Connecting type A intercalated cell metabolic state to V-ATPase function: phosphorylation does matter!

    Article • AJP Renal Physiology, October 2013, American Physiological Society

    Timo Rieg

  37. A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice

    Article • Journal of Visualized Experiments, May 2013, MyJove Corporation

    Timo Rieg

  38. Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus

    Article • AJP Renal Physiology, January 2013, American Physiological Society

    Timo Rieg

  39. Adenylyl Cyclase 6 Enhances NKCC2 Expression and Mediates Vasopressin-Induced Phosphorylation of NKCC2 and NCC

    Article • American Journal Of Pathology, January 2013, Elsevier

    Timo Rieg

  40. Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice

    Article • AJP Renal Physiology, October 2012, American Physiological Society

    Timo Rieg

  41. P2Y receptors and kidney function

    Article • Wiley Interdisciplinary Reviews Membrane Transport and Signalling, August 2012, Wiley

    Timo Rieg

  42. A role for the organic anion transporter OAT3 in renal creatinine secretion in mice

    Article • AJP Renal Physiology, May 2012, American Physiological Society

    Timo Rieg

  43. Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat

    Article • AJP Regulatory Integrative and Comparative Physiology, January 2012, American Physiological Society

    Timo Rieg

  44. Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

    Article • Diabetes, November 2011, American Diabetes Association

    Timo Rieg

  45. Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2receptor system

    Article • AJP Renal Physiology, September 2011, American Physiological Society

    Timo Rieg

  46. P2Y2receptor activation decreases blood pressure and increases renal Na+excretion

    Article • AJP Regulatory Integrative and Comparative Physiology, August 2011, American Physiological Society

    Timo Rieg

  47. Cardiac-Specific Overexpression of Caveolin-3 Attenuates Cardiac Hypertrophy and Increases Natriuretic Peptide Expression and Signaling

    Article • Journal of the American College of Cardiology, May 2011, Elsevier

    Timo Rieg

  48. Functional Maturation of Drug Transporters in the Developing, Neonatal, and Postnatal Kidney

    Article • Molecular Pharmacology, April 2011, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Timo Rieg

  49. Renal protection in chronic kidney disease: hypoxia-inducible factor activation vs. angiotensin II blockade

    Article • AJP Renal Physiology, December 2010, American Physiological Society

    Timo Rieg

  50. Adenylate Cyclase 6 Determines cAMP Formation and Aquaporin-2 Phosphorylation and Trafficking in Inner Medulla

    Article • Journal of the American Society of Nephrology, September 2010, American Society of Nephrology

    Timo Rieg

  51. Purinergic Inhibition of ENaC Produces Aldosterone Escape

    Article • Journal of the American Society of Nephrology, September 2010, American Society of Nephrology

    Timo Rieg

  52. SGLT2 Mediates Glucose Reabsorption in the Early Proximal Tubule

    Article • Journal of the American Society of Nephrology, July 2010, American Society of Nephrology

    Timo Rieg

  53. Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone

    Article • The FASEB Journal, January 2010, Federation of American Societies For Experimental Biology (FASEB)

    Timo Rieg

  54. Unravelling a role for KCNQ1 in K+recycling and gastric acid secretion

    Article • The Journal of Physiology, August 2009, Wiley

    Timo Rieg

  55. β1-Integrin is required for kidney collecting duct morphogenesis and maintenance of renal function

    Article • AJP Renal Physiology, July 2009, American Physiological Society

    Timo Rieg

  56. Adenosine A1 Receptors Determine Glomerular Hyperfiltration and the Salt Paradox in Early Streptozotocin Diabetes Mellitus

    Article • Nephron Physiology, March 2009, Karger Publishers

    Timo Rieg

  57. ATP and adenosine in the local regulation of water transport and homeostasis by the kidney

    Article • AJP Regulatory Integrative and Comparative Physiology, February 2009, American Physiological Society

    Timo Rieg

  58. Thiazolidinedione-Induced Fluid Retention Is Independent of Collecting Duct αENaC Activity

    Article • Journal of the American Society of Nephrology, January 2009, American Society of Nephrology

    Timo Rieg

  59. Paracrine Regulation of the Epithelial Na+Channel in the Mammalian Collecting Duct by Purinergic P2Y2Receptor Tone

    Article • Journal of Biological Chemistry, November 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Timo Rieg

  60. Ornithine decarboxylase inhibitor eliminates hyperresponsiveness of the early diabetic proximal tubule to dietary salt

    Article • AJP Renal Physiology, October 2008, American Physiological Society

    Timo Rieg

  61. Organic Anion Transporter 3 Contributes to the Regulation of Blood Pressure

    Article • Journal of the American Society of Nephrology, May 2008, American Society of Nephrology

    Timo Rieg

  62. Multiple organic anion transporters contribute to net renal excretion of uric acid

    Article • Physiological Genomics, April 2008, American Physiological Society

    Timo Rieg

  63. Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics

    Article • AJP Renal Physiology, April 2008, American Physiological Society

    Timo Rieg

  64. Vasopressin regulation of inner medullary collecting ducts and compensatory changes in mice lacking adenosine A1receptors

    Article • AJP Renal Physiology, March 2008, American Physiological Society

    Timo Rieg

  65. Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption

    Article • The FASEB Journal, November 2007, Federation of American Societies For Experimental Biology (FASEB)

    Timo Rieg

  66. The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion

    Article • Kidney International, September 2007, Elsevier

    Timo Rieg

  67. Aldosterone-induced Sgk1 relieves Dot1a-Af9–mediated transcriptional repression of epithelial Na+ channel α

    Article • Journal of Clinical Investigation, March 2007, American Society for Clinical Investigation

    Timo Rieg

  68. Adenosine A1 receptors determine effects of caffeine on total fluid intake but not caffeine appetite

    Article • European Journal of Pharmacology, January 2007, Elsevier

    Timo Rieg

  69. Combined Effects of Carbonic Anhydrase Inhibitor and Adenosine A1 Receptor Antagonist on Hemodynamic and Tubular Function in the Kidney

    Article • Kidney and Blood Pressure Research, January 2007, Karger Publishers

    Timo Rieg

  70. Stimulation of serum- and glucocorticoid-regulated kinase-1 gene expression by endothelin-1

    Article • Biochemical Pharmacology, April 2006, Elsevier

    Timo Rieg

  71. Decreased Renal Organic Anion Secretion and Plasma Accumulation of Endogenous Organic Anions inOAT1Knock-out Mice

    Article • Journal of Biological Chemistry, December 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Timo Rieg

  72. Requirement of Intact Adenosine A1 Receptors for the Diuretic and Natriuretic Action of the Methylxanthines Theophylline and Caffeine

    Article • Journal of Pharmacology and Experimental Therapeutics, December 2004, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Timo Rieg

  73. Kidney function in mice: thiobutabarbital versus ?-chloralose anesthesia

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, September 2004, Springer Science + Business Media

    Timo Rieg

  74. Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice

    Article • Pflügers Archiv - European Journal of Physiology, May 2004, Springer Science + Business Media

    Timo Rieg

  75. Different actions of protein kinase C isoforms α and ε on gastric acid secretion

    Article • British Journal of Pharmacology, July 2002, Wiley

    Timo Rieg