All Stories

  1. Maresin 1 modulates renal and cardiac lipid profiles in hypertensive rats
  2. The effects of Cannabidiol on podocytes in vitro
  3. Serine proteases and protease-activated receptors signaling in the kidney
  4. Effect of Renal Denervation on Early and Late Stages of Diabetic Nephropathy
  5. Discovering physiology: a high school student’s journey into STEM: perspective and advice
  6. Gliflozins in Hypertension: Basic Mechanisms and Clinical Insights
  7. Potassium supplementation and depletion during development of salt-sensitive hypertension in male and female SS rats
  8. Targeting REDD1 in Podocytes: A Promising Strategy for Mitigating Diabetic Kidney Injury
  9. Electrolyte and metabolite composition of cystic fluid from a rat model of ARPKD
  10. Endoplasmic reticulum-associated degradation: a novel therapeutic avenue for ADPKD
  11. Mechanistic Insights Into Redox Damage of the Podocyte in Hypertension
  12. Role of Kir5.1 (Kcnj16) Channels in Regulating Renal Ammonia Metabolism during Metabolic Acidosis in Dahl Salt-Sensitive Rats
  13. Role of cGAS/STING pathway in aging and sexual dimorphism in diabetic kidney disease
  14. The effects of cannabinoids on the kidney
  15. Characterization of a novel variant in KCNJ16 , encoding K ir 5.1 channel
  16. Effects of zinc in podocytes and cortical collecting duct in vitro and Dahl salt-sensitive rats in vivo
  17. Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity
  18. Renin-angiotensin system-mediated nitric oxide signaling in podocytes
  19. Vitamin D3 suppresses Npt2c abundance and differentially modulates phosphate and calcium homeostasis in Npt2a knockout mice
  20. SGLT2 inhibitors: not every drug has the same effect
  21. Calcium signalling and transport in the kidney
  22. Opioids and the Kidney: A Compendium
  23. Effect of SGLT2 inhibition on salt-induced hypertension in female Dahl SS rats
  24. Repeated seizures lead to progressive ventilatory dysfunction in SSKcnj16−/− rats
  25. Kir7.1 knockdown and inhibition alter renal electrolyte handling but not the development of hypertension in Dahl salt-sensitive rats
  26. Call for Papers: podocyte physiology and pathophysiology
  27. The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats
  28. Ion channels and channelopathies in glomeruli
  29. Modulation of P2X 4 receptor activity by ivermectin and 5‐BDBD has no effect on the development of ARPKD ...
  30. Kir5.1 channels: potential role in epilepsy and seizure disorders
  31. Modulation of blood pressure regulatory genes in the Agtrap‐Plod1 locus associated with a deletion in Clcn6
  32. SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats
  33. Astrocytic responses to high glucose impair barrier formation in cerebral microvessel endothelial cells
  34. Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation
  35. Crosstalk between epithelial sodium channels (ENaC) and basolateral potassium channels (Kir4.1/Kir5.1) in the cortical collecting duct
  36. Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys
  37. Cytoskeleton Rearrangements Modulate TRPC6 Channel Activity in Podocytes
  38. Scanning ion conductance microscopy of live human glomerulus
  39. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores
  40. Kcnj16 knockout produces audiogenic seizures in the Dahl salt-sensitive rat
  41. American Journal of Physiology-Renal Physiology Collections: Hypertension
  42. Behavioral, metabolic, and renal outcomes of 1-month isolation in adolescent male Dahl salt-sensitive rats
  43. O’Brien Kidney Research Centers
  44. SGLT2 inhibitors: diabetic kidney disease and beyond
  45. Role of opioid signaling in kidney damage during the development of salt-induced hypertension
  46. NOX4‐dependent regulation of ENaC in hypertension and diabetic kidney disease
  47. Effects of uric acid dysregulation on the kidney
  48. Expression, localization, and functional properties of inwardly rectifying K+channels in the kidney
  49. Metabolic rewiring of the hypertensive kidney
  50. Postprandial effects on electrolyte homeostasis in the kidney
  51. Relationship between the renin–angiotensin–aldosterone system and renal Kir5.1 channels
  52. Vibrodissociation method for isolation of defined nephron segments from human and rodent kidneys
  53. Increased ENaC activity during kidney preservation in Wisconsin solution
  54. The importance of the pH-sensitive Kir5.1 channel in short-term and long-term regulation of pH
  55. Postprandial Effects on ENaC-Mediated Sodium Absorption
  56. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)
  57. Visualization and Quantification of Mitochondrial Structure in the Endothelium of Intact Arteries
  58. Characterization of purinergic receptor expression in ARPKD cystic epithelia
  59. Endothelin receptor A and p66Shc regulate spontaneous Ca2+oscillations in smooth muscle cells controlling renal arterial spontaneous motion
  60. Protective role of Trpc6 knockout in the progression of diabetic kidney disease
  61. Distal tubule basolateral potassium channels
  62. Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats
  63. A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD
  64. Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections
  65. β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
  66. Beneficial Effects of High Potassium
  67. A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease
  68. Role of adaptor protein p66Shc in renal pathologies
  69. Nitric oxide production by glomerular podocytes
  70. Essential role of Kir5.1 channels in renal salt handling and blood pressure control
  71. Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure
  72. Intravital imaging of the kidney in a rat model of salt-sensitive hypertension
  73. Involvement of ENaC in the development of salt-sensitive hypertension
  74. The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses
  75. Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats
  76. Hypertension and Diabetes Mellitus
  77. The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling
  78. Functional and therapeutic importance of purinergic signaling in polycystic kidney disease
  79. Protease-activated receptors in kidney disease progression
  80. The function of SH2B3 (LNK) in the kidney
  81. High salt diet and caffeine: food for thought
  82. Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats
  83. Regulation of Polycystin-1 Function by Calmodulin Binding
  84. Two-photon imaging of endothelin-1-mediated intracellular Ca 2+ handling in smooth muscle cells of rat renal resistance arteries
  85. Renal channels and transporters in Renin KO rats
  86. p66Shc regulates renal vascular tone in hypertension-induced nephropathy
  87. Role and mechanisms of regulation of the basolateral Kir4.1/Kir5.1K+channels in the distal tubules
  88. Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes
  89. Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage
  90. Fundamentals of Epithelial Na+ Absorption
  91. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats
  92. Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels
  93. Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney
  94. TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases
  95. Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
  96. Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
  97. Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
  98. Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption
  99. Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation
  100. Inhibition of ENaC by Endothelin-1
  101. Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats
  102. Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition
  103. To cleave or not to cleave: role of ADAM17 in cell proliferation in PKD
  104. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
  105. Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption
  106. Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat
  107. PC and PKC: in vivo vs. in vitro
  108. Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli
  109. Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine
  110. Aldosterone-dependent trans-activation and epigenetic derepression of ENaC: where is the balance?
  111. Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells
  112. Orally Active Epoxyeicosatrienoic Acid Analog Attenuates Kidney Injury in Hypertensive Dahl Salt-Sensitive Rat
  113. Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney
  114. Epidermal growth factors in the kidney and relationship to hypertension
  115. Real-time electrochemical detection of ATP and H2O2 release in freshly isolated kidneys
  116. Deficiency of Renal Cortical EGF Increases ENaC Activity and Contributes to Salt-Sensitive Hypertension
  117. Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct
  118. ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1
  119. Recording Ion Channels in Isolated, Split-Opened Tubules
  120. Single-Channel Analysis of TRPC Channels in the Podocytes of Freshly Isolated Glomeruli
  121. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease
  122. Direct Activation of ENaC by Angiotensin II: Recent Advances and New Insights
  123. Regulation of TRPC6 channels by non-steroidal anti-inflammatory drugs
  124. Ion transport in the connecting tubule and cortical collecting duct
  125. Mechanisms of epithelial sodium channel (ENaC) regulation by cortactin: Involvement of dynamin
  126. Role of βPix in the Kidney
  127. Angiotensin II Increases Activity of the Epithelial Na+Channel (ENaC) in Distal Nephron Additively to Aldosterone
  128. Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells
  129. Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)
  130. Cortical actin binding protein cortactin mediates ENaC activity via Arp2/3 complex
  131. NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli
  132. Novel Role of Rac1/WAVE Signaling Mechanism in Regulation of the Epithelial Na+ Channel
  133. Endothelin-1 Inhibits the Epithelial Na+ Channel through  Pix/14-3-3/Nedd4-2
  134. Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel
  135. Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na+ Channel
  136. Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors
  137. The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC
  138. Muscarinic M1 modulation of acid-sensing ion channels
  139. Peroxisome Proliferator-Activated Receptor γ Antagonists Decrease Na+ Transport via the Epithelial Na+ Channel
  140. Regulation of the epithelial sodium channels (ENaC) by small G proteins and phosphatidylinositides
  141. Intrinsic Voltage Dependence of the Epithelial Na+Channel Is Masked by a Conserved Transmembrane Domain Tryptophan
  142. EGF and its related growth factors mediate sodium transport in mpkCCDc14cells via ErbB2 (neu/HER-2) receptor
  143. Regulation of ENaC expression at the cell surface by Rab11
  144. Insight toward epithelial Na+channel mechanism revealed by the acid-sensing ion channel 1 structure
  145. Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons
  146. Ion Channel Regulation by Ras, Rho, and Rab Small GTPases
  147. Molecular Determinants of PI(4,5)P2and PI(3,4,5)P3Regulation of the Epithelial Na+Channel
  148. Acute Regulation of the Epithelial Na+ Channel by Phosphatidylinositide 3-OH Kinase Signaling in Native Collecting Duct Principal Cells
  149. Binding and direct activation of the epithelial Na+channel (ENaC) by phosphatidylinositides
  150. Quantifying RhoA Facilitated Trafficking of the Epithelial Na+Channel toward the Plasma Membrane with Total Internal Reflection Fluorescence-Fluorescence Recovery after Photobleaching
  151. Magnesium permeation through mechanosensitive channels: single-current measurements
  152. Rapid Translocation and Insertion of the Epithelial Na+Channel in Response to RhoA Signaling
  153. Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides
  154. Subunit-dependent cadmium and nickel inhibition of acid-sensing ion channels
  155. Regulation of Epithelial Na+Channel Activity by Conserved Serine/Threonine Switches within Sorting Signals
  156. Identification of a Functional Phosphatidylinositol 3,4,5-Trisphosphate Binding Site in the Epithelial Na+Channel
  157. ENaC stoichiometry
  158. Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells
  159. Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel
  160. Rho Small GTPases Activate the Epithelial Na+Channel
  161. Ras Activates the Epithelial Na+Channel through Phosphoinositide 3-OH Kinase Signaling
  162. Fluorescence Resonance Energy Transfer Analysis of Subunit Stoichiometry of the Epithelial Na+Channel
  163. Mechanosensitive cation channels in human leukaemia cells: calcium permeation and blocking effect
  164. Giant multimodal heart motoneurons of Achatina fulica: a new cardioregulatory input in pulmonates