All Stories

  1. Targeting REDD1 in Podocytes: A Promising Strategy for Mitigating Diabetic Kidney Injury
  2. Opioids and the Kidney: A Compendium
  3. Repeated seizures lead to progressive ventilatory dysfunction in SSKcnj16−/− rats
  4. Kir7.1 knockdown and inhibition alter renal electrolyte handling but not the development of hypertension in Dahl salt-sensitive rats
  5. Call for Papers: podocyte physiology and pathophysiology
  6. The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats
  7. Ion channels and channelopathies in glomeruli
  8. Modulation of P2X 4 receptor activity by ivermectin and 5‐BDBD has no effect on the development of ARPKD ...
  9. Kir5.1 channels: potential role in epilepsy and seizure disorders
  10. Modulation of blood pressure regulatory genes in the Agtrap‐Plod1 locus associated with a deletion in Clcn6
  11. SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats
  12. Astrocytic responses to high glucose impair barrier formation in cerebral microvessel endothelial cells
  13. Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation
  14. Crosstalk between epithelial sodium channels (ENaC) and basolateral potassium channels (Kir4.1/Kir5.1) in the cortical collecting duct
  15. Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys
  16. Cytoskeleton Rearrangements Modulate TRPC6 Channel Activity in Podocytes
  17. Scanning ion conductance microscopy of live human glomerulus
  18. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores
  19. Kcnj16 knockout produces audiogenic seizures in the Dahl salt-sensitive rat
  20. American Journal of Physiology-Renal Physiology Collections: Hypertension
  21. Behavioral, metabolic, and renal outcomes of 1-month isolation in adolescent male Dahl salt-sensitive rats
  22. O’Brien Kidney Research Centers
  23. SGLT2 inhibitors: diabetic kidney disease and beyond
  24. Role of opioid signaling in kidney damage during the development of salt-induced hypertension
  25. NOX4‐dependent regulation of ENaC in hypertension and diabetic kidney disease
  26. Effects of uric acid dysregulation on the kidney
  27. Expression, localization, and functional properties of inwardly rectifying K+channels in the kidney
  28. Metabolic rewiring of the hypertensive kidney
  29. Postprandial effects on electrolyte homeostasis in the kidney
  30. Relationship between the renin–angiotensin–aldosterone system and renal Kir5.1 channels
  31. Vibrodissociation method for isolation of defined nephron segments from human and rodent kidneys
  32. Increased ENaC activity during kidney preservation in Wisconsin solution
  33. The importance of the pH-sensitive Kir5.1 channel in short-term and long-term regulation of pH
  34. Postprandial Effects on ENaC-Mediated Sodium Absorption
  35. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)
  36. Visualization and Quantification of Mitochondrial Structure in the Endothelium of Intact Arteries
  37. Characterization of purinergic receptor expression in ARPKD cystic epithelia
  38. Endothelin receptor A and p66Shc regulate spontaneous Ca2+oscillations in smooth muscle cells controlling renal arterial spontaneous motion
  39. Protective role of Trpc6 knockout in the progression of diabetic kidney disease
  40. Distal tubule basolateral potassium channels
  41. Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats
  42. A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD
  43. Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections
  44. β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
  45. Beneficial Effects of High Potassium
  46. A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease
  47. Role of adaptor protein p66Shc in renal pathologies
  48. Nitric oxide production by glomerular podocytes
  49. Essential role of Kir5.1 channels in renal salt handling and blood pressure control
  50. Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure
  51. Intravital imaging of the kidney in a rat model of salt-sensitive hypertension
  52. Involvement of ENaC in the development of salt-sensitive hypertension
  53. The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses
  54. Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats
  55. Hypertension and Diabetes Mellitus
  56. The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling
  57. Functional and therapeutic importance of purinergic signaling in polycystic kidney disease
  58. Protease-activated receptors in kidney disease progression
  59. The function of SH2B3 (LNK) in the kidney
  60. High salt diet and caffeine: food for thought
  61. Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats
  62. Regulation of Polycystin-1 Function by Calmodulin Binding
  63. Two-photon imaging of endothelin-1-mediated intracellular Ca 2+ handling in smooth muscle cells of rat renal resistance arteries
  64. Renal channels and transporters in Renin KO rats
  65. p66Shc regulates renal vascular tone in hypertension-induced nephropathy
  66. Role and mechanisms of regulation of the basolateral Kir4.1/Kir5.1K+channels in the distal tubules
  67. Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes
  68. Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage
  69. Fundamentals of Epithelial Na+ Absorption
  70. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats
  71. Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels
  72. Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney
  73. TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases
  74. Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
  75. Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
  76. Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
  77. Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption
  78. Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation
  79. Inhibition of ENaC by Endothelin-1
  80. Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats
  81. Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition
  82. To cleave or not to cleave: role of ADAM17 in cell proliferation in PKD
  83. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
  84. Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption
  85. Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat
  86. PC and PKC: in vivo vs. in vitro
  87. Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli
  88. Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine
  89. Aldosterone-dependent trans-activation and epigenetic derepression of ENaC: where is the balance?
  90. Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells
  91. Orally Active Epoxyeicosatrienoic Acid Analog Attenuates Kidney Injury in Hypertensive Dahl Salt-Sensitive Rat
  92. Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney
  93. Epidermal growth factors in the kidney and relationship to hypertension
  94. Real-time electrochemical detection of ATP and H2O2 release in freshly isolated kidneys
  95. Deficiency of Renal Cortical EGF Increases ENaC Activity and Contributes to Salt-Sensitive Hypertension
  96. Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct
  97. ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1
  98. Recording Ion Channels in Isolated, Split-Opened Tubules
  99. Single-Channel Analysis of TRPC Channels in the Podocytes of Freshly Isolated Glomeruli
  100. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease
  101. Direct Activation of ENaC by Angiotensin II: Recent Advances and New Insights
  102. Regulation of TRPC6 channels by non-steroidal anti-inflammatory drugs
  103. Ion transport in the connecting tubule and cortical collecting duct
  104. Mechanisms of epithelial sodium channel (ENaC) regulation by cortactin: Involvement of dynamin
  105. Role of βPix in the Kidney
  106. Angiotensin II Increases Activity of the Epithelial Na+Channel (ENaC) in Distal Nephron Additively to Aldosterone
  107. Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells
  108. Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)
  109. Cortical actin binding protein cortactin mediates ENaC activity via Arp2/3 complex
  110. NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli
  111. Novel Role of Rac1/WAVE Signaling Mechanism in Regulation of the Epithelial Na+ Channel
  112. Endothelin-1 Inhibits the Epithelial Na+ Channel through  Pix/14-3-3/Nedd4-2
  113. Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel
  114. Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na+ Channel
  115. Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors
  116. The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC
  117. Muscarinic M1 modulation of acid-sensing ion channels
  118. Peroxisome Proliferator-Activated Receptor γ Antagonists Decrease Na+ Transport via the Epithelial Na+ Channel
  119. Regulation of the epithelial sodium channels (ENaC) by small G proteins and phosphatidylinositides
  120. Intrinsic Voltage Dependence of the Epithelial Na+Channel Is Masked by a Conserved Transmembrane Domain Tryptophan
  121. EGF and its related growth factors mediate sodium transport in mpkCCDc14cells via ErbB2 (neu/HER-2) receptor
  122. Regulation of ENaC expression at the cell surface by Rab11
  123. Insight toward epithelial Na+channel mechanism revealed by the acid-sensing ion channel 1 structure
  124. Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons
  125. Ion Channel Regulation by Ras, Rho, and Rab Small GTPases
  126. Molecular Determinants of PI(4,5)P2and PI(3,4,5)P3Regulation of the Epithelial Na+Channel
  127. Acute Regulation of the Epithelial Na+ Channel by Phosphatidylinositide 3-OH Kinase Signaling in Native Collecting Duct Principal Cells
  128. Binding and direct activation of the epithelial Na+channel (ENaC) by phosphatidylinositides
  129. Quantifying RhoA Facilitated Trafficking of the Epithelial Na+Channel toward the Plasma Membrane with Total Internal Reflection Fluorescence-Fluorescence Recovery after Photobleaching
  130. Magnesium permeation through mechanosensitive channels: single-current measurements
  131. Rapid Translocation and Insertion of the Epithelial Na+Channel in Response to RhoA Signaling
  132. Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides
  133. Subunit-dependent cadmium and nickel inhibition of acid-sensing ion channels
  134. Regulation of Epithelial Na+Channel Activity by Conserved Serine/Threonine Switches within Sorting Signals
  135. Identification of a Functional Phosphatidylinositol 3,4,5-Trisphosphate Binding Site in the Epithelial Na+Channel
  136. ENaC stoichiometry
  137. Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells
  138. Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel
  139. Rho Small GTPases Activate the Epithelial Na+Channel
  140. Ras Activates the Epithelial Na+Channel through Phosphoinositide 3-OH Kinase Signaling
  141. Fluorescence Resonance Energy Transfer Analysis of Subunit Stoichiometry of the Epithelial Na+Channel
  142. Mechanosensitive cation channels in human leukaemia cells: calcium permeation and blocking effect
  143. Giant multimodal heart motoneurons of Achatina fulica: a new cardioregulatory input in pulmonates