All Stories

  1. Magnetic Resonance Imaging-negative Encephalomyeloradiculopathy Diagnosed by Anti-lactosylceramide Antibody Positivity and Electrophysiological Findings: A Case Report and Review of the Literature

    Article • Internal Medicine, March 2026, Japanese Society of Internal Medicine

    Professor Tatsuro Mutoh

  2. Pediatric Encephalomyeloradiculoneuropathy With High Lactate in Cerebrospinal Fluid and Magnetic Resonance Spectroscopy: A Case Report

    Article • Journal of Child Neurology, December 2025, SAGE Publications

    Professor Tatsuro Mutoh

  3. Elevated TFEB expression with limited activation in peripheral blood mononuclear cells reflects altered lysosomal enzyme dynamics in Parkinson's disease

    Article • Neurobiology of Disease, December 2025, Elsevier

    Professor Tatsuro Mutoh

  4. Cerebrospinal fluid sphingolipid and sterol metabolite profiles of neurologically normal subjects

    Article • Molecular and Cellular Biochemistry, July 2025, Springer Science + Business Media

    Professor Tatsuro Mutoh

  5. Effective relapse prevention with monthly intravenous immunoglobulin therapy in a pediatric patient with anti-neutral glycolipid antibody-positive Encephalomyeloradiculoneuropathy

    Article • Brain and Development Case Reports, June 2025, Elsevier

    Professor Tatsuro Mutoh

  6. Activation of α7 nicotinic acetylcholine receptor augments nerve growth factor action on PCtrk cells

    Article • Toxicology, December 2024, Elsevier

    Professor Tatsuro Mutoh

  7. Increase in Adult Patients with Varicella Zoster Virus–Related Central Nervous System Infections, Japan

    Article • Emerging Infectious Diseases, December 2024, Centers for Disease Control and Prevention (CDC)

    Professor Tatsuro Mutoh

  8. Uric acid and alterations of purine recycling disorders in Parkinson’s disease: a cross-sectional study

    Article • npj Parkinson s Disease, September 2024, Springer Science + Business Media

    Professor Tatsuro Mutoh

  9. Enzymatic properties and clinical associations of serum alpha‐galactosidase A in Parkinson's disease

    Article • Annals of Clinical and Translational Neurology, July 2023, Wiley

    Professor Tatsuro Mutoh

  10. Sphingolipid abnormalities in encephalomyeloradiculoneuropathy (EMRN) are associated with an anti‐neutral glycolipid antibody

    Article • FEBS Open Bio, March 2023, Wiley

    Professor Tatsuro Mutoh

  11. A pilot study assessing sphingolipids and glycolipids dysmetabolism in idiopathic normal pressure hydrocephalus

    Article • Biochemical and Biophysical Research Communications, January 2023, Elsevier

    Professor Tatsuro Mutoh

  12. Ceramides accumulation and complement activation in patients with EMRN

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, March 2022, Elsevier

    Professor Tatsuro Mutoh

  13. Piroheptine for Treating Parkinson

    Article • January 2022, Springer Science + Business Media

    Professor Tatsuro Mutoh

  14. Mazaticol for Treating Parkinson

    Article • January 2022, Springer Science + Business Media

    Professor Tatsuro Mutoh

  15. Acknowledgments

    Article • January 2022, Elsevier

    Professor Tatsuro Mutoh

  16. Detection of human herpesviruses in cerebrospinal fluids collected from patients suspected of neuroinfectious diseases

    Article • Journal of NeuroVirology, December 2021, Springer Science + Business Media

    Professor Tatsuro Mutoh

  17. Detection of circulating tumor DNA in cerebrospinal fluid prior to diagnosis of spinal cord lymphoma by flow cytometric and cytologic analyses

    Article • Annals of Hematology, October 2021, Springer Science + Business Media

    Professor Tatsuro Mutoh

  18. Corrigendum to “Galabiosylceramide is present in human cerebrospinal fluid”

    Article • Biochemical and Biophysical Research Communications, March 2021, Elsevier

    Professor Tatsuro Mutoh

  19. Cerebrospinal Fluid Profiles in Parkinson’s Disease: No Accumulation of Glucosylceramide, but Significant Downregulation of Active Complement C5 Fragment

    Article • Journal of Parkinson’s Disease, February 2021, IOS Press

    Professor Tatsuro Mutoh

  20. Review article for the close relationship between neuroinflammation and glycosphingolipids

    Article • Trends in Glycoscience and Glycotechnology, January 2021, Forum: Carbohydrates Coming of Age

    Professor Tatsuro Mutoh

  21. Galabiosylceramide is present in human cerebrospinal fluid

    Article • Biochemical and Biophysical Research Communications, January 2021, Elsevier

    Professor Tatsuro Mutoh

  22. Clioquinol kills astrocyte-derived KT-5 cells by the impairment of the autophagy–lysosome pathway

    Article • Archives of Toxicology, November 2020, Springer Science + Business Media

    Professor Tatsuro Mutoh

  23. Serum IgG anti-GD1a antibody and mEGOS predict outcome in Guillain-Barré syndrome

    Article • Journal of Neurology Neurosurgery & Psychiatry, October 2020, BMJ

    Professor Tatsuro Mutoh

  24. cross-talk between Trk neurotrphin receptor and innate immunity

    Article • International Journal of Molecular Sciences, September 2020, MDPI AG

    Professor Tatsuro Mutoh

  25. Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease

    Article • Brain, March 2020, Oxford University Press (OUP)

    Professor Tatsuro Mutoh

  26. Mazaticol for Treating Parkinson

    Article • January 2020, Springer Science + Business Media

    Professor Tatsuro Mutoh

  27. Better neuroradiological approach for the diagnosis of early-stage Parkinson's disease patients

    Article • January 2020, Elsevier

    Professor Tatsuro Mutoh

  28. Piroheptine for Treating Parkinson

    Article • December 2019, Springer Science + Business Media

    Professor Tatsuro Mutoh

  29. Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker?

    Article • Parkinsonism & Related Disorders, April 2019, Elsevier

    Professor Tatsuro Mutoh

  30. A Patient With Thiamine Deficiency Exhibiting Muscle Edema Suggested by MRI

    Article • Frontiers in Neurology, December 2018, Frontiers

    Professor Tatsuro Mutoh

  31. Changes in Serial D-Dimer Levels Predict the Prognoses of Trousseau's Syndrome Patients

    Article • Frontiers in Neurology, July 2018, Frontiers

    Professor Tatsuro Mutoh

  32. Anti-GM1 ganglioside antibodies modulate membrane-associated sphingomyelin metabolism by altering neutral sphingomyelinase activity

    Article • Molecular and Cellular Neuroscience, June 2018, Elsevier

    Professor Tatsuro Mutoh

  33. Markers for Guillain-Barré syndrome with poor prognosis: a multi-center study

    Article • Journal of the Peripheral Nervous System, September 2017, Wiley

    Professor Tatsuro Mutoh, Kyoichi Nomura, Yuko Yamagishi

  34. Usefulness of combining 123 I-FP-CIT-SPECT striatal asymmetry index and cardiac 123 I-metaiodobenzylguanidine scintigraphy examinations for diagnosis of parkinsonisms

    Article • Journal of the Neurological Sciences, June 2017, Elsevier

    Professor Tatsuro Mutoh

  35. MR neurography for the evaluation of CIDP

    Article • Muscle & Nerve, December 2016, Wiley

    Professor Tatsuro Mutoh

  36. Differentiation of cancer from atrial fibrillation in patients with acute multifocal stroke

    Article • Journal of the Neurological Sciences, September 2016, Elsevier

    Professor Tatsuro Mutoh

  37. encephalomyeloradiculoneuropathy patient showing anti-neutral glycolipids antibodies and epilepsy

    Article • Neurology and Clinical Neuroscience, March 2016, Wiley

    Professor Tatsuro Mutoh

  38. brain abscess

    Article • Neurology and Clinical Neuroscience, December 2015, Wiley

    Professor Tatsuro Mutoh

  39. Retrospective analysis of parkinsonian patients exhibiting normal 123I-MIBG cardiac uptake

    Article • Journal of the Neurological Sciences, December 2015, Elsevier

    Professor Tatsuro Mutoh

  40. Voriconazole-responsive Disseminated Nodular Lesions on Spinal MRI

    Article • Internal Medicine, January 2015, Japanese Society of Internal Medicine

    Professor Tatsuro Mutoh

  41. Neurotropin promotes NGF signaling through interaction of GM1 ganglioside with Trk neurotrophin receptor in PC12 cells

    Article • Brain Research, January 2015, Elsevier

    Professor Tatsuro Mutoh

  42. Hypertrophic pachymeningitis and encephalitis in a patient with relapsing polychondritis

    Article • Neurology and Clinical Neuroscience, November 2014, Wiley

    Professor Tatsuro Mutoh

  43. An update on diagnostic imaging studies for viral encephalitis

    Article • Future Virology, September 2012, Future Medicine

    Professor Tatsuro Mutoh

  44. Winged scapula in patients with myotonic dystrophy type 1

    Article • Neuromuscular Disorders, August 2012, Elsevier

    Professor Tatsuro Mutoh

  45. Extracorporeal Aβ removal system (EARS) for Alzheimer's disease therapy: Novel devices with fragments of hollow fibers removed Aβ effectively both in vitro and in vivo

    Article • Alzheimer s & Dementia, July 2012, Elsevier

    Professor Tatsuro Mutoh

  46. Glycobiology and neurological disorders

    Article • Rinsho Shinkeigaku, January 2011, Societas Neurologica Japonica

    Professor Tatsuro Mutoh

  47. Transient Splenial Lesion of the Corpus Callosum in H1N1 Influenza Virus-Associated Encephalitis/Encephalopathy

    Article • Internal Medicine, January 2011, Japanese Society of Internal Medicine

    Professor Tatsuro Mutoh

  48. Neurotrophin Levels in Cerebrospinal Fluid of Adult Patients with Meningitis and Encephalitis

    Article • European Neurology, January 2011, Karger Publishers

    Professor Tatsuro Mutoh

  49. Stimulated neuronal expression of brain-derived neurotrophic factor by Neurotropin

    Article • Molecular and Cellular Neuroscience, November 2010, Elsevier

    Professor Tatsuro Mutoh

  50. Novel therapeutic approach for Alzheimer’s disease by removing amyloid β protein from the brain with an extracorporeal removal system

    Article • Journal of Artificial Organs, February 2010, Springer Science + Business Media

    Professor Tatsuro Mutoh

  51. Muscle MRI in Myotonic Dystrophy Type 1 with Foot Drop

    Article • European Neurology, January 2010, Karger Publishers

    Professor Tatsuro Mutoh

  52. Clioquinol inhibits NGF-induced Trk autophosphorylation and neurite outgrowth in PC12 cells

    Article • Brain Research, November 2009, Elsevier

    Professor Tatsuro Mutoh

  53. Toward the novel method of treatment for Alzheimer's disease: Extra-corporeal Aβ removal system (EARS)

    Article • Alzheimer s & Dementia, July 2009, Elsevier

    Professor Tatsuro Mutoh

  54. Electroretinograms in three cases of Creutzfeldt-Jakob disease with visual disturbances

    Article • Japanese Journal of Ophthalmology, January 2009, Springer Science + Business Media

    Professor Tatsuro Mutoh

  55. Acute Autonomic, Sensory and Motor Neuropathy: Successful Treatment with IVIg

    Article • Internal Medicine, January 2009, Japanese Society of Internal Medicine

    Professor Tatsuro Mutoh

  56. β-amyloid (25–35) enhances lipid metabolism and protein ubiquitination in cultured neurons

    Article • Journal of Neuroscience Research, January 2007, Wiley

    Professor Tatsuro Mutoh

  57. Role of Glycosphingolipids and Therapeutic Perspectives on Alzheimers Disease

    Article • CNS & Neurological Disorders - Drug Targets, August 2006, Bentham Science Publishers

    Professor Tatsuro Mutoh

  58. Postinfectious Myeloradiculoneuropathy With Cranial Nerve Involvements Associated With Human Herpesvirus 7 Infection

    Article • Archives of Neurology, November 2005, American Medical Association (AMA)

    Professor Tatsuro Mutoh

  59. Impairment of Trk-Neurotrophin Receptor by the Serum of a Patient With Subacute Sensory Neuropathy

    Article • Archives of Neurology, October 2005, American Medical Association (AMA)

    Professor Tatsuro Mutoh

  60. Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein

    Article • Molecular Brain Research, June 2005, Elsevier

    Professor Tatsuro Mutoh

  61. Tyrosine phosphorylation of the catalytic subunit p110 of phosphatidylinositol-3 kinase induced by HMG-CoA reductase inhibitor inhibits its kinase activity in L6 myoblasts

    Article • FEBS Letters, October 2001, Wiley

    Professor Tatsuro Mutoh

  62. Biological Implication of the Membrane Rafts in Neuronal Cells

    Article • Trends in Glycoscience and Glycotechnology, January 2001, Forum: Carbohydrates Coming of Age

    Professor Tatsuro Mutoh

  63. Spinal Cavitous Hemorrhagic Infarction with Abdominal Aortic Aneurysm

    Article • European Neurology, January 2001, Karger Publishers

    Professor Tatsuro Mutoh

  64. HMG-CoA reductase inhibitor induces a transient activation of high affinity nerve growth factor receptor, Trk, and morphological differentiation with fatal outcome in PC12 cells

    Article • Brain Research, March 2000, Elsevier

    Professor Tatsuro Mutoh

  65. Posterior Thoracic Spinal Cord Infarction: Complication of Thoracoabdominal Aortic Aneurysm

    Article • European Neurology, January 2000, Karger Publishers

    Professor Tatsuro Mutoh

  66. MRI findings of benign monomelic amyotrophy of lower limb

    Article • Journal of the Neurological Sciences, June 1999, Elsevier

    Professor Tatsuro Mutoh

  67. Role of tyrosine phosphorylation of phospholipase C γ1 in the signaling pathway of HMG-CoA reductase inhibitor-induced cell death of L6 myoblasts

    Article • FEBS Letters, March 1999, Wiley

    Professor Tatsuro Mutoh

  68. Involvement of tyrosine phosphorylation in HMG-CoA reductase inhibitor-induced cell death in L6 myoblasts

    Article • FEBS Letters, February 1999, Wiley

    Professor Tatsuro Mutoh

  69. Expression of GDNF receptor (RET and GDNFR-α) mRNAs in the spinal cord of patients with amyotrophic lateral sclerosis

    Article • Brain Research, February 1999, Elsevier

    Professor Tatsuro Mutoh

  70. Influence of endogenous GM1 ganglioside on TrkB activity, in cultured neurons

    Article • FEBS Letters, November 1998, Wiley

    Professor Tatsuro Mutoh

  71. HMG-CoA reductase inhibitor-induced L6 myoblast cell death: involvement of the phosphatidylinositol 3-kinase pathway

    Article • FEBS Letters, November 1998, Wiley

    Professor Tatsuro Mutoh

  72. Differential signaling cascade of MAP kinase and S6 kinase depends on 3′,5′-monophosphate concentration in Schwann cells: correlation to cellular differentiation and proliferation

    Article • Brain Research, November 1998, Elsevier

    Professor Tatsuro Mutoh

  73. NGF prevention of neurotoxicity induced by cisplatin, vincristine and taxol depends on toxicity of each drug and NGF treatment schedule:

    Article • Brain Research, June 1998, Elsevier

    Professor Tatsuro Mutoh

  74. GM1 gangliosidosis type 3 with severe jaw-closing impairment

    Article • Journal of the Neurological Sciences, November 1997, Elsevier

    Professor Tatsuro Mutoh

  75. Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

    Article • Journal of the Neurological Sciences, October 1997, Elsevier

    Professor Tatsuro Mutoh

  76. Discovery of ganglioside GM1 for normal function of Trk neurotrophin receptor in neuronal cells.

    Article • Proceedings of the National Academy of Sciences, May 1995, Proceedings of the National Academy of Sciences

    Professor Tatsuro Mutoh

  77. 1-Methyl-4-phenylpyridinum kills differentiated PC12 cells with a concomitant change in protein phosphorylation

    Article • Brain Research, October 1994, Elsevier

    Professor Tatsuro Mutoh

  78. Abundant but Inactive-state gpl40prototrkIs Expressed in Neuroblastomas of Patients with Good Prognosis

    Article • Japanese Journal of Cancer Research, January 1994, Wiley

    Professor Tatsuro Mutoh

  79. The Effect of the B Subunit of Cholera Toxin on the Action of Nerve Growth Factor on PC12 Cells

    Article • Journal of Neurochemistry, April 1993, Wiley

    Professor Tatsuro Mutoh

  80. A microassay for acid β-galactosidase activity toward asialofetuin

    Article • Clinica Chimica Acta, November 1985, Elsevier

    Professor Tatsuro Mutoh

  81. Application of a GM1 ganglioside β-galactosidase microassay method to diagnosis of GM1 gangliosidosis

    Article • Clinica Chimica Acta, July 1984, Elsevier

    Professor Tatsuro Mutoh

  82. A fluorometric microassay procedure for monitoring the enzymatic activity of GM1-ganglioside β-galactosidase by use of high-performance liquid chromatography

    Article • Analytical Biochemistry, July 1984, Elsevier

    Professor Tatsuro Mutoh