All Stories

  1. Discovery of pyranocoumarin derivatives as dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P-glycoprotein expression levels and function

    Article • Journal of Molecular Structure, August 2025, Elsevier

    Tarek Afifi

  2. A novel avenue in the successful synthesis of Schiff base macromolecules via innovative plasma and classical approaches

    Article • Scientific Reports, March 2025, Springer Science + Business Media

    Tarek Afifi

  3. Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, hCAII, and MMP-2 Inhibitors Based on Molecular Docking Assays

    Article • International Journal of Molecular Sciences, November 2023, MDPI AG

    Tarek Afifi

  4. DFT and In-silico Investigations, along with In-vitro Antitumor and Antimicrobial Assessments of Pharmacological Molecules

    Article • Current Organic Synthesis, August 2023, Bentham Science Publishers

    Mohamed El-Gaby, Tarek Afifi

  5. Synthesis of 9-Hydroxy-1H-Benzo[f]chromene Derivatives with Effective Cytotoxic Activity on MCF7/ADR, P-Glycoprotein Inhibitors, Cell Cycle Arrest and Apoptosis Effects

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Tarek Afifi

  6. Thermodynamic Parameters of Non-isothermal Degradation of a New Family of Organometallic Dendrimer with Isoconversional Methods

    Article • Journal of Inorganic and Organometallic Polymers and Materials, April 2022, Springer Science + Business Media

    Tarek Afifi

  7. Novel oxazolones incorporated azo dye: Design, synthesis photophysical-DFT aspects and antimicrobial assessments with In-silico and In-vitro surveys

    Article • Journal of Photochemistry and Photobiology, September 2021, Elsevier

    Tarek Afifi

  8. Novel 2-Hydroselenonicotinonitriles and Selenopheno[2, 3-b]pyridines: Efficient Synthesis, Molecular Docking-DFT Modeling, and Antimicrobial Assessment

    Article • Frontiers in Chemistry, May 2021, Frontiers

    Tarek Afifi, Prof. Mostafa A. Hussien

  9. A New Family of Benzo[h]Chromene Based Azo Dye: Synthesis, In-Silico and DFT Studies with In Vitro Antimicrobial and Antiproliferative Assessment

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    Tarek Afifi

  10. Antimicrobial screening and pharmacokinetic profiling of novel phenyl-[1,2,4]triazolo[4,3-a]quinoxaline analogues targeting DHFR and E. coli DNA gyrase B

    Article • Bioorganic Chemistry, March 2020, Elsevier

    Tarek Afifi, PhD Basem Awad Mansour

  11. Synthesis, Biological Assessment, and Structure Activity Relationship Studies of New Flavanones Embodying Chromene Moieties

    Article • Molecules, January 2020, MDPI AG

    Tarek Afifi

  12. A proficient microwave synthesis with structure elucidation and the exploitation of the biological behavior of the newly halogenated 3-amino-1H-benzo[f]chromene molecules, targeting dual inhibition of topoisomerase II and microtubules

    Article • Bioorganic Chemistry, January 2020, Elsevier

    Tarek Afifi

  13. Microwave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II

    Article • Bioorganic Chemistry, December 2019, Elsevier

    Tarek Afifi

  14. First example of Azo-Sulfa conjugated chromene moieties: Synthesis, characterization, antimicrobial assessment, docking simulation as potent class I histone deacetylase inhibitors and antitumor agents

    Article • Bioorganic Chemistry, November 2019, Elsevier

    Tarek Afifi

  15. First Example of Cationic Cyclopentadienyliron Based Chromene Complexes and Polymers: Synthesis, Characterization, and Biological Applications

    Article • Journal of Inorganic and Organometallic Polymers and Materials, August 2019, Springer Science + Business Media

    Tarek Afifi

  16. Novel chromenes and benzochromenes bearing arylazo moiety: molecular docking, in-silico admet, in-vitro antimicrobial and anticancer screening

    Article • Medicinal Chemistry Research, June 2019, Springer Science + Business Media

    Tarek Afifi

  17. Developing lipophilic aromatic halogenated fused systems with specific ring orientations, leading to potent anticancer analogs and targeting the c-Src Kinase enzyme

    Article • Journal of Molecular Structure, June 2019, Elsevier

    Tarek Afifi

  18. Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene

    Article • Bioorganic Chemistry, June 2019, Elsevier

    Tarek Afifi

  19. Design and Synthesis of Novel Heterocyclic-Based 4H-benzo[h]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis

    Article • Molecules, March 2019, MDPI AG

    Tarek Afifi

  20. Cell cycle arrest and induction of apoptosis of newly synthesized pyranoquinoline derivatives under microwave irradiation

    Article • Medicinal Chemistry Research, March 2019, Springer Science + Business Media

    Tarek Afifi

  21. Crystal Structure and Spectral Studies of 3-Amino-9-Methoxy-1-(4-methoxyphenyl)- 1H-Benzo[f]Chromene-2-Carbonitrile

    Article • Journal of Computational and Theoretical Nanoscience, June 2018, American Scientific Publishers

    Tarek Afifi

  22. Catalytic Activity of Sulfated and Phosphated Catalysts towards the Synthesis of Substituted Coumarin

    Article • Catalysts, January 2018, MDPI AG

    Tarek Afifi

  23. Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2018, Taylor & Francis

    Hany Ahmed, Tarek Afifi, Ahmed El-Agrody, Prof. Dr Ateyatallah Aljuhani

  24. Design, Synthesis, and Docking Studies of 4H-Chromene and Chromene Based Azo Chromophores: A Novel Series of Potent Antimicrobial and Anticancer Agents

    Article • Current Organic Synthesis, November 2017, Bentham Science Publishers

    Tarek Afifi, Hany Ahmed

  25. Design of Thermochromic Polynorbornene Bearing Spiropyran Chromophore Moieties: Synthesis, Thermal Behavior and Dielectric Barrier Discharge Plasma Treatment

    Article • Polymers, November 2017, MDPI AG

    Tarek Afifi

  26. Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3-Positions

    Article • Molecules, March 2017, MDPI AG

    Tarek Afifi

  27. cytotoxicity and SAR of Benzochromene derivatives

    Article • Zeitschrift für Naturforschung C, November 2016, De Gruyter

    Tarek Afifi

  28. Structural Characterization and Antimicrobial Activities of 7H-Benzo[h]chromeno[2,3-d]pyrimidine and 14H-Benzo[h]chromeno[3,2-e][1,2,4]triazolo[1,5-c] pyrimidine Derivatives

    Article • Molecules, November 2016, MDPI AG

    Tarek Afifi

  29. Homo- and Co-Polymers of Norbornene Containing Aryl- and Hetaryl-Azo Dyes; Synthesis and Sensing Properties

    Article • Macromolecular Chemistry and Physics, November 2009, Wiley

    Tarek Afifi

  30. One-bath dyeing of polyester/wool blend with disperse dyes

    Article • Journal of the Society of Dyers and Colourists, October 2008, Wiley

    Tarek Afifi

  31. A photochemical route to discrete, ternary metal chalcogenide clusters

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Tarek Afifi

  32. Novel azo disperse dyes derived from aminothiophenes: Synthesis and UV–visible studies

    Article • Dyes and Pigments, July 2006, Elsevier

    Tarek Afifi

  33. First Example of Benzothiazole Azo Dyes Containing Cyclopentadienyliron Polynorbornene Macromolecules

    Article • Journal of Inorganic and Organometallic Polymers and Materials, December 2004, Springer Science + Business Media

    Tarek Afifi

  34. Neutral and Cationic Cyclopentadienyliron Macromolecules Containing Arylazo Chromophores

    Article • Macromolecular Rapid Communications, August 2004, Wiley

    Tarek Afifi

  35. Organoiron polynorbornenes with pendent arylazo and hetarylazo dye moieties

    Article • Macromolecular Symposia, March 2004, Wiley

    Tarek Afifi

  36. Organoiron polymers containing azo dyes

    Article • Macromolecular Symposia, July 2003, Wiley

    Tarek Afifi

  37. A New Class of Cationic Organoiron Polynorbornenes Containing Azo Dyes

    Article • Macromolecular Chemistry and Physics, March 2003, Wiley

    Tarek Afifi

  38. Star-Shaped Polyaromatic Ethers Coordinated to Redox-Active Cyclopentadienyliron Moieties

    Article • Macromolecular Rapid Communications, January 2002, Wiley

    Tarek Afifi

  39. Remarkable effect of copper chloride on diiodination of zirconacyclopentadienes

    Article • Tetrahedron Letters, June 1997, Elsevier

    Tarek Afifi