All Stories

  1. Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential

    Article • Bioorganic Chemistry, April 2019, Elsevier

    Dr Susana Dias Lucas

  2. Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies

    Article • ACS Omega, December 2018, American Chemical Society (ACS)

    Professor Patrícia M Rijo, Dr Susana Dias Lucas

  3. Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2018, Elsevier

    Rui Moreira, Dr Luis F Gouveia, Dr Susana Dias Lucas

  4. Dipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in Aβ-Mediated Microglial Inflammation

    Article • ACS Chemical Neuroscience, January 2017, American Chemical Society (ACS)

    Rui Moreira, Dr Susana Dias Lucas

  5. Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes

    Article • ChemMedChem, July 2016, Wiley

    Rui Moreira, Dr Jose A Brito, Dr Susana Dias Lucas

  6. Wittig Reaction: Domino Olefination and Stereoselectivity DFT Study. Synthesis of the Miharamycins’ Bicyclic Sugar Moiety

    Article • Organic Letters, November 2015, American Chemical Society (ACS)

    Dr Susana Dias Lucas, Rafael Nunes

  7. Synthesis and Evaluation of the Biological Profile of Novel Analogues of Nucleosides and of Potential Mimetics of Sugar Phosphates and Nucleotides

    Article • Synlett, November 2015, Thieme Publishing Group

    Dr Susana Dias Lucas

  8. Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties

    Article • Journal of Lipid Research, September 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Susana Dias Lucas, Rui Moreira

  9. Activity-based probes as molecular tools for biomarker discovery

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Dr Susana Dias Lucas, Rui Moreira

  10. A unified approach toward the rational design of selective low nanomolar human neutrophil elastase inhibitors

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Susana Dias Lucas, Rui Moreira

  11. Discovery of C-shaped aurone human neutrophil elastase inhibitors

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Dr Susana Dias Lucas, Rui Moreira

  12. The Bile Acid-Sensitive Ion Channel (BASIC) Is Activated by Alterations of Its Membrane Environment

    Article • PLOS One, October 2014, PLOS

    Dr Susana Dias Lucas

  13. Convenient and chromatography-free partial syntheses of maslinic acid and augustic acid

    Article • Tetrahedron Letters, September 2014, Elsevier

    Dr Rene Csuk, Dr Susana Dias Lucas

  14. Amino derivatives of glycyrrhetinic acid as potential inhibitors of cholinesterases

    Article • Bioorganic & Medicinal Chemistry, July 2014, Elsevier

    Dr Rene Csuk, Dr Susana Dias Lucas

  15. P116 INTERACTION OF APOPTOTIC AND CYTOPROTECTIVE BILE ACIDS WITH BIOMEMBRANES

    Article • Journal of Hepatology, April 2014, Elsevier

    Dr Susana Dias Lucas

  16. Optimization of O 3 -Acyl Kojic Acid Derivatives as Potent and Selective Human Neutrophil Elastase Inhibitors

    Article • Journal of Medicinal Chemistry, December 2013, American Chemical Society (ACS)

    Dr Susana Dias Lucas, Rui Moreira

  17. Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, September 2013, Elsevier

    Dr Susana Dias Lucas, Rui Moreira

  18. Discovery of new heterocycles with activity against human neutrophile elastase based on a boron promoted one-pot assembly reaction

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Dr Susana Dias Lucas, Rui Moreira

  19. N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases

    Article • Bioorganic & Medicinal Chemistry Letters, June 2012, Elsevier

    Dr Susana Dias Lucas, Rui Moreira

  20. Structure based virtual screening for discovery of novel human neutrophil elastase inhibitors

    Article • MedChemComm, January 2012, Royal Society of Chemistry

    Dr Susana Dias Lucas, Rui Moreira

  21. Libraries on Oxetane δ-Amino Acid Scaffolds: Syntheses and Evaluation of Physicochemical and Metabolic Properties

    Article • Journal of Carbohydrate Chemistry, September 2011, Taylor & Francis

    Dr Susana Dias Lucas

  22. Targeting COPD: advances on low-molecular-weight inhibitors of human neutrophil elastase

    Article • Medicinal Research Reviews, June 2011, Wiley

    Dr Susana Dias Lucas, Rui Moreira

  23. Zeolites and Other Silicon-Based Promoters in Carbohydrate Chemistry

    Article • January 2010, Elsevier

    Dr Susana Dias Lucas

  24. Synthesis of 3-Fluoro-Oxetane δ-Amino Acids

    Article • Journal of Carbohydrate Chemistry, September 2009, Taylor & Francis

    Dr Susana Dias Lucas

  25. Zeolites as efficient catalysts for key transformations in carbohydrate chemistry

    Article • Journal of Molecular Catalysis A Chemical, June 2009, Elsevier

    Dr Susana Dias Lucas

  26. Synthesis of 3‐Methoxyoxetane δ‐Amino Acids with D‐lyxo, D‐ribo, and D‐arabino Configurations

    Article • Journal of Carbohydrate Chemistry, June 2008, Taylor & Francis

    Dr Susana Dias Lucas

  27. Alkyl deoxy-arabino-hexopyranosides: Synthesis, surface properties, and biological activities

    Article • Bioorganic & Medicinal Chemistry, April 2008, Elsevier

    Dr Susana Dias Lucas, Teacher Fernando J V Santos

  28. Oligosaccharide Mimetics

    Article • January 2008, Springer Science + Business Media

    Dr Susana Dias Lucas

  29. Acid zeolites as efficient catalysts for O- and S-glycosylation

    Article • Journal of Molecular Catalysis A Chemical, September 2007, Elsevier

    Dr Susana Dias Lucas

  30. Oxetane δ‐Amino Acids: Chemoenzymatic Synthesis of 2,4‐Anhydro‐5‐N‐(t‐butoxycarbonyl)amino‐D‐lyxonic Acid

    Article • Journal of Carbohydrate Chemistry, May 2006, Taylor & Francis

    Dr Susana Dias Lucas

  31. Synthesis, surface active and antimicrobial properties of new alkyl 2,6-dideoxy-l-arabino-hexopyranosides

    Article • Carbohydrate Research, February 2005, Elsevier

    Dr Susana Dias Lucas