All Stories

  1. A Double-Edged Sword: Thioxanthenes Act on Both the Mind and the Microbiome

    Article • Molecules, December 2021, MDPI AG

    Professor Stephen John Fey

  2. Biomechanics and Functional Tissue Engineering

    Article • November 2021, IntechOpen

    Professor Stephen John Fey

  3. Clinostat 3D Cell Culture: Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids

    Article • January 2021, Springer Science + Business Media

    Professor Stephen John Fey

  4. Response to and recovery from treatment in human liver-mimetic clinostat spheroids: a model for assessing repeated-dose drug toxicity

    Article • Toxicology Research, June 2020, Oxford University Press (OUP)

    Professor Stephen John Fey

  5. Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening

    Article • ACS Medicinal Chemistry Letters, April 2020, American Chemical Society (ACS)

    Professor Stephen John Fey

  6. A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model

    Article • Journal of Ethnopharmacology, July 2019, Elsevier

    Professor Stephen John Fey

  7. Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short term exposure to two-dimensional and three-dimensional spheroid cell cultures

    Article • Toxicology Mechanisms and Methods, June 2018, Taylor & Francis

    Professor Stephen John Fey

  8. Recent Advances in Three-Dimensional Cell Culturing to Assess Liver Function and Dysfunction: From a Drug Biotransformation and Toxicity Perspective

    Article • Toxicology Mechanisms and Methods, January 2018, Taylor & Francis

    Professor Stephen John Fey

  9. Proceedings - COST ACTION CM1407 2nd Training School

    Article • Biomedical and Biopharmaceutical Research, December 2017, ALIES

    Professor Stephen John Fey

  10. The Accepted “Clinical Interaction Model”: A Special Case of Reality

    Article • Journal of Bioequivalence & Bioavailability, January 2017, OMICS Publishing Group

    Professor Stephen John Fey

  11. Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids

    Article • Toxicology Research, January 2016, Oxford University Press (OUP)

    Professor Stephen John Fey

  12. A review of the potential offered by 3D cell culture

    Article • Current Pharmaceutical Design, November 2015, Bentham Science Publishers

    Professor Stephen John Fey

  13. Top-down and Middle-down Protein Analysis Reveals that Intact and Clipped Human Histones Differ in Post-translational Modification Patterns

    Article • Molecular & Cellular Proteomics, September 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Stephen John Fey

  14. Molar ratios of therapeutic water-soluble phenothiazine·water-insoluble phospholipid adducts reveal a Fibonacci correlation and a putative link for structure–activity relationships

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Professor Stephen John Fey

  15. The Cultural Divide: Exponential Growth in Classical 2D and Metabolic Equilibrium in 3D Environments

    Article • PLoS ONE, September 2014, PLOS

    Professor Stephen John Fey

  16. The relative abundance of proteins in complexes can be used as a measure of data quality.

    Article • PROTEOMICS, April 2014, Wiley

    Professor Stephen John Fey

  17. Z -2-(β- d -glucopyranosyloxy)-3-phenylpropenoic acid, an α-hydroxy acid from rooibos (Aspalathus linearis ) with hypoglycemic activity

    Article • Molecular Nutrition & Food Research, August 2013, Wiley

    Professor Stephen John Fey

  18. Microgravity spheroids as a reliable, long-term tool for predictive toxicology

    Article • Toxicology Letters, August 2013, Elsevier

    Professor Stephen John Fey

  19. HepG2/C3A 3D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsinisation

    Article • Toxicology Research, January 2013, Oxford University Press (OUP)

    Professor Stephen John Fey

  20. After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver

    Article • Toxicology Research, January 2013, Oxford University Press (OUP)

    Professor Stephen John Fey

  21. Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycemic potential

    Article • Phytomedicine, December 2012, Elsevier

    Professor Stephen John Fey

  22. Determination of Drug Toxicity Using 3D Spheroids Constructed From an Immortal Human Hepatocyte Cell Line

    Article • Toxicological Sciences, March 2012, Oxford University Press (OUP)

    Professor Stephen John Fey

  23. Similarities in expression levels of proteins in IL-1β stimulated BB-DP islets and islets syngrafted to BB-DP rats

    Article • Experimental and Clinical Endocrinology & Diabetes, July 2009, Thieme Publishing Group

    Professor Stephen John Fey

  24. Comparative proteome analysis of three mouse lung adenocarcinoma CMT cell lines with different metastatic potential by two-dimensional gel electrophoresis and mass spectrometry

    Article • PROTEOMICS, December 2008, Wiley

    Professor Stephen John Fey

  25. Assessing CMT cell line stability by two dimensional polyacrylamide gel electrophoresis and mass spectrometry based proteome analysis

    Article • Journal of Proteomics, July 2008, Elsevier

    Professor Stephen John Fey

  26. ID: 203 The Effects of Oral Contraceptives on Plasma - Studied by Proteomics.

    Article • Journal of Thrombosis and Haemostasis, October 2006, Elsevier

    Professor Stephen John Fey

  27. Proteome Profiling of Populus euphratica Oliv. Upon Heat Stress

    Article • Annals of Botany, June 2006, Oxford University Press (OUP)

    Professor Stephen John Fey

  28. Immune-mediated β-cell destruction in vitro and in vivo—A pivotal role for galectin-3

    Article • Biochemical and Biophysical Research Communications, May 2006, Elsevier

    Professor Stephen John Fey

  29. Different islet protein expression profiles during spontaneous diabetes development vs. allograft rejection in BB-DP rats

    Article • Autoimmunity, January 2006, Taylor & Francis

    Professor Stephen John Fey

  30. Changes in expression of IL-1� influenced proteins in transplanted islets during development of diabetes in diabetes-prone BB rats

    Article • Diabetologia, May 2004, Springer Science + Business Media

    Professor Stephen John Fey

  31. Transforming Growth Factor- 1 Specifically Induce Proteins Involved in the Myofibroblast Contractile Apparatus

    Article • Molecular & Cellular Proteomics, January 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Stephen John Fey

  32. Protein expression changes in a cell system of beta-cell maturation reflect an acquired sensitivity to IL-1?

    Article • Diabetologia, January 2004, Springer Science + Business Media

    Professor Stephen John Fey

  33. Intrauterine programming of fetal islet gene expression in rats?effects of maternal protein restriction during gestation revealed by proteome analysis

    Article • Diabetologia, November 2003, Springer Science + Business Media

    Professor Stephen John Fey

  34. Effect of acid shock on protein expression by biofilm cells of Streptococcus mutans

    Article • FEMS Microbiology Letters, October 2003, Oxford University Press (OUP)

    Professor Stephen John Fey

  35. Proteome Analysis Reveals Phosphorylation of ATP Synthase beta -Subunit in Human Skeletal Muscle and Proteins with Potential Roles in Type 2 Diabetes

    Article • Journal of Biological Chemistry, January 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Stephen John Fey

  36. IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

    Article • Diabetologia, November 2002, Springer Science + Business Media

    Professor Stephen John Fey

  37. Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence

    Article • Biochemical Pharmacology, September 2002, Elsevier

    Professor Stephen John Fey

  38. The effects of transcription regulating genesPDR1,pdr1-3 andPDR3 in pleiotropic drug resistance

    Article • PROTEOMICS, August 2001, Wiley

    Professor Stephen John Fey

  39. Proteome Analysis of Interleukin-1 -Induced Changes in Protein Expression in Rat Islets of Langerhans

    Article • Diabetes, May 2001, American Diabetes Association

    Professor Stephen John Fey

  40. Characterization of differently processed forms of enolase 2 fromSaccharomyces cerevisiae by two-dimensional gel electrophoresis and mass spectrometry

    Article • Electrophoresis, February 2001, Wiley

    Professor Stephen John Fey

  41. 2D or not 2D

    Article • Current Opinion in Chemical Biology, February 2001, Elsevier

    Professor Stephen John Fey

  42. The effects of transcription regulating genes PDR1, pdr1-3 and PDR3 in pleiotropic drug resistance

    Article • European Journal of Mass Spectrometry, January 2001, IM Publications

    Professor Stephen John Fey

  43. Comparison of the Proteomes of Three Yeast Wild Type Strains: CEN.PK2, FY1679 and W303

    Article • Comparative and Functional Genomics, January 2001, Hindawi Publishing Corporation

    Professor Stephen John Fey

  44. Cytokine- or chemically derived nitric oxide alters the expression of proteins detected by two-dimensional gel electrophoresis in neonatal rat islets of Langerhans

    Article • Diabetes, November 2000, American Diabetes Association

    Professor Stephen John Fey

  45. Towards higher resolution: Two-dimensional Electrophoresis of Saccharomyces cerevisiae proteins using overlapping narrow immobilized pH gradients

    Article • Electrophoresis, July 2000, Wiley

    Professor Stephen John Fey

  46. Islet Protein Expression Changes during Diabetes Development in Islet Syngrafts in BB-DP Rats and during Rejection of BB-DP Islet Allografts

    Article • Autoimmunity, January 2000, Taylor & Francis

    Professor Stephen John Fey

  47. Two-dimensional gel analysis of human endometrial proteins: characterization of proteins with increased expression in hyperplasia and adenocarcinoma

    Article • Molecular Human Reproduction, August 1999, Oxford University Press (OUP)

    Professor Stephen John Fey

  48. Comparison of yeast cell protein solubilization procedures for two-dimensional electrophoresis

    Article • Electrophoresis, January 1999, Wiley

    Professor Stephen John Fey

  49. Correlation of acidic and basic carrier ampholyte and immobilized pH gradient two-dimensional gel electrophoresis patterns based on mass spectrometric protein identification

    Article • Electrophoresis, May 1998, Wiley

    Professor Stephen John Fey

  50. Proteome analysis ofSaccharomyces cerevisiae: A methodological outline

    Article • Electrophoresis, January 1997, Wiley

    Professor Stephen John Fey

  51. Interleukin-1β induced changes in the protein expression of rat islets: A computerized database

    Article • Electrophoresis, January 1997, Wiley

    Professor Stephen John Fey

  52. Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes.

    Article • Journal of Clinical Investigation, June 1996, American Society for Clinical Investigation

    Professor Stephen John Fey

  53. Cloning and expression of cytokine-inducible nitric oxide synthase cDNA from rat islets of Langerhans

    Article • Diabetes, July 1995, American Diabetes Association

    Professor Stephen John Fey

  54. Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide

    Article • Diabetes, April 1995, American Diabetes Association

    Professor Stephen John Fey

  55. Interlaboratory reproducibility of yeast protein patterns analyzed by immobilized pH gradient two-dimensional gel electrophoresis

    Article • Electrophoresis, January 1995, Wiley

    Professor Stephen John Fey

  56. Human endometrial proteins with cyclic changes in the expression during the normal menstrual cycle: characterization by protein sequence analysis

    Article • Molecular Human Reproduction, January 1995, Oxford University Press (OUP)

    Professor Stephen John Fey

  57. Morphological differentiation and changes in polypeptide synthesis pattern during regeneration of human epidermal tissue developed in vitro

    Article • Differentiation, May 1991, Elsevier

    Professor Stephen John Fey

  58. Chlamydia trachomatis contains a protein similar to the Legionella pneumophila mip gene product

    Article • Molecular Microbiology, January 1991, Wiley

    Professor Stephen John Fey

  59. No effect of intralesional injection of interferon on moderate cervical intraepithelial neoplasia

    Article • BJOG An International Journal of Obstetrics & Gynaecology, July 1990, Wiley

    Professor Stephen John Fey

  60. Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen

    Article • Diabetes, September 1989, American Diabetes Association

    Professor Stephen John Fey

  61. Demonstration of In Vitro Synthesis of Human Papilloma Viral Proteins from Hand and Foot Warts

    Article • Journal of Investigative Dermatology, June 1989, Elsevier

    Professor Stephen John Fey

  62. Human papilloma virus (HPV) and carcinomas of the head and neck

    Article • Clinical Otolaryngology, December 1988, Wiley

    Professor Stephen John Fey

  63. DNA viruses and human cancer☆

    Article • Cancer Letters, July 1988, Elsevier

    Professor Stephen John Fey

  64. An animal model for investigating transforming properties of human papilloma virus

    Article • Cancer Letters, July 1987, Elsevier

    Professor Stephen John Fey

  65. Cervical lesions express the suspected transforming proteins of HPV

    Article • Cancer Letters, July 1987, Elsevier

    Professor Stephen John Fey

  66. The type of human papillomavirus present in cervical infections can be determined by the occurrence of specific marker proteins

    Article • Cell Biology International Reports, November 1986, Wiley

    Professor Stephen John Fey

  67. Preferential Phosphorylation of Keratins and Vimentin During Mitosis in Normal and Transformed Human Amnion Cells

    Article • Annals of the New York Academy of Sciences, October 1985, Wiley

    Professor Stephen John Fey

  68. Expression of the transformation-sensitive protein "cyclin" in normal human epidermal basal cells and simian virus 40-transformed keratinocytes.

    Article • Proceedings of the National Academy of Sciences, May 1984, Proceedings of the National Academy of Sciences

    Professor Stephen John Fey

  69. Intermediate filaments in monkey kidney TC7 cells: focal centers and interrelationship with other cytoskeletal systems.

    Article • Proceedings of the National Academy of Sciences, February 1984, Proceedings of the National Academy of Sciences

    Professor Stephen John Fey

  70. Cyclin: A nuclear protein whose level correlates directly with the proliferative state of normal as well as transformed cells

    Article • Leukemia Research, January 1984, Elsevier

    Professor Stephen John Fey

  71. Phosphorylation of keratin and vimentin polypeptides in normal and transformed mitotic human epithelial amnion cells: behavior of keratin and vimentin filaments during mitosis

    Article • The Journal of Cell Biology, November 1983, Rockefeller University Press

    Professor Stephen John Fey

  72. Evidence for coordinated phosphorylation of keratins and vimentin during mitosis in transformed human amnion cells

    Article • FEBS Letters, June 1983, Wiley

    Professor Stephen John Fey

  73. Differential immunological crossreactivity of HeLa keratin antibodies with human epidermal keratins.

    Article • Proceedings of the National Academy of Sciences, April 1983, Proceedings of the National Academy of Sciences

    Professor Stephen John Fey

  74. Proteins IEF (isoelectric focusing) 31 and IEF 46 are keratin-type components of the intermediate-sized filaments: keratins of various human cultured epithelial cells

    Article • The Journal of Cell Biology, February 1983, Rockefeller University Press

    Professor Stephen John Fey

  75. Mouse mitochondrial protein IEF 24: Identification and immunohistochemical localization of mitochondria in various tissues

    Article • Electrophoresis, February 1983, Wiley

    Professor Stephen John Fey

  76. Putative association of mitochondria with a subpopulation of intermediate-sized filaments in cultured human skin fibroblasts

    Article • Cell, December 1982, Elsevier

    Professor Stephen John Fey

  77. More than one-third of the discernible mouse polypeptides are not expressed in a Chinese hamster-mouse embryo fibroblast hybrid that retains all mouse chromosomes.

    Article • Proceedings of the National Academy of Sciences, April 1982, Proceedings of the National Academy of Sciences

    Professor Stephen John Fey

  78. Architecture and polypeptide composition of HeLa cytoskeletons

    Article • Journal of Molecular Biology, January 1982, Elsevier

    Professor Stephen John Fey

  79. Identification of a nuclear and of a cytoplasmic polypeptide whose relative proportions are sensitive to changes in the rate of cell proliferation

    Article • Experimental Cell Research, December 1981, Elsevier

    Professor Stephen John Fey

  80. Coexistence of three major isoactins in a single sarcoma 180 cell

    Article • Cell, July 1981, Elsevier

    Professor Stephen John Fey

  81. [S]-methionine labelled polypeptides from secondary mouse kidney fibroblasts: Coordinates and one dimensional peptide maps of some major polypeptides

    Article • Cell Biology International Reports, May 1981, Wiley

    Professor Stephen John Fey

  82. Gene expression in murine hybrids exhibiting different morphologies and tumorigenic properties

    Article • Carcinogenesis, January 1981, Oxford University Press (OUP)

    Professor Stephen John Fey

  83. Transcription of globin genes in reticulocyte chromatin

    Article • FEBS Letters, September 1979, Wiley

    Professor Stephen John Fey

  84. Chapter 33. The Assay of Globin Gene Transcription in Reconstituted Chromatin

    Article • January 1978, Elsevier

    Professor Stephen John Fey