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- Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity
Article
- Combination of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate for the treatment of inflammatory lung diseases: An in vitro study
Article
- Moringa oleifera Leaf Extracts as Multifunctional Ingredients for “Natural and Organic” Sunscreens and Photoprotective Preparations
Article
- Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study
- A Multitarget Approach for Photoprotection and Prevention of Sun Exposure Related Damage
- Herbal extracts, lichens and biomolecules as natural photo-protection alternatives to synthetic UV filters. A systematic review
- Antidermatophytic Action of Resorcinol Derivatives: Ultrastructural Evidence of the Activity of Phenylethyl Resorcinol against Microsporum gypseum
- New insights into sugar characterization in complex plant matrices by high-performance thin-layer chromatography
Article
- Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones
Article
- Reactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified Derivatives
Article
- Phloridzin derivatives inhibiting pro-inflammatory cytokine expression in human cystic fibrosis IB3-1 cells
- Corrigendum to “Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors” [Eur. J. Med. Chem. 101 (2015) 573–583]
Article
- Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors
- A Multi-Target Approach toward the Development of Novel Candidates for Antidermatophytic Activity: Ultrastructural Evidence on α-Bisabolol-Treated Microsporum gypseum
- Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties
- Retraction notice to: “Design, synthesis, and antioxidant potency of novel α-tocopherol analogues in isolated membranes and intact cells” [Free Radical Biology & Medicine 44 (2008) 1452–1464]
Article
- Encapsulation of Satureja montana essential oil in β-cyclodextrin
- High-Performance Thin-Layer Chromatography (HPTLC): a New Green Approach to Soluble Fiber Determination in Plant Matrices
- Evaluation of Antiradical Activity of Different Cocoa and Chocolate Products: Relation with Lipid and Protein Composition
- Interaction and reactivity of synthetic aminoisoflavones with metal-free and metal-associated amyloid-β
- Antioxidant Activity of Cosmetic Formulations Based on Novel Extracts from Seeds of Brazilian <i>Araucaria angustifolia</i> (Bertoll) Kuntze
- Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features
- Frataxin mRNA Isoforms in FRDA Patients and Normal Subjects: Effect of Tocotrienol Supplementation
- Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water
- Dualistic Properties of Cosmetic Formulations Based on Phenylpropanoids from <i>Ajuga reptans</i>
- Synthesis, Antioxidant and Antimicrobial Activity of a New Phloridzin Derivative for Dermo-Cosmetic Applications
Article
- Synthesis and in vitro stability of nucleoside 5′-phosphonate derivatives
Article
- Synthetic Studies toward C-Glucosidic Ellagitannins: A Biomimetic Total Synthesis of 5-O-Desgalloylepipunicacortein A
- Novel molecular combination deriving from natural aminoacids and polyphenols: Design, synthesis and free-radical scavenging activities
- ChemInform Abstract: Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-piperazine.
- Activity and Stability Studies of Verbascoside, a Novel Antioxidant, in Dermo-Cosmetic and Pharmaceutical Topical Formulations
- Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-Piperazine
- Antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomesin vitro
- Pyrazolo[3,4-c]isothiazole and isothiazolo[4,3-d]isoxazole derivatives as antifungal agents
- Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress
- Synthesis of 3-azabicyclo[4.1.0]heptane-1-carboxylic acid
- ChemInform Abstract: A New Synthetic Approach to Pyrazolo[3,4-c]-1,2,5-oxadiazoles.
- ChemInform Abstract: Design, Synthesis and Enzymatic Activity of Highly Selective Human Mitochondrial Thymidine Kinase Inhibitors.
- First synthesis of 2,6-diazabicyclo[3.2.0]heptane derivatives
- Quorum sensing inhibition activity of garlic extract andp-coumaric acid
- Carnitine Conjugate of Nipecotic Acid: A New Example of Dual Prodrug
- ChemInform Abstract: 7-Deazainosine Derivatives: Synthesis and Characterization of 7- and 7,8-Substituted Pyrrolo[2,3-d]pyrimidine Ribonucleosides.
- Progress in Drug Delivery to the Central Nervous System by the Prodrug Approach
- 7-Deazainosine Derivatives: Synthesis and Characterization of 7- and 7,8-Substituted Pyrrolo [2,3-d]Pyrimidine Ribonucleosides
- RETRACTED: Design, synthesis, and antioxidant potency of novel α-tocopherol analogues in isolated membranes and intact cells
- New Coordination Modes ofL-Ascorbic Acid and Dehydro-L-ascorbic Acid as Dianionic Chelating Ligand for Platinum
- Design, Synthesis and Anti Flaviviridae Activity of N6-, 5′,3′-O- and 5′,2′-O-Substituted Adenine Nucleoside Analogs
- Effects of new combinative antioxidant FeAOX-6 and α-tocotrienol on macrophage atherogenesis-related functions
- Protective effects of Fe-Aox29, a novel antioxidant derived from a molecular combination of Idebenone and vitamin E, in immortalized fibroblasts and fibroblasts from patients with Friedreich Ataxia
- Novel selective human mitochondrial kinase inhibitors: Design, synthesis and enzymatic activity
- Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer
- The use of photochemiluminescence for the measurement of the integral antioxidant capacity of baobab products
- A non-invasive method for the in vivo determination of skin antioxidant capacity (IAC-S�)
- Design, synthesis and in vivo activity of 9-(S)-dihydroerythromycin derivatives as potent anti-inflammatory agents
- Comparative antioxidant activity of tocotrienols and the novel chromanyl-polyisoprenyl molecule FeAox-6 in isolated membranes and intact cells
- Nanoparticle formulation may affect the stabilization of an antiischemic prodrug
- Antioxidant effect of FeAOX-6 on free radical species produced during iron catalyzed breakdown oftert-butyl hydroperoxide
- Hypolipidaemic activity of aqueous ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property
- Adenosine Phosphonoacetic Acid is Slowly Metabolized by NDP Kinase
- Synthetic Approaches to a Mononucleotide Prodrug of Cytarabine
- Comparative evaluation of 11 essential oils of different origin as functional antioxidants, antiradicals and antimicrobials in foods
- Synthesis and biological evaluation of pro-drugs of GW196771, a potent glycine antagonist acting at the NMDA receptor
- Development and characterization of biodegradable nanospheres as delivery systems of anti-ischemic adenosine derivatives
- Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs
- Vitamin C and 6-amino-vitamin C conjugates of diclofenac: synthesis and evaluation
- In vitro neuroprotection by novel antioxidants in guinea-pig urinary bladder subjected to anoxia-glucopenia/reperfusion damage
- Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules
- Composition and Functional Properties of the Essential Oil of Amazonian Basil,Ocimum micranthumWilld., Labiatae in Comparison with Commercial Essential Oils
- The Antioxidants and Pro-Antioxidants Network: An Overview
- Hindered nucleoside analogs as antiflaviviridae agents
- Transporter-Mediated Effects of Diclofenamic Acid and its Ascorbyl Pro-Drug in the in Vivo Neurotropic Activity of Ascorbyl Nipecotic Acid Conjugate
- Determination of antioxidant efficacy of cosmetic formulations by non-invasive measurements
- Capillary Electrophoresis Determination, Synthesis, and Stability of Resveratrol and Related 3- O -β- d -Glucopyranosides
- Design, synthesis, and antioxidant activity of FeAOX-6, a novel agent deriving from a molecular combination of the chromanyl and polyisoprenyl moieties
- Adenosine A1 Receptor: Analysis of the Potential Therapeutic Effects Obtained by its Activation in the Central Nervous System
- Design, Synthesis and Activity of Ascorbic Acid Prodrugs of Nipecotic, Kynurenic and Diclophenamic Acids, Liable to Increase Neurotropic Activity
- Design, Synthesis and Enzymatic Activity of Highly Selective Human Mitochondrial Thymidine Kinase Inhibitors
- 2′-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase
- Novel antioxidant agents deriving from molecular combinations of vitamins C and E analogues: 3,4-dihydroxy-5(R)-[2(R,S)-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2(R,S)-yl-methyl)-[1,3]dioxolan-4(S)-yl]-5H-furan-2-one and 3-O-octadecyl derivatives
- ChemInform Abstract: Pyrazole Related Nucleosides. Part 5. Synthesis and Biological Activity of 2′-Deoxy-2′,3′-dideoxy- and Acyclo-Analogues of 4-Iodo-1-β-D-ribofuranosyl-3-carboxymethylpyrazole (IPCAR).
- Pyrazolo-triazoles as light activable dna cleaving agents
- Design, synthesis and binding at cloned muscarinic receptors of N-[5-(1′-substituted-acetoxymethyl)-3-oxadiazolyl] and N-[4-(1′-substituted-acetoxymethyl)-2-dioxolanyl] dialkyl amines
- Pyrazole Related Nucleosides 5.1Synthesis and Biological Activity of 2′-Deoxy- 2′, 3′-dideoxy- and Acyclo-analogues of 4-Iodo-1-β-D-ribofuranosyl-3-carboxymethyl Pyrazole (IPCAR)
- Peptide T-araC conjugates: solid-phase synthesis and biological activity of N4-(acylpeptidyl)-araC
- A New Synthetic Approach to Pyrazolo[3,4-c]-1,2,5-oxadiazoles
- Synthesis, in Vitro Antiproliferative Activity, and DNA-Binding Properties of Hybrid Molecules Containing Pyrrolo[2,1- c ][1,4]benzodiazepine and Minor-Groove-Binding Oligopyrrole Carriers
- Heterocyclic Derivatives ofall-transRetinoic Acid:in vitroEffects on Fibroblast/Keratinocyte Growth and Differentiation, andin vivoEffects on Guinea-Pig Skin
- 5‘-Phosphoramidates and 5‘-Diphosphates of 2‘- O -Allyl-β- d -arabinofuranosyl- uracil, -cytosine, and -adenine: Inhibition of Ribonucleotide Reductase
- Prodrugs of Ara-CMP and Ara-AMP with aS-Acyl-2-thioethyl (SATE) Biolabile Phosphate Protecting Group: Synthesis and Biological Evaluation
- Synthesis, Cytostatic Activity and Inhibition of Ribonucleotide Reductase by 5′-Phosphoramidates and 5′-Diphosphates, of 2′-O-Allyl-arabinofuranosyl Nucleosides
- Synthesis and Anti-HSV-1 Activity of 6 Substituted Pyrazolo[3,4-d]Pyridazin-7-one Nucleosides
- A Mild One-Pot Synthesis of Thieno[3,4-c]pyrazoles and Their Conversion into Pyrazole Analogs of o-Quinodimethane
- Synthesis and Biological Evaluation of a Series of Substituted Pyrazolo[3,4-d]-1,2,3-triazoles and Pyrazolo[3,4-d]oxazoles
- Synthesis and Biological Evaluation of a Series of Substituted Pyrazolo[3,4-d]-1,2,3-triazoles and Pyrazolo[3,4-d]oxazoles
- Retinoic Acid Conjugates as Potential Antitumor Agents: Synthesis and Biological Activity of Conjugates with Ara-A, Ara-C, 3(2 H )-Furanone, and Aniline Mustard Moieties
- Facile synthesis of 2-nitroalkanols by tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones
- Synthesis and antiproliferative activity of 2′-O-allyl-1-β-D-arabinofuranosyl-uracil, -cytosine and -adenine
- De Novo Biosynthesis of Purines
- Prevention of Free Radical Oxidative Damage
- Synthesis of the 6- and 7-hydroxylated cocaines and pseudococaines
- Design, synthesis and antiproliferative activity of methyl 4-Iodo-1-β-D-ribofuranosyl-pyrazole-3-carboxylate and related compounds
- A PLE-based resolution of cocaine, pseudococaine, and 6- and 7-methoxylated cocaine analogues
- Unusual Ring-Opening Reaction of 6,7-Dihydrothieno[3,2-d]pyrimidine-2,4-dione Derivatives Leading to 5-(Alkylthio)-6-vinyluracils
- Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl- and 8-ethynyladenosine
- Cholinergic Agents Structurally Related to Furtrethonium. 2. Synthesis and Antimuscarinic Activity of a Series of N-[5-[(1'-Substituted-acetoxy)methyl]-2-furfuryl]dialkylamines
- Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines
- Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c] pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists.
- A one-pot glycosylation of tetrahydropyranyl (THP) ether intermediates
- Geiparvarin Analogs. 4.1. Synthesis and Cytostatic Activity of Geiparvarin Analogs Bearing a Carbamate Moiety or a Furocoumarin Fragment on the Alkenyl Side Chain
- A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives
- Cholinergic agents structurally related to furtrethonium. 1
- Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs)
- An unusual trimethylsilyltriflate catalyzed transformation of 6-[3-aryl-2-hydroxypropyl]-4,5-dihydro-3(2-pyridazinones into 3-(1-naphthyl)propionic acid esters
- Facile access to 2′-O-acyl prodrugs of 1- (β-d-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil (BVAraU) via regioselective esterase-catalyzed hydrolysis of 2′ 3′, 5′-triesters1
- An Efficient Synthesis of 4-Oxo-2,5-hexadienoates via Δ 2 -Isoxazoline Intermediates
- Geiparvarin Analogs. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain.
- Regio - and enantioselective bioreduction of ethyl 2,4-dioxoalkanoates and γ-Keto-α-enamino esters with fermenting baker's yeast
- Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides
- Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates
- Nucleic acid related compounds. 65. New syntheses of 1-(.beta.-D-arabinofuranosyl)-5(E)-(2-iodovinyl)uracil (IVAraU) from vinylsilane precursors. Radioiodine uptake as a marker for thymidine kinase herpes viral infections
- Ha-ras-1 Transfected Cells: Induction to Differentiation by Natural and Synthetic Retinoids
- A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin.
- Synthesys of Isoxazole and Isoxazoline Derivatives of Retinoids: Effects on Growth and Differentiation of Tumor Cells
- Synthèse de quelques dérivés isoxazoliques analogues des rétinoides. Effects biologiques vis-à-vis des cellules tumorales
- Conversion of vinylsilanes to vinyl halides with xenon difluoride and metal halides. A versatile new route to 5-(2-halovinyl)pyrimidine nucleosides
- Synthesis and cytostatic activity of geiparvarin analogs
- 3,4-Bismethylenecyclopentanone ethylene ketal: A useful diene for[6.5]ring systems: Application to a formal synthesis of gibberellic acid
- A [3+2] nitrile oxide cycloaddition approach to retinoids
- A convenient synthesis of λ-oxo-acrylates
- Isoxazoles-mediated synthesis of geiparvarin and dihydrogeiparvarin
- Synthesis and reactivity of a stable precursor of 2-cyano-1,3-butadiene
- Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H) furanones and 3(2H) furanimines
- Synthesis and Interaction of 5-(Substituted-phenyl)-3-methy1-6,7-dihydropyrazolo[4,3-e][1,4]diazepin-8(7H)-ones with Benzodiazepine Receptors in Rat Cerebral Cortex
- A new nitrile oxide based synthesis of the antitumor agent geiparvarin
- Pyrazolo[4,3-d]pyrimidine nucleosides. Synthesis and antiviral activity of 1-.beta.-D-ribofuranosyl-3-methyl-6-substituted-7H-pyrazolo[4,3-d]pyrimidin-7-ones
- Ethyl 5-substituted-3-isoxazolecarboxylates as starting materials for a convenient route to 3(2H)furanones and 3(2H)iminofuranes.
- Preparation of 3,4-Dihydroxy-1-benzeneethanol: A Reinvestigation