All Stories

  1. Toward indole postbiotics precision therapy via AI-powered drug delivery technologies
  2. Preface
  3. Enteric delivery of indole-3-carboxylic acid unlocks therapeutic potential of postbiotic metabolite cascade
  4. Updates on Candida albicans infections: pathogenesis, resistance, and emerging nanopharmaceutical strategies
  5. Comparative Proteomic Analysis of Extracellular Vesicles from Donkey Colostrum and Mature Milk
  6. Corrigendum: Nickel oxide nanoparticles exposure as a risk factor for male infertility: “In vitro” effects on porcine pre-pubertal Sertoli cells
  7. Correction: Gambelunghe et al. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity. Antioxidants 2020, 9, 697
  8. Exploring Sertoli Cells’ Innate Bulwark Role Against Infections: In Vitro Performances on Candida tropicalis Biofilms
  9. Cross-Kingdom Communication via Plant-Derived Extracellular Vesicle Nucleic Acids in Genetically Engineered Nicotiana tabacum
  10. Pomegranate peel extract as a sustainable plant protection agent against Xanthomonas campestris pv. campestris: mechanisms and applications
  11. Preface
  12. Initial Development of Automated Machine Learning-Assisted Prediction Tools for Aryl Hydrocarbon Receptor Activators
  13. Human and gut microbiota synergy in a metabolically active superorganism: a cardiovascular perspective
  14. Strategies and delivery systems for cell-based therapy in autoimmunity
  15. Protective Effect of Indole-3-Aldehyde in Murine COVID-19-Associated Pulmonary Aspergillosis
  16. The immune and microbial homeostasis determines theCandida–mast cells cross-talk in celiac disease
  17. Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches
  18. A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis
  19. Biologics, theranostics, and personalized medicine in drug delivery systems
  20. Preface
  21. Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study
  22. A Stable Micellar Formulation of RAD001 for Intracerebroventricular Delivery and the Treatment of Alzheimer’s Disease and Other Neurological Disorders
  23. Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines
  24. A Thermostable Micellar Formulation of Rapalogs for Intracerebroventricular Delivery and the Therapy of Neurological Disorders
  25. Evaluation of β-Lactamase Enzyme Activity in Outer Membrane Vesicles (OMVs) Isolated from Extended Spectrum β-Lactamase (ESBL) Salmonella Infantis Strains
  26. Nickel oxide nanoparticles exposure as a risk factor for male infertility: “In vitro” effects on porcine pre-pubertal Sertoli cells
  27. Boosting Immunity and Management against Wheat Fusarium Diseases by a Sustainable, Circular Nanostructured Delivery Platform
  28. Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract
  29. Preface
  30. Sustainable Protocols for Cellulose Nanocrystals Synthesis from Tomato Waste and Their Antimicrobial Properties against Pseudomonas syringae pv. tomato
  31. Extracellular Vesicles in Aging: An Emerging Hallmark?
  32. Turning Microbial AhR Agonists into Therapeutic Agents via Drug Delivery Systems
  33. Biodrug Delivery Systems: Do mRNA Lipid Nanoparticles Come of Age?
  34. Development of a new indole derivative dry powder for inhalation for the treatment of biofilm-associated lung infections
  35. Pulmonary drug delivery technology enables anakinra repurposing in cystic fibrosis
  36. Development and Pharmacokinetics of a Novel Acetylsalicylic Acid Dry Powder for Pulmonary Administration
  37. Aryl Hydrocarbon Receptor Agonism Antagonizes the Hypoxia-driven Inflammation in Cystic Fibrosis
  38. General Guide to Publish a Scientific Paper
  39. Pharmaceutically Active Microbial AhR Agonists as Innovative Biodrugs in Inflammation
  40. Circular Hazelnut Protection by Lignocellulosic Waste Valorization for Nanopesticides Development
  41. Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite
  42. Preface
  43. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy
  44. Effects of Titanium Dioxide Nanoparticles on Porcine Prepubertal Sertoli Cells: An “In Vitro” Study
  45. SBA15-supported nano-ruthenium catalyst for the oxidative cleavage of alkenes to aldehydes under flow conditions
  46. Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers
  47. Defective Glyoxalase 1 Contributes to Pathogenic Inflammation in Cystic Fibrosis
  48. Preface
  49. Dry Powder Inhalers in the Digitalization Era: Current Status and Future Perspectives
  50. Development and in vitro-in vivo performances of an inhalable indole-3-carboxaldehyde dry powder to target pulmonary inflammation and infection
  51. Rojo Duro Red Onion Extract Loaded Spray Thermogel as a Sustainable Platform for the Treatment of Oral Mucosa Lesions
  52. A Green Nanostructured Pesticide to Control Tomato Bacterial Speck Disease
  53. Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients
  54. Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis
  55. Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting
  56. Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity
  57. Regulation of host physiology and immunity by microbial indole-3-aldehyde
  58. Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome
  59. Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi
  60. Tackling Immune Pathogenesis of COVID-19 through Molecular Pharmaceutics
  61. Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
  62. Optimized Extraction of Amikacin from Murine Whole Blood
  63. Initial In Vivo Evaluation of a Novel Amikacin-Deoxycholate Hydrophobic Salt Delivers New Insights on Amikacin Partition in Blood and Tissues
  64. In “Vitro” Lps-Stimulated Sertoli Cells Pre-Loaded With Microparticles: Intracellular Activation Pathways
  65. Selectively targeting key inflammatory pathways in cystic fibrosis
  66. Evolutionary Algorithms in Modeling Aerodynamic Properties of Spray-Dried Microparticulate Systems
  67. Meet Our Editorial Board Member
  68. Preface
  69. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity
  70. Postbiotic-Enabled Targeting of the Host-Microbiota-Pathogen Interface: Hints of Antibiotic Decline?
  71. Tryptophan as a Central Hub for Host/Microbial Symbiosis
  72. An Inhalable Theranostic System for Local Tuberculosis Treatment Containing an Isoniazid Loaded Metal Organic Framework Fe-MIL-101-NH2—From Raw MOF to Drug Delivery System
  73. Phenotypic Characterization of Rhodococcus equi Biofilm Grown In Vitro and Inhibiting and Dissolving Activity of Azithromycin/Rifampicin Treatment
  74. Development and characterization of mucoadhesive-thermoresponsive gels for the treatment of oral mucosa diseases
  75. Preface
  76. Meeting the unmet: from traditional to cutting-edge techniques for poly lactide and poly lactide-co-glycolide microparticle manufacturing
  77. Exploring the Nano Spray-Drying Technology as an Innovative Manufacturing Method for Solid Lipid Nanoparticle Dry Powders
  78. Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease
  79. Probing Internalization Effects and Biocompatibility of Ultrasmall Zirconium Metal-Organic Frameworks UiO-66 NP in U251 Glioblastoma Cancer Cells
  80. A Novel Stabilizing Approach to Improve the Manufacturing of Biodegradable Microparticles Entrapping Plasticizing Active Molecules: the Case of 4-Methoxychalcone
  81. Development of Novel Indole-3-Aldehyde–Loaded Gastro-Resistant Spray-Dried Microparticles for Postbiotic Small Intestine Local Delivery
  82. In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment
  83. Reply to ‘F508del-CFTR is not corrected by thymosin α1’
  84. Testosterone and FSH modulate Sertoli cell extracellular secretion: Proteomic analysis
  85. Crystallization
  86. Physical Properties Characterization
  87. Biopharmaceutical Processes
  88. Particle Size Measurement
  89. Pharmaceutical Powder and Particles
  90. Solid-State Chemistry
  91. General Conclusion
  92. Introduction
  93. Towards Targeting the Aryl Hydrocarbon Receptor in Cystic Fibrosis
  94. Fundamentals of Particle Interactions
  95. Particle Size and Distribution
  96. Recent and Evolving Manufacturing Processes
  97. Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile
  98. Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms
  99. TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells
  100. The long and winding road to inhaled TB therapy: not only the bug’s fault
  101. Extremely Active, Tunable, and pH-Responsive Iridium Water Oxidation Catalysts
  102. Ion Pairing for Controlling Drug Delivery
  103. Rapamycin-loaded solid lipid nanoparticles: Morphology and impact of the drug loading on the phase transition between lipid polymorphs
  104. Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
  105. Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice
  106. β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing
  107. Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice
  108. Drug delivery system innovation and Health Technology Assessment: Upgrading from Clinical to Technological Assessment
  109. Alginate beads as a carrier for omeprazole/SBA-15 inclusion compound: A step towards the development of personalized paediatric dosage forms
  110. Alginates in Pharmaceutics and Biomedicine: Is the Future so Bright?
  111. Powder, capsule and device: An imperative ménage à trois for respirable dry powders
  112. Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy
  113. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions
  114. Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3‐dioxygenase1
  115. Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard
  116. Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation
  117. In vitro–in vivo correlation from lactide-co-glycolide polymeric dosage forms
  118. Microparticle-loaded neonatal porcine Sertoli cells for cell-based therapeutic and drug delivery system
  119. Chitosan films containing mesoporous SBA-15 supported silver nanoparticles for wound dressing
  120. Capreomycin inhalable powders prepared with an innovative spray-drying technique
  121. The Influence of Feedstock and Process Variables on the Encapsulation of Drug Suspensions by Spray‐Drying in Fast Drying Regime: The Case of Novel Antitubercular Drug–Palladium Complex Containing Polymeric Microparticles
  122. Development of Risperidone PLGA Microspheres
  123. IVIVC from Long Acting Olanzapine Microspheres
  124. Synthesis, characterization and in vitro extracellular and intracellular activity against Mycobacterium tuberculosis infection of new second-line antitubercular drug-palladium complexes
  125. Lipid nanoparticles for brain targeting II. Technological characterization
  126. Preparation, Characterization, and In Vivo Evaluation of Olanzapine Poly(D,L-lactide-co-glycolide) Microspheres
  127. Capreomycin supergenerics for pulmonary tuberculosis treatment: Preparation, in vitro, and in vivo characterization
  128. Colloidal nickel(0)-carboxymethyl cellulose particles: A biopolymer-inorganic catalyst for hydrogenation of nitro-aromatics and carbonyl compounds
  129. Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin–palladium complex
  130. Conformal polymer coatings for pancreatic islets transplantation
  131. Response to Comment on Blasi et al. (2011) “Lipid nanoparticles for brain targeting I. Formulation optimization”
  132. Synthesis of colloidal dispersions of NiAl, ZnAl, NiCr, ZnCr, NiFe, and MgFe hydrotalcite-like nanoparticles
  133. The real value of novel particulate carriers for sunscreen formulation
  134. Lipid nanoparticles for brain targeting I. Formulation optimization
  135. Solid Lipid Nanoparticles to Improve Brain Drug Delivery
  136. Development of a scalable procedure for fine calcium alginate particle preparation
  137. Formulation and Release Behavior of Doxycycline–Alginate Hydrogel Microparticles Embedded into Pluronic F127 Thermogels as a Potential New Vehicle for Doxycycline Intradermal Sustained Delivery
  138. Simple and scalable method for peptide inhalable powder production
  139. Bioactive Long-Term Release from Biodegradable Microspheres Preserves Implanted ALG-PLO-ALG Microcapsules from In Vivo Response to Purified Alginate
  140. Fighting tuberculosis: old drugs, new formulations
  141. Lipid Nanoparticles for Drug Delivery to the Brain: In Vivo Veritas
  142. Formulation studies of benzydamine mucoadhesive formulations for vaginal administration
  143. Novel composite microparticles for protein stabilization and delivery
  144. Eudragit® and hydrotalcite-like anionic clay composite system for diclofenac colonic delivery
  145. Influence of Compression Force on The Behavior of Mucoadhesive Buccal Tablets
  146. Physicochemical characterization and release mechanism of a novel prednisone biodegradable microsphere formulation
  147. Solid Lipid Nanoparticles for Targeted Brain Drug Delivery
  148. Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate
  149. Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen
  150. Modification of theophylline release with alginate gel formed in hard capsules
  151. Solid lipid nanoparticles for targeted brain drug delivery☆
  152. Ketoprofen poly(lactide-co-glycolide) physical interaction
  153. Preparation of large porous biodegradable microspheres by using a simple double-emulsion method for capreomycin sulfate pulmonary delivery
  154. Preparation and in vitro and in vivo characterization of composite microcapsules for cell encapsulation
  155. Delivering Drugs to the Central Nervous System: A Medicinal Chemistry or a Pharmaceutical Technology Issue?
  156. Development of liposomal capreomycin sulfate formulations: Effects of formulation variables on peptide encapsulation
  157. Evaluation and Optimization of the Conditions for an Improved Ferulic Acid Intercalation into a Synthetic Lamellar Anionic Clay
  158. Ketoprofen controlled release from composite microcapsules for cell encapsulation: Effect on post-transplant acute inflammation
  159. Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters
  160. Evaluation of Indomethacin Percutaneous Absorption from Nanostructured Lipid Carriers (NLC): In Vitro and In Vivo Studies
  161. Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery
  162. UV spectroscopy and reverse-phase HPLC as novel methods to determine Capreomycin of liposomal fomulations
  163. Development of mucoadhesive patches for buccal administration of ibuprofen
  164. Potential prodrugs of non-steroidal anti-inflammatory agents for targeted drug delivery to the CNS
  165. Leucinostatin-A loaded nanospheres: characterization and in vivo toxicity and efficacy evaluation
  166. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
  167. Unilamellar vesicles as potential capreomycin sulfate carriers: Preparation and physicochemical characterization
  168. Multifunctional microcapsules for pancreatic islet cell entrapment: design, preparation and in vitro characterization
  169. Preparation and characterization of poly(D,L-lactide-co-glycolide) microspheres for controlled release of human growth hormone