All Stories

  1. Unlocking Matricaria chamomilla bioactives: Process optimization via betaine-NADES extraction, metabolic profiling, and antityrosinase activity
  2. A novel spray-dried milk extracellular vesicles formulation with long-term immunomodulatory activity and functional stability
  3. Toward indole postbiotics precision therapy via AI-powered drug delivery technologies
  4. Preface
  5. Enteric delivery of indole-3-carboxylic acid unlocks therapeutic potential of postbiotic metabolite cascade
  6. Updates on Candida albicans infections: pathogenesis, resistance, and emerging nanopharmaceutical strategies
  7. Comparative Proteomic Analysis of Extracellular Vesicles from Donkey Colostrum and Mature Milk
  8. Corrigendum: Nickel oxide nanoparticles exposure as a risk factor for male infertility: “In vitro” effects on porcine pre-pubertal Sertoli cells
  9. Correction: Gambelunghe et al. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity. Antioxidants 2020, 9, 697
  10. Exploring Sertoli Cells’ Innate Bulwark Role Against Infections: In Vitro Performances on Candida tropicalis Biofilms
  11. Cross-Kingdom Communication via Plant-Derived Extracellular Vesicle Nucleic Acids in Genetically Engineered Nicotiana tabacum
  12. Pomegranate peel extract as a sustainable plant protection agent against Xanthomonas campestris pv. campestris: mechanisms and applications
  13. Preface
  14. Initial Development of Automated Machine Learning-Assisted Prediction Tools for Aryl Hydrocarbon Receptor Activators
  15. Human and gut microbiota synergy in a metabolically active superorganism: a cardiovascular perspective
  16. Strategies and delivery systems for cell-based therapy in autoimmunity
  17. Protective Effect of Indole-3-Aldehyde in Murine COVID-19-Associated Pulmonary Aspergillosis
  18. The immune and microbial homeostasis determines theCandida–mast cells cross-talk in celiac disease
  19. Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches
  20. A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis
  21. Biologics, theranostics, and personalized medicine in drug delivery systems
  22. Preface
  23. Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study
  24. A Stable Micellar Formulation of RAD001 for Intracerebroventricular Delivery and the Treatment of Alzheimer’s Disease and Other Neurological Disorders
  25. Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines
  26. A Thermostable Micellar Formulation of Rapalogs for Intracerebroventricular Delivery and the Therapy of Neurological Disorders
  27. Evaluation of β-Lactamase Enzyme Activity in Outer Membrane Vesicles (OMVs) Isolated from Extended Spectrum β-Lactamase (ESBL) Salmonella Infantis Strains
  28. Nickel oxide nanoparticles exposure as a risk factor for male infertility: “In vitro” effects on porcine pre-pubertal Sertoli cells
  29. Boosting Immunity and Management against Wheat Fusarium Diseases by a Sustainable, Circular Nanostructured Delivery Platform
  30. Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract
  31. Preface
  32. Sustainable Protocols for Cellulose Nanocrystals Synthesis from Tomato Waste and Their Antimicrobial Properties against Pseudomonas syringae pv. tomato
  33. Extracellular Vesicles in Aging: An Emerging Hallmark?
  34. Turning Microbial AhR Agonists into Therapeutic Agents via Drug Delivery Systems
  35. Biodrug Delivery Systems: Do mRNA Lipid Nanoparticles Come of Age?
  36. Development of a new indole derivative dry powder for inhalation for the treatment of biofilm-associated lung infections
  37. Pulmonary drug delivery technology enables anakinra repurposing in cystic fibrosis
  38. Development and Pharmacokinetics of a Novel Acetylsalicylic Acid Dry Powder for Pulmonary Administration
  39. Aryl Hydrocarbon Receptor Agonism Antagonizes the Hypoxia-driven Inflammation in Cystic Fibrosis
  40. General Guide to Publish a Scientific Paper
  41. Pharmaceutically Active Microbial AhR Agonists as Innovative Biodrugs in Inflammation
  42. Circular Hazelnut Protection by Lignocellulosic Waste Valorization for Nanopesticides Development
  43. Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite
  44. Preface
  45. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy
  46. Effects of Titanium Dioxide Nanoparticles on Porcine Prepubertal Sertoli Cells: An “In Vitro” Study
  47. SBA15-supported nano-ruthenium catalyst for the oxidative cleavage of alkenes to aldehydes under flow conditions
  48. Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers
  49. Defective Glyoxalase 1 Contributes to Pathogenic Inflammation in Cystic Fibrosis
  50. Preface
  51. Dry Powder Inhalers in the Digitalization Era: Current Status and Future Perspectives
  52. Development and in vitro-in vivo performances of an inhalable indole-3-carboxaldehyde dry powder to target pulmonary inflammation and infection
  53. Rojo Duro Red Onion Extract Loaded Spray Thermogel as a Sustainable Platform for the Treatment of Oral Mucosa Lesions
  54. A Green Nanostructured Pesticide to Control Tomato Bacterial Speck Disease
  55. Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients
  56. Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis
  57. Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting
  58. Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity
  59. Regulation of host physiology and immunity by microbial indole-3-aldehyde
  60. Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome
  61. Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi
  62. Tackling Immune Pathogenesis of COVID-19 through Molecular Pharmaceutics
  63. Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
  64. Optimized Extraction of Amikacin from Murine Whole Blood
  65. Initial In Vivo Evaluation of a Novel Amikacin-Deoxycholate Hydrophobic Salt Delivers New Insights on Amikacin Partition in Blood and Tissues
  66. In “Vitro” Lps-Stimulated Sertoli Cells Pre-Loaded With Microparticles: Intracellular Activation Pathways
  67. Selectively targeting key inflammatory pathways in cystic fibrosis
  68. Evolutionary Algorithms in Modeling Aerodynamic Properties of Spray-Dried Microparticulate Systems
  69. Meet Our Editorial Board Member
  70. Preface
  71. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity
  72. Postbiotic-Enabled Targeting of the Host-Microbiota-Pathogen Interface: Hints of Antibiotic Decline?
  73. Tryptophan as a Central Hub for Host/Microbial Symbiosis
  74. An Inhalable Theranostic System for Local Tuberculosis Treatment Containing an Isoniazid Loaded Metal Organic Framework Fe-MIL-101-NH2—From Raw MOF to Drug Delivery System
  75. Phenotypic Characterization of Rhodococcus equi Biofilm Grown In Vitro and Inhibiting and Dissolving Activity of Azithromycin/Rifampicin Treatment
  76. Development and characterization of mucoadhesive-thermoresponsive gels for the treatment of oral mucosa diseases
  77. Preface
  78. Meeting the unmet: from traditional to cutting-edge techniques for poly lactide and poly lactide-co-glycolide microparticle manufacturing
  79. Exploring the Nano Spray-Drying Technology as an Innovative Manufacturing Method for Solid Lipid Nanoparticle Dry Powders
  80. Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease
  81. Probing Internalization Effects and Biocompatibility of Ultrasmall Zirconium Metal-Organic Frameworks UiO-66 NP in U251 Glioblastoma Cancer Cells
  82. A Novel Stabilizing Approach to Improve the Manufacturing of Biodegradable Microparticles Entrapping Plasticizing Active Molecules: the Case of 4-Methoxychalcone
  83. Development of Novel Indole-3-Aldehyde–Loaded Gastro-Resistant Spray-Dried Microparticles for Postbiotic Small Intestine Local Delivery
  84. In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment
  85. Reply to ‘F508del-CFTR is not corrected by thymosin α1’
  86. Testosterone and FSH modulate Sertoli cell extracellular secretion: Proteomic analysis
  87. Crystallization
  88. Physical Properties Characterization
  89. Biopharmaceutical Processes
  90. Particle Size Measurement
  91. Pharmaceutical Powder and Particles
  92. Solid-State Chemistry
  93. General Conclusion
  94. Introduction
  95. Towards Targeting the Aryl Hydrocarbon Receptor in Cystic Fibrosis
  96. Fundamentals of Particle Interactions
  97. Particle Size and Distribution
  98. Recent and Evolving Manufacturing Processes
  99. Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile
  100. Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms
  101. TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells
  102. The long and winding road to inhaled TB therapy: not only the bug’s fault
  103. Extremely Active, Tunable, and pH-Responsive Iridium Water Oxidation Catalysts
  104. Ion Pairing for Controlling Drug Delivery
  105. Rapamycin-loaded solid lipid nanoparticles: Morphology and impact of the drug loading on the phase transition between lipid polymorphs
  106. Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
  107. Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice
  108. β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing
  109. Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice
  110. Drug delivery system innovation and Health Technology Assessment: Upgrading from Clinical to Technological Assessment
  111. Alginate beads as a carrier for omeprazole/SBA-15 inclusion compound: A step towards the development of personalized paediatric dosage forms
  112. Alginates in Pharmaceutics and Biomedicine: Is the Future so Bright?
  113. Powder, capsule and device: An imperative ménage à trois for respirable dry powders
  114. Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy
  115. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions
  116. Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3‐dioxygenase1
  117. Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard
  118. Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation
  119. In vitro–in vivo correlation from lactide-co-glycolide polymeric dosage forms
  120. Microparticle-loaded neonatal porcine Sertoli cells for cell-based therapeutic and drug delivery system
  121. Chitosan films containing mesoporous SBA-15 supported silver nanoparticles for wound dressing
  122. Capreomycin inhalable powders prepared with an innovative spray-drying technique
  123. The Influence of Feedstock and Process Variables on the Encapsulation of Drug Suspensions by Spray‐Drying in Fast Drying Regime: The Case of Novel Antitubercular Drug–Palladium Complex Containing Polymeric Microparticles
  124. Development of Risperidone PLGA Microspheres
  125. IVIVC from Long Acting Olanzapine Microspheres
  126. Synthesis, characterization and in vitro extracellular and intracellular activity against Mycobacterium tuberculosis infection of new second-line antitubercular drug-palladium complexes
  127. Lipid nanoparticles for brain targeting II. Technological characterization
  128. Preparation, Characterization, and In Vivo Evaluation of Olanzapine Poly(D,L-lactide-co-glycolide) Microspheres
  129. Capreomycin supergenerics for pulmonary tuberculosis treatment: Preparation, in vitro, and in vivo characterization
  130. Colloidal nickel(0)-carboxymethyl cellulose particles: A biopolymer-inorganic catalyst for hydrogenation of nitro-aromatics and carbonyl compounds
  131. Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin–palladium complex
  132. Conformal polymer coatings for pancreatic islets transplantation
  133. Response to Comment on Blasi et al. (2011) “Lipid nanoparticles for brain targeting I. Formulation optimization”
  134. Synthesis of colloidal dispersions of NiAl, ZnAl, NiCr, ZnCr, NiFe, and MgFe hydrotalcite-like nanoparticles
  135. The real value of novel particulate carriers for sunscreen formulation
  136. Lipid nanoparticles for brain targeting I. Formulation optimization
  137. Solid Lipid Nanoparticles to Improve Brain Drug Delivery
  138. Development of a scalable procedure for fine calcium alginate particle preparation
  139. Formulation and Release Behavior of Doxycycline–Alginate Hydrogel Microparticles Embedded into Pluronic F127 Thermogels as a Potential New Vehicle for Doxycycline Intradermal Sustained Delivery
  140. Simple and scalable method for peptide inhalable powder production
  141. Bioactive Long-Term Release from Biodegradable Microspheres Preserves Implanted ALG-PLO-ALG Microcapsules from In Vivo Response to Purified Alginate
  142. Fighting tuberculosis: old drugs, new formulations
  143. Lipid Nanoparticles for Drug Delivery to the Brain: In Vivo Veritas
  144. Formulation studies of benzydamine mucoadhesive formulations for vaginal administration
  145. Novel composite microparticles for protein stabilization and delivery
  146. Eudragit® and hydrotalcite-like anionic clay composite system for diclofenac colonic delivery
  147. Influence of Compression Force on The Behavior of Mucoadhesive Buccal Tablets
  148. Physicochemical characterization and release mechanism of a novel prednisone biodegradable microsphere formulation
  149. Solid Lipid Nanoparticles for Targeted Brain Drug Delivery
  150. Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate
  151. Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen
  152. Modification of theophylline release with alginate gel formed in hard capsules
  153. Solid lipid nanoparticles for targeted brain drug delivery☆
  154. Ketoprofen poly(lactide-co-glycolide) physical interaction
  155. Preparation of large porous biodegradable microspheres by using a simple double-emulsion method for capreomycin sulfate pulmonary delivery
  156. Preparation and in vitro and in vivo characterization of composite microcapsules for cell encapsulation
  157. Delivering Drugs to the Central Nervous System: A Medicinal Chemistry or a Pharmaceutical Technology Issue?
  158. Development of liposomal capreomycin sulfate formulations: Effects of formulation variables on peptide encapsulation
  159. Evaluation and Optimization of the Conditions for an Improved Ferulic Acid Intercalation into a Synthetic Lamellar Anionic Clay
  160. Ketoprofen controlled release from composite microcapsules for cell encapsulation: Effect on post-transplant acute inflammation
  161. Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters
  162. Evaluation of Indomethacin Percutaneous Absorption from Nanostructured Lipid Carriers (NLC): In Vitro and In Vivo Studies
  163. Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery
  164. UV spectroscopy and reverse-phase HPLC as novel methods to determine Capreomycin of liposomal fomulations
  165. Development of mucoadhesive patches for buccal administration of ibuprofen
  166. Potential prodrugs of non-steroidal anti-inflammatory agents for targeted drug delivery to the CNS
  167. Leucinostatin-A loaded nanospheres: characterization and in vivo toxicity and efficacy evaluation
  168. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
  169. Unilamellar vesicles as potential capreomycin sulfate carriers: Preparation and physicochemical characterization
  170. Multifunctional microcapsules for pancreatic islet cell entrapment: design, preparation and in vitro characterization
  171. Preparation and characterization of poly(D,L-lactide-co-glycolide) microspheres for controlled release of human growth hormone