All Stories

  1. Evaluating the Performance of Hyperspectral Imaging Endoscopes: Mitigating Parameters Affecting Spectral Accuracy

    Article • Biosensors, November 2025, MDPI AG

    Dr Silas Leavesley

  2. A Case Study of Integrating AI Literacy Education in a Biology Class

    Article • International Journal of Artificial Intelligence in Education, April 2025, Springer Science + Business Media

    Dr Silas Leavesley

  3. Evaluating Normalization Methods for Robust Spectral Performance Assessments of Hyperspectral Imaging Cameras

    Article • Biosensors, January 2025, MDPI AG

    Dr Silas Leavesley

  4. Comparing Performance of Spectral Image Analysis Approaches for Detection of Cellular Signals in Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy

    Article • Bioengineering, May 2023, MDPI AG

    Dr Silas Leavesley

  5. Data from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  6. Data from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  7. Supplemental Figure 1 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  8. Supplemental Figure 1 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  9. Supplemental Figure 2A from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  10. Supplemental Figure 2A from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  11. Supplemental Figure 2B from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  12. Supplemental Figure 2B from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  13. Supplemental Figure 2C from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  14. Supplemental Figure 2C from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  15. Supplemental Figure 3A from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  16. Supplemental Figure 3A from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  17. Supplemental Figure 3B from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  18. Supplemental Figure 3B from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  19. Supplemental Figure 3C from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  20. Supplemental Figure 3C from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  21. Supplemental Figure 4A from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  22. Supplemental Figure 4A from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  23. Supplemental Figure 4B from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  24. Supplemental Figure 4B from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  25. Supplemental Figure 4C from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  26. Supplemental Figure 4C from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  27. Supplemental Figure 5 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  28. Supplemental Figure 5 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  29. Supplemental Figure 6 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  30. Supplemental Figure 6 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  31. Supplemental Figure 7 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  32. Supplemental Figure 7 from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  33. Supplemental Figure Legends from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  34. Supplemental Figure Legends from Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • April 2023, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  35. Endoscopy Lifetime Systems Architecture: Scoping Out the Past to Diagnose the Future Technology

    Article • Systems, October 2022, MDPI AG

    Dr Silas Leavesley

  36. Microscopy is better in color: development of a streamlined spectral light path for real-time multiplex fluorescence microscopy

    Article • Biomedical Optics Express, June 2022, Optical Society of America (OSA)

    Dr Silas Leavesley

  37. Suppression of Colon Tumorigenesis in MutantApcMice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin

    Article • Cancer Prevention Research, September 2021, American Association for Cancer Research (AACR)

    Dr Silas Leavesley

  38. Excitation-scanning hyperspectral video endoscopy: enhancing the light at the end of the tunnel

    Article • Biomedical Optics Express, December 2020, Optical Society of America (OSA)

    Dr Silas Leavesley

  39. Cystatin C regulates the cytotoxicity of infection‐induced endothelial‐derived β‐amyloid

    Article • FEBS Open Bio, October 2020, Wiley

    Dr Silas Leavesley

  40. Development of an endothelial cell-restricted transgenic reporter rat: a resource for physiological studies of vascular biology

    Article • AJP Heart and Circulatory Physiology, August 2020, American Physiological Society

    Dr Silas Leavesley

  41. Front Cover: Label‐free spectroscopic tissue characterization using fluorescence excitation‐scanning spectral imaging (J. Biophotonics 2/2020)

    Article • Journal of Biophotonics, February 2020, Wiley

    Dr Silas Leavesley

  42. Label‐free spectroscopic tissue characterization using fluorescence excitation‐scanning spectral imaging

    Article • Journal of Biophotonics, October 2019, Wiley

    Dr Silas Leavesley

  43. Human ASIC1a mediates stronger acid‐induced responses as compared with mouse ASICIa

    Article • The FASEB Journal, February 2018, Wiley

    Dr Silas Leavesley, Mike Lin

  44. Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids

    Article • The FASEB Journal, March 2017, Federation of American Societies For Experimental Biology (FASEB)

    Dr Silas Leavesley, Chun Zhou, Brant Wagener

  45. Hyperspectral imaging fluorescence excitation scanning for colon cancer detection

    Article • Journal of Biomedical Optics, October 2016, SPIE

    Dr Silas Leavesley

  46. Excitation-scanning hyperspectral imaging system for microscopic and endoscopic applications

    Article • April 2016, SPIE

    Dr Silas Leavesley

  47. Feasibility for detection of autofluorescent signatures in rat organs using a novel excitation-scanning hyperspectral imaging system

    Article • April 2016, SPIE

    Dr Silas Leavesley

  48. Overcoming limitations of FRET measurements

    Article • Cytometry Part A, April 2016, Wiley

    Dr Silas Leavesley

  49. Three-dimensional measurement of cAMP gradients using hyperspectral confocal microscopy

    Article • March 2016, SPIE

    Dr Silas Leavesley

  50. Hyperspectral imaging fluorescence excitation scanning for detecting colorectal cancer: pilot study

    Article • March 2016, SPIE

    Dr Silas Leavesley

  51. LED-based endoscopic light source for spectral imaging

    Article • March 2016, SPIE

    Dr Silas Leavesley

  52. Modification of Fibers with Nanostructures Using Reactive Dye Chemistry

    Article • Industrial & Engineering Chemistry Research, April 2015, American Chemical Society (ACS)

    Dr Silas Leavesley

  53. Automated Image Analysis of FRET Signals for Subcellular cAMP Quantification

    Article • January 2015, Springer Science + Business Media

    Dr Silas Leavesley

  54. Channel-Based Reporters for cAMP Detection

    Article • January 2015, Springer Science + Business Media

    Dr Silas Leavesley

  55. FRET: Signals hidden within the noise

    Article • Cytometry Part A, September 2014, Wiley

    Dr Silas Leavesley

  56. A Device for Performing Automated Balloon Catheter Inflation Ischemia Studies

    Article • PLOS One, April 2014, PLOS

    Dr Silas Leavesley

  57. Excitation-scanning hyperspectral imaging microscope

    Article • Journal of Biomedical Optics, April 2014, SPIE

    Dr Silas Leavesley

  58. Can we decipher the information content contained within cyclic nucleotide signals?

    Article • Journal of General Physiology, December 2013, Rockefeller University Press

    Dr Silas Leavesley

  59. Thin-film tunable filters for hyperspectral fluorescence microscopy

    Article • Journal of Biomedical Optics, September 2013, SPIE

    Dr Silas Leavesley

  60. An Approach for Characterizing and Comparing Hyperspectral Microscopy Systems

    Article • Sensors, July 2013, MDPI AG

    Dr Silas Leavesley

  61. Assessing FRET using spectral techniques

    Article • Cytometry Part A, July 2013, Wiley

    Dr Silas Leavesley

  62. The Feasibility of Using Millimeter Wave Heating for Non-Invasive Measurement of Skin Blood Flow in Humans

    Article • June 2013, ASME International

    Dr Silas Leavesley

  63. Linear unmixing of hyperspectral images for analysis of fluorescently-labeled cellswith imperfect endmember spectra

    Article • April 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Silas Leavesley

  64. Tunable thin-film optical filters for hyperspectral microscopy

    Article • February 2013, SPIE

    Dr Silas Leavesley

  65. Hyperspectral Imaging of FRET-Based cGMP Probes

    Article • January 2013, Springer Science + Business Media

    Dr Silas Leavesley

  66. Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells

    Article • AJP Cell Physiology, November 2011, American Physiological Society

    Dr Silas Leavesley

  67. Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue

    Article • Journal of Biophotonics, October 2011, Wiley

    Dr Silas Leavesley

  68. Assessment Of The Contributions Of Phosphodiesterase Activity And Cellular Shape To The Compartmentalization Of Camp Signals - A Computational Study

    Article • May 2011, American Thoracic Society

    Dr Silas Leavesley

  69. A Spectral Imaging Method For Monitoring Infused Endothelial Progenitor Cell Distribution In Normal Lung

    Article • May 2011, American Thoracic Society

    Dr Silas Leavesley

  70. State of the Art in Information Extraction and Quantitative Analysis for Multimodality Biomolecular Imaging

    Article • Proceedings of the IEEE, March 2008, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Silas Leavesley

  71. Hyperspectral small animal fluorescence imaging: spectral selection imaging

    Article • February 2008, SPIE

    Dr Silas Leavesley

  72. A calibrated tissue phantom for small animal fluorescence imaging

    Article • February 2008, SPIE

    Dr Silas Leavesley

  73. An endoscope for simultaneous macroscopic navigation and microscopic inspection of luminal sidewalls

    Article • February 2008, SPIE

    Dr Silas Leavesley

  74. An excitation wavelength–scanning spectral imaging system for preclinical imaging

    Article • Review of Scientific Instruments, January 2008, American Institute of Physics

    Dr Silas Leavesley

  75. Design of a wavelength-tunable light source using an acousto-optic tunable filter

    Article • September 2007, SPIE

    Dr Silas Leavesley

  76. Application of quantitative morphological cytometry for evaluation of shear stress: potential for HCS systems

    Article • February 2007, SPIE

    Dr Silas Leavesley

  77. Modeling in vivo fluorescence of small animals using TracePro software

    Article • February 2007, SPIE

    Dr Silas Leavesley

  78. Quantification of morphology of bacterial colonies using laser scatter measurements and solid element optical modeling

    Article • February 2007, SPIE

    Dr Silas Leavesley

  79. Sol-gel derived materials as substrates for neuronal differentiation: effects of surface features and protein conformation

    Article • Journal of Materials Chemistry, January 2006, Royal Society of Chemistry

    Dr Silas Leavesley

  80. Multispectral imaging analysis: spectral deconvolution and applications in biology

    Article • March 2005, SPIE

    Dr Silas Leavesley