All Stories

  1. Gut bacteria enriched in obese mice produce leucic acid to counter obesity through HCAR2

    Article • November 2025, Springer Science + Business Media

    Dr. Shu-Yong Lin

  2. Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

    Article • Molecular Oncology, February 2025, Wiley

    Dr. Shu-Yong Lin

  3. HuR promotes triglyceride synthesis and intestinal fat absorption

    Article • Cell Reports, May 2024, Elsevier

    Dr. Shu-Yong Lin

  4. Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance

    Article • Frontiers in Neuroscience, April 2024, Frontiers

    Dr. Shu-Yong Lin

  5. BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes

    Article • Journal of Molecular Cell Biology, May 2023, Oxford University Press (OUP)

    Dr. Shu-Yong Lin

  6. Pancreatic Brsk2 amplifies parasympathetic signals to promote type 2 diabetes

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Dr. Shu-Yong Lin

  7. AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1

    Article • Nature Cell Biology, March 2021, Springer Science + Business Media

    Dr. Shu-Yong Lin

  8. SRC promotes lipogenesis: implications for obesity and breast cancer

    Article • Molecular & Cellular Oncology, January 2021, Taylor & Francis

    Dr. Shu-Yong Lin

  9. Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy

    Article • Nature Communications, November 2020, Springer Science + Business Media

    Dr. Shu-Yong Lin

  10. Carbohydrates: Not All that Bad?

    Article • Cell Metabolism, November 2018, Elsevier

    Dr. Shu-Yong Lin

  11. Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate

    Article • Nature Communications, May 2018, Springer Science + Business Media

    Dr. Shu-Yong Lin

  12. Reply

    Article • Hepatology, April 2018, Wiley

    Dr. Shu-Yong Lin

  13. Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury

    Article • Hepatology, April 2018, Wiley

    Dr. Shu-Yong Lin

  14. AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity

    Article • Cell Metabolism, April 2018, Elsevier

    Dr. Shu-Yong Lin

  15. ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy

    Article • Molecular Cell, May 2016, Elsevier

    Dr. Shu-Yong Lin

  16. Structure and mechanism of the unique C2 domain of Aida

    Article • FEBS Journal, September 2014, Wiley

    Dr. Shu-Yong Lin

  17. Mechanism and Physiological Significance of Growth Factor-Related Autophagy

    Article • Physiology, November 2013, American Physiological Society

    Dr. Shu-Yong Lin

  18. PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation

    Article • PLOS One, November 2012, PLOS

    Dr. Shu-Yong Lin

  19. Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy

    Article • Autophagy, September 2012, Taylor & Francis

    Dr. Shu-Yong Lin

  20. GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

    Article • Science, April 2012, American Association for the Advancement of Science

    Dr. Shu-Yong Lin

  21. Revealing a steroid receptor ligand as a unique PPARγ agonist

    Article • BDJ, October 2011, Springer Science + Business Media

    Dr. Shu-Yong Lin

  22. Identification of Novel SNPs by Next-Generation Sequencing of the Genomic Region Containing theAPCGene in Colorectal Cancer Patients in China

    Article • OMICS A Journal of Integrative Biology, June 2010, Mary Ann Liebert Inc

    Dr. Shu-Yong Lin

  23. Axin determines cell fate by controlling the p53 activation threshold after DNA damage

    Article • Nature Cell Biology, August 2009, Springer Science + Business Media

    Dr. Shu-Yong Lin

  24. Asymmetric Syntheses and Wnt Signal Inhibitory Activity of Melleumin A and Four Analogues of Melleumins A and B

    Article • Chemistry - An Asian Journal, January 2009, Wiley

    Dr. Shu-Yong Lin

  25. CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5

    Article • FEBS Letters, March 2008, Wiley

    Dr. Shu-Yong Lin

  26. A β-Catenin-Independent Dorsalization Pathway Activated by Axin/JNK Signaling and Antagonized by Aida

    Article • Developmental Cell, August 2007, Elsevier

    Dr. Shu-Yong Lin

  27. Tob1 Controls Dorsal Development of Zebrafish Embryos by Antagonizing Maternal β-Catenin Transcriptional Activity

    Article • Developmental Cell, August 2006, Elsevier

    Dr. Shu-Yong Lin

  28. Axin is a scaffold protein in TGF-β signaling that promotes degradation of Smad7 by Arkadia

    Article • The EMBO Journal, April 2006, Wiley

    Dr. Shu-Yong Lin

  29. Axin Contains Three Separable Domains That Confer Intramolecular, Homodimeric, and Heterodimeric Interactions Involved in Distinct Functions

    Article • Journal of Biological Chemistry, February 2005, Elsevier

    Dr. Shu-Yong Lin

  30. Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation

    Article • The EMBO Journal, November 2004, Wiley

    Dr. Shu-Yong Lin, Zhenguo Wu