All Stories

  1. Lipid Scrambling Pathways in the Sec61 Translocon Complex

    Article • Journal of the American Chemical Society, May 2025, American Chemical Society (ACS)

    Dr Sarah O'Keefe

  2. Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

    Article • eLife, January 2025, eLife

    Dr Sarah O'Keefe

  3. The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

    Article • iScience, November 2023, Elsevier

    Dr Sarah O'Keefe

  4. Dual Action of Eeyarestatin 24 on Sec-Dependent Protein Secretion and Bacterial DNA

    Article • ACS Infectious Diseases, January 2023, American Chemical Society (ACS)

    Dr Sarah O'Keefe

  5. Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting

    Article • Cells, September 2022, MDPI AG

    Prof Martin Jung, Dr Sarah O'Keefe

  6. Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F

    Article • Molecules, July 2022, MDPI AG

    Wei Shi, Belinda Hall, Dr Sarah O'Keefe

  7. Biochemical and Biological Assays of Mycolactone-Mediated Inhibition of Sec61

    Article • October 2021, Springer Science + Business Media

    Dr Sarah O'Keefe

  8. An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum

    Article • Communications Biology, July 2021, Springer Science + Business Media

    Dr Sarah O'Keefe, Wei Shi

  9. How are membrane proteins made? A road-map for cell biologists.

    Article • European Journal of Biochemistry, June 2021, Wiley

    Dr Sarah O'Keefe

  10. Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis

    Article • Scientific Reports, June 2021, Springer Science + Business Media

    Dr Sarah O'Keefe, Wei Shi

  11. First person – Sarah O'Keefe

    Article • Journal of Cell Science, February 2021, The Company of Biologists

    Dr Sarah O'Keefe

  12. A potentially new broad-spectrum antiviral: a SARS-CoV-2 in vitro study

    Article • Journal of Cell Science, January 2021, The Company of Biologists

    Dr Sarah O'Keefe, Wei Shi

  13. Ring Expansion Leads to a More Potent Analogue of Ipomoeassin F

    Article • The Journal of Organic Chemistry, December 2020, American Chemical Society (ACS)

    Dr Sarah O'Keefe, Wei Shi

  14. A potentially new antibiotic?

    Article • Molecular Microbiology, September 2020, Wiley

    Dr Sarah O'Keefe

  15. Membrane translocation at the ER: with a little help from my friends

    Article • European Journal of Biochemistry, April 2020, Wiley

    Dr Sarah O'Keefe

  16. Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

    Article • Journal of the American Chemical Society, May 2019, American Chemical Society (ACS)

    Dr Sarah O'Keefe, Wei Shi, Belinda Hall

  17. Characterizing the selectivity of ER α-glucosidase inhibitors

    Article • Glycobiology, April 2019, Oxford University Press (OUP)

    Dr Sarah O'Keefe

  18. Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum

    Article • Cell Chemical Biology, April 2019, Elsevier

    Dr Sarah O'Keefe