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  1. Design and synthesis of some novel imidazole-thio-N-substituted-acetamide derivatives as anticancer agents, apoptotic inducers, radio-sensitizers, and EGFR inhibitors

    Article • Journal of Molecular Structure, October 2026, Elsevier

    Samiha El-Sebaey

  2. Quinoxaline-based scaffolds as dual VEGFR-2/EGFR kinase inhibitors and apoptotic inducers: Design, synthesis, anticancer evaluation, and in silico study

    Article • Bioorganic Chemistry, August 2026, Elsevier

    Samiha El-Sebaey

  3. Quinazolinone based broad-spectrum antiviral molecules: design, synthesis, in silico studies and biological evaluation

    Article • Molecular Diversity, June 2025, Springer Science + Business Media

    Samiha El-Sebaey

  4. Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation

    Article • European Journal of Medicinal Chemistry, February 2025, Elsevier

    Samiha El-Sebaey

  5. In vivo evaluation of novel synthetic pyrazolones as CDK9 inhibitors with enhanced pharmacokinetic properties

    Article • Future Medicinal Chemistry, November 2024, Taylor & Francis

    Samiha El-Sebaey

  6. Novel thioxoimidazolidinone derivatives as dual EGFR and CDK2 inhibitors: Design, synthesis, anticancer evaluation with in silico study

    Article • Journal of Molecular Structure, November 2023, Elsevier

    Samiha El-Sebaey

  7. Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies

    Article • Pharmaceuticals, September 2023, MDPI AG

    Samiha El-Sebaey

  8. Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, July 2023, Taylor & Francis

    Samiha El-Sebaey

  9. Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, April 2023, Taylor & Francis

    Samiha El-Sebaey

  10. Synthesis and Exploration of New Imidazo[4,5‐c]Pyrazoles as Potent α‐Amylase Inhibitors

    Article • ChemistrySelect, April 2023, Wiley

    Samiha El-Sebaey

  11. Synthesis of pyrido-annelated [1,2,4,5]tetrazines, [1,2,4]triazepine, and [1,2,4,5]tetrazepines for anticancer, DFT, and molecular docking studies

    Article • Scientific Reports, April 2023, Springer Science + Business Media

    Samiha El-Sebaey

  12. Design and synthesis of new series of chiral pyrimidine and purine analogs as COX-2 inhibitors: Anticancer screening, molecular modeling, and in silico studies

    Article • Journal of Molecular Structure, April 2023, Elsevier

    Samiha El-Sebaey

  13. Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, February 2023, Taylor & Francis

    Samiha El-Sebaey

  14. Design, synthesis and Molecular modeling study of certain EGFR inhibitors with a quinazolinone scaffold as anti-hepatocellular carcinoma and Radio-sensitizers

    Article • Bioorganic Chemistry, February 2023, Elsevier

    Samiha El-Sebaey

  15. Design, synthesis and molecular modeling study of certain quinazolinone derivatives targeting poly (ADP-ribose) polymerase 1 (PARP-1) enzyme as anti-breast cancer and radio-sensitizers

    Article • Journal of Molecular Structure, February 2023, Elsevier

    Samiha El-Sebaey

  16. New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies

    Article • PLOS One, January 2023, PLOS

    Samiha El-Sebaey, Wagdy Eldehna

  17. New Pyrimidine-5-Carbonitriles as COX-2 Inhibitors: Design, Synthesis, Anticancer Screening, Molecular Docking, and In Silico ADME Profile Studies

    Article • Molecules, November 2022, MDPI AG

    Samiha El-Sebaey

  18. Utility of 1,8-diaminonaphthalene in the synthesis of some novel heterocycles as potent anti-MRSA with dual DNA gyrase and topoisomerase IV inhibition

    Article • Egyptian Journal of Chemistry, December 2021, Egypts Presidential Specialized Council for Education and Scientific Research

    Samiha El-Sebaey

  19. Potential antiviral and anticancer effect of imidazoles and bridgehead imidazoles generated by HPV-Induced cervical carcinomas via reactivating the P53/ pRb pathway and inhibition of CA IX

    Article • Journal of Molecular Structure, April 2021, Elsevier

    Samiha El-Sebaey

  20. New benzothieno[2,3-c]pyridines as non-steroidal CYP17 inhibitors: design, synthesis, anticancer screening, apoptosis induction, and in silico ADME profile studies

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2021, Taylor & Francis

    Samiha El-Sebaey

  21. Recent Advances in 1,2,4‐Triazole Scaffolds as Antiviral Agents

    Article • ChemistrySelect, October 2020, Wiley

    Samiha El-Sebaey

  22. Derivatives and Fused Heterocyclic Compounds Derived from Thieno[2,3‐ b]pyridine: Recent Perspective

    Article • July 2020, Sciencedomain International

    Samiha El-Sebaey, Dr. Nadia Ali Ahmed Elkanzi

  23. Synthesis and antitumor evaluation of some new derivatives and fused heterocyclic compounds derived from thieno[2,3‐ b ]pyridine: Part 2

    Article • Journal of Heterocyclic Chemistry, November 2019, Wiley

    Samiha El-Sebaey

  24. Synthesis and antitumor evaluation of some new derivatives and fused heterocyclic compounds derived from thieno[2,3‐b]pyridine

    Article • Journal of Heterocyclic Chemistry, September 2019, Wiley

    Samiha El-Sebaey

  25. Utility of thieno[2,3-b] pyridine derivatives in the synthesis of some condensed heterocyclic compounds with expected biological activity

    Article • Universal Organic Chemistry, January 2013, Herbert Publications PVT LTD

    Samiha El-Sebaey