All Stories

  1. Monitoring Response to Combinatorial Immunotherapies by Tracking both T Cells and Natural Killer Cells In Vivo via ImmunoPET-Raman Multimodal Gold Nanostars

    Article • ACS Applied Materials & Interfaces, October 2025, American Chemical Society (ACS)

    saji uthaman

  2. LASIP: Light-Activated STING Immunotherapeutic Patch: A Multifunctional Microneedle Platform for Combinatorial Mild Hyperthermia with Immunotherapy in Breast Cancer

    Article • ACS Applied Materials & Interfaces, June 2025, American Chemical Society (ACS)

    saji uthaman

  3. Transformative therapy in acute microbial-induced colitis with inflammation triggered micelles and combination therapies

    Article • Nanoscale Horizons, January 2025, Royal Society of Chemistry

    saji uthaman

  4. Cisplatin-Induced Metabolic Responses Measured with Raman Spectroscopy in Cancer Cells, Spheroids, and Canine-Derived Organoids

    Article • ACS Applied Materials & Interfaces, September 2024, American Chemical Society (ACS)

    saji uthaman, Jonathan Paul Mochel

  5. Metabolic Response to Small Molecule Therapy in Colorectal Cancer Tracked with Raman Spectroscopy and Metabolomics

    Article • Angewandte Chemie, September 2024, Wiley

    saji uthaman

  6. Metabolic Response to Small Molecule Therapy in Colorectal Cancer Tracked with Raman Spectroscopy and Metabolomics

    Article • Angewandte Chemie, September 2024, Wiley

    saji uthaman

  7. Inhibiting the cGAS-STING Pathway in Ulcerative Colitis with Programmable Micelles

    Article • ACS Nano, April 2024, American Chemical Society (ACS)

    saji uthaman

  8. Reactive oxygen species driven prodrug-based nanoscale carriers for transformative therapies

    Article • Biomaterials Science, January 2024, Royal Society of Chemistry

    saji uthaman

  9. Monitoring Metabolic Changes in Response to Chemotherapies in Cancer with Raman Spectroscopy and Metabolomics

    Article • Analytical Chemistry, August 2023, American Chemical Society (ACS)

    saji uthaman

  10. First Trimester Prediction of Preterm Birth in Patient Plasma with Machine-Learning-Guided Raman Spectroscopy and Metabolomics

    Article • ACS Applied Materials & Interfaces, August 2023, American Chemical Society (ACS)

    saji uthaman

  11. A multi-stimuli responsive alginate nanogel for anticancer chemo-photodynamic therapy

    Article • Journal of Industrial and Engineering Chemistry, July 2023, Elsevier

    saji uthaman

  12. The Emerging Role of Raman Spectroscopy as an Omics Approach for Metabolic Profiling and Biomarker Detection toward Precision Medicine

    Article • Chemical Reviews, June 2023, American Chemical Society (ACS)

    saji uthaman

  13. Physicochemical Properties and Route of Systemic Delivery Control the In Vivo Dynamics and Breakdown of Radiolabeled Gold Nanostars

    Article • Small, March 2023, Wiley

    saji uthaman

  14. Effects of retinoid-loaded hyaluronic acid nanomicelles on vaginal epithelium in a murine menopause model

    Article • Investigative and Clinical Urology, January 2023, XMLink

    saji uthaman

  15. Light and immunostimulant mediated in situ re-education of tumor-associated macrophages using photosensitizer conjugated mannan nanoparticles for boosting immuno-photodynamic anti-metastasis therapy

    Article • Biomaterials Science, January 2023, Royal Society of Chemistry

    saji uthaman

  16. Tumor-targeting cell membrane-coated nanorings for magnetic-hyperthermia-induced tumor ablation

    Article • Biomaterials Science, January 2023, Royal Society of Chemistry

    saji uthaman

  17. Nanoplatforms for Anticancer Therapy Based on Reactive Oxygen Species

    Article • November 2022, Taylor & Francis

    saji uthaman

  18. Nanomaterials for Natural Killer Cell-Based Immunoimaging and Immunotherapies in Cancer

    Article • ACS Applied Materials & Interfaces, August 2022, American Chemical Society (ACS)

    saji uthaman

  19. Tumor intracellular microenvironment-responsive nanoparticles for magnetically targeted chemotherapy

    Article • Journal of Industrial and Engineering Chemistry, July 2022, Elsevier

    saji uthaman

  20. A Review of Different Vaccines and Strategies to Combat COVID-19

    Article • Vaccines, May 2022, MDPI AG

    saji uthaman

  21. Inflammation-sensing catalase-mimicking nanozymes alleviate acute kidney injury via reversing local oxidative stress

    Article • Journal of Nanobiotechnology, April 2022, Springer Science + Business Media

    saji uthaman

  22. Lipid–polymer hybrid nanoparticles as a smart drug delivery platform

    Article • January 2022, Elsevier

    saji uthaman

  23. Stimuli Responsive Nanoparticles for Anti-Cancer Therapy

    Article • January 2022, Frontiers

    saji uthaman

  24. Editorial: Stimuli-Responsive Nanoparticles for Anti-cancer Therapy

    Article • Frontiers in Bioengineering and Biotechnology, November 2021, Frontiers

    saji uthaman

  25. Heat‐Confined Tumor‐Docking Reversible Thermogel Potentiates Systemic Antitumor Immune Response During Near‐Infrared Photothermal Ablation in Triple‐Negative Breast Cancer

    Article • Advanced Healthcare Materials, September 2021, Wiley

    saji uthaman

  26. Degradable pH-responsive polymer prodrug micelles with aggregation-induced emission for cellular imaging and cancer therapy

    Article • Reactive and Functional Polymers, September 2021, Elsevier

    saji uthaman

  27. Two-tailed tadpole-shaped synthetic polymer polypeptide bioconjugate nanomicelles for enhanced chemo-photothermal therapy

    Article • Polymer, September 2021, Elsevier

    saji uthaman

  28. Drug-dye-apoptosis inducing micelles for enhancing host immunity against advanced metastatic breast cancer by the combination of low dose chemotherapy and photothermal therapy

    Article • Journal of Industrial and Engineering Chemistry, May 2021, Elsevier

    saji uthaman

  29. Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates lupus nephritis

    Article • Journal of Nanobiotechnology, April 2021, Springer Science + Business Media

    saji uthaman

  30. A combination of immunoadjuvant nanocomplexes and dendritic cell vaccines in the presence of immune checkpoint blockade for effective cancer immunotherapy

    Article • Cellular and Molecular Immunology, March 2021, Springer Science + Business Media

    saji uthaman

  31. Aggregation-induced emission-active hyperbranched polymer-based nanoparticles and their biological imaging applications

    Article • Dyes and Pigments, February 2021, Elsevier

    saji uthaman

  32. Tumor Microenvironment-Regulating Immunosenescence-Independent Nanostimulant Synergizing with Near-Infrared Light Irradiation for Antitumor Immunity

    Article • ACS Applied Materials & Interfaces, January 2021, American Chemical Society (ACS)

    saji uthaman

  33. External and Internal Stimuli-Responsive Metallic Nanotherapeutics for Enhanced Anticancer Therapy

    Article • Frontiers in Molecular Biosciences, January 2021, Frontiers

    saji uthaman

  34. Self-assembled heptamethine cyanine dye dimer as a novel theranostic drug delivery carrier for effective image-guided chemo-photothermal cancer therapy

    Article • Journal of Controlled Release, January 2021, Elsevier

    saji uthaman

  35. Vimentin Targeted Nano-gene Carrier for Treatment of Renal Diseases

    Article • Journal of Korean Medical Science, January 2021, Korean Academy of Medical Sciences (KAMJE)

    saji uthaman

  36. Corrigendum to “Glycol chitosan-based renal docking biopolymeric nanomicelles for site specific delivery of the immunosuppressant” [Carbohydr. Polym. 241 (2020) 116255]

    Article • Carbohydrate Polymers, December 2020, Elsevier

    saji uthaman

  37. Utilization of Polymer-Lipid Hybrid Nanoparticles for Targeted Anti-Cancer Therapy

    Article • Molecules, September 2020, MDPI AG

    saji uthaman

  38. Multistimuli-Responsive Polymeric Vesicles for Accelerated Drug Release in Chemo-photothermal Therapy

    Article • ACS Biomaterials Science & Engineering, August 2020, American Chemical Society (ACS)

    saji uthaman

  39. Glycol chitosan-based renal docking biopolymeric nanomicelles for site-specific delivery of the immunosuppressant

    Article • Carbohydrate Polymers, August 2020, Elsevier

    saji uthaman

  40. Photo‐ and pH‐Responsive Polycarbonate Block Copolymer Prodrug Nanomicelles for Controlled Release of Doxorubicin

    Article • Macromolecular Bioscience, June 2020, Wiley

    saji uthaman

  41. Self-Quenched Polysaccharide Nanoparticles with a Reactive Oxygen Species-Sensitive Cascade for Enhanced Photodynamic Therapy

    Article • ACS Applied Materials & Interfaces, June 2020, American Chemical Society (ACS)

    saji uthaman

  42. Bioactivatable reactive oxygen species-sensitive nanoparticulate system for chemo-photodynamic therapy

    Article • Acta Biomaterialia, May 2020, Elsevier

    saji uthaman

  43. Long circulating photoactivable nanomicelles with tumor localized activation and ROS triggered self-accelerating drug release for enhanced locoregional chemo-photodynamic therapy

    Article • Biomaterials, February 2020, Elsevier

    saji uthaman

  44. Recent Advances in Nanovaccines Using Biomimetic Immunomodulatory Materials

    Article • Pharmaceutics, October 2019, MDPI AG

    saji uthaman

  45. Multimodal Composite Iron Oxide Nanoparticles for Biomedical Applications

    Article • Tissue Engineering and Regenerative Medicine, October 2019, Springer Science + Business Media

    saji uthaman

  46. In vivo evaluation of cetuximab-conjugated poly(γ-glutamic acid)-docetaxel nanomedicines in EGFR-overexpressing gastric cancer xenografts [Corrigendum]

    Article • International Journal of Nanomedicine, June 2019, Dove Medical Press

    saji uthaman

  47. Design of an Amphiphilic Poly(aspartamide)-mediated Self-assembled Nanoconstruct for Long-Term Tumor Targeting and Bioimaging

    Article • Molecules, March 2019, MDPI AG

    saji uthaman

  48. “Navigate-dock-activate” anti-tumor strategy: Tumor micromilieu charge-switchable, hierarchically activated nanoplatform with ultrarapid tumor-tropic accumulation for trackable photothermal/chemotherapy

    Article • Theranostics, January 2019, Ivyspring International Publisher

    saji uthaman

  49. Biopolymeric In Situ Hydrogels for Tissue Engineering and Bioimaging Applications

    Article • Tissue Engineering and Regenerative Medicine, September 2018, Springer Science + Business Media

    saji uthaman

  50. Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics

    Article • Polymers, September 2018, MDPI AG

    saji uthaman

  51. Injectable Biomaterials in Plastic and Reconstructive Surgery: A Review of the Current Status

    Article • Tissue Engineering and Regenerative Medicine, September 2018, Springer Science + Business Media

    saji uthaman

  52. Tumor microenvironment-responsive nanoparticles for cancer theragnostic applications

    Article • Biomaterials Research, August 2018, Springer Science + Business Media

    saji uthaman

  53. In-direct localized surface plasmon resonance (LSPR)-based nanosensors for highly sensitive and rapid detection of cortisol

    Article • Sensors and Actuators B Chemical, August 2018, Elsevier

    saji uthaman

  54. Nanoparticle-Based Phototriggered Cancer Immunotherapy and Its Domino Effect in the Tumor Microenvironment

    Article • Biomacromolecules, April 2018, American Chemical Society (ACS)

    saji uthaman

  55. A Lipophilic IR-780 Dye-Encapsulated Zwitterionic Polymer-Lipid Micellar Nanoparticle for Enhanced Photothermal Therapy and NIR-Based Fluorescence Imaging in a Cervical Tumor Mouse Model

    Article • International Journal of Molecular Sciences, April 2018, MDPI AG

    saji uthaman

  56. Synthesis and characterization of bioreducible cationic biarm polymer for efficient gene delivery

    Article • International Journal of Biological Macromolecules, April 2018, Elsevier

    saji uthaman

  57. Dual-stimuli-responsive albumin-polyplex nanoassembly for spatially controlled gene release in metastatic breast cancer

    Article • Journal of Controlled Release, April 2018, Elsevier

    saji uthaman

  58. IR 780-loaded hyaluronic acid micelles for enhanced tumor-targeted photothermal therapy

    Article • Carbohydrate Polymers, February 2018, Elsevier

    saji uthaman

  59. Green synthesis of bioactive polysaccharide-capped gold nanoparticles for lymph node CT imaging

    Article • Carbohydrate Polymers, February 2018, Elsevier

    saji uthaman

  60. Cell Membrane Coated Nanoparticles: An Emerging Biomimetic Nanoplatform for Targeted Bioimaging and Therapy

    Article • January 2018, Springer Science + Business Media

    saji uthaman

  61. Injectable Nanogels in Drug Delivery

    Article • November 2017, Royal Society of Chemistry

    saji uthaman

  62. Injectable hydrogels for delivering biotherapeutic molecules

    Article • International Journal of Biological Macromolecules, November 2017, Elsevier

    saji uthaman

  63. Glutathione and endosomal pH-responsive hybrid vesicles fabricated by zwitterionic polymer block poly( l -aspartic acid) as a smart anticancer delivery platform

    Article • Reactive and Functional Polymers, October 2017, Elsevier

    saji uthaman

  64. In vivo evaluation of cetuximab-conjugated poly(γ-glutamic acid)-docetaxel nanomedicines in EGFR-overexpressing gastric cancer xenografts

    Article • International Journal of Nanomedicine, September 2017, Dove Medical Press

    saji uthaman

  65. Trigger-Responsive Gene Transporters for Anticancer Therapy

    Article • Nanomaterials, May 2017, MDPI AG

    saji uthaman

  66. Stimuli-Regulated Smart Polymeric Systems for Gene Therapy

    Article • Polymers, April 2017, MDPI AG

    saji uthaman

  67. Biomimetic pH/redox dual stimuli-responsive zwitterionic polymer block poly( L -histidine) micelles for intracellular delivery of doxorubicin into tumor cells

    Article • Journal of Polymer Science Part A Polymer Chemistry, April 2017, Wiley

    Professor Il Kim, saji uthaman

  68. pH/redox dual stimuli-responsive sheddable nanodaisies for efficient intracellular tumour-triggered drug delivery

    Article • Journal of Materials Chemistry B, January 2017, Royal Society of Chemistry

    saji uthaman

  69. Bioreducible branched poly(modified nona-arginine) cell-penetrating peptide as a novel gene delivery platform

    Article • Journal of Controlled Release, January 2017, Elsevier

    saji uthaman

  70. Multifunctional Inorganic Nanoparticles: Recent Progress in Thermal Therapy and Imaging

    Article • Nanomaterials, April 2016, MDPI AG

    saji uthaman

  71. Tumor homing indocyanine green encapsulated micelles for near infrared and photoacoustic imaging of tumors

    Article • Journal of Biomedical Materials Research Part B Applied Biomaterials, January 2016, Wiley

    saji uthaman

  72. Fabrication and development of magnetic particles for gene therapy

    Article • January 2016, Elsevier

    saji uthaman

  73. Novel Fabrication of MicroRNA Nanoparticle-Coated Coronary Stent for Prevention of Post-Angioplasty Restenosis

    Article • Korean Circulation Journal, January 2016, The Korean Society of Cardiology (KAMJE)

    saji uthaman

  74. Preparation of EngineeredSalmonella Typhimurium-Driven Hyaluronic-Acid-Based Microbeads with Both Chemotactic and Biological Targeting Towards Breast Cancer Cells for Enhanced Anticancer Therapy

    Article • Advanced Healthcare Materials, November 2015, Wiley

    saji uthaman

  75. Di-Sulfide Linked Polyethylenimine Coated Gold Nanoparticles as a Non-Viral Gene Delivery Agent in NIH-3T3 Mouse Embryonic Fibroblast

    Article • Journal of Nanoscience and Nanotechnology, October 2015, American Scientific Publishers

    saji uthaman

  76. Poly(PEGA)-b-poly(l-lysine)-b-poly(l-histidine) Hybrid Vesicles for Tumoral pH-Triggered Intracellular Delivery of Doxorubicin Hydrochloride

    Article • ACS Applied Materials & Interfaces, September 2015, American Chemical Society (ACS)

    saji uthaman

  77. Biodegradable poly(ethylene glycol) methyl ether acrylate- b -poly( l -lysine)- b -poly( l -histidine) triblock copolypeptides for non-viral gene delivery

    Article • Journal of Controlled Release, September 2015, Elsevier

    saji uthaman

  78. Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer

    Article • OncoImmunology, August 2015, Taylor & Francis

    saji uthaman

  79. Biomedical Applications of Magnetically Functionalized Organic/Inorganic Hybrid Nanofibers

    Article • International Journal of Molecular Sciences, June 2015, MDPI AG

    saji uthaman

  80. Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    saji uthaman

  81. Effect of chitosan coating on a bacteria-based alginate microrobot

    Article • Biotechnology and Bioengineering, December 2014, Wiley

    saji uthaman

  82. Poly(2-Hydroxyethyl Methacrylate)-b-Poly(L-Lysine) Cationic Hybrid Materials for Non-Viral Gene Delivery in NIH 3T3 Mouse Embryonic Fibroblasts

    Article • Macromolecular Bioscience, May 2014, Wiley

    saji uthaman

  83. Carbohydrate-Based Nanogels as Drug and Gene Delivery Systems

    Article • Journal of Nanoscience and Nanotechnology, January 2014, American Scientific Publishers

    saji uthaman

  84. Design and development of biodegradable bacterial-based microrobot for anti-tumour therapy

    Article • October 2013, Institute of Electrical & Electronics Engineers (IEEE)

    saji uthaman

  85. Enhanced Delivery System of Flutamide Loaded Chitosan-Dextran Sulphate Nanoparticles for Prostate Cancer

    Article • Journal of Biomedical Nanotechnology, March 2013, American Scientific Publishers

    saji uthaman

  86. Therapeutic Properties of Boswellic Acid Nanoparticles in Prostate Tumor–Bearing BALB/c Mice Model

    Article • Journal of Nanopharmaceutics and Drug Delivery, March 2013, American Scientific Publishers

    saji uthaman