All Stories

  1. Design, synthesis and catalytic application of water-soluble 1,1′-bis(diphenylphosphino)ferrocene ligands
  2. Recent Advances in Pd‐Catalyzed Suzuki‐Miyaura Cross‐Coupling Reactions with Triflates or Nonaflates
  3. Constraining and Modifying Peptides Using Pd‐Mediated Cysteine Allylation
  4. Constraining and Modifying Peptides Using Pd‐Mediated Cysteine Allylation
  5. Reaction intensification for biocatalytic production of polyphenolic natural product di‐ C ‐β‐glucosides
  6. Activity‐Based Protein Profiling of Oxidases and Reductases
  7. Enterotoxin tilimycin from gut-resident Klebsiella promotes mutational evolution and antibiotic resistance in mice
  8. Design and synthesis of efficient fluororethylene-peptidomimetic inhibitors of dipeptidyl peptidase III (DPP3)
  9. Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes
  10. A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 3: Iodophenyltriflate Core Fragments Featuring Side Chains of Proteinogenic Amino Acids
  11. A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 4: Core Fragments with Two Halide Leaving Groups Featuring Side Chains of Proteinogenic Amino Acids
  12. A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 5: A Complete Set of Pyridine Boronic Acid Pinacol Esters Featuring Side Chains of Proteinogenic Amino Acids
  13. Total synthesis of the isoquinolinium metabolite ETM-204 of Trabectidin
  14. Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket
  15. Efficient Entropy‐Driven Inhibition of Dipeptidyl Peptidase III by Hydroxyethylene Transition‐State Peptidomimetics
  16. Pharmacological inhibition of adipose tissue adipose triglyceride lipase by Atglistatin prevents catecholamine-induced myocardial damage
  17. Organische Chemie
  18. Simultaneous quantification of enterotoxins tilimycin and tilivalline in biological matrices using HPLC high resolution ESMS2 based on isotopically 15N-labeled internal standards
  19. Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation
  20. Synthesis of Hydrophilic Phosphorus Ligands and Their Application in Aqueous‐Phase Metal‐Catalyzed Reactions
  21. Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven hepatic lipogenesis
  22. Activity‐Based Protein Profiling (ABPP) of Oxidoreductases
  23. Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)
  24. Stereoselective synthesis of chiral thiol-containing 1,2-aminoalcohols via SmI2-mediated coupling
  25. Synthesis of a Bcl9 Alpha-Helix Mimetic for Inhibition of PPIs by a Combination of Electrooxidative Phenol Coupling and Pd-Catalyzed Cross Coupling
  26. Organische Chemie
  27. Pd/BIPHEPHOS is an Efficient Catalyst for the Pd‐Catalyzed S ‐Allylation of Thiols with High n ‐Selectivity
  28. Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine
  29. Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans
  30. Trendbericht Organische Chemie
  31. Synthesis of 2-Pyrrolidinones by Palladium-Catalyzed [3+2] Cycloaddition of Isocyanates
  32. Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities
  33. Selective Formation of 4,4′-Biphenols by Anodic Dehydrogenative Cross- and Homo-Coupling Reaction
  34. Aliphatic hydroxylation and epoxidation of capsaicin by cytochrome P450 CYP505X
  35. Atglistatin ameliorates functional decline in heart failure via adipocyte-specific inhibition of adipose triglyceride lipase
  36. Application of Threonine Aldolases for the Asymmetric Synthesis of α-Quaternary α-Amino Acids
  37. The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition
  38. Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases
  39. Asymmetrische reduktive Carbocyclisierung durch modifizierte En-Reduktasen
  40. The highlights in organic chemistry of 2017
  41. C H and C C bond insertion reactions of diazo compounds into aldehydes
  42. Synthesis of novel ligands targeting phenazine biosynthesis proteins as a strategy for antibiotic intervention
  43. Recent developments in the isolation, biological function, biosynthesis, and synthesis of phenazine natural products
  44. Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline
  45. Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF
  46. Erratum: Corrigendum: Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
  47. Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
  48. Highlights in organic chemistry 2016
  49. Synthesis of α,β-unsaturated aldehydes as potential substrates for bacterial luciferases
  50. Additive-Free Pd-Catalyzed α-Allylation of Imine-Containing Heterocycles
  51. Sequential and iterative Pd-catalyzed cross-coupling reactions in organic synthesis
  52. Characterization of the monolignol oxidoreductase AtBBE-like protein 15 L182V for biocatalytic applications
  53. Comparative Activity-Based Flavin-Dependent Oxidase Profiling
  54. Enzymatic hydrolysis of poly(ethylene furanoate)
  55. ChemInform Abstract: A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines.
  56. Target identification of small molecule drugs and chemical probes
  57. Target identification of covalently binding drugs by activity-based protein profiling (ABPP)
  58. Tracking Protein S-Fatty Acylation with Proteomics
  59. Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p
  60. Future Directions of Modern Organic Synthesis
  61. Organic Chemistry 2015
  62. A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines
  63. Aus zwei mach eins: die Biosynthese der Phenazine
  64. ChemInform Abstract: Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism
  65. Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism
  66. ChemInform Abstract: A Rapid and Efficient One-Pot Method for the Reduction of N-Protected α-Amino Acids to Chiral α-Amino Aldehydes Using CDI/DIBAL-H.
  67. ChemInform Abstract: A Robust and Simple Protocol for the Synthesis of Arylfluorophosphonates.
  68. Improved and scalable synthesis of building blocks for the modular synthesis of teraryl-based alpha-helix mimetics
  69. Diversity-Oriented Synthesis of a Library of Star-Shaped 2H-Imidazolines
  70. α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate
  71. A robust and simple protocol for the synthesis of arylfluorophosphonates
  72. Reductions of Carboxylic Acids and Derivatives
  73. Expanding the threonine aldolase toolbox for the asymmetric synthesis of tertiary α-amino acids
  74. Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells
  75. Biocatalyzed approach for the surface functionalization of poly(L-lactic acid) films using hydrolytic enzymes
  76. Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)
  77. Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling
  78. Weighing the Proteasome for Covalent Modifications
  79. ChemInform Abstract: Recent Advances and Applications of Reductive Desulfurization in Organic Synthesis
  80. A rapid and efficient one-pot method for the reduction of N-protected α-amino acids to chiral α-amino aldehydes using CDI/DIBAL-H
  81. Recent advances and applications of reductive desulfurization in organic synthesis
  82. Biosynthese der Phenazine
  83. Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis
  84. ChemInform Abstract: The Development of a Modular Synthesis of Teraryl-Based α-Helix Mimetics as Potential Inhibitors of Protein-Protein Interactions
  85. Exploring the new threonine aldolases with broad donor specificity
  86. Stereochemistry and Mechanism of Enzymatic and Non-Enzymatic Hydrolysis of Benzylicsec-Sulfate Esters
  87. Enzymes in Organic Synthesis
  88. The Development of a Modular Synthesis of Teraryl-Based α-Helix Mimetics as Potential Inhibitors of Protein–Protein Interactions
  89. Organische Chemie 2013
  90. More than just a Halogenase: Modification of Fatty Acyl Moieties by a Trifunctional Metal Enzyme
  91. Towards the synthesis of glycosylated dihydrochalcone natural products using glycosyltransferase-catalysed cascade reactions
  92. Investigation of one-enzyme systems in the ω-transaminase-catalyzed synthesis of chiral amines
  93. Development of small-molecule inhibitors targeting adipose triglyceride lipase
  94. Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase
  95. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators
  96. Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ruthenium-Catalyzed Synthesis of Peptide Enol EstersviaAlkyne-Addition and Subsequent Conversion Using Alcalase-Cross-Linked Enzyme Aggregates
  97. ChemInform Abstract: An Efficient Labeling Strategy of Drug Like Molecules with Functionalized Alkyl Linkers Using CH-Activation.
  98. A Modular Synthesis of Teraryl-Based α-Helix Mimetics, Part 1: Synthesis of Core Fragments with Two Electronically Differentiated Leaving Groups
  99. Investigation of the origin and synthetic application of the pseudodilution effect for Pd-catalyzed macrocyclisations in concentrated solutions with immobilized catalysts
  100. A Modular Synthesis of Teraryl-Based α-Helix Mimetics, Part 2: Synthesis of 5-Pyridine Boronic Acid Pinacol Ester Building Blocks with Amino Acid Side Chains in 3-Position
  101. Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors
  102. Aktivitätsbasierte Sondenmoleküle zur Untersuchung der Aktivität Flavin-abhängiger Oxidasen und zum Zielprotein-Profiling von Monoaminooxidase-Inhibitoren
  103. An efficient labeling strategy of drug like molecules with functionalized alkyl linkers using CH-activation
  104. ChemInform Abstract: The Witkop-Winterfeldt Oxidation Converts Tetrahydropyridoindoles into Pyrroloquinolones and Cinnolines by an Unprecedented Scaffold Rearrangement.
  105. ChemInform Abstract: A Simple Synthesis of Functionalized 3-Methyl-1-pyridinyl-1H-imidazolium Salts as Bidentate N-Heterocyclic-carbene Precursors and Their Application in Ir-Catalyzed Arene Borylation.
  106. The Witkop–Winterfeldt oxidation converts tetrahydropyridoindoles into pyrroloquinolones and cinnolines by an unprecedented scaffold rearrangement
  107. Activity-Based Protein Profiling for Natural Product Target Discovery
  108. ChemInform Abstract: Combinatorial Chemistry and the Synthesis of Compound Libraries
  109. A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation
  110. ChemInform Abstract: Suzuki and Heck Reactions Catalyzed by Preformed Palladium Clusters and Palladium/Nickel Bimetallic Clusters.
  111. ChemInform Abstract: From Protein Domains to Drug Candidates - Natural Products as Guiding Principles in the Design and Synthesis of Compound Libraries.
  112. ChemInform Abstract: Solid-Phase Synthesis of Biomolecules
  113. Organische Chemie 2009
  114. Preparation of Biomolecule Microstructures and Microarrays by Thiol-ene Photoimmobilization
  115. ChemInform Abstract: Of Two Make One: The Biosynthesis of Phenazines
  116. The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously
  117. Gleichzeitige Bindung beider Enantiomere eines racemischen Wirkstoffs durch das aktive Zentrum eines Enzyms
  118. Combinatorial Chemistry and the Synthesis of Compound Libraries
  119. Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with (S)-5-bromo-2-(piperidin-3-ylamino)benzoic acid
  120. Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with 5-bromo-2-((1S,3R)-3-carboxycyclohexylamino)benzoic acid
  121. Crystal Structure of PhzA/B from Burkholderia cepacia R18194 cocrystallized with 2 mM racemic 5-bromo-2-(piperidin-3-ylamino)benzoic acid
  122. Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with (R)-5-bromo-2-(piperidin-3-ylamino)benzoic acid
  123. Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in simultaneous complex with racemic 5-bromo-2-(piperidin-3-ylamino)benzoic acid
  124. ChemInform Abstract: An Environmentally Benign Electrochemical Process for the Reduction of Carboxylic Acid Hydrazides to Amides.
  125. Of Two Make One: The Biosynthesis of Phenazines
  126. Polystyrene Sulfonyl Chloride: A Highly Orthogonal Linker Resin for the Synthesis of Nitrogen-Containing Heterocycles
  127. Polystyrolsulfonylchlorid - ein hochorthogonales Linkerharz für die Synthese von Stickstoffheterocyclen
  128. The Power of Functional Resins in Organic Synthesis.Herausgegeben von Judit Tulla-Puche und Fernando Albericio.
  129. The Power of Functional Resins in Organic Synthesis.Edited by Judit Tulla-Puche and Fernando Albericio.
  130. Classics in Stereoselective Synthesis
  131. An Environmentally Benign Electrochemical Process for the Reduction of Carboxylic Acid Hydrazides to Amides
  132. Organische Chemie 2008
  133. Crystal structure of phenazine biosynthesis protein PhzA/B from Burkholderia cepacia R18194, apo form
  134. Crystal structure of phenazine biosynthesis protein PhzA/B from Burkholderia cepacia R18194, complex with 2-(cyclohexylamino)benzoic acid
  135. Crystal structure of PhzA/B from Burkholderia cepacia R18194 crystallized in C2221
  136. ChemInform Abstract: Combinatorial Solid-Phase Natural Product Chemistry
  137. PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis
  138. Photochemical Surface Patterning by the Thiol-Ene Reaction
  139. Photochemical Surface Patterning by the Thiol-Ene Reaction
  140. Solid-Phase Synthesis of Biomolecules
  141. The Synthetic Organic Chemist’s Companion
  142. ChemInform Abstract: The Witkop-Winterfeldt Oxidation of Indoles
  143. The Way of Synthesis: Evolution of Design and Methods for Natural Products
  144. Electrons as a Reagent in Solid-Phase Organic Synthesis
  145. A Microarray Strategy for Mapping the Substrate Specificity of Protein Tyrosine Phosphatase
  146. Eine Mikroarray-Strategie zur Untersuchung der Substratspezifitäten von Protein-Tyrosin-Phosphatasen
  147. Organic Reactions in Water: Principles, Strategies and Applications
  148. Electrons as a Reagent in Solid-Phase Organic Synthesis (Eur. J. Org. Chem. 26/2007)
  149. Electrons as a Reagent in Solid‐Phase Organic Synthesis
  150. The Investigation of Organic Reactions and their Mechanisms
  151. Organische Chemie 2006
  152. Domino Reactions in Organic Synthesis
  153. The Witkop-Winterfeldt-Oxidation of Indoles
  154. Combinatorial Chemistry - From Theory to Application (Methods and Principles in Medicinal Chemistry, Vol. 26)
  155. A generic building block for C- and N-terminal protein-labeling and protein-immobilization
  156. Electroorganic Reductions Syntheses
  157. High-Throughput Screening in Chemical Catalysis - Technologies, Strategies and Applications
  158. Homogeneous Polymer-Supported Synthesis of N-Substituted Pyrroles
  159. Organische Chemie 2005
  160. Site-Selective Protein Immobilization by Staudinger Ligation
  161. Site-Selective Protein Immobilization by Staudinger Ligation
  162. Electrolysis as an Efficient Key Step in the Homogeneous Polymer-Supported Synthesis of N-Substituted Pyrroles
  163. Evaluation of Enzyme Inhibitors in Drug Discovery. Von Robert A. Copeland.
  164. Evaluation of Enzyme Inhibitors in Drug Discovery. By Robert A. Copeland.
  165. Solid-Supported Reagents and Catalysts for the Preparation of Large Ring Compounds
  166. Nutzen und Gefahren der Biotechnologie: Liebling, Du hast die Katze geklont. Von Reinhard Renneberg, Manfred Bofinger, Jens Reich. Wiley-VCH, Weinheim 2004.260 Seiten, geb., 24,90 Euro. ISBN 3-527-31075-4
  167. Electroorganic Synthesis of 2,5-Dialkoxydihydrofurans and Pyridazines on Solid Phase Using Polymer Beads as Supports
  168. Solid-supported reagents and catalysts for the preparation of large ring compounds
  169. Preface
  170. The Staudinger Ligation — A Gift to Chemical Biology
  171. Polymer-Supported Synthesis of Non-Oligomeric Natural Products
  172. Molecular Biology in Medicinal Chemistry. Band 21 der Reihe Methods and Principles in Medicinal Chemistry. Herausgegeben von Theodor Dingermann, Dieter Steinhilber und Gerd Folkers.
  173. Molecular Biology in Medicinal Chemistry. (Series: Methods and Principles in Medicinal Chemistry, Vol. 21.) Edited by Theodor Dingermann, Dieter Steinhilber and Gerd Folkers.
  174. The Staudinger Ligation—A Gift to Chemical Biology
  175. Die Staudinger-Ligation– ein Geschenk für die Chemische Biologie
  176. Der Gipfel der Stereochemie: Bürgenstock 2004
  177. The Peak of Stereochemistry: Bürgenstock 2004
  178. Electroorganic Synthesis on the Solid Phase using Polymer Beads as Supports
  179. Elektroorganische Synthese an der festen Phase mit Polymerkügelchen als Trägermaterial
  180. An efficient and inexpensive scavenger resin for Grubbs’ catalyst
  181. Small Molecule Arrays
  182. Staudinger Ligation: A New Immobilization Strategy for the Preparation of Small-Molecule Arrays
  183. Staudinger-Ligation: eine Immobilisierungsstrategie zur Herstellung von Wirkstoff-Arrays
  184. Azide-Alkyne Coupling: A Powerful Reaction for Bioconjugate Chemistry
  185. An Easily Accessible Resin-Supported Palladium Catalyst for Sonogashira Coupling.
  186. Die chemische Genetik entdeckt das (Zebra-)Fischen
  187. Chemical Genetics Goes (Zebra) Fishing
  188. Protein Structure Similarity as Guiding Principle for Combinatorial Library Design
  189. Polymer‐Supported Synthesis of Non‐Oligomeric Natural Products
  190. An Easily Accessible Resin-SupportedPalladium Catalyst for Sonogashira Coupling
  191. Natural Product Guided Compound Library Development
  192. Book Review: Handbook of Combinatorial Chemistry. Vols. 1+2. By Kyriacos C. Nicolaou, R. Hanko and W. Hartwig
  193. Buchbesprechung: Handbook of Combinatorial Chemistry. Band 1+2. Herausgegeben von Kyriacos C. Nicolaou, R. Hanko und W. Hartwig
  194. From Protein Domains to Drug Candidates—Natural Products as Guiding Principles in the Design and Synthesis of Compound Libraries
  195. Von Proteindomänen zu Wirkstoffkandidaten – Naturstoffe als Leitstrukturen für das Design und die Synthese von Substanzbibliotheken
  196. Nachwuchswissenschaftler-Symposium Bioorganische Chemie
  197. Web Site: Lehrbücher mit Websites
  198. Web Site: Lehrbücher mit Websites
  199. Web Site: Companion Sites for Textbooks
  200. Web Site: Companion Sites for Textbooks
  201. Essentials of Biological Chemistry. Von Lorraine Buckberry und Paul Teesdale
  202. Essentials of Biological Chemistry. By Lorraine Buckberry and Paul Teesdale
  203. Size-Selective Electrochemical Preparation of Surfactant-Stabilized Pd-, Ni- and Pt/Pd Colloids
  204. Organische Chemie der Carbonylverbindungen: Modern Carbonyl Chemistry. Hrsg. von Junzo Otera. Wiley-VCH, Weinheim, 2000. 613 5., geb., 298,- DM. ISBN 3-527-29871-1
  205. Cooperative Asymmetric Catalysis with Dendrimeric [Co(salen)] Complexes
  206. Cooperative Asymmetric Catalysis with Dendrimeric [Co(salen)] Complexes
  207. POLYMER CHEMISTRY:Nickel Comes Full Cycle
  208. Nanostructured nickel-clusters as catalysts in [3+2]cycloaddition reactions
  209. Suzuki and Heck reactions catalyzed by preformed palladium clusters and bimetallic clusters
  210. A New Strategy in Heterogeneous Catalysis: The Design of Cortex Catalysts
  211. Eine neue Strategie in der heterogenen Katalyse: das Design von Cortex-Katalysatoren
  212. Polymer-Supported Synthesis of Non-Oligomeric Natural Products
  213. Reverse Chemical Genetics– An Important Strategy for the Study of Protein Function in Chemical Biology and Drug Discovery
  214. Combinatorial Solid-Phase Natural Product Chemistry