All Stories

  1. Identification of Potential Prophylactic Medical Countermeasures Against Acute Radiation Syndrome (ARS)

    Article • International Journal of Molecular Sciences, April 2025, MDPI AG

    Dr Robert Powers

  2. Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis

    Article • Journal of Biological Chemistry, January 2025, Elsevier

    Dr Robert Powers

  3. A reproducibility crisis for clinical metabolomics studies

    Article • TrAC Trends in Analytical Chemistry, November 2024, Elsevier

    Dr Robert Powers

  4. Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Applications for Metabolomics

    Article • Biomedicines, August 2024, MDPI AG

    Dr Robert Powers

  5. Simulated LC–MS Data Set for Assessing the Metabolomics Data Processing Pipeline Implemented into MVAPACK

    Article • Analytical Chemistry, July 2024, American Chemical Society (ACS)

    Dr Robert Powers

  6. Potential Metabolite Biomarkers of Multiple Sclerosis from Multiple Biofluids

    Article • ACS Chemical Neuroscience, February 2024, American Chemical Society (ACS)

    Dr Robert Powers

  7. Best practices in NMR metabolomics: Current state

    Article • TrAC Trends in Analytical Chemistry, February 2024, Elsevier

    Dr Robert Powers

  8. Evaluating Protocols for Reproducible Targeted Metabolomics by NMR

    Article • The Analyst, January 2024, Royal Society of Chemistry

    Dr Benjamin Mullish, Dr Robert Powers

  9. Frontiers in NMR metabolomics

    Article • Magnetic Resonance in Chemistry, November 2023, Wiley

    Dr Robert Powers

  10. Histidine Enhances the Anticancer Effect of Gemcitabine against Pancreatic Cancer via Disruption of Amino Acid Homeostasis and Oxidant—Antioxidant Balance

    Article • Cancers, May 2023, MDPI AG

    Dr Robert Powers

  11. Multiplatform untargeted metabolomics

    Article • Magnetic Resonance in Chemistry, April 2023, Wiley

    Dr Robert Powers

  12. The reversible low‐temperature instability of human DJ‐1 oxidative states

    Article • Biopolymers, March 2023, Wiley

    Dr Robert Powers

  13. Multiomics Approach Captures Hepatic Metabolic Network Altered by Chronic Ethanol Administration

    Article • Biology, December 2022, MDPI AG

    Dr Robert Powers

  14. Chemical shift variations in common metabolites

    Article • Journal of Magnetic Resonance, December 2022, Elsevier

    Dr Robert Powers

  15. Leveraging the HMBC to Facilitate Metabolite Identification

    Article • Analytical Chemistry, November 2022, American Chemical Society (ACS)

    Dr Robert Powers

  16. Multi-omics Investigation into the Mechanism of Action of an Anti-tubercular Fatty Acid Analogue

    Article • Journal of the American Chemical Society, November 2022, American Chemical Society (ACS)

    Dr Robert Powers

  17. Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies

    Article • Biomolecules, September 2022, MDPI AG

    Dr Robert Powers

  18. Meta-Analysis Reveals Both the Promises and the Challenges of Clinical Metabolomics

    Article • Cancers, August 2022, MDPI AG

    Dr Robert Powers

  19. NMR and Metabolomics—A Roadmap for the Future

    Article • Metabolites, July 2022, MDPI AG

    Dr Robert Powers

  20. Human Serum Alters the Metabolism and Antibiotic Susceptibility of Staphylococcus aureus

    Article • Journal of Proteome Research, May 2022, American Chemical Society (ACS)

    Dr Robert Powers

  21. Gadolinium-Based Paramagnetic Relaxation Enhancement Agent Enhances Sensitivity for NUS Multidimensional NMR-Based Metabolomics

    Article • Molecules, August 2021, MDPI AG

    Dr Robert Powers

  22. Closing the gap between in vivo and in vitro omics: using QA/QC to strengthen ex vivo NMR metabolomics

    Article • NMR in Biomedicine, August 2021, Wiley

    Dr Robert Powers

  23. DNAJA1 Dysregulates Metabolism Promoting an Antiapoptotic Phenotype in Pancreatic Ductal Adenocarcinoma

    Article • Journal of Proteome Research, July 2021, American Chemical Society (ACS)

    Dr Robert Powers

  24. Quantitative NMR-Based Biomedical Metabolomics: Current Status and Applications

    Article • Molecules, November 2020, MDPI AG

    Dr Robert Powers

  25. DNAJA1 dysregulates metabolism promoting an anti-apoptotic phenotype in pancreatic ductal adenocarcinoma

    Article • September 2020, Research Square

    Dr Robert Powers

  26. Phosphorus NMR and Its Application to Metabolomics

    Article • Analytical Chemistry, June 2020, American Chemical Society (ACS)

    Dr Robert Powers

  27. Evaluation of Non-Uniform Sampling 2D 1H–13C HSQC Spectra for Semi-Quantitative Metabolomics

    Article • Metabolites, May 2020, MDPI AG

    Dr Robert Powers

  28. Evaluation of Multivariate Classification Models for Analyzing NMR Metabolomics Data

    Article • Journal of Proteome Research, August 2019, American Chemical Society (ACS)

    Dr Robert Powers

  29. Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity

    Article • Peptides, July 2019, Elsevier

    Dr Robert Powers

  30. Novel Amphiphilic Cyclobutene and Cyclobutane cis-C18 Fatty Acid Derivatives Inhibit Mycobacterium avium subsp. paratuberculosis Growth

    Article • Veterinary Sciences, May 2019, MDPI AG

    Dr Robert Powers

  31. O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

    Article • Immunity, April 2019, Elsevier

    Dr Robert Powers

  32. Functional Evolution of Proteins

    Article • Proteins Structure Function and Bioinformatics, February 2019, Wiley

    Dr Robert Powers

  33. Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection

    Article • PLoS Pathogens, January 2019, PLOS

    Dr Robert Powers, Paul Fey

  34. Insights into gemcitabine resistance and the potential for therapeutic monitoring

    Article • Metabolomics, November 2018, Springer Science + Business Media

    Dr Robert Powers

  35. Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation

    Article • Journal of Proteome Research, October 2018, American Chemical Society (ACS)

    Dr Robert Powers

  36. Comparing normalization methods and the impact of noise

    Article • Metabolomics, August 2018, Springer Science + Business Media

    Dr Robert Powers

  37. Expanding the Coverage of the Metabolome with Nitrogen-Based NMR

    Article • Analytical Chemistry, March 2018, American Chemical Society (ACS)

    Dr Robert Powers

  38. 15 N CEST data and traditional model-free analysis capture fast internal dynamics of DJ-1

    Article • Analytical Biochemistry, February 2018, Elsevier

    Dr Robert Powers

  39. Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility

    Article • Antimicrobial Agents and Chemotherapy, November 2017, ASM Journals

    Dr Robert Powers, Dr Greg A Somerville

  40. Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells

    Article • Journal of Proteome Research, August 2017, American Chemical Society (ACS)

    Dr Robert Powers

  41. Nanoformulated Copper/Zinc Superoxide Dismutase Exerts Differential Effects on Glucose versus Lipid Homeostasis Depending on the Diet Composition Possibly via Altered AMPK Signaling

    Article • Translational Research, August 2017, Elsevier

    Dr Robert Powers

  42. New frontiers in metabolomics: from measurement to insight

    Article • F1000Research, July 2017, Faculty of 1000, Ltd.

    Dr Robert Powers, Eli Riekeberg

  43. Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s Disease

    Article • Metabolites, May 2017, MDPI AG

    Dr Robert Powers

  44. Assessment of Metabolic Changes in Mycobacterium smegmatis Wild-Type and alr Mutant Strains: Evidence of a New Pathway of d-Alanine Biosynthesis

    Article • Journal of Proteome Research, February 2017, American Chemical Society (ACS)

    Dr Robert Powers

  45. Amino Acid Catabolism in Staphylococcus aureus and the Function of Carbon Catabolite Repression

    Article • mBio, February 2017, ASM Journals

    Dr Robert Powers, Paul Fey

  46. Identification of a Ligand-Binding Site on the Staphylococcus aureus DnaG Primase C-Terminal Domain

    Article • Biochemistry, February 2017, American Chemical Society (ACS)

    Dr Robert Powers

  47. PCA as a Practical Indicator of OPLS-DA Model Reliability

    Article • Current Metabolomics, June 2016, Bentham Science Publishers

    Dr Robert Powers

  48. Deterministic multidimensional nonuniform gap sampling

    Article • Journal of Magnetic Resonance, December 2015, Elsevier

    Dr Robert Powers

  49. Staphylococcus aureus Metabolic Adaptations during the Transition from a Daptomycin Susceptibility Phenotype to a Daptomycin Nonsusceptibility Phenotype

    Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

    Dr Greg A Somerville, Dr Robert Powers, Rosmarie Gaupp

  50. Meet Our Editor

    Article • Current Metabolomics, May 2015, Bentham Science Publishers

    Dr Robert Powers

  51. Preface: “The Whole is Greater Than the Sum of its Parts.” - Aristotle

    Article • Current Metabolomics, May 2015, Bentham Science Publishers

    Dr Robert Powers

  52. Faculty of 1000 evaluation for Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

    Article • March 2015, Faculty of 1000, Ltd.

    Dr Robert Powers

  53. Editorial

    Article • Current Metabolomics, April 2014, Bentham Science Publishers

    Dr Robert Powers

  54. Simultaneous phase and scatter correction for NMR datasets

    Article • Chemometrics and Intelligent Laboratory Systems, February 2014, Elsevier

    Dr Robert Powers

  55. Revisiting Protocols for the NMR Analysis of Bacterial Metabolomes

    Article • Journal of Integrated OMICS, December 2013, Proteomass

    Dr Robert Powers, Rosmarie Gaupp

  56. Growth and Preparation of Staphylococcus epidermidis for NMR Metabolomic Analysis

    Article • October 2013, Springer Science + Business Media

    Dr Greg A Somerville, Dr Robert Powers

  57. NMR Metabolomics Analysis of Parkinson's Disease

    Article • Current Metabolomics, September 2013, Bentham Science Publishers

    Dr Robert Powers

  58. Faculty of 1000 evaluation for Digestion and depletion of abundant proteins improves proteomic coverage.

    Article • February 2013, Faculty of 1000, Ltd.

    Dr Robert Powers

  59. Faculty of 1000 evaluation for Metabolite-enabled eradication of bacterial persisters by aminoglycosides.

    Article • February 2013, Faculty of 1000, Ltd.

    Dr Robert Powers

  60. NMR in Drug Discovery – Introduction

    Article • January 2013, Springer Science + Business Media

    Dr Robert Powers

  61. Fragment Screen

    Article • January 2013, Springer Science + Business Media

    Dr Robert Powers

  62. SAR by NMR

    Article • January 2013, Springer Science + Business Media

    Dr Robert Powers

  63. The Applicability of Molecular Descriptors for Designing an Electrospray Ionization Mass Spectrometry Compatible Library for Drug Discovery

    Article • Combinatorial Chemistry & High Throughput Screening, November 2012, Bentham Science Publishers

    Dr Robert Powers

  64. Editorial

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  65. Editorial

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  66. Multivariate Analysis in Metabolomics

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  67. Multivariate Analysis in Metabolomics

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Dr Robert Powers

  68. Sample Preparation of Mycobacterium tuberculosis Extracts for Nuclear Magnetic Resonance Metabolomic Studies

    Article • Journal of Visualized Experiments, September 2012, MyJove Corporation

    Dr Robert Powers

  69. Application of NMR Metabolomics to Search for Human Disease Biomarkers

    Article • Combinatorial Chemistry & High Throughput Screening, August 2012, Bentham Science Publishers

    Dr Robert Powers

  70. Analysis of bacterial biofilms using NMR-based metabolomics

    Article • Future Medicinal Chemistry, June 2012, Future Science

    Dr Robert Powers

  71. Predicting the in Vivo Mechanism of Action for Drug Leads Using NMR Metabolomics

    Article • ACS Chemical Biology, January 2012, American Chemical Society (ACS)

    Dr Robert Powers

  72. An inexpensive high-throughput nuclear magnetic resonance tube cleaning apparatus

    Article • Analytical Biochemistry, September 2011, Elsevier

    Dr Robert Powers, Dr Bo Zhang

  73. Faculty of 1000 evaluation for Paper spray for direct analysis of complex mixtures using mass spectrometry.

    Article • August 2011, Faculty of 1000, Ltd.

    Dr Robert Powers

  74. Bacterial protein structures reveal phylum dependent divergence

    Article • Computational Biology and Chemistry, February 2011, Elsevier

    Dr Robert Powers

  75. Faculty of 1000 evaluation for A transient and low-populated protein-folding intermediate at atomic resolution.

    Article • December 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  76. Faculty of 1000 evaluation for Enzymatic transition states and dynamic motion in barrier crossing.

    Article • December 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  77. Faculty of 1000 evaluation for Molecular docking and ligand specificity in fragment-based inhibitor discovery.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  78. Faculty of 1000 evaluation for Evaluation of virtual screening as a tool for chemical genetic applications.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  79. Faculty of 1000 evaluation for Mapping of ligand-binding cavities in proteins.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  80. Faculty of 1000 evaluation for A hybrid clustering of protein binding sites.

    Article • May 2010, Faculty of 1000, Ltd.

    Dr Robert Powers

  81. Analysis of metabolomic PCA data using tree diagrams

    Article • Analytical Biochemistry, April 2010, Elsevier

    Dr Robert Powers

  82. Faculty of 1000 evaluation for Systems biology: an evolving approach in drug discovery and development.

    Article • October 2009, Faculty of 1000, Ltd.

    Dr Robert Powers

  83. Advances in nuclear magnetic resonance for drug discovery

    Article • Expert Opinion on Drug Discovery, August 2009, Informa Healthcare

    Dr Robert Powers

  84. Faculty of 1000 evaluation for Structure and energetics of the hydrogen-bonded backbone in protein folding.

    Article • July 2009, Faculty of 1000, Ltd.

    Dr Robert Powers

  85. NMR metabolomics and drug discovery

    Article • Magnetic Resonance in Chemistry, June 2009, Wiley

    Dr Robert Powers

  86. Faculty of 1000 evaluation for Metabolite identification via the Madison Metabolomics Consortium Database.

    Article • May 2009, Faculty of 1000, Ltd.

    Dr Robert Powers

  87. Faculty of 1000 evaluation for Binding similarity network of ligand.

    Article • June 2008, Faculty of 1000, Ltd.

    Dr Robert Powers

  88. Faculty of 1000 evaluation for Protein dispensability and rate of evolution.

    Article • December 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  89. Functional Genomics and NMR Spectroscopy

    Article • Combinatorial Chemistry & High Throughput Screening, September 2007, Bentham Science Publishers

    Dr Robert Powers

  90. Faculty of 1000 evaluation for Enzyme function less conserved than anticipated.

    Article • July 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  91. Faculty of 1000 evaluation for Intrinsic errors in genome annotation.

    Article • July 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  92. Faculty of 1000 evaluation for Discovering high-affinity ligands for proteins: SAR by NMR.

    Article • July 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  93. Faculty of 1000 evaluation for Evolutionary rate in the protein interaction network.

    Article • April 2007, Faculty of 1000, Ltd.

    Dr Robert Powers

  94. APPLICATIONS OF NUCLEAR MAGNETIC RESONANCE AND MASS SPECTROMETRY TO ANTICANCER DRUG DISCOVERY

    Article • January 2006, Elsevier

    Dr Robert Powers

  95. Solution structure of the tumor necrosis factor receptor-1 death domain

    Article • Journal of Molecular Biology, July 2001, Elsevier

    Dr Robert Powers

  96. Analysis of the backbone dynamics of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase using nitrogen-15 relaxation measurements

    Article • Biochemistry, September 1992, American Chemical Society (ACS)

    Dr G. Marius Clore, Dr Robert Powers

  97. Three-Dimensional Solution Structure of Human Interleukin-4 by Multidimensional Heteronuclear Magnetic Resonance Spectroscopy

    Article • Science, June 1992, American Association for the Advancement of Science

    Dr Robert Powers

  98. Proton, nitrogen-15, carbon-13, carbon-13 monoxide assignments of human interleukin-4 using three-dimensional double- and triple-resonance heteronuclear magnetic resonance spectroscopy

    Article • Biochemistry, May 1992, American Chemical Society (ACS)

    Dr G. Marius Clore, Dr Robert Powers

  99. Determination of the secondary structure and folding topology of human interleukin-4 using three-dimensional heteronuclear magnetic resonance spectroscopy

    Article • Biochemistry, May 1992, American Chemical Society (ACS)

    Dr G. Marius Clore, Dr Robert Powers

  100. Secondary structure of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase in solution using three-dimensional double and triple resonance heteronuclear magnetic resonance spectroscopy

    Article • Journal of Molecular Biology, October 1991, Elsevier

    Dr G. Marius Clore, Dr Robert Powers

  101. A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams

    Article • Journal of Magnetic Resonance (1969), October 1991, Elsevier

    Dr Robert Powers

  102. Three-dimensional triple-resonance NMR of 13C/15N-enriched proteins using constant-time evolution

    Article • Journal of Magnetic Resonance (1969), August 1991, Elsevier

    Dr G. Marius Clore, Dr Robert Powers

  103. Two-dimensional proton and phosphorus-31 NMR spectra and restrained molecular dynamics structure of a covalent CPI-CDPI2-oligodeoxyribonucleotide decamer complex

    Article • Biochemistry, October 1990, American Chemical Society (ACS)

    Dr Robert Powers

  104. Introduction to NMR and Its Application in Metabolite Structure Determination

    Article • Wiley

    Dr Robert Powers