All Stories

  1. MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity

    Article • eLife, January 2020, eLife

    Renumathy Dhanasekaran

  2. Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection Is Associated With Increased Survival in Patients With a History of Hepatocellular Carcinoma

    Article • Gastroenterology, November 2019, Elsevier

    Renumathy Dhanasekaran

  3. The Immune Landscape of Cancer

    Article • Immunity, August 2019, Elsevier

    Renumathy Dhanasekaran

  4. A Tale of Two Complications of Obesity: NASH and Hepatocellular Carcinoma

    Article • Hepatology, May 2019, Wiley

    Renumathy Dhanasekaran

  5. Direct-Acting Antiviral Therapy Not Associated With Recurrence of Hepatocellular Carcinoma in a Multicenter North American Cohort Study

    Article • Gastroenterology, May 2019, Elsevier

    Renumathy Dhanasekaran

  6. Genomic Medicine and Implications for Hepatocellular Carcinoma Prevention and Therapy

    Article • Gastroenterology, January 2019, Elsevier

    Renumathy Dhanasekaran

  7. Lipid nanoparticles that deliver IL-12 messenger RNA suppress tumorigenesis in MYC oncogene-driven hepatocellular carcinoma

    Article • Journal for ImmunoTherapy of Cancer, November 2018, Springer Science + Business Media

    Renumathy Dhanasekaran

  8. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

    Article • Cell Systems, October 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  9. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

    Article • Cell Reports, October 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  10. Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

    Article • Cancer Cell, August 2018, Elsevier

    Renumathy Dhanasekaran

  11. Comprehensive Characterization of Cancer Driver Genes and Mutations

    Article • Cell, August 2018, Elsevier

    Renumathy Dhanasekaran

  12. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

    Article • Cell Reports, June 2018, Elsevier

    Renumathy Dhanasekaran

  13. Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

    Article • Cell Reports, April 2018, Elsevier

    Professor Casey Greene, Renumathy Dhanasekaran, Dr Ronald E Warnick

  14. Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Article • Cell, April 2018, Elsevier

    Professor Casey Greene, Renumathy Dhanasekaran, Dr Ronald E Warnick

  15. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

    Article • Cancer Cell, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  16. A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran

  17. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  18. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  19. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

    Article • Cancer Cell, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  20. Comprehensive Characterization of Cancer Driver Genes and Mutations

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran

  21. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  22. Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Article • Cancer Cell, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  23. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran

  24. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  25. Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  26. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran

  27. Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  28. Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran

  29. Pathogenic Germline Variants in 10,389 Adult Cancers

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran

  30. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

    Article • Cell, April 2018, Elsevier

    Renumathy Dhanasekaran

  31. Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran

  32. Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  33. Systematic Analysis of Splice-Site-Creating Mutations in Cancer

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran

  34. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

    Article • Cell Reports, April 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  35. The Immune Landscape of Cancer

    Article • Immunity, April 2018, Elsevier

    Renumathy Dhanasekaran

  36. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

    Article • Cancer Cell, April 2018, Elsevier

    Renumathy Dhanasekaran

  37. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Article • Cell Systems, March 2018, Elsevier

    Renumathy Dhanasekaran

  38. Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

    Article • Cell Systems, March 2018, Elsevier

    Renumathy Dhanasekaran, Dr Ronald E Warnick

  39. YAP-associated chromosomal instability and cholangiocarcinoma in mice

    Article • Oncotarget, December 2017, Impact Journals, LLC

    Renumathy Dhanasekaran

  40. Ribosomal protein S15a promotes tumor angiogenesis via enhancing Wnt/β-catenin-induced FGF18 expression in hepatocellular carcinoma

    Article • Oncogene, December 2017, Springer Science + Business Media

    Renumathy Dhanasekaran

  41. Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC)

    Article • Oncotarget, November 2017, Impact Journals, LLC

    Renumathy Dhanasekaran

  42. Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    Article • Cell, June 2017, Elsevier

    Renumathy Dhanasekaran

  43. Management of Immunosuppression in Liver Transplantation

    Article • Clinics in Liver Disease, May 2017, Elsevier

    Renumathy Dhanasekaran

  44. Selective Internal Yttrium-90 Radioembolization Therapy (90Y-SIRT) Versus Best Supportive Care in Patients With Unresectable Metastatic Melanoma to the Liver Refractory to Systemic Therapy

    Article • American Journal of Clinical Oncology, February 2017, Wolters Kluwer Health

    Renumathy Dhanasekaran

  45. Bridging Locoregional Therapy Prolongs Survival in Patients Listed for Liver Transplant with Hepatocellular Carcinoma

    Article • CardioVascular and Interventional Radiology, November 2016, Springer Science + Business Media

    Renumathy Dhanasekaran

  46. Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

    Article • Cancer Research, November 2016, American Association for Cancer Research (AACR)

    Renumathy Dhanasekaran

  47. Primary Carcinoma of the Liver

    Article • August 2016, Wiley

    Renumathy Dhanasekaran

  48. Erratum to “Clinical implications of basic research in hepatocellular carcinoma” [J Hepatol 2016;64:736–745]

    Article • Journal of Hepatology, June 2016, Elsevier

    Renumathy Dhanasekaran

  49. Pathogenesis of HCC

    Article • F1000Research, May 2016, Faculty of 1000, Ltd.

    Renumathy Dhanasekaran, Lewis Roberts

  50. Sa1362 Identification of Novel Fusions in Gallbladder Cancer by Next Generation Sequencing RNA Analysis - Potential for Targeted Therapy

    Article • Gastroenterology, April 2016, Elsevier

    Renumathy Dhanasekaran

  51. Clinical implications of basic research in hepatocellular carcinoma

    Article • Journal of Hepatology, March 2016, Elsevier

    Renumathy Dhanasekaran

  52. Response to Fibrosis progression in patients treated for hepatitis C recurrence

    Article • Liver International, November 2015, Wiley

    Renumathy Dhanasekaran

  53. Quality of Cancer Care in Patients with Cirrhosis and Hepatocellular Carcinoma

    Article • Current Gastroenterology Reports, August 2015, Springer Science + Business Media

    Renumathy Dhanasekaran

  54. Impact of fibrosis progression on clinical outcome in patients treated for post- transplant hepatitis C recurrence

    Article • Liver International, July 2015, Wiley

    Renumathy Dhanasekaran

  55. Sa1858 Undiagnosed Nonalcoholic Steatohepatitis (NASH) Is Responsible for a Significant Proportion of Cryptogenic Hepatocellular Carcinoma (HCC)

    Article • Gastroenterology, April 2015, Elsevier

    Renumathy Dhanasekaran

  56. 585 Comparative Efficacy of Transarterial Radioembolization (TARE) Versus Chemotherapy or Best Supportive Care for Unresectable Intrahepatic Cholangiocarcinoma (iCCA)

    Article • Gastroenterology, April 2015, Elsevier

    Renumathy Dhanasekaran

  57. Sa1716 Next Generation Sequencing and Pathway Analysis Reveals Frequent Activation of the PI3-K/Akt Pathway in Gallbladder Cancer: Potential for Targeted Therapy

    Article • Gastroenterology, April 2015, Elsevier

    Renumathy Dhanasekaran

  58. Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma

    Article • Hepatology, February 2015, Wiley

    Renumathy Dhanasekaran

  59. Liver Transplantation for Hepatocellular Carcinoma

    Article • Current Transplantation Reports, September 2014, Springer Science + Business Media

    Renumathy Dhanasekaran

  60. Vasodilator-stimulated phosphoprotein promotes activation of hepatic stellate cells by regulating Rab11-dependent plasma membrane targeting of transforming growth factor beta receptors

    Article • Hepatology, September 2014, Wiley

    Renumathy Dhanasekaran

  61. 639 Female Gender Associated With Less Aggressive Tumor Phenotype and Better Survival in HCC

    Article • Gastroenterology, May 2014, Elsevier

    Renumathy Dhanasekaran

  62. 770 Sulfatase2 (SULF2) Promotes Angiogenesis in Hepatocellular Carcinoma Partly Through the TGFβ1/Periostin Signaling Pathway

    Article • Gastroenterology, May 2014, Elsevier

    Renumathy Dhanasekaran

  63. Challenges of recurrent hepatitis C in the liver transplant patient

    Article • World Journal of Gastroenterology, January 2014, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Renumathy Dhanasekaran

  64. Response to Houlihan et al.

    Article • The American Journal of Gastroenterology, November 2013, Nature

    Renumathy Dhanasekaran

  65. Mo1847 Analysis of Paired Biopsies to Assess Progression of Fibrosis in Patients Treated for Post-Transplant Hepatitis C Recurrence

    Article • Gastroenterology, May 2013, Elsevier

    Renumathy Dhanasekaran

  66. Mo1891 Rate and Predictors of Progression and Mortality in a Large Population Based Cohort of Be

    Article • Gastroenterology, May 2013, Elsevier

    Renumathy Dhanasekaran

  67. Tu1039 Is NASH Related HCC Different From HCC Related to Other Causes

    Article • Gastroenterology, May 2013, Elsevier

    Renumathy Dhanasekaran

  68. Safety and Efficacy of Doxorubicin Drug-eluting Bead Transarterial Chemoembolization in Patients with Advanced Hepatocellular Carcinoma

    Article • Journal of Vascular and Interventional Radiology, March 2013, Elsevier

    Renumathy Dhanasekaran

  69. Treatment outcomes and prognostic factors of intrahepatic cholangiocarcinoma

    Article • Oncology Reports, February 2013, Spandidos Publications

    Renumathy Dhanasekaran

  70. Hepatic Preservation Injury: Severity of Hepatitis C Recurrence and Survival After Liver Transplantation

    Article • Digestive Diseases and Sciences, January 2013, Springer Science + Business Media

    Renumathy Dhanasekaran

  71. Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates

    Article • Case Reports in Hepatology, January 2013, Hindawi Publishing Corporation

    Renumathy Dhanasekaran

  72. Incidentally Discovered HCC (iHCC) in Explant Liver-Histopathologic Features and Clinical Outcome

    Article • Journal of Cancer Therapy, January 2013, Scientific Research Publishing, Inc,

    Renumathy Dhanasekaran

  73. Chemoembolization Combined with RFA for HCC:Survival Benefits and Tumor Treatment Response

    Article • Journal of Cancer Therapy, January 2013, Scientific Research Publishing, Inc,

    Renumathy Dhanasekaran

  74. Influence of transjugular intrahepatic portosystemic shunt in patients awaiting orthotopic liver transplant on post-transplant outcome

    Article • Gastrointestinal Intervention, December 2012, Elsevier

    Renumathy Dhanasekaran

  75. Predictors of early mortality post transjugular intrahepatic portosystemic shunts and the role of hepatic venous pressure gradient

    Article • Gastrointestinal Intervention, December 2012, Elsevier

    Renumathy Dhanasekaran

  76. Liver Test Results Do Not Identify Liver Disease in Adults With α1-Antitrypsin Deficiency

    Article • Clinical Gastroenterology and Hepatology, November 2012, Elsevier

    Renumathy Dhanasekaran

  77. Impact of Transarterial Therapy in Hepatitis C-Related Hepatocellular Carcinoma on Long-term Outcomes After Liver Transplantation

    Article • American Journal of Clinical Oncology, August 2012, Wolters Kluwer Health

    Renumathy Dhanasekaran

  78. Prognostic Value of 18F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Predicting Survival in Patients with Unresectable Metastatic Melanoma to the Liver Undergoing Yttrium-90 Radioembolization

    Article • Journal of Vascular and Interventional Radiology, July 2012, Elsevier

    Renumathy Dhanasekaran

  79. Emerging Therapies for Hepatocellular Carcinoma

    Article • January 2012, Springer Science + Business Media

    Renumathy Dhanasekaran

  80. Rare Case of Adult Undifferentiated (Embryonal) Sarcoma of the Liver Treated with Liver Transplantation: Excellent Long-Term Survival

    Article • Case Reports in Hepatology, January 2012, Hindawi Publishing Corporation

    Renumathy Dhanasekaran

  81. Tumoral and angiogenesis factors in hepatocellular carcinoma after locoregional therapy

    Article • Pathology - Research and Practice, January 2012, Elsevier

    Renumathy Dhanasekaran

  82. The Effectiveness of Locoregional Therapies versus Supportive Care in Maintaining Survival within the Milan Criteria in Patients with Hepatocellular Carcinoma

    Article • Journal of Vascular and Interventional Radiology, August 2010, Elsevier

    Renumathy Dhanasekaran

  83. S1920 Influence of Patient Age on Short Term and Long Term Survival After Tips

    Article • Gastroenterology, May 2010, Elsevier

    Renumathy Dhanasekaran

  84. Prognostic factors for survival in patients with unresectable hepatocellular carcinoma undergoing chemoembolization with doxorubicin drug-eluting beads: a preliminary study

    Article • HPB, April 2010, Elsevier

    Renumathy Dhanasekaran

  85. Comparison of conventional transarterial chemoembolization (TACE) and chemoembolization with doxorubicin drug eluting beads (DEB) for unresectable hepatocelluar carcinoma (HCC)

    Article • Journal of Surgical Oncology, January 2010, Wiley

    Renumathy Dhanasekaran

  86. Transjugular Intrahepatic Portosystemic Shunt for Symptomatic Refractory Hepatic Hydrothorax in Patients With Cirrhosis

    Article • The American Journal of Gastroenterology, November 2009, Nature

    Renumathy Dhanasekaran