All Stories

  1. Defining glycoproteoform landscapes through an integrated glycoproteomics approach enabled by high-resolving power proton transfer charge reduction tandem mass spectrometry
  2. The microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism
  3. GlycoDiveR: A Modular R Framework to Analyze and Visualize Highly Dimensional Glycoproteomics Data
  4. GlycoDiveR: a modular R framework to analyze and visualize highly dimensional glycoproteomics data
  5. Understanding m / z Range Settings for MS/MS Scans: A Case Study with Intact Glycopeptides
  6. Profiling Glycoproteins Enriched by Multinanoparticle Protein Corona
  7. The protease Cathepsin K can debulk the cancer glycocalyx
  8. Extracting Informative Glycan-Specific Ions From Glycopeptide MS/MS Spectra With GlyCounter
  9. Sialoglycans on human T cells attenuate death programs executed through the Fas pathway
  10. Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
  11. Profiling glycoproteins enriched by multi-nanoparticle protein corona
  12. Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides
  13. Profiling glycoproteins enriched by surface-functionalized nanoparticles
  14. Sialoglycans on human T cells attenuate death programs executed through the Fas pathway
  15. Accelerating the stride toward functional glycoproteomics
  16. Improvements in Glycoproteomics through Architecture Changes to the Orbitrap Tribrid MS Platform
  17. Publisher Correction: irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
  18. Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides
  19. irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
  20. Extracting informative glycan-specific ions from glycopeptide MS/MS spectra with GlyCounter
  21. Comparative analysis of glycoproteomic software using a tailored glycan database
  22. Revisiting the Effect of Trypsin Digestion Buffers on Artificial Deamidation
  23. Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
  24. Autonomous Dissociation-type Selection for Glycoproteomics Using a Real-Time Library Search
  25. Sialylated glycoproteins suppress immune cell killing by binding to Siglec-7 and Siglec-9 in prostate cancer
  26. “Comparative Analysis of Glycoproteomic Software Using a Tailored Glycan Database”
  27. Instrumentation at the Leading Edge of Proteomics
  28. Instrumentation at the leading edge of proteomics
  29. Instrumentation at the leading edge of proteomics
  30. Microglia Mediate Contact-Independent Neuronal Network Remodeling via Secreted Neuraminidase-3 Associated with Extracellular Vesicles
  31. Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
  32. Galectin-3 does not interact with RNA directly
  33. Microglia mediate contact-independent neuronal pruning via secreted Neuraminidase-3 associated with extracellular vesicles
  34. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
  35. Organism-wide, cell-type-specific secretome mapping of exercise training in mice
  36. The microenvironment dictates glycocalyx construction and immune surveillance
  37. Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity
  38. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  39. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  40. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  41. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  42. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  43. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  44. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  45. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  46. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  47. Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  48. Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  49. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  50. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  51. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  52. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  53. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  54. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  55. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  56. MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
  57. The 2022 Nobel Prize in Chemistry—sweet!
  58. Measuring the multifaceted roles of mucin-domain glycoproteins in cancer
  59. Organism-wide secretome mapping uncovers pathways of tissue crosstalk in exercise
  60. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  61. Antibody-lectin chimeras for glyco-immune checkpoint blockade
  62. The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
  63. Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
  64. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  65. Glycoproteomics
  66. Revealing the human mucinome
  67. Targeting hypersialylation in multiple myeloma represents a novel approach to enhance NK cell–mediated tumor responses
  68. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
  69. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
  70. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  71. Practical Effects of Intramolecular Hydrogen Rearrangement in Electron Transfer Dissociation-Based Proteomics
  72. Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  73. Protocol for cell type-specific labeling, enrichment, and proteomic profiling of plasma proteins in mice
  74. The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
  75. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
  76. Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
  77. Revealing the human mucinome
  78. Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
  79. Modulation of immune cell reactivity with cis -binding Siglec agonists
  80. A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry–Based Glycoproteomics
  81. Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
  82. Cell type-selective secretome profiling in vivo
  83. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
  84. O-Pair Search with MetaMorpheus for O-glycopeptide characterization
  85. Cell type-selective secretome profiling in vivo
  86. Optical Fiber-Enabled Photoactivation of Peptides and Proteins
  87. Lysosome Targeting Chimeras (LYTACs) That Engage a Liver-Specific Asialoglycoprotein Receptor for Targeted Protein Degradation
  88. Lysosome-targeting chimaeras for degradation of extracellular proteins
  89. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
  90. Top-Down Characterization of an Intact Monoclonal Antibody Using Activated Ion Electron Transfer Dissociation
  91. Optimal Dissociation Methods Differ for N- and O-Glycopeptides
  92. Optimal Dissociation Methods Differ for N- and O-glycopeptides
  93. O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
  94. Optimal Dissociation Methods Differ for N- and O-glycopeptides
  95. Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes
  96. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  97. Broad and thematic remodeling of the surface glycoproteome on isogenic cells transformed with driving proliferative oncogenes
  98. Mutating stress-defense regulators in yeast improves biofuels engineering
  99. Interactive Peptide Spectral Annotator: A Versatile Web-Based Tool for Proteomic Applications
  100. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  101. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  102. Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis
  103. Rewired cellular signaling coordinates sugar and hypoxic responses for anaerobic xylose fermentation in yeast
  104. Top-Down Characterization of Proteins with Intact Disulfide Bonds Using Activated-Ion Electron Transfer Dissociation
  105. The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins
  106. Improved Precursor Characterization for Data-Dependent Mass Spectrometry
  107. The Role of Electron Transfer Dissociation in Modern Proteomics
  108. Sequencing Larger Intact Proteins (30-70 kDa) with Activated Ion Electron Transfer Dissociation
  109. Activated Ion-Electron Transfer Dissociation Enables Comprehensive Top-Down Protein Fragmentation
  110. Negative Electron Transfer Dissociation Sequencing of Increasingly Sulfated Glycosaminoglycan Oligosaccharides on an Orbitrap Mass Spectrometer
  111. Implementation of Activated Ion Electron Transfer Dissociation on a Quadrupole-Orbitrap-Linear Ion Trap Hybrid Mass Spectrometer
  112. Phosphoproteomics with Activated Ion Electron Transfer Dissociation
  113. Sulfur Pentafluoride is a Preferred Reagent Cation for Negative Electron Transfer Dissociation
  114. Multi-omics Evidence for Inheritance of Energy Pathways in Red Blood Cells
  115. Full-Featured Search Algorithm for Negative Electron-Transfer Dissociation
  116. Genome Sequence and Analysis of a Stress-Tolerant, Wild-Derived Strain of Saccharomyces cerevisiae Used in Biofuels Research
  117. Proteomics Moves into the Fast Lane
  118. Mitochondrial protein hyperacetylation in the failing heart
  119. Enhanced Dissociation of Intact Proteins with High Capacity Electron Transfer Dissociation
  120. Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling
  121. The Negative Mode Proteome with Activated Ion Negative Electron Transfer Dissociation (AI-NETD)
  122. A Calibration Routine for Efficient ETD in Large-Scale Proteomics
  123. Activated Ion Electron Transfer Dissociation for Improved Fragmentation of Intact Proteins
  124. Coupling Capillary Zone Electrophoresis with Electron Transfer Dissociation and Activated Ion Electron Transfer Dissociation for Top-Down Proteomics
  125. Neutron-Encoded Mass Signatures for Quantitative Top-Down Proteomics