All Stories

  1. Extracting Informative Glycan-Specific Ions From Glycopeptide MS/MS Spectra With GlyCounter
  2. Sialoglycans on human T cells attenuate death programs executed through the Fas pathway
  3. Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
  4. Profiling glycoproteins enriched by multi-nanoparticle protein corona
  5. Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides
  6. Profiling glycoproteins enriched by surface-functionalized nanoparticles
  7. Sialoglycans on human T cells attenuate death programs executed through the Fas pathway
  8. Accelerating the stride toward functional glycoproteomics
  9. Improvements in Glycoproteomics through Architecture Changes to the Orbitrap Tribrid MS Platform
  10. Publisher Correction: irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
  11. Understanding m/z range settings for MS/MS scans: a case study with intact glycopeptides
  12. irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
  13. Extracting informative glycan-specific ions from glycopeptide MS/MS spectra with GlyCounter
  14. Comparative analysis of glycoproteomic software using a tailored glycan database
  15. Revisiting the Effect of Trypsin Digestion Buffers on Artificial Deamidation
  16. Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
  17. Autonomous Dissociation-type Selection for Glycoproteomics Using a Real-Time Library Search
  18. Sialylated glycoproteins suppress immune cell killing by binding to Siglec-7 and Siglec-9 in prostate cancer
  19. “Comparative Analysis of Glycoproteomic Software Using a Tailored Glycan Database”
  20. Instrumentation at the Leading Edge of Proteomics
  21. Instrumentation at the leading edge of proteomics
  22. Instrumentation at the leading edge of proteomics
  23. Microglia Mediate Contact-Independent Neuronal Network Remodeling via Secreted Neuraminidase-3 Associated with Extracellular Vesicles
  24. Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
  25. Galectin-3 does not interact with RNA directly
  26. Microglia mediate contact-independent neuronal pruning via secreted Neuraminidase-3 associated with extracellular vesicles
  27. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
  28. Organism-wide, cell-type-specific secretome mapping of exercise training in mice
  29. The microenvironment dictates glycocalyx construction and immune surveillance
  30. Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity
  31. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  32. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  33. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  34. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  35. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  36. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  37. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  38. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  39. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  40. Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  41. Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  42. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  43. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  44. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  45. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  46. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  47. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  48. Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  49. MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
  50. The 2022 Nobel Prize in Chemistry—sweet!
  51. Measuring the multifaceted roles of mucin-domain glycoproteins in cancer
  52. Organism-wide secretome mapping uncovers pathways of tissue crosstalk in exercise
  53. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  54. Antibody-lectin chimeras for glyco-immune checkpoint blockade
  55. The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
  56. Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
  57. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  58. Glycoproteomics
  59. Revealing the human mucinome
  60. Targeting hypersialylation in multiple myeloma represents a novel approach to enhance NK cell–mediated tumor responses
  61. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
  62. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
  63. Deciphering O-glycoprotease substrate preferences with O-Pair Search
  64. Practical Effects of Intramolecular Hydrogen Rearrangement in Electron Transfer Dissociation-Based Proteomics
  65. Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge
  66. Protocol for cell type-specific labeling, enrichment, and proteomic profiling of plasma proteins in mice
  67. The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
  68. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
  69. Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
  70. Revealing the human mucinome
  71. Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
  72. Modulation of immune cell reactivity with cis -binding Siglec agonists
  73. A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry–Based Glycoproteomics
  74. Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
  75. Cell type-selective secretome profiling in vivo
  76. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
  77. O-Pair Search with MetaMorpheus for O-glycopeptide characterization
  78. Cell type-selective secretome profiling in vivo
  79. Optical Fiber-Enabled Photoactivation of Peptides and Proteins
  80. Lysosome Targeting Chimeras (LYTACs) That Engage a Liver-Specific Asialoglycoprotein Receptor for Targeted Protein Degradation
  81. Lysosome-targeting chimaeras for degradation of extracellular proteins
  82. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
  83. Top-Down Characterization of an Intact Monoclonal Antibody Using Activated Ion Electron Transfer Dissociation
  84. Optimal Dissociation Methods Differ for N- and O-Glycopeptides
  85. Optimal Dissociation Methods Differ for N- and O-glycopeptides
  86. O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
  87. Optimal Dissociation Methods Differ for N- and O-glycopeptides
  88. Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes
  89. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  90. Broad and thematic remodeling of the surface glycoproteome on isogenic cells transformed with driving proliferative oncogenes
  91. Mutating stress-defense regulators in yeast improves biofuels engineering
  92. Interactive Peptide Spectral Annotator: A Versatile Web-Based Tool for Proteomic Applications
  93. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  94. Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins
  95. Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis
  96. Rewired cellular signaling coordinates sugar and hypoxic responses for anaerobic xylose fermentation in yeast
  97. Top-Down Characterization of Proteins with Intact Disulfide Bonds Using Activated-Ion Electron Transfer Dissociation
  98. The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins
  99. Improved Precursor Characterization for Data-Dependent Mass Spectrometry
  100. The Role of Electron Transfer Dissociation in Modern Proteomics
  101. Sequencing Larger Intact Proteins (30-70 kDa) with Activated Ion Electron Transfer Dissociation
  102. Activated Ion-Electron Transfer Dissociation Enables Comprehensive Top-Down Protein Fragmentation
  103. Negative Electron Transfer Dissociation Sequencing of Increasingly Sulfated Glycosaminoglycan Oligosaccharides on an Orbitrap Mass Spectrometer
  104. Implementation of Activated Ion Electron Transfer Dissociation on a Quadrupole-Orbitrap-Linear Ion Trap Hybrid Mass Spectrometer
  105. Phosphoproteomics with Activated Ion Electron Transfer Dissociation
  106. Sulfur Pentafluoride is a Preferred Reagent Cation for Negative Electron Transfer Dissociation
  107. Multi-omics Evidence for Inheritance of Energy Pathways in Red Blood Cells
  108. Full-Featured Search Algorithm for Negative Electron-Transfer Dissociation
  109. Genome Sequence and Analysis of a Stress-Tolerant, Wild-Derived Strain of Saccharomyces cerevisiae Used in Biofuels Research
  110. Proteomics Moves into the Fast Lane
  111. Mitochondrial protein hyperacetylation in the failing heart
  112. Enhanced Dissociation of Intact Proteins with High Capacity Electron Transfer Dissociation
  113. Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling
  114. The Negative Mode Proteome with Activated Ion Negative Electron Transfer Dissociation (AI-NETD)
  115. A Calibration Routine for Efficient ETD in Large-Scale Proteomics
  116. Activated Ion Electron Transfer Dissociation for Improved Fragmentation of Intact Proteins
  117. Coupling Capillary Zone Electrophoresis with Electron Transfer Dissociation and Activated Ion Electron Transfer Dissociation for Top-Down Proteomics
  118. Neutron-Encoded Mass Signatures for Quantitative Top-Down Proteomics