All Stories

  1. Structure and activity of a thermally stable mutant of Acanthamoeba actophorin

    Article • Acta Crystallographica Section F Structural Biology Communications, March 2022, International Union of Crystallography

    Raquel Lieberman

  2. Improved resolution crystal structure of Acanthamoeba actophorin reveals structural plasticity not induced by microgravity

    Article • Acta Crystallographica Section F Structural Biology Communications, November 2021, International Union of Crystallography

    Raquel Lieberman

  3. Calcium-ligand variants of the myocilin olfactomedin propeller selected from invertebrate phyla reveal cross-talk with N-terminal blade and surface helices

    Article • Acta Crystallographica Section D Structural Biology, August 2019, International Union of Crystallography

    Raquel Lieberman

  4. How does a protein’s structure spell the difference between health and disease? Our journey to understand glaucoma-associated myocilin

    Article • PLoS Biology, April 2019, PLOS

    Raquel Lieberman

  5. Progress toward development of a proteostasis drug for myocilin-associated glaucoma

    Article • Future Medicinal Chemistry, May 2018, Future Science

    Raquel Lieberman

  6. Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments

    Article • Proteins Structure Function and Bioinformatics, March 2014, Wiley

    Raquel Lieberman, Thomas Truskett

  7. myocilin amyloid fibrils

    Article • Journal of Molecular Biology, February 2014, Elsevier

    Raquel Lieberman

  8. Non-Native Structural Properties of the Glaucoma-Associated Olfactomedin Domain of Myocilin Lead to Amyloid Fibrils

    Article • Biophysical Journal, January 2013, Elsevier

    Raquel Lieberman

  9. New direction for glaucoma therapeutics: focus on the olfactomedin domain of myocilin

    Article • Future Medicinal Chemistry, November 2012, Future Science

    Raquel Lieberman

  10. Determination of Soluble and Membrane Protein Structures by X-Ray Crystallography

    Article • October 2012, Springer Science + Business Media

    Raquel Lieberman

  11. Crystallization chaperone strategies for membrane proteins

    Article • Methods, December 2011, Elsevier

    Raquel Lieberman, Prof Jennifer A Maynard

  12. A Guided Tour of the Structural Biology of Gaucher Disease: Acid-β-Glucosidase and Saposin C

    Article • Enzyme Research, November 2011, Hindawi Publishing Corporation

    Raquel Lieberman

  13. Binding of 3,4,5,6-Tetrahydroxyazepanes to the Acid-β-glucosidase Active Site: Implications for Pharmacological Chaperone Design for Gaucher Disease

    Article • Biochemistry, November 2011, American Chemical Society (ACS)

    Raquel Lieberman

  14. The Stability of Myocilin Olfactomedin Domain Variants Provides New Insight into Glaucoma as a Protein Misfolding Disorder

    Article • Biochemistry, June 2011, American Chemical Society (ACS)

    Raquel Lieberman

  15. Biophysical Characterization of the Olfactomedin Domain of Myocilin, an Extracellular Matrix Protein Implicated in Inherited Forms of Glaucoma

    Article • PLoS ONE, January 2011, PLOS

    Raquel Lieberman

  16. Rescue of Glaucoma-Causing Mutant Myocilin Thermal Stability by Chemical Chaperones

    Article • ACS Chemical Biology, March 2010, American Chemical Society (ACS)

    Raquel Lieberman

  17. Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability

    Article • Biochemistry, May 2009, American Chemical Society (ACS)

    Raquel Lieberman

  18. Structure of acid β-glucosidase with pharmacological chaperone provides insight into Gaucher disease

    Article • Nature Chemical Biology, December 2006, Springer Science + Business Media

    Raquel Lieberman

  19. Characterization of the Particulate Methane Monooxygenase Metal Centers in Multiple Redox States by X-ray Absorption Spectroscopy

    Article • Inorganic Chemistry, August 2006, American Chemical Society (ACS)

    Raquel Lieberman

  20. X-ray Crystallography and Biological Metal Centers:  Is Seeing Believing?

    Article • Inorganic Chemistry, January 2005, American Chemical Society (ACS)

    Raquel Lieberman

  21. Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane

    Article • January 2005

    Raquel Lieberman

  22. The quest for the particulate methane monooxygenase active site

    Article • Dalton Transactions, January 2005, Royal Society of Chemistry

    Raquel Lieberman

  23. Biological Methane Oxidation: Regulation, Biochemistry, and Active Site Structure of Particulate Methane Monooxygenase

    Article • Critical Reviews in Biochemistry and Molecular Biology, January 2004, Taylor & Francis

    Raquel Lieberman

  24. Crystal Structure of a Novel Red Copper Protein from Nitrosomonas europaea,

    Article • Biochemistry, April 2001, American Chemical Society (ACS)

    Raquel Lieberman

  25. Synthesis, structure and magnetic properties of a chromium(III)nicotinamide complex [Cr3O(O2CCH3)6(na)3]+ (na=nicotinamide)

    Article • Inorganica Chimica Acta, January 2000, Elsevier

    Raquel Lieberman, Professor Avi Bino