All Stories

  1. Rationally Engineered Small Molecules: Pharmacophore Modeling and Molecular Docking Studies Targeting Toxic Polyglutamine (PolyQ) Repeats in Huntington’s Disease
  2. Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching
  3. Transcriptomic profile in carbendazim-induced developmental defects in zebrafish (Danio rerio) embryos/larvae
  4. Correction: Reddy et al. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells 2023, 12, 1646
  5. DDQ Anti-aging properties expressed with improved mitophagy in mutant Tau HT22 neuronal cells
  6. Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights
  7. Protective function of StAR in amyloid-β accumulated hippocampal neurotoxicity and neurosteroidogenesis: Mechanistic insights into Alzheimer's disease
  8. Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications
  9. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights
  10. A study on antimicrobial and anticancer properties of Cissus Quadrangulris using lung Cancer cell line.
  11. A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease
  12. Mitochondria in Aging and Alzheimer’s Disease: Focus on Mitophagy
  13. Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer
  14. Methods to Study Mitochondria: Techniques Used to Study the Effects of Age‐Related Diseases Including Alzheimer's
  15. Food bioactive compounds, sources, and their effectiveness during COVID-19
  16. MicroRNAs and COVID-19
  17. Transcriptomic profiling identified altered expression of genes associated with testicular functions in adult F1 rats exposed to carbimazole during fetal period
  18. Purification, Structural Elucidation, and Anticancerous Properties of a Novel Flavonoid from Flowers of Leucas indica
  19. Regulation of retinoid mediated StAR transcription and steroidogenesis in hippocampal neuronal cells: Implications for StAR in protecting Alzheimer's disease
  20. A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer’s Disease
  21. A partial reduction of VDAC1 enhances mitophagy, autophagy, synaptic activities in a transgenic Tau mouse model
  22. Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
  23. Immobilization stress exacerbates arsenic-induced reprotoxic effects in adult rats
  24. Are mitophagy enhancers therapeutic targets for Alzheimer’s disease?
  25. Sunflower-Assisted Bio-Derived ZnO-NPs as an Efficient Nanocatalyst for the Synthesis of Novel Quinazolines with Highly Antioxidant Activities
  26. Early Cellular, Molecular, Morphological and Behavioral Changes in the Humanized Amyloid-Beta-Knock-In Mouse Model of Late-Onset Alzheimer’s Disease
  27. MicroRNA-455-3p improves synaptic, cognitive functions and extends lifespan: Relevance to Alzheimer's disease
  28. SmartBin system with waste tracking and sorting mechanism using IoT
  29. Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease
  30. Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse
  31. Pharmacological Potentiality of Bioactive Flavonoid against Ketamine Induced Cell Death of PC 12 Cell Lines: An In Vitro Study
  32. Therapeutic potentiality of a new flavonoid against ketamine induced glutamatergic dysregulation in schizophrenia: In vivo and in silico approach
  33. Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and Tauopathies
  34. Mitochondrial Dysfunctioning Induced by Hyperglycemia in the Liver Tissues of Diabetic Mice, TALLYHO/JngJ Strain and Ameliorative Action of a Small Peptide, SS31
  35. Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice
  36. Introduction to brucellosis
  37. Identification and characterization of vaccine targets for Brucella melitensis through in silico approaches
  38. Computational modeling and evaluation of best potential drug targets through comparative modeling
  39. Molecular docking and dynamics simulations of novel drug targets
  40. In silico validation and ADMET analysis for the best lead molecules
  41. Summary and conclusions
  42. Front Matter
  43. OUP accepted manuscript
  44. Beneficial effects of polyherbal formulation (Bronco-T) on formaldehyde-induced lung toxicity in male Wistar rats
  45. Defective Mitophagy in Alzheimer’s Disease
  46. Trigonella foenum-graecum seeds extract plays a beneficial role on brain antioxidant and oxidative status in alloxan-induced Wistar rats
  47. Phenotypic and trascriptomic changes in zebrafish (Danio rerio) embryos/larvae following cypermethrin exposure
  48. Synthesis, biological evaluation and molecular docking studies of novel di-hydropyridine analogs as potent antioxidants
  49. Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer's Disease
  50. Insights of rheumatoid arthritis risk factors and associations
  51. Current Status of Healthy Aging and Dementia Research: A Symposium Summary
  52. Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer’s Disease
  53. Bioflavonoid hesperidin possesses the anti-hyperglycemic and hypolipidemic property in STZ induced diabetic myocardial infarction (DMI) in male Wister rats
  54. Aquaculture role in global food security with nutritional value: a review
  55. Three Novel Mutations I65S, R66S, and G86R Divulge Significant Conformational Variations in the PTB Domain of the IRS1 Gene
  56. Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer’s disease
  57. Analysis of aflatoxin B1 in contaminated feed, media, and serum samples of Cyprinus carpio L. by high-performance liquid chromatography
  58. Conformational transition pathway of R308K mutant glucokinase in the presence of the glucokinase activator YNKGKA4
  59. Discovery of small molecules through pharmacophore modeling, docking and molecular dynamics simulation against Plasmodium vivax Vivapain-3 (VP-3)
  60. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer’s disease
  61. Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer’s Disease
  62. Multiplex quantification of Escherichia coli, Salmonella typhi and Vibrio cholera with three DNA targets in single reaction assay
  63. Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity
  64. Modeling, molecular docking, probing catalytic binding mode of acetyl-CoA malate synthase G in Brucella melitensis 16M
  65. Calcium, zinc and vitamin E ameliorate cadmium-induced renal oxidative damage in albino Wistar rats
  66. Selenoergothionein as a Potential Inhibitor against Amyloid β-Protein (Aβ): Docking and Molecular Dynamics Studies
  67. Environmental Acidification Impact on Fisheries by Changing Oxidative Markers of Liver and Intestine of Freshwater Fish Cyprinus Carpio.L
  68. Multiplex PCR assay for the simultaneous detection of C. perfringens, P. aeruginosa and K. pneumoniae
  69. CGMD: An integrated database of cancer genes and markers
  70. Complete genome-wide screening and subtractive genomic approach revealed new virulence factors, potential drug targets against bio-war pathogen Brucella melitensis 16M
  71. Modeling, molecular dynamics, and docking assessment of transcription factor rho: a potential drug target in Brucella melitensis 16M
  72. Analysis of polymorphism in Kir 6.2 gene in Type 2 diabetic patients
  73. Comparison and correlation of binding mode of ATP in the kinase domains of Hexokinase family
  74. Comparison and correlation of Simple Sequence Repeats distribution in genomes of Brucella species
  75. Summary and Conclusions