All Stories

  1. Rationally Engineered Small Molecules: Pharmacophore Modeling and Molecular Docking Studies Targeting Toxic Polyglutamine (PolyQ) Repeats in Huntington’s Disease

    Article • Current Drug Targets, October 2025, Bentham Science Publishers

    Dr Pradeepkiran Jangampalli Adi

  2. Overexpressed MicroRNA-455-3p enhances cognitive function in late-onset Alzheimer’s disease

    Article • Brain Research, October 2025, Elsevier

    Dr Pradeepkiran Jangampalli Adi

  3. Small molecule DDQ involvement of ERK-mediated signaling pathway with enhanced mitophagy in HT22 cells transfected with mTau

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2025, Elsevier

    Dr Pradeepkiran Jangampalli Adi

  4. Therapeutic potential of DDQ in enhancing mitochondrial health and cognitive function in Late-Onset Alzheimer’s disease

    Article • Mitochondrion, July 2025, Elsevier

    Dr Pradeepkiran Jangampalli Adi

  5. Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching

    Article • Neural Regeneration Research, June 2024, Medknow

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  6. Transcriptomic profile in carbendazim-induced developmental defects in zebrafish (Danio rerio) embryos/larvae

    Article • Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, June 2024, Elsevier

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  7. Antioxidant effects of α-lipoic acid against epididymal oxidative damage in adult offspring rats exposed to maternal hypothyroidism stress

    Article • Reproductive Toxicology, April 2024, Elsevier

    Dr Pradeepkiran Jangampalli Adi

  8. Comprehensive structural and functional analysis of hVEGFR1: Insights into phosphorylation, molecular interactions, and potential inhibitors through docking and dynamics simulations

    Article • Cancer Treatment and Research Communications, January 2024, Elsevier

    Dr Pradeepkiran Jangampalli Adi

  9. Amyloid-β and Phosphorylated Tau are the Key Biomarkers and Predictors of Alzheimer’s Disease

    Article • Aging and Disease, January 2024, Aging and Disease

    Dr Pradeepkiran Jangampalli Adi

  10. Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, October 2023, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  11. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights

    Article • Cells, June 2023, MDPI AG

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  12. Mitochondria in Aging and Alzheimer’s Disease: Focus on Mitophagy

    Article • The Neuroscientist, January 2023, SAGE Publications

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  13. Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  14. Methods to Study Mitochondria: Techniques Used to Study the Effects of Age‐Related Diseases Including Alzheimer's

    Article • Current Protocols, January 2023, Wiley

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  15. Transcriptomic profiling identified altered expression of genes associated with testicular functions in adult F1 rats exposed to carbimazole during fetal period

    Article • Journal of Proteomics, December 2022, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  16. Purification, Structural Elucidation, and Anticancerous Properties of a Novel Flavonoid from Flowers of Leucas indica

    Article • Processes, November 2022, MDPI AG

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  17. Regulation of retinoid mediated StAR transcription and steroidogenesis in hippocampal neuronal cells: Implications for StAR in protecting Alzheimer's disease

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, November 2022, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  18. A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer’s Disease

    Article • Cells, August 2022, MDPI AG

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  19. Immobilization stress exacerbates arsenic-induced reprotoxic effects in adult rats

    Article • Toxicology Research, May 2022, Oxford University Press (OUP)

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  20. Are mitophagy enhancers therapeutic targets for Alzheimer’s disease?

    Article • Biomedicine & Pharmacotherapy, May 2022, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  21. MicroRNA-455-3p improves synaptic, cognitive functions and extends lifespan: Relevance to Alzheimer's disease

    Article • Redox Biology, December 2021, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  22. SmartBin system with waste tracking and sorting mechanism using IoT

    Article • Cleaner Engineering and Technology, December 2021, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  23. Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease

    Article • Human Molecular Genetics, August 2021, Oxford University Press (OUP)

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  24. Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse

    Article • Free Radical Biology and Medicine, July 2021, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  25. Pharmacological Potentiality of Bioactive Flavonoid against Ketamine Induced Cell Death of PC 12 Cell Lines: An In Vitro Study

    Article • Antioxidants, June 2021, MDPI AG

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  26. Therapeutic potentiality of a new flavonoid against ketamine induced glutamatergic dysregulation in schizophrenia: In vivo and in silico approach

    Article • Biomedicine & Pharmacotherapy, June 2021, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  27. Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and Tauopathies

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, April 2021, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  28. Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer's Disease

    Article • Human Molecular Genetics, October 2019, Oxford University Press (OUP)

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  29. Insights of rheumatoid arthritis risk factors and associations

    Article • Journal of Translational Autoimmunity, August 2019, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  30. Current Status of Healthy Aging and Dementia Research: A Symposium Summary

    Article • Journal of Alzheimer’s Disease, May 2019, IOS Press

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  31. Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer’s Disease

    Article • Cells, March 2019, MDPI AG

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  32. Bioflavonoid hesperidin possesses the anti-hyperglycemic and hypolipidemic property in STZ induced diabetic myocardial infarction (DMI) in male Wister rats

    Article • Journal of Nutrition & Intermediary Metabolism, March 2019, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  33. Aquaculture role in global food security with nutritional value: a review

    Article • Translational Animal Science, March 2019, Oxford University Press (OUP)

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  34. Three Novel Mutations I65S, R66S, and G86R Divulge Significant Conformational Variations in the PTB Domain of the IRS1 Gene

    Article • ACS Omega, January 2019, American Chemical Society (ACS)

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  35. Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer’s disease

    Article • Drug Discovery Today, November 2018, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  36. Analysis of aflatoxin B1 in contaminated feed, media, and serum samples of Cyprinus carpio L. by high-performance liquid chromatography

    Article • Food Quality and Safety, July 2018, Oxford University Press (OUP)

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  37. Conformational transition pathway of R308K mutant glucokinase in the presence of the glucokinase activator YNKGKA4

    Article • FEBS Open Bio, July 2018, Wiley

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  38. Discovery of small molecules through pharmacophore modeling, docking and molecular dynamics simulation against Plasmodium vivax Vivapain-3 (VP-3)

    Article • Heliyon, May 2018, Elsevier

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  39. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer’s disease

    Article • Human Molecular Genetics, April 2018, Oxford University Press (OUP)

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  40. Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, January 2018, IOS Press

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  41. Multiplex quantification of Escherichia coli, Salmonella typhi and Vibrio cholera with three DNA targets in single reaction assay

    Article • Microbial Pathogenesis, September 2017, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  42. Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Ramesh Kandimalla, Madhu Sudhana Saddala, Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  43. Modeling, molecular docking, probing catalytic binding mode of acetyl-CoA malate synthase G in Brucella melitensis 16M

    Article • Biochemistry and Biophysics Reports, December 2016, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  44. Calcium, zinc and vitamin E ameliorate cadmium-induced renal oxidative damage in albino Wistar rats

    Article • Toxicology Reports, January 2016, Elsevier

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  45. Selenoergothionein as a Potential Inhibitor against Amyloid β-Protein (Aβ): Docking and Molecular Dynamics Studies

    Article • International Journal of Biomedical Data Mining, January 2016, OMICS Publishing Group

    Madhu Sudhana Saddala, Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  46. Environmental Acidification Impact on Fisheries by Changing Oxidative Markers of Liver and Intestine of Freshwater Fish Cyprinus Carpio.L

    Article • Poultry Fisheries & Wildlife Sciences, January 2016, OMICS Publishing Group

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  47. Multiplex PCR assay for the simultaneous detection of C. perfringens, P. aeruginosa and K. pneumoniae

    Article • Pathogenesis, November 2015, Elsevier

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  48. CGMD: An integrated database of cancer genes and markers

    Article • Scientific Reports, July 2015, Nature

    Dr., Pradeepkiran Jangampalli Adi, Dr Pradeepkiran Jangampalli Adi

  49. Complete genome-wide screening and subtractive genomic approach revealed new virulence factors, potential drug targets against bio-war pathogen Brucella melitensis 16M

    Article • Drug Design Development and Therapy, March 2015, Dove Medical Press

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  50. Modeling, molecular dynamics, and docking assessment of transcription factor rho: a potential drug target in Brucella melitensis 16M

    Article • Drug Design Development and Therapy, March 2015, Dove Medical Press

    Dr Pradeepkiran Jangampalli Adi, Dr Nanda Kumar Yellapu, Dr., Pradeepkiran Jangampalli Adi

  51. Comparison and correlation of binding mode of ATP in the kinase domains of Hexokinase family

    Article • Bioinformation, June 2012, Biomedical Informatics

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi

  52. Comparison and correlation of Simple Sequence Repeats distribution in genomes of Brucella species

    Article • Bioinformation, May 2011, Biomedical Informatics

    Dr Pradeepkiran Jangampalli Adi, Dr., Pradeepkiran Jangampalli Adi