All Stories

  1. The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation
  2. Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface
  3. ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
  4. Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)
  5. TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions
  6. Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth
  7. RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly
  8. Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes
  9. Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms to de-repress VEGF-signalling genes and promote cell survival
  10. The Transcription Factor Encyclopedia
  11. DNA compaction by the higher-order assembly of PRH/Hex homeodomain protein oligomers
  12. PRH/Hhex Controls Cell Survival through Coordinate Transcriptional Regulation of Vascular Endothelial Growth Factor Signaling
  13. CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding
  14. The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors