All Stories

  1. Detecting mir-155-3p through a Molecular Beacon Bead-Based Assay
  2. Evaluation of miR-155 silencing using a molecular beacon in human lung adenocarcinoma cell line
  3. Discovery of novel fluorescent azaindoles with cytotoxic action in A2780 ovarian carcinoma cells
  4. Mild hyperthermia via gold nanoparticles and visible light irradiation for enhanced siRNA and ASO delivery in 2D and 3D tumour spheroids
  5. Copper(II) Complexes with 2,2′:6′,2″-Terpyridine Derivatives Displaying Dimeric Dichloro−μ–Bridged Crystal Structure: Biological Activities from 2D and 3D Tumor Spheroids to In Vivo Models
  6. Exploiting Co(III)-Cyclopentadienyl Complexes To Develop Anticancer Agents
  7. Anti-inflammatory and antiproliferative activity of Helichrysum odoratissimum Sweet. against lung cancer
  8. Assessing the gene silencing potential of AuNP-based approaches on conventional 2D cell culture versus 3D tumor spheroid
  9. Doxorubicin-sensitive and -resistant colorectal cancer spheroid models: assessing tumor microenvironment features for therapeutic modulation
  10. Tackling Imatinib Resistance via Au‐nanoconjugates using A Cml Resistant Cell Line
  11. Half-sandwich Ru(II) N-heterocyclic carbene complexes in anticancer drug design
  12. Epidermal growth factor alters silica nanoparticle uptake and improves gold-nanoparticle-mediated gene silencing in A549 cells
  13. In Vitro and In Vivo Biological Activities of Dipicolinate Oxovanadium(IV) Complexes
  14. Hybrid Digital-Droplet Microfluidic Chip for Applications in Droplet Digital Nucleic Acid Amplification: Design, Fabrication and Characterization
  15. Parylene C as a Multipurpose Material for Electronics and Microfluidics
  16. Combining the amplification refractory mutation system and high-resolution melting analysis for KRAS mutation detection in clinical samples
  17. Exploring RAB11A Pathway to Hinder Chronic Myeloid Leukemia-Induced Angiogenesis In Vivo
  18. Cell Uptake of Steroid-BODIPY Conjugates and Their Internalization Mechanisms: Cancer Theranostic Dyes
  19. Open-source tool for real-time and automated analysis of droplet-based microfluidic
  20. Short Lecture 4 “Evaluation of antiproliferative and anti-angiogenic activity of an ethanolic extract of Helichrysum odoratissimum (L.) Sweet against skin cancer”
  21. Antiproliferative Activity of Buddleja saligna (Willd.) against Melanoma and In Vivo Modulation of Angiogenesis
  22. In Vitro and In Vivo Biological Activity of Ruthenium 1,10-Phenanthroline-5,6-dione Arene Complexes
  23. Editorial: Rational drug design of metal complexes for cancer therapy
  24. Engineering gold nanoparticles for molecular diagnostics and biosensing
  25. Digital Microfluidics for Amplification Monitoring of Cancer Biomarkers
  26. Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker
  27. Endogenous Fluorescent Proteins in the Mucus of an Intertidal Polychaeta: Clues for Biotechnology
  28. Molecular Beacon for Detection miRNA-21 as a Biomarker of Lung Cancer
  29. Light Triggered Enhancement of Antibiotic Efficacy in Biofilm Elimination Mediated by Gold-Silver Alloy Nanoparticles
  30. A solvent‐free strategy to prepare amorphous salts of folic acid with enhanced solubility and cell permeability
  31. Quercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment
  32. Boron clusters (ferrabisdicarbollides) shaping the future as radiosensitizers for multimodal (chemo/radio/PBFR) therapy of glioblastoma
  33. Genetic Biomarkers in Chronic Myeloid Leukemia: What Have We Learned So Far?
  34. Aggregation versus Biological Activity in Gold(I) Complexes. An Unexplored Concept
  35. New Non-Toxic N-alkyl Cholinium-Based Ionic Liquids as Excipients to Improve the Solubility of Poorly Water-Soluble Drugs
  36. Manganese(I) tricarbonyl complexes as potential anticancer agents
  37. Vanadium(IV) Complexes with Methyl-Substituted 8-Hydroxyquinolines: Catalytic Potential in the Oxidation of Hydrocarbons and Alcohols with Peroxides and Biological Activity
  38. Square planar Au(III), Pt(II) and Cu(II) complexes with quinoline-substituted 2,2′:6′,2″-terpyridine ligands: From in vitro to in vivo biological properties
  39. Inflammatory factors, genetic variants , and predisposition for preterm birth
  40. Genetic predisposition for aggressive behaviour related with dopamine and serotonin pathways – an overview
  41. The genetic susceptibility linking preterm birth and periodontal disease – a review
  42. Liposomal Nanosystems in Rheumatoid Arthritis
  43. Drug delivery nanosystems targeted to hepatic ischemia and reperfusion injury
  44. In Vitro and In Vivo Effect of Palladacycles: Targeting A2780 Ovarian Carcinoma Cells and Modulation of Angiogenesis
  45. Rosa x hybrida extracts with dual actions: Antiproliferative effects against tumour cells and inhibitor of Alzheimer disease
  46. Combined cancer therapeutics—Tackling the complexity of the tumor microenvironment
  47. A Transcriptomic Approach to the Recruitment of Venom Proteins in a Marine Annelid
  48. Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid Eulalia sp. onto Ovarian Cancer Cells
  49. Exploiting the antiproliferative potential of spiropyrazoline oxindoles in a human ovarian cancer cell line
  50. Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action
  51. Benchtop X-ray fluorescence imaging as a tool to study gold nanoparticle penetration in 3D cancer spheroids
  52. Copper(ii) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups and ligand flexibility on antiproliferative activities
  53. Water safety screening via multiplex LAMP-Au-nanoprobe integrated approach
  54. Nano‐in‐Micro Sildenafil Dry Powder Formulations for the Treatment of Pulmonary Arterial Hypertension Disorders: The Synergic Effect of POxylated Polyurea Dendrimers, PLGA, and Cholesterol
  55. Hyperthermia Induced by Gold Nanoparticles and Visible Light Photothermy Combined with Chemotherapy to Tackle Doxorubicin Sensitive and Resistant Colorectal Tumor 3D Spheroids
  56. Tackling Multidrug Resistance in Streptococci – From Novel Biotherapeutic Strategies to Nanomedicines
  57. The Intracellular Number of Magnetic Nanoparticles Modulates the Apoptotic Death Pathway after Magnetic Hyperthermia Treatment
  58. Gold Nanoparticles for Vectorization of Nucleic Acids for Cancer Therapeutics
  59. Nanotheranostics in Gene Therapy
  60. Synthesis of new hetero-arylidene-9(10H)-anthrone derivatives and their biological evaluation
  61. Nano‐in‐Micro Sildenafil Dry Powder Formulations for the Treatment of Pulmonary Arterial Hypertension Disorders: The Synergic Effect of POxylated Polyurea Dendrimers, PLGA, and Cholesterol
  62. Fast Prototyping Microfluidics: Integrating Droplet Digital Lamp for Absolute Quantification of Cancer Biomarkers
  63. Gene Therapy in Cancer Treatment: Why Go Nano?
  64. Size-Dependent Biological Activities of Fluorescent Organosilane-Modified Zinc Oxide Nanoparticles
  65. Antiproliferative Activities of Diimine-Based Mixed Ligand Copper(II) Complexes
  66. Improving the Anti-inflammatory Response via Gold Nanoparticle Vectorization of CO-Releasing Molecules
  67. RNA Quantification Using Noble Metal Nanoprobes: Simultaneous Identification of Several Different mRNA Targets Using Color Multiplexing and Application to Chronic Myeloid Leukemia Diagnostics
  68. Paper-Based SERS Platform for One-Step Screening of Tetracycline in Milk
  69. Light Irradiation of Gold Nanoparticles Toward Advanced Cancer Therapeutics
  70. Cation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessment
  71. Targeting Cancer Resistance via Multifunctional Gold Nanoparticles
  72. Antiproliferative activity of heterometallic sodium and potassium-dioxidovanadium(V) polymers
  73. Structural characterization and biological properties of silver(I) tris(pyrazolyl)methane sulfonate
  74. Nanotheranostics Targeting the Tumor Microenvironment
  75. Counteracting the effect of leukemia exosomes by antiangiogenic gold nanoparticles
  76. Occurrence of non-toxic bioemulsifiers during polyhydroxyalkanoate production by Pseudomonas strains valorizing crude glycerol by-product
  77. Ionic Liquids and Salts from Ibuprofen as Promising Innovative Formulations of an Old Drug
  78. Structural aspects of a trimetallic CuII derivative: cytotoxicity and anti-proliferative activity on human cancer cell lines
  79. Enhancement of water solubility of poorly water-soluble drugs by new biocompatible N-acetyl amino acid N-alkyl cholinium-based ionic liquids
  80. New lessons from ancient life: marine invertebrates as a source of new drugs
  81. Targeting Tumor Microenvironment for Cancer Therapy
  82. GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach
  83. Antibody modified gold nanoparticles for fast colorimetric screening of rheumatoid arthritis
  84. A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
  85. Front Cover: The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes (Chem. Eur. J. 55/2018)
  86. The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes
  87. The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes
  88. Cover Feature: POxylated Dendrimer-Based Nano-in-Micro Dry Powder Formulations for Inhalation Chemotherapy (ChemistryOpen 10/2018)
  89. A double Philadelphia chromosome-positive chronic myeloid leukemia patient, co-expressing P210BCR-ABL1 and P195BCR-ABL1 isoforms
  90. Combination of chemotherapy and Au-nanoparticle photothermy in the visible light to tackle doxorubicin resistance in cancer cells
  91. Gold nanoprobe-based non-crosslinking hybridization for molecular diagnostics: an update
  92. POxylated Dendrimer‐Based Nano‐in‐Micro Dry Powder Formulations for Inhalation Chemotherapy
  93. Nano-Strategies to Fight Multidrug Resistant Bacteria—“A Battle of the Titans”
  94. Evaluation of cell toxicity and DNA and protein binding of green synthesized silver nanoparticles
  95. Optical and Structural Characterization of a Chronic Myeloid Leukemia DNA Biosensor
  96. Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells
  97. Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero‐Arylidene‐9(10H)‐Anthrone
  98. Multifunctional microfluidic chip for optical nanoprobe based RNA detection – application to Chronic Myeloid Leukemia
  99. Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma
  100. Allele specific LAMP- gold nanoparticle for characterization of single nucleotide polymorphisms
  101. Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles
  102. A Digital Microfluidics Platform for Loop-Mediated Isothermal Amplification Detection
  103. Photothermal enhancement of chemotherapy in breast cancer by visible irradiation of Gold Nanoparticles
  104. Digital Microfluidics for Nucleic Acid Amplification
  105. Gold Nanoparticles for BCR-ABL1 Gene Silencing: Improving Tyrosine Kinase Inhibitor Efficacy in Chronic Myeloid Leukemia
  106. Quantitative real-time monitoring of RCA amplification of cancer biomarkers mediated by a flexible ion sensitive platform
  107. Smuggling gold nanoparticles across cell types – A new role for exosomes in gene silencing
  108. Gold Nanoparticle Approach to the Selective Delivery of Gene Silencing in Cancer—The Case for Combined Delivery?
  109. Targeting canine mammary tumours via gold nanoparticles functionalized with promising Co(II) and Zn(II) compounds
  110. Tumor Microenvironment Modulation via Gold Nanoparticles Targeting Malicious Exosomes: Implications for Cancer Diagnostics and Therapy
  111. Gold Nanobeacons for Tracking Gene Silencing in Zebrafish
  112. Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents
  113. Gene Silencing Using Multifunctionalized Gold Nanoparticles for Cancer Therapy
  114. Gold Nanoparticles in Molecular Diagnostics and Molecular Therapeutics
  115. Current trends in molecular diagnostics of chronic myeloid leukemia
  116. Gold Nanoparticles for Diagnostics: Advances towards Points of Care
  117. Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo
  118. Colorimetric assessment of BCR-ABL1 transcripts in clinical samples via gold nanoprobes
  119. BioCode gold-nanobeacon for the detection of fusion transcripts causing chronic myeloid leukemia
  120. Immortalization and characterization of a new canine mammary tumour cell line FR37-CMT
  121. Infection of human keratinocytes by Streptococcus dysgalactiae subspecies dysgalactiae isolated from milk of the bovine udder
  122. Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy
  123. Synthesis, characterization, thermal properties and antiproliferative potential of copper(ii) 4′-phenyl-terpyridine compounds
  124. In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(iv) complex
  125. Heteroleptic mononuclear compounds of ruthenium(ii): synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos
  126. A novel mutation inCEBPAgene in a patient with acute myeloid leukemia
  127. Gold Nanotheranostics: Proof-of-Concept or Clinical Tool?
  128. Scalable approach for the production of functional DNA based gold nanoprobes
  129. Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box
  130. Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles
  131. Gold nanoprobe-based non-crosslinking hybridization for molecular diagnostics
  132. One nanoprobe, two pathogens: gold nanoprobes multiplexing for point-of-care
  133. Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects
  134. 15 years on siRNA delivery: Beyond the State-of-the-Art on inorganic nanoparticles for RNAi therapeutics
  135. Characterization of antiproliferative potential and biological targets of a copper compound containing 4′-phenyl terpyridine
  136. POxylated Polyurea Dendrimers: Smart Core-Shell Vectors with IC50Lowering Capacity
  137. Field Effect Sensors for Nucleic Acid Detection: Recent Advances and Future Perspectives
  138. Gold nanoparticle-based theranostics: disease diagnostics and treatment using a single nanomaterial
  139. Nanoparticles for Diagnostics and Imaging
  140. DNA adduct identification using gold-aptamer nanoprobes
  141. Single nucleotide polymorphism detection using gold nanoprobes and bio-microfluidic platform with embedded microlenses
  142. RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing
  143. Mobile Based Gold Nanoprobe TB Diagnostics for Point-of-Need
  144. Characterization of genomic single nucleotide polymorphism via colorimetric detection using a single gold nanoprobe
  145. Metabolic and histopathological alterations in the marine bivalve Mytilus galloprovincialis induced by chronic exposure to acrylamide
  146. Anti-cancer precision theranostics: a focus on multifunctional gold nanoparticles
  147. Gold nanobeacons: a potential nanotheranostics platform
  148. A promising road with challenges: where are gold nanoparticles in translational research?
  149. Cancer therapy
  150. AuNPs for identification of molecular signatures of resistance
  151. Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine
  152. Antibody–drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranostics
  153. Dual-color control of nucleotide polymerization sensed by a fluorescence actuator
  154. Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis
  155. A low cost, safe, disposable, rapid and self-sustainable paper-based platform for diagnostic testing: lab-on-paper
  156. Ion sensing (EIS) real-time quantitative monitorization of isothermal DNA amplification
  157. Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies
  158. Star-shaped magnetite@gold nanoparticles for protein magnetic separation and SERS detection
  159. Exosome in Tumour Microenvironment: Overview of the Crosstalk between Normal and Cancer Cells
  160. Histopathological findings onCarassius auratushepatopancreas upon exposure to acrylamide: correlation with genotoxicity and metabolic alterations
  161. In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models
  162. Coupling an universal primer to SBE combined spectral codification strategy for single nucleotide polymorphism analysis
  163. Bio-microfluidic platform for gold nanoprobe based DNA detection—application to Mycobacterium tuberculosis
  165. Association of FTO and PPARG polymorphisms with obesity in Portuguese women
  166. Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis
  167. Gold-nanobeacons for simultaneous gene specific silencing and intracellular tracking of the silencing events
  168. Fast nucleotide identification through fingerprinting using gold nanoparticle-based surface-assisted laser desorption/ionisation
  169. Nanomaterials for reversion of multidrug resistance in cancer: a new hope for an old idea?
  170. Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis
  171. Modification of plasmid DNA topology by ‘histone-mimetic’ gold nanoparticles
  172. Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing
  173. Could gold nanoprobes be an important tool in cancer diagnostics?
  174. Gold-nanobeacons for real-time monitoring of RNA synthesis
  175. Gold and silver nanoparticles for clinical diagnostics — From genomics to proteomics
  176. Effect of PEG biofunctional spacers and TAT peptide on dsRNA loading on gold nanoparticles
  177. Enhancement of antibiotic effect via gold:silver-alloy nanoparticles
  178. Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis
  179. RNA Quantification with Gold Nanoprobes for Cancer Diagnostics
  180. Noble Metal Nanoparticles for Biosensing Applications
  181. Gold on paper–paper platform for Au-nanoprobe TB detection
  182. RNA Quantification Using Noble Metal Nanoprobes: Simultaneous Identification of Several Different mRNA Targets Using Color Multiplexing and Application to Cancer Diagnostics
  183. Noble Metal Nanoparticles Applications in Cancer
  184. Nanophotonics for Molecular Diagnostics and Therapy Applications
  185. Gold nanoparticle-based fluorescence immunoassay for malaria antigen detection
  186. Real-time monitoring of PCR amplification of proto-oncogene c-MYC using a Ta2O5 electrolyte–insulator–semiconductor sensor
  187. Experimental photophysical characterization of fluorophores in the vicinity of gold nanoparticles
  188. Coupling single base extension to a spectral codification tool for increased throughput screening
  189. Alloy metal nanoparticles for multicolor cancer diagnostics
  190. Portable optoelectronic biosensing platform for identification of mycobacteria from the Mycobacterium tuberculosis complex
  191. Nanoparticles in Molecular Diagnostics
  192. pH Effect on the Photochemistry of 4-Methylcoumarin Phosphate Esters: Caged-Phosphate Case Study
  193. In vitro transcription and translation inhibition via DNA functionalized gold nanoparticles
  194. Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis
  195. Gold nanoprobe assay for the identification of mycobacteria of the Mycobacterium tuberculosis complex
  196. New insights into the use of magnetic force microscopy to discriminate between magnetic and nonmagnetic nanoparticles
  197. Use of cyclodextrins as scavengers of inhibitory photo-products in light controlled in vitro synthesis of RNA
  198. Gold–silver-alloy nanoprobes for one-pot multiplex DNA detection
  199. Development of a fast and efficient ultrasonic-based strategy for DNA fragmentation
  200. Optimizing Au-nanoprobes for specific sequence discrimination
  201. Inkjet printed and “doctor blade” TiO2 photodetectors for DNA biosensors
  202. RNA quantification using gold nanoprobes - application to cancer diagnostics
  203. Gold nanoprobes assay for identification of mycobacteria from theMycobacterium tuberculosiscomplex
  204. General FRET-based coding for application in multiplexing methods
  205. Cancer Nanotechnology - Prospects for Cancer Diagnostics and Therapy
  206. Multiplexed spectral coding for simultaneous detection of DNA hybridization reactions based on FRET
  207. Light activation of transcription: photocaging of nucleotides for control over RNA polymerization
  208. Characterization of optoelectronic platform using an amorphous/nanocrystalline silicon biosensor for the specific identification of nucleic acid sequences based on gold nanoparticle probes
  209. Identification of unamplified genomic DNA sequences using gold nanoparticle probes and a novel thin film photodetector
  210. Gold nanoparticles for the development of clinical diagnosis methods
  211. Imaging Gold Nanoparticles for DNA Sequence Recognition in Biomedical Applications
  212. Gold Nanoparticle Based Systems in Genetics
  213. Amorphous/nanocrystalline silicon biosensor for the specific identification of unamplified nucleic acid sequences using gold nanoparticle probes
  214. Novel Optoelectronic Platform using an Amorphous/Nanocrystalline Silicon Biosensor for the Specific Identification of Unamplified Nucleic Acid Sequences Based on Gold Nanoparticle Probes
  215. Nanodiagnostics: fast colorimetric method for single nucleotide polymorphism/mutation detection
  216. Gold-Nanoparticle-Probe–Based Assay for Rapid and Direct Detection of Mycobacterium tuberculosis DNA in Clinical Samples
  217. Colorimetric detection of eukaryotic gene expression with DNA-derivatized gold nanoparticles
  218. Principles in genetic risk assessment
  219. Construction and Analysis of a Sequence-Ready Map in 4q25: Rieger Syndrome Can Be Caused by Haploinsufficiency ofRIEG, but Also by Chromosome Breaks ≈90 kb Upstream of This Gene