All Stories

  1. Counteracting the effect of leukemia exosomes by antiangiogenic gold nanoparticles
  2. Structural aspects of a trimetallic CuII derivative: cytotoxicity and anti-proliferative activity on human cancer cell lines
  3. Targeting Tumor Microenvironment for Cancer Therapy
  4. A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
  5. Front Cover: The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes (Chem. Eur. J. 55/2018)
  6. The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes
  7. The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes
  8. Cover Feature: POxylated Dendrimer-Based Nano-in-Micro Dry Powder Formulations for Inhalation Chemotherapy (ChemistryOpen 10/2018)
  9. Combination of chemotherapy and Au-nanoparticle photothermy in the visible light to tackle doxorubicin resistance in cancer cells
  10. POxylated Dendrimer‐Based Nano‐in‐Micro Dry Powder Formulations for Inhalation Chemotherapy
  11. Halilectin-3, a Lectin from the Marine Sponge Haliclona caerulea, Induces Apoptosis and Autophagy in Human Breast Cancer MCF7 Cells Through Caspase-9 Pathway and LC3-II Protein Expression
  12. Nano-Strategies to Fight Multidrug Resistant Bacteria—“A Battle of the Titans”
  13. Evaluation of cell toxicity and DNA and protein binding of green synthesized silver nanoparticles
  14. Streptococcus dysgalactiae subsp. dysgalactiae isolated from milk of the bovine udder as emerging pathogens: In vitro and in vivo infection of human cells and zebrafish as biological models
  15. Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero‐Arylidene‐9(10H)‐Anthrone
  16. Convergence of miR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells
  17. Multifunctional microfluidic chip for optical nanoprobe based RNA detection – application to Chronic Myeloid Leukemia
  18. EPR and electrochemical interpretation of bispyrazolylacetate anchored Ni(ii) and Mn(ii) complexes: cytotoxicity and anti-proliferative activity towards human cancer cell lines
  19. Important cytotoxic and cytostatic effects of new copper(i)–phosphane compounds with N,N, N,O and N,S bidentate ligands
  20. Spectroscopy, electrochemistry and antiproliferative properties of Au(iii), Pt(ii) and Cu(ii) complexes bearing modified 2,2′:6′,2′′-terpyridine ligands
  21. Synthesis of tetrahydro-1H-indolo[2,3-b]pyrrolo[3,2-c]quinolonesviaintramolecular oxidative ring rearrangement of tetrahydro-β-carbolines and their biological evaluation
  22. Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma
  23. Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles
  24. Understanding the response of Desulfovibrio desulfuricans ATCC 27774 to the electron acceptors nitrate and sulfate - biosynthetic costs modulate substrate selection
  25. Development of PLGA dry powder microparticles by supercritical CO 2 -assisted spray-drying for potential vaccine delivery to the lungs
  26. Mixed ligand aroylhydrazone and N-donor heterocyclic Lewis base Cu(II) complexes as potential antiproliferative agents
  27. Photothermal enhancement of chemotherapy in breast cancer by visible irradiation of Gold Nanoparticles
  28. Dinuclear RuII(bipy)2Derivatives: Structural, Biological, and in Vivo Zebrafish Toxicity Evaluation
  29. Gold Nanoparticles for BCR-ABL1 Gene Silencing: Improving Tyrosine Kinase Inhibitor Efficacy in Chronic Myeloid Leukemia
  30. Smuggling gold nanoparticles across cell types – A new role for exosomes in gene silencing
  31. Gold Nanoparticle Approach to the Selective Delivery of Gene Silencing in Cancer—The Case for Combined Delivery?
  32. Targeting canine mammary tumours via gold nanoparticles functionalized with promising Co(II) and Zn(II) compounds
  33. Tumor Microenvironment Modulation via Gold Nanoparticles Targeting Malicious Exosomes: Implications for Cancer Diagnostics and Therapy
  34. Gold Nanobeacons for Tracking Gene Silencing in Zebrafish
  35. Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents
  36. Gene Silencing Using Multifunctionalized Gold Nanoparticles for Cancer Therapy
  37. Copper(ii) complexes of functionalized 2,2′:6′,2′′-terpyridines and 2,6-di(thiazol-2-yl)pyridine: structure, spectroscopy, cytotoxicity and catalytic activity
  38. Gold Nanoparticles in Molecular Diagnostics and Molecular Therapeutics
  39. Current trends in molecular diagnostics of chronic myeloid leukemia
  40. Sialic acid removal from dendritic cells improves antigen cross-presentation and boosts anti-tumor immune responses
  41. Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo
  42. Colorimetric assessment of BCR-ABL1 transcripts in clinical samples via gold nanoprobes
  43. Immortalization and characterization of a new canine mammary tumour cell line FR37-CMT
  44. Infection of human keratinocytes by Streptococcus dysgalactiae subspecies dysgalactiae isolated from milk of the bovine udder
  45. Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy
  46. Non-small cell lung cancer biomarkers and targeted therapy - two faces of the same coin fostered by nanotechnology
  47. Water soluble heterometallic potassium-dioxidovanadium(V) complexes as potential antiproliferative agents
  48. Synthesis, characterization, thermal properties and antiproliferative potential of copper(ii) 4′-phenyl-terpyridine compounds
  49. In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(iv) complex
  50. Heteroleptic mononuclear compounds of ruthenium(ii): synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos
  51. An affinity triggered MRI nanoprobe for pH-dependent cell labeling
  52. A novel mutation inCEBPAgene in a patient with acute myeloid leukemia
  53. Gold Nanotheranostics: Proof-of-Concept or Clinical Tool?
  54. Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box
  55. Characterization of antiproliferative potential and biological targets of a copper compound containing 4′-phenyl terpyridine
  56. POxylated Polyurea Dendrimers: Smart Core-Shell Vectors with IC50Lowering Capacity
  57. Gold nanoparticle-based theranostics: disease diagnostics and treatment using a single nanomaterial
  58. Covalent coupling of gum arabic onto superparamagnetic iron oxide nanoparticles for MRI cell labeling: physicochemical andin vitrocharacterization
  59. A value-added exopolysaccharide as a coating agent for MRI nanoprobes
  60. MicroRNAs Based Therapy of Hypertrophic Cardiomyopathy: The Road Traveled So Far
  61. Characterization of the antiproliferative potential and biological targets of a trans ketoimine platinum complex
  62. Genetics of hypertrophic cardiomyopathy: advances and pitfalls in molecular diagnosis and therapy
  63. Cancer therapy
  64. AuNPs for identification of molecular signatures of resistance
  65. Di- and tri-organotin(IV) complexes of arylhydrazones of methylene active compounds and their antiproliferative activity
  66. Nanoparticle Drug Delivery Systems: Recent Patents and Applications in Nanomedicine
  67. Nanotechnology for Cancer Diagnostics and Therapy – An Update on Novel Molecular Players
  68. Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies
  69. Cobalt Complexes with Pyrazole Ligands as Catalyst Precursors for the Peroxidative Oxidation of Cyclohexane: X‐ray Absorption Spectroscopy Studies and Biological Applications
  70. Exosome in Tumour Microenvironment: Overview of the Crosstalk between Normal and Cancer Cells
  71. Cobalt and Zinc Compounds Bearing 1,10-Phenanthroline-5,6-dione or 1,3,5-Triaza-7-phosphaadamantane Derivatives - Synthesis, Characterization, Cytotoxicity, and Cell Selectivity Studies
  72. Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis
  73. Biological targets of new metal compounds
  74. Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib
  75. High resolution melting: improvements in the genetic diagnosis of hypertrophic cardiomyopathy in a Portuguese cohort
  76. Cobalt complexes bearing scorpionate ligands: synthesis, characterization, cytotoxicity and DNA cleavage
  77. Toward a Translational Medicine Approach for Hypertrophic Cardiomyopathy
  78. Development of imatinib and dasatinib resistance: dynamics of expression of drug transportersABCB1, ABCC1, ABCG2, MVP, and SLC22A1
  79. Semantic characterization of hypertrophic cardiomyopathy disease
  80. The RIM101 pathway has a role inSaccharomyces cerevisiaeadaptive response and resistance to propionic acid and other weak acids
  81. An e6a2 BCR-ABL fusion transcript in a CML patient having an iliac chloroma at initial presentation
  82. Saccharomyces cerevisiae Multidrug Resistance Transporter Qdr2 Is Implicated in Potassium Uptake, Providing a Physiological Advantage to Quinidine-Stressed Cells
  83. N.P.3 03 Three novel mutations of the myelin Po gene (MPZ) in Portuguese families with CMT1B
  84. The SPI1 Gene, Encoding a Glycosylphosphatidylinositol-Anchored Cell Wall Protein, Plays a Prominent Role in the Development of Yeast Resistance to Lipophilic Weak-Acid Food Preservatives
  85. Early transcriptional response of Saccharomyces cerevisiae to stress imposed by the herbicide 2,4-dichlorophenoxyacetic acid
  86. Saccharomyces cerevisiae adaptation to weak acids involves the transcription factor Haa1p and Haa1p-regulated genes
  87. A proteome analysis of the yeast response to the herbicide 2,4-dichlorophenoxyacetic acid
  88. Saccharomyces cerevisiae Multidrug Transporter Qdr2p (Yil121wp): Localization and Function as a Quinidine Resistance Determinant
  89. Activation and significance of vacuolar H+-ATPase in Saccharomyces cerevisiae adaptation and resistance to the herbicide 2,4-dichlorophenoxyacetic acid
  90. Adaptation of Saccharomyces cerevisiae to the Herbicide 2,4-Dichlorophenoxyacetic Acid, Mediated by Msn2p- and Msn4p-Regulated Genes: Important Role of SPI1
  91. Transcription patterns ofPMA1andPMA2genes and activity of plasma membrane H+-ATPase inSaccharomyces cerevisiaeduring diauxic growth and stationary phase
  92. The activity of plasma membrane H+-ATPase is strongly stimulated duringSaccharomyces cerevisiaeadaptation to growth under high copper stress, accompanying intracellular acidification
  93. Transcriptional Activation of FLR1 Gene during Saccharomyces cerevisiae Adaptation to Growth with Benomyl: Role of Yap1p and Pdr3p
  94. Glucose does not activate the plasma-membrane-bound H + -ATPase but affects pmaA transcript abundance in Aspergillus nidulans
  95. Modification of plasma membrane lipid order and H + -ATPase activity as part of the response of Saccharomyces cerevisiae to cultivation under mild and high copper stress
  96. A Copper-sensing Transcription Factor Regulates Iron Uptake Genes in Schizosaccharomyces pombe
  97. Comparative effects of Saccharomyces cerevisiae cultivation under copper stress on the activity and kinetic parameters of plasma-membrane-bound H + -ATPases PMA 1 and PMA 2
  98. Activation of the H + -ATPase in the plasma membrane of cells of Saccharomyces cerevisiae grown under mild copper stress