All Stories

  1. Synthesis of β-d-C-Galactopyranosyl Compounds Including Constrained Derivatives from Clickable Building Blocks and Evaluation as Ligands for Galectins

    Article • European Journal of Medicinal Chemistry, January 2026, Elsevier

    Paul Murphy

  2. Synthesis of an N ‐Galactosyl Norbornane Aziridine and its Potent Mixed Inhibition of Aspergillus oryzae β‐Galactosidase

    Article • ChemBioChem, October 2025, Wiley

    Paul Murphy

  3. Cover Feature: Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones (Chem. Eur. J. 36/2024)

    Article • Chemistry - A European Journal, May 2024, Wiley

    Paul Murphy

  4. Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones

    Article • Chemistry - A European Journal, May 2024, Wiley

    Paul Murphy

  5. Flow Chemistry for Synthesis of 2-(C-Glycosyl)acetates from Pyranoses via Tandem Wittig and Michael Reactions

    Article • Organic Process Research & Development, February 2024, American Chemical Society (ACS)

    Paul Murphy

  6. Beyond the Crystal Structure of Human Macrophage C-Type Lectin

    Article • Biochemistry, January 2024, American Chemical Society (ACS)

    Paul Murphy

  7. Small lectin ligands as a basis for applications in glycoscience and glycomedicine

    Article • Chemical Society Reviews, January 2024, Royal Society of Chemistry

    Paul Murphy

  8. Synthesis of C-glycoside analogues of isopropyl β-d-1-thiogalactopyranoside (IPTG) and 1-β-d-galactopyranosyl-2-methylpropane. Conformational analysis and evaluation as inhibitors of the lac repressor in E. coli and ...

    Article • Organic & Biomolecular Chemistry, January 2024, Royal Society of Chemistry

    Paul Murphy

  9. Flow chemistry based catalytic hydrogenation for improving the synthesis of 1-deoxynojirimycin (DNJ) from an l-sorbose derived precursor

    Article • Carbohydrate Research, July 2023, Elsevier

    Paul Murphy

  10. MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response

    Article • Journal of the American Chemical Society, June 2023, American Chemical Society (ACS)

    Paul Murphy

  11. Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context

    Article • Bioorganic & Medicinal Chemistry, December 2022, Elsevier

    Paul Murphy

  12. Protecting group principles suited to late stage functionalization and global deprotection in oligosaccharide synthesis

    Article • Carbohydrate Research, November 2022, Elsevier

    Paul Murphy

  13. A cell free biomembrane platform for multimodal study of influenza virus hemagglutinin and for evaluation of entry-inhibitors against hemagglutinin

    Article • Frontiers in Molecular Biosciences, October 2022, Frontiers

    Paul Murphy

  14. Natural Products as Mcl-1 Inhibitors: A Comparative Study of Experimental and Computational Modelling Data

    Article • Chemistry, September 2022, MDPI AG

    Paul Murphy

  15. An improved method for synthesis of non-symmetric triarylpyridines

    Article • Tetrahedron, August 2022, Elsevier

    Paul Murphy

  16. Natural Products as Mcl-1 Inhibitors: A Comparative Study of Experimental and Computational Modelling Data

    Article • June 2022, Springer Science + Business Media

    Paul Murphy

  17. (1R,2R,3S,4R)-1-(Acetylamino)-2,4,5-tris(acetyloxy)-1-((2S)-4-(benzyloxy)-5-oxo-2,5-dihydrofuran-2-yl)pentan-3-yl Acetate

    Article • Molbank, February 2022, MDPI AG

    Paul Murphy

  18. Exploring the Galectin Network by Light and Fluorescence Microscopy

    Article • January 2022, Springer Science + Business Media

    Paul Murphy

  19. Carbohydrate Chemistry: Critical for our Future

    Article • The Chemical Record, November 2021, Wiley

    Paul Murphy

  20. Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars

    Article • The Chemical Record, October 2021, Wiley

    Paul Murphy

  21. What is the Sugar Code?

    Article • ChemBioChem, September 2021, Wiley

    Paul Murphy

  22. 1-Tosyl-6-vinyl-4,5,6,7-tetrahydro-1H-benzo [d] imidazole-2-amine

    Article • Molbank, July 2021, MDPI AG

    Paul Murphy

  23. Immunomodulatory properties of characellide A on human peripheral blood mononuclear cells

    Article • Inflammopharmacology, July 2021, Springer Science + Business Media

    Paul Murphy, Louise Allcock

  24. Imitating evolution’s tinkering by protein engineering reveals extension of human galectin-7 activity

    Article • Histochemistry and Cell Biology, June 2021, Springer Science + Business Media

    Paul Murphy

  25. Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen

    Article • Biochemistry, March 2021, American Chemical Society (ACS)

    Paul Murphy

  26. Development of Mcl-1 inhibitors for cancer therapy

    Article • European Journal of Medicinal Chemistry, January 2021, Elsevier

    Paul Murphy

  27. Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes

    Article • iScience, January 2021, Elsevier

    Paul Murphy

  28. Building blocks from monosaccharides for synthesis of scaffolds, including macrocycles. Application of allylic azide rearrangement, azide-alkyne cycloaddition and ring closing metathesis

    Article • Tetrahedron, November 2020, Elsevier

    Paul Murphy

  29. Migrastatin analogues with an (E)-alkene at the ring C-3: synthesis, conformational analysis and biological evaluation

    Article • ARKIVOC, August 2020, ARKAT USA, Inc.

    Paul Murphy

  30. Correction to: Influence of protein (human galectin-3) design on aspects of lectin activity

    Article • Histochemistry and Cell Biology, June 2020, Springer Science + Business Media

    Paul Murphy

  31. (2S,3R,6R)-2-[(R)-1-Hydroxyallyl]-4,4-dimethoxy-6-methyltetrahydro-2H-pyran-3-ol

    Article • Molbank, June 2020, MDPI AG

    Paul Murphy

  32. Influence of protein (human galectin-3) design on aspects of lectin activity

    Article • Histochemistry and Cell Biology, April 2020, Springer Science + Business Media

    Paul Murphy

  33. Cover Feature: A Route to 1‐Deoxynojirimycin and 1‐Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α‐d‐Mannopyranoside (Eur. J. Org. Chem. 16/2020)

    Article • European Journal of Organic Chemistry, April 2020, Wiley

    Paul Murphy

  34. A Route to 1‐Deoxynojirimycin and 1‐Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α‐d‐Mannopyranoside

    Article • European Journal of Organic Chemistry, March 2020, Wiley

    Paul Murphy

  35. Microcavity array supported lipid bilayer models of ganglioside – influenza hemagglutinin1 binding

    Article • Chemical Communications, January 2020, Royal Society of Chemistry

    Paul Murphy

  36. Multi-targeting protein-protein interaction inhibitors: Evolution of macrocyclic ligands with embedded carbohydrates (MECs) to improve selectivity

    Article • European Journal of Medicinal Chemistry, August 2019, Elsevier

    Paul Murphy

  37. Synthesis and biological evaluation of S-simplexides and other analogues of simplexide

    Article • Pure and Applied Chemistry, July 2019, De Gruyter

    Paul Murphy

  38. Microcavity-Supported Lipid Membranes: Versatile Platforms for Building Asymmetric Lipid Bilayers and for Protein Recognition

    Article • ACS Applied Bio Materials, July 2019, American Chemical Society (ACS)

    Paul Murphy

  39. How altering the modular architecture affects aspects of lectin activity: case study on human galectin-1

    Article • Glycobiology, May 2019, Oxford University Press (OUP)

    Paul Murphy

  40. N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines

    Article • Bioorganic Chemistry, March 2019, Elsevier

    Paul Murphy

  41. Ligand design for somatostatin receptor isoforms 4 and 5

    Article • European Journal of Medicinal Chemistry, February 2019, Elsevier

    Paul Murphy

  42. Lewis acid promoted anomerisation of alkyl O- and S-xylo-, arabino- and fucopyranosides

    Article • Carbohydrate Research, January 2019, Elsevier

    Paul Murphy

  43. Anomer Preferences for Glucuronic and Galacturonic Acid and Derivatives and Influence of Electron-Withdrawing Substituents

    Article • The Journal of Organic Chemistry, July 2018, American Chemical Society (ACS)

    Paul Murphy

  44. Influence of acyl groups on glucopyranoside reactivity in Lewis acid promoted anomerisation

    Article • Tetrahedron Letters, July 2018, Elsevier

    Paul Murphy

  45. Revealing biomedically relevant cell and lectin type-dependent structure–activity profiles for glycoclusters by using tissue sections as an assay platform

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Paul Murphy

  46. Stereoselective Epimerizations of Glycosyl Thiols

    Article • Organic Letters, October 2017, American Chemical Society (ACS)

    Paul Murphy

  47. Carbohydrate Chemistry

    Article • September 2017, Taylor & Francis

    Paul Murphy

  48. Allylic Azide Rearrangement in Tandem with Intramolecular Huisgen Cycloaddition for Iminosugar and Glycomimetic Synthesis: Functionalized Piperidine, Pyrrolidine, and Pyrrolotriazoles from d-Mannose

    Article • Synthesis, April 2017, Thieme Publishing Group

    Paul Murphy

  49. Methyl 2,3,6-tri-O-Benzoyl-4-O-(tert-butyldimethylsilyl)-β-d-galactopyranoside

    Article • Molbank, March 2017, MDPI AG

    Paul Murphy

  50. Isolation and synthesis of pygmanilines, phenylurea derivatives from the Northeastern Atlantic lichen Lichina pygmaea

    Article • Tetrahedron Letters, March 2017, Elsevier

    Paul Murphy

  51. Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design

    Article • Histochemistry and Cell Biology, December 2016, Springer Science + Business Media

    Paul Murphy

  52. Synthesis and Biological Evaluation of Migrastatin Macrotriazoles

    Article • European Journal of Organic Chemistry, December 2016, Wiley

    Professor Giulio Rastelli, Paul Murphy

  53. Synthesis of an Orthogonally Protected Polyhydroxylated Cyclopentene froml-Sorbose

    Article • Chemistry - An Asian Journal, July 2016, Wiley

    Dr Leigh Fon Jones, Paul Murphy

  54. Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric Recognition

    Article • Molecules, May 2016, MDPI AG

    Paul Murphy

  55. Coiled coil type neoglycoproteins presenting three lactose residues

    Article • Tetrahedron Letters, March 2016, Elsevier

    Paul Murphy

  56. Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer

    Article • Organic Letters, January 2016, American Chemical Society (ACS)

    Paul Murphy

  57. Allylic Azide Rearrangement in Tandem with Huisgen Cycloaddition for Stereoselective Annulation: Synthesis of C-Glycosyl Iminosugars

    Article • Organic Letters, December 2015, American Chemical Society (ACS)

    Paul Murphy

  58. Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context

    Article • Histochemistry and Cell Biology, November 2015, Springer Science + Business Media

    Paul Murphy

  59. Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring

    Article • Chemistry - A European Journal, November 2015, Wiley

    Dr Leigh Fon Jones, Paul Murphy

  60. Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity

    Article • Cell, October 2015, Elsevier

    Paul Murphy

  61. Glycoclusters as lectin inhibitors: comparative analysis on two plant agglutinins with different folding as a step towards rules for selectivity

    Article • Tetrahedron, September 2015, Elsevier

    Paul Murphy

  62. Decorated Macrocycles via Ring-Closing Double-Reductive Amination. Identification of an Apoptosis Inducer of Leukemic Cells That at Least Partially Antagonizes a 5-HT2 Receptor

    Article • Organic Letters, March 2015, American Chemical Society (ACS)

    Paul Murphy

  63. Lectins: Getting Familiar with Translators of the Sugar Code

    Article • Molecules, January 2015, MDPI AG

    Paul Murphy

  64. Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Paul Murphy

  65. Synthesis of Migrastatin and its Macroketone Analogue and In Vivo FRAP Analysis of the Macroketone on E‐Cadherin Dynamics

    Article • ChemBioChem, June 2014, Wiley

    Paul Murphy

  66. Combining glycocluster synthesis with protein engineering: an approach to probe into the significance of linker length in a tandem-repeat-type lectin (galectin-4)

    Article • Carbohydrate Research, May 2014, Elsevier

    Paul Murphy

  67. Synthesis of α-galactosyl ceramide analogues with an α-triazole at the anomeric carbon

    Article • Tetrahedron, May 2014, Elsevier

    Paul Murphy

  68. Synthesis of iminosugar derivatives presenting naphthyl and alkyl amine interacting groups and binding to somatostatin receptors

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Paul Murphy

  69. Migrastatin Analogues Inhibit Canine Mammary Cancer Cell Migration and Invasion

    Article • PLOS One, October 2013, PLOS

    Paul Murphy

  70. Regiospecific Anomerisation of Acylated Glycosyl Azides and Benzoylated Disaccharides by Using TiCl4

    Article • Chemistry - A European Journal, September 2013, Wiley

    Paul Murphy

  71. Synthesis of a-O- and a-S-Glycosphingolipids Related to Sphingomonous cell Wall Antigens Using Anomerisation

    Article • Molecules, September 2013, MDPI AG

    Paul Murphy

  72. Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint

    Article • Cell Cycle, May 2013, Taylor & Francis

    Paul Murphy

  73. The Third Dimension of Reading the Sugar Code by Lectins: Design of Glycoclusters with Cyclic Scaffolds as Tools with the Aim to Define Correlations between Spatial Presentation and Activity

    Article • Molecules, April 2013, MDPI AG

    Paul Murphy

  74. Lack of activation of UCP1 in isolated brown adipose tissue mitochondria by glucose-O-ω-modified saturated fatty acids of various chain lengths

    Article • Journal of Chemical Biology, March 2013, Springer Science + Business Media

    Paul Murphy

  75. Multivalent glycoconjugates as anti-pathogenic agents

    Article • Chemical Society Reviews, January 2013, Royal Society of Chemistry

    Francesco Sansone, Professor Alessandro Casnati, Professor Anna Bernardi, Paul Murphy

  76. Synthesis of bivalent glycoclusters containing GlcNAc as hexasaccharide mimetics. Bactericidal activity against Helicobacter pylori

    Article • Carbohydrate Research, October 2012, Elsevier

    Dr Marguerite Clyne, Paul Murphy

  77. Inhibition of Burkholderia multivorans Adhesion to Lung Epithelial Cells by Bivalent Lactosides

    Article • Molecules, August 2012, MDPI AG

    Paul Murphy

  78. Synthesis, kinase activity and molecular modeling of a resorcylic acid lactone incorporating an amide and a trans-enone in the macrocycle

    Article • Tetrahedron, July 2012, Elsevier

    Paul Murphy

  79. Bi- to tetravalent glycoclusters: synthesis, structure–activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Paul Murphy

  80. Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons

    Article • Bioorganic & Medicinal Chemistry Letters, January 2012, Elsevier

    Paul Murphy

  81. Synthesis of a Benzomacrolactone-Based Somatostatin Mimetic

    Article • Organic Letters, October 2011, American Chemical Society (ACS)

    Paul Murphy

  82. Synthesis of 1-Deoxynojirimycin Derivatives from L-Sorbose via Wittig Reactions

    Article • Journal of Carbohydrate Chemistry, September 2011, Taylor & Francis

    Paul Murphy

  83. Synthesis of α-S-Glycosphingolipids Based on Uronic Acids

    Article • Organic Letters, August 2011, American Chemical Society (ACS)

    Paul Murphy

  84. Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcylic acid lactone series and biological evaluation

    Article • Bioorganic & Medicinal Chemistry Letters, February 2011, Elsevier

    Paul Murphy

  85. Biological study of a somatostatin mimetic based on the 1-deoxynojrimycin scaffold

    Article • Bioorganic & Medicinal Chemistry Letters, January 2011, Elsevier

    Paul Murphy

  86. Towards echinomycin mimetics by grafting quinoxaline residues on glycophane scaffolds

    Article • Bioorganic & Medicinal Chemistry, January 2011, Elsevier

    Paul Murphy

  87. N-(8-(3-Ethynylphenoxy)octyl-1-deoxynojirimycin suppresses growth and migration of human lung cancer cells

    Article • Bioorganic & Medicinal Chemistry Letters, December 2010, Elsevier

    Paul Murphy

  88. Ultrasound-assisted synthesis of C-glycosides

    Article • Tetrahedron Letters, December 2010, Elsevier

    Paul Murphy

  89. Access to Resorcylic Acid Lactones via Phosphonate Based Intramolecular Olefination

    Article • The Journal of Organic Chemistry, October 2010, American Chemical Society (ACS)

    Paul Murphy

  90. Synthesis of congeners of migrastatin and dorrigocin A from d-xylose

    Article • Tetrahedron Letters, October 2010, Elsevier

    Paul Murphy

  91. SnCl4- and TiCl4-Catalyzed Anomerization of Acylated O- and S-Glycosides: Analysis of Factors That Lead to Higher α:β Anomer Ratios and Reaction Rates

    Article • The Journal of Organic Chemistry, September 2010, American Chemical Society (ACS)

    Paul Murphy

  92. Metathesis and Macrocycles with Embedded Carbohydrates

    Article • European Journal of Organic Chemistry, July 2010, Wiley

    Paul Murphy

  93. Biological study of the Angiogenesis Inhibitor N‐(8‐(3‐ethynylphenoxy)octyl‐1‐deoxynojirimycin

    Article • Chemical Biology & Drug Design, May 2010, Wiley

    Paul Murphy

  94. Synthesis of Bivalent Lactosides Based on Terephthalamide,N,N′-Diglucosylterephthalamide, and Glycophane Scaffolds and Assessment of Their Inhibitory Capacity on Medically Relevant Lectins

    Article • The Journal of Organic Chemistry, November 2009, American Chemical Society (ACS)

    Paul Murphy

  95. Synthesis of a constrained polyfunctional bicyclic iminocyclitol scaffold from l-sorbose via a tandem sequence including stereoselective intramolecular Huisgen cycloaddition

    Article • Tetrahedron Letters, August 2009, Elsevier

    Paul Murphy

  96. Glycotriazolophane Synthesis via Click Chemistry

    Article • Synlett, July 2009, Thieme Publishing Group

    Paul Murphy

  97. α-Glycosphingolipids via Chelation-Induced Anomerization of O- and S-Glucuronic and Galacturonic Acid Derivatives

    Article • Organic Letters, January 2009, American Chemical Society (ACS)

    Paul Murphy

  98. Synthesis of a Novel Polyhydroxylated Salicylic Acid Lactone Framework

    Article • Organic Letters, January 2009, American Chemical Society (ACS)

    Paul Murphy

  99. Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Paul Murphy

  100. Synthesis of novel glycophanes derived from glucuronic acid by ring closing alkene and alkyne metathesis

    Article • Carbohydrate Research, October 2008, Elsevier

    Paul Murphy

  101. New Access to 1-Deoxynojirimycin Derivatives via Azide−Alkene Cycloaddition

    Article • Organic Letters, August 2008, American Chemical Society (ACS)

    Paul Murphy

  102. Synthesis of Somatostatin Mimetics Based on 1‐Deoxynojirimycin

    Article • ChemMedChem, July 2008, Wiley

    Paul Murphy

  103. Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis

    Article • Bioorganic & Medicinal Chemistry, June 2008, Elsevier

    Paul Murphy

  104. Synthesis of Novel Macrolactam and Macroketone Analogues of Migrastatin from D‐Glucal and Comparison with Macrolactone and Acyclic Analogues: A Dorrigocin A Congener Is a Potent Inhibitor of Gastric Cancer Cell Migration

    Article • European Journal of Organic Chemistry, March 2008, Wiley

    Paul Murphy

  105. Corrigendum to “Synthesis of sugar-lactams from azides of glucuronic acid”

    Article • Carbohydrate Research, February 2008, Elsevier

    Paul Murphy

  106. Hybrid angiogenesis inhibitors: Synthesis and biological evaluation of bifunctional compounds based on 1-deoxynojirimycin and aryl-1,2,3-triazoles

    Article • Bioorganic & Medicinal Chemistry Letters, February 2008, Elsevier

    Paul Murphy

  107. Synthesis of Novel Migrastatin and Dorrigocin A Analogues from D‐Glucal

    Article • Chemistry - A European Journal, February 2008, Wiley

    Paul Murphy

  108. Synthesis of sugar-lactams from azides of glucuronic acid

    Article • Carbohydrate Research, September 2007, Elsevier

    Paul Murphy

  109. Peptidomimetics, Glycomimetics and Scaffolds from Carbohydrate Building Blocks

    Article • European Journal of Organic Chemistry, August 2007, Wiley

    Paul Murphy

  110. Selective protecting group manipulations on the 1-deoxynojirimycin scaffold

    Article • Tetrahedron, July 2007, Elsevier

    Paul Murphy

  111. Synthesis of Macrolide−Saccharide Hybrids by Ring-Closing Metathesis of Precursors Derived from Glycitols and Benzoic Acids

    Article • The Journal of Organic Chemistry, February 2007, American Chemical Society (ACS)

    Paul Murphy

  112. Glycosidation–Anomerisation Reactions of 6,1‐Anhydroglucopyranuronic Acid and Anomerisation of β‐D‐Glucopyranosiduronic Acids Promoted by SnCl4

    Article • Chemistry - A European Journal, January 2007, Wiley

    Paul Murphy

  113. The synthesis of cyclic imidates from amides of glucuronic acid and investigation of glycosidation reactions

    Article • Carbohydrate Research, January 2007, Elsevier

    Paul Murphy

  114. Syntheses of Peptidomimetics Based on Pyranose and Polyhydroxylated Piperidine Scaffolds

    Article • Current Organic Synthesis, November 2006, Bentham Science Publishers

    Paul Murphy

  115. N-Glycosyl-thiophene-2-carboxamides: synthesis, structure and effects on the growth of diverse cell types

    Article • Carbohydrate Research, July 2006, Elsevier

    Paul Murphy

  116. N-Glycosyl-thiophene-2-carboxamides: Effects on endothelial cell growth in the presence and absence of bFGF—A significant increase in potency using per-O-acetylated sugar analogues

    Article • Bioorganic & Medicinal Chemistry Letters, March 2006, Elsevier

    Paul Murphy

  117. Symbiosis in chemistry and biology

    Article • Nature Chemical Biology, February 2006, Springer Science + Business Media

    Professor Peter Rutledge, Paul Murphy

  118. On the Mechanism of Mitochondrial Uncoupling Protein 1 Function

    Article • Journal of Biological Chemistry, January 2006, Elsevier

    Paul Murphy

  119. Synthesis of Somatostatin Mimetics Based on the 1-Deoxymannojirimycin Scaffold

    Article • The Journal of Organic Chemistry, September 2005, American Chemical Society (ACS)

    Paul Murphy

  120. Synthesis of a glycolipid for studying mechanisms of mitochondrial uncoupling proteins

    Article • Carbohydrate Research, June 2005, Elsevier

    Paul Murphy

  121. Novel Synthesis of Castanospermine and 1-Epicastanospermine

    Article • Organic Letters, May 2005, American Chemical Society (ACS)

    Paul Murphy

  122. The crystal structure of a cyclic glycolipid reveals a carbohydrate–carbohydrate interaction interface

    Article • Carbohydrate Research, May 2005, Elsevier

    Paul Murphy

  123. Synthesis and Structural Analysis of the Anilides of Glucuronic Acid and Orientation of the Groups on the Carbohydrate Scaffolding

    Article • The Journal of Organic Chemistry, April 2005, American Chemical Society (ACS)

    Paul Murphy

  124. Synthesis of Structurally Defined Scaffolds for Bivalent Ligand Display Based on Glucuronic Acid Anilides. The Degree of Tertiary Amide Isomerism and Folding Depends on the Configuration of a Glycosyl Azide

    Article • The Journal of Organic Chemistry, April 2005, American Chemical Society (ACS)

    Paul Murphy

  125. A study of the effects of subunit pre-orientation for diarylpyrrole esters; design of new aryl-heteroaryl fluorescent sensors

    Article • New Journal of Chemistry, January 2005, Royal Society of Chemistry

    Paul Murphy

  126. Synthesis and conformational analysis of novel water soluble macrocycles incorporating carbohydrates, including a β-cyclodextrin mimic

    Article • Tetrahedron Asymmetry, January 2005, Elsevier

    Paul Murphy

  127. Synthesis of Structurally Diverse and Defined Bivalent Mannosides on Saccharide Scaffolding

    Article • Organic Letters, December 2004, American Chemical Society (ACS)

    Paul Murphy

  128. Metathesis of Structurally Preorganized Bivalent Carbohydrates. Synthesis of Macrocyclic and Oligomeric Scaffolds

    Article • Organic Letters, October 2004, American Chemical Society (ACS)

    Paul Murphy

  129. Synthesis of disaccharides derived from heparin and evaluation of effects on endothelial cell growth and on binding of heparin to FGF-2

    Article • Carbohydrate Research, October 2004, Elsevier

    Paul Murphy

  130. Conformational Effects on Glycoside Reactivity:  Study of the High Reactive Conformer of Glucose

    Article • Journal of the American Chemical Society, September 2004, American Chemical Society (ACS)

    Paul Murphy

  131. Synthesis of a glucuronic acid and glucose conjugate library and evaluation of effects on endothelial cell growth

    Article • Carbohydrate Research, August 2004, Elsevier

    Paul Murphy

  132. Synthesis of peptidomimetics based on iminosugar and β-d-glucopyranoside scaffolds and inhibiton of HIV-protease

    Article • Tetrahedron, July 2004, Elsevier

    Paul Murphy

  133. Glycosidation Reactions of Silyl Ethers with Conformationally Inverted Donors Derived from Glucuronic Acid: Stereoselective Synthesis of Glycosides and 2‐Deoxyglycosides

    Article • Angewandte Chemie, April 2004, Wiley

    Paul Murphy

  134. A General Synthesis of Iminosugars

    Article • The Journal of Organic Chemistry, April 2004, American Chemical Society (ACS)

    Paul Murphy

  135. Synthesis of an iminosugar based peptidomimetic analogue

    Article • Tetrahedron Letters, March 2004, Elsevier

    Paul Murphy

  136. Synthesis and X-ray single crystal structure of a bivalent glycocluster

    Article • Chemical Communications, January 2004, Royal Society of Chemistry

    Paul Murphy

  137. Development of Carbohydrate-Based Scaffolds for Restricted Presentation of Recognition Groups. Extension to Divalent Ligands and Implications for the Structure of Dimerized Receptors

    Article • The Journal of Organic Chemistry, June 2003, American Chemical Society (ACS)

    Paul Murphy

  138. Synthesis of novel HIV-1 protease inhibitors based on carbohydrate scaffolds

    Article • Tetrahedron, March 2003, Elsevier

    Paul Murphy

  139. Confirmation of the structure of a glucono-1,4-lactone derivative obtained from silylation of glucono-1,5-lactone

    Article • Tetrahedron Asymmetry, January 2003, Elsevier

    Paul Murphy

  140. Identification of novel inhibitors of fibroblast growth factor (FGF-2) binding to heparin and endothelial cell survival from a structurally diverse carbohybrid library

    Article • Bioorganic & Medicinal Chemistry Letters, November 2002, Elsevier

    Paul Murphy

  141. Synthesis of α-Glucuronic Acid and Amide Derivatives in the Presence of a Participating 2-Acyl Protecting Group

    Article • Organic Letters, September 2002, American Chemical Society (ACS)

    Paul Murphy

  142. Structure-based design and synthesis of HIV-1 protease inhibitors employing β-d-mannopyranoside scaffolds

    Article • Bioorganic & Medicinal Chemistry Letters, July 2002, Elsevier

    Paul Murphy

  143. A Study of the Epoxidation of 6-Deoxyhex-5-enopyranosides. 1,5-Dicarbonyl Derivatives and Novel Synthetic Routes to d-xylo-Hexos-5-ulose and d-lyxo-Hexos-5-ulose

    Article • The Journal of Organic Chemistry, April 2002, American Chemical Society (ACS)

    Paul Murphy

  144. A New Route toexo-Glycals Using the Ramberg−Bäcklund Rearrangement

    Article • European Journal of Organic Chemistry, April 2002, Wiley

    Paul Murphy

  145. Novel Synthesis of the Glycosidase Inhibitor Deoxymannojirimycin and of a Synthetic Precursor d-lyxo-Hexos-5-ulose

    Article • Organic Letters, September 2001, American Chemical Society (ACS)

    Paul Murphy

  146. Stereospecific synthesis of β-d-allopyranosides by dihydroxylation of β-d-erythro-2,3-dideoxyhex-2-enopyranosides

    Article • Carbohydrate Research, September 2001, Elsevier

    Paul Murphy

  147. Application of Ugi Reactions in Synthesis of Divalent Neoglycoconjugates:  Evidence That the Sugars Are Presented in Restricted Conformation

    Article • Organic Letters, August 2001, American Chemical Society (ACS)

    Paul Murphy

  148. Synthesis of d-Hexos-5-uloses by Novel in Situ Hydrolysis of Epoxides Derived from 6-Deoxyhex-5-enopyranosides

    Article • Organic Letters, November 2000, American Chemical Society (ACS)

    Paul Murphy

  149. The reactions of diazo compounds with lactones. Part 2.† The reaction of cyclic 2-diazo-1,3-dicarbonyl compounds with diketene: benzofuran formation

    Article • Journal of the Chemical Society Perkin Transactions 1, January 2000, Royal Society of Chemistry

    Paul Murphy

  150. The reactions of diazo compounds with lactones. Part 1. Cyclopropanespiro-β-lactones from diketene: synthesis and reactions

    Article • Journal of the Chemical Society Perkin Transactions 1, January 2000, Royal Society of Chemistry

    Paul Murphy

  151. The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewisx

    Article • Bioorganic & Medicinal Chemistry, December 1998, Elsevier

    Paul Murphy

  152. A Ramberg-Bäcklund approach to exo-glycals

    Article • Tetrahedron Letters, October 1998, Elsevier

    Paul Murphy

  153. The synthesis of novel structural analogues of sialyl Lewisx

    Article • Tetrahedron Letters, May 1998, Elsevier

    Paul Murphy

  154. Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    Paul Murphy

  155. Glycosylation reactions of 2,3,4-tri-O-chlorosulfonyl-β-l-fucopyranosyl chloride and 2,3,4-tri-O-chlorosulfonyl-β-d-xylopyranosyl chloride

    Article • Carbohydrate Research, June 1996, Elsevier

    Paul Murphy

  156. Metal catalysed rearrangement of cyclopropanespiro-β-lactones to 2-furanones

    Article • Tetrahedron Letters, September 1994, Elsevier

    Paul Murphy

  157. Lewis acid promoted anomerisation: recent developments and applications

    Article • Royal Society of Chemistry

    Paul Murphy