All Stories

  1. Ibrutinib significantly inhibited Bruton’s tyrosine kinase (BTK) phosphorylation,in-vitro proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model

    Article • OncoImmunology, October 2018, Taylor & Francis

    Yaya Chu, Dr Paul J Galardy

  2. Keeping an Open Mind: Cognitive Bias in the Evaluation of an Infant with Posterior-Lateral Rib Fractures

    Article • Case Reports in Pediatrics, January 2017, Hindawi Publishing Corporation

    Dr Paul J Galardy

  3. Congenital Amegakaryocytic Thrombocytopenia

    Article • Journal of Pediatric Hematology/Oncology, May 2015, Wolters Kluwer Health

    Dr Paul J Galardy

  4. Rituximab with chemotherapy in children and adolescents with central nervous system and/or bone marrow-positive Burkitt lymphoma/leukaemia: a Children's Oncology Group Report

    Article • British Journal of Haematology, July 2014, Wiley

    Dr Paul J Galardy

  5. Childhood and Adolescent B-Cell Lymphoma: Bench to Bedside and Back to Bench

    Article • March 2014, World Scientific Pub Co Pte Lt

    Dr Paul J Galardy

  6. Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B-NHL: a Children's Oncology Group Report

    Article • British Journal of Haematology, September 2013, Wiley

    Dr Paul J Galardy

  7. Bone Marrow Failure: Congenital Amegakaryocytic Thrombocytopenia - A Case Report of Successful Matched Unrelated Bone Marrow Transplantation in Pediatric Twins

    Article • Biology of Blood and Marrow Transplantation, February 2013, Elsevier

    Dr Paul J Galardy

  8. Ubiquitin Hydrolase UCH-L1 Destabilizes mTOR Complex 1 by Antagonizing DDB1-CUL4-Mediated Ubiquitination of Raptor

    Article • Molecular and Cellular Biology, January 2013, ASM Journals

    Dr Paul J Galardy

  9. USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis

    Article • Journal of Clinical Investigation, November 2012, American Society for Clinical Investigation

    Dr Paul J Galardy

  10. Overexpression of Ubiquitin Specific Protease 44 (USP44) Induces Chromosomal Instability and Is Frequently Observed in Human T-Cell Leukemia

    Article • PLoS ONE, August 2011, PLOS

    Dr Paul J Galardy

  11. Rituximab in combination with multiagent chemotherapy for Pediatric follicular lymphoma

    Article • Pediatric Blood & Cancer, April 2011, Wiley

    Dr Paul J Galardy

  12. The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling

    Article • Leukemia, June 2010, Springer Science + Business Media

    Dr Paul J Galardy

  13. DUBs and cancer: The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors

    Article • Cell Cycle, June 2009, Taylor & Francis

    Dr Paul J Galardy

  14. Screen for ISG15-crossreactive Deubiquitinases

    Article • PLoS ONE, July 2007, PLOS

    Dr Paul J Galardy

  15. Disorders of Coagulation and Thrombosis

    Article • January 2007, Elsevier

    Dr Paul J Galardy

  16. Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib*

    Article • British Journal of Haematology, July 2006, Wiley

    Dr Paul J Galardy

  17. Regulation of monoubiquitinated PCNA by DUB autocleavage

    Article • Nature Cell Biology, March 2006, Springer Science + Business Media

    Dr Paul J Galardy

  18. Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib

    Article • Nature Methods, April 2005, Nature

    Dr Paul J Galardy

  19. Mechanism‐Based Proteomics Tools Based on Ubiquitin and Ubiquitin‐Like Proteins: Crystallography, Activity Profiling, and Protease Identification

    Article • January 2005, Elsevier

    Dr Paul J Galardy

  20. Mechanism‐Based Proteomics Tools Based on Ubiquitin and Ubiquitin‐Like Proteins: Synthesis of Active Site‐Directed Probes

    Article • January 2005, Elsevier

    Dr Paul J Galardy

  21. Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate

    Article • Journal of Biological Chemistry, November 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Paul J Galardy, Rachelle Gaudet

  22. Chemistry-Based Functional Proteomics:  Mechanism-Based Activity-Profiling Tools for Ubiquitin and Ubiquitin-like Specific Proteases

    Article • Journal of Proteome Research, April 2004, American Chemical Society (ACS)

    Dr Paul J Galardy

  23. Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

    Article • Proceedings of the National Academy of Sciences, February 2004, Proceedings of the National Academy of Sciences

    Dr Paul J Galardy

  24. Chemistry in Living Cells: Detection of Active Proteasomes by a Two-Step Labeling Strategy

    Article • Angewandte Chemie, August 2003, Wiley

    Dr Paul J Galardy

  25. Chemistry in Living Cells: Detection of Active Proteasomes by a Two-Step Labeling Strategy

    Article • Angewandte Chemie International Edition, August 2003, Wiley

    Dr Paul J Galardy