All Stories

  1. Enzyme Kinetics and High-Throughput Screening for Biocatalysis and Diagnostics

    Article • Current Biotechnology, July 2015, Bentham Science Publishers

    Professor Paul C Engel

  2. Editorial (Thematic Issue): Enzymes for Biotechnology

    Article • Current Biotechnology, July 2015, Bentham Science Publishers

    Professor Paul C Engel

  3. Halophilic Enzymes: Characteristics, Structural Adaptation and Potential Applications for Biocatalysis

    Article • Current Biotechnology, December 2013, Bentham Science Publishers

    Professor Paul C Engel

  4. Amino acid amino transferase mechanism affects potential for biocatalysis

    Article • FEBS Journal, December 2013, Wiley

    Professor Paul C Engel

  5. Halophilic enzymes: characteristics, structural adaptation and potential applications for biocatalysis

    Article • Current Biotechnology, September 2013, Bentham Science Publishers

    Professor Paul C Engel

  6. Structure of NADP+‐dependent glutamate dehydrogenase from Escherichia coli – reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases

    Article • FEBS Journal, August 2013, Wiley

    Professor Paul C Engel

  7. Glutamate Dehydrogenases: The Why and How of Coenzyme Specificity

    Article • Neurochemical Research, June 2013, Springer Science + Business Media

    Professor Paul C Engel

  8. Development of a satisfactory and general continuous assay for aminotransferases by coupling with (R)-2-hydroxyglutarate dehydrogenase

    Article • Analytical Biochemistry, December 2012, Elsevier

    Professor Paul C Engel

  9. Prospects for robust biocatalysis: engineering of novel specificity in a halophilic amino acid dehydrogenase

    Article • Extremophiles, October 2012, Springer Science + Business Media

    Professor Paul C Engel

  10. Reversal of the extreme coenzyme selectivity of Clostridium symbiosum glutamate dehydrogenase

    Article • FEBS Journal, July 2012, Wiley

    Professor Paul C Engel

  11. Overexpression in a non-native halophilic host and biotechnological potential of NAD+-dependent glutamate dehydrogenase from Halobacterium salinarum strain NRC-36014

    Article • Extremophiles, April 2012, Springer Science + Business Media

    Professor Paul C Engel

  12. Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity

    Article • Journal of Structural Biology, February 2012, Elsevier

    Professor Paul C Engel

  13. Molecular recruitment as a basis for negative dominant inheritance? Propagation of misfolding in oligomers of IMPDH1, the mutated enzyme in the RP10 form of retinitis pigmentosa

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, November 2011, Elsevier

    Professor Paul C Engel

  14. A marriage full of surprises; forty-five years living with glutamate dehydrogenase

    Article • Neurochemistry International, September 2011, Elsevier

    Professor Paul C Engel

  15. An Examination by Site-Directed Mutagenesis of Putative Key Residues in the Determination of Coenzyme Specificity in ClostridialNAD...

    Article • Enzyme Research, August 2011, Hindawi Publishing Corporation

    Professor Paul C Engel

  16. Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

    Article • Malaria Journal, July 2011, Springer Science + Business Media

    Professor Paul C Engel

  17. Re‐engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild‐type enzyme

    Article • FEBS Journal, May 2011, Wiley

    Professor Paul C Engel

  18. Kinetic characterisation of recombinant Corynebacterium glutamicum NAD+-dependent LDH over-expressed in E. coli and its rescue of an lldD − phenotype in C. glutamicum: the issue of reversibility re-examined

    Article • Archives of Microbiology, May 2011, Springer Science + Business Media

    Professor Paul C Engel

  19. Making biochemistry count: life among the amino acid dehydrogenases

    Article • Biochemical Society Transactions, April 2011, Portland Press Ltd.

    Professor Paul C Engel

  20. Forced evolution ofEscherichia colicells with the ability to effectively utilize non-natural amino acidsl-tert-leucine,l-norleucine and γ-methyl-l-leucine

    Article • Biocatalysis and Biotransformation, November 2010, Taylor & Francis

    Professor Paul C Engel

  21. Susceptibility of Plasmodium falciparum to glutamate dehydrogenase inhibitors—A possible new antimalarial target

    Article • Molecular and Biochemical Parasitology, August 2010, Elsevier

    Professor Paul C Engel

  22. The –SH Protection Method for Determining Accurate Kd Values for Enzyme-Coenzyme Complexes of NAD+-Dependent Glutamate Dehydrogenase and Engineered Mutants: Evidence for Nonproductive NADPH Complexes

    Article • Enzyme Research, June 2010, Hindawi Publishing Corporation

    Professor Paul C Engel

  23. Crystallization and preliminary structural analyses of glutamate dehydrogenase fromPeptoniphilus asaccharolyticus

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2010, International Union of Crystallography

    Professor Paul C Engel

  24. An NSAID-like Compound, FT-9, Preferentially Inhibits γ-Secretase Cleavage of the Amyloid Precursor Protein Compared to Its Effect on Amyloid Precursor-like Protein 1

    Article • Biochemistry, October 2009, American Chemical Society (ACS)

    Professor Paul C Engel

  25. Clinical mutants of human glucose 6-phosphate dehydrogenase: Impairment of NADP+ binding affects both folding and stability

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2009, Elsevier

    Professor Paul C Engel

  26. Efficient screening for new amino acid dehydrogenase activity: Directed evolution of Bacillus sphaericus phenylalanine dehydrogenase towards activity with an unsaturated non-natural amino acid

    Article • Journal of Biotechnology, June 2009, Elsevier

    Professor Paul C Engel

  27. Modular coenzyme specificity: A domain‐swopped chimera of glutamate dehydrogenase

    Article • Proteins Structure Function and Bioinformatics, May 2009, Wiley

    Professor Paul C Engel

  28. An optimised system for refolding of human glucose 6-phosphate dehydrogenase

    Article • BMC Biotechnology, January 2009, Springer Science + Business Media

    Professor Paul C Engel

  29. The structural basis of proteolytic activation of bovine glutamate dehydrogenase

    Article • Protein Science, August 2008, Wiley

    Professor Paul C Engel

  30. What is the role of the second “structural” NADP+‐binding site in human glucose 6‐phosphate dehydrogenase?

    Article • Protein Science, August 2008, Wiley

    Professor Paul C Engel

  31. Homotropic allosteric control in clostridial glutamate dehydrogenase: Different mechanisms for glutamate and NAD+?

    Article • FEBS Letters, May 2008, Wiley

    Professor Paul C Engel

  32. Apparent negative co-operativity and substrate inhibition in overexpressed glutamate dehydrogenase from Escherichia coli

    Article • FEMS Microbiology Letters, April 2008, Oxford University Press (OUP)

    Professor Paul C Engel

  33. D-amino acids from racemic mixtures: quantitative enzymatic removal of L-enantiomer

    Article • Organic & Biomolecular Chemistry, January 2008, Royal Society of Chemistry

    Professor Paul C Engel

  34. Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase variants, G6PDPlymouth and G6PDMahidol: Evidence for defective protein folding as the basis of disease

    Article • Molecular Genetics and Metabolism, January 2008, Elsevier

    Professor Paul C Engel

  35. Enhancing long-term thermal stability in mesophilic glutamate dehydrogenase from Clostridium symbiosum by eliminating cysteine residues

    Article • Enzyme and Microbial Technology, November 2007, Elsevier

    Professor Paul C Engel

  36. Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site‐directed mutagenesis

    Article • FEBS Journal, September 2007, Wiley

    Professor Paul C Engel

  37. Cooperativity of GDH from Clostridium symbiosum at neutral pH

    Article • Journal of Biotechnology, September 2007, Elsevier

    Professor Paul C Engel

  38. Alteration of substrate specificity of phenylalanine dehydrogenase from Bacillus sphaericus towards an aliphatic unsaturated amino acid by directed evolution

    Article • Journal of Biotechnology, September 2007, Elsevier

    Professor Paul C Engel

  39. Re-activation of GDH(s) from Halobacterium salinarum, cloned and overexpressed in Escherichia coli

    Article • Journal of Biotechnology, September 2007, Elsevier

    Professor Paul C Engel

  40. The contribution of tryptophan residues to conformational changes in clostridial glutamate dehydrogenase − W64 and W449 as mediators of the cooperative response to glutamate

    Article • FEBS Journal, July 2007, Wiley

    Professor Paul C Engel

  41. Mutants of Phenylalanine Dehydrogenase: New Biocatalysts in the Asymmetric Synthesis and Racemic Resolution of Non‐Natural Amino Acids

    Article • ChemInform, June 2007, Wiley

    Professor Paul C Engel

  42. An engineered mutant, L307V of phenylalanine dehydrogenase from Bacillus sphaericus: high activity and stability in organic-aqueous solvent mixtures and utility for synthesis of non-natural l-amino acids

    Article • Enzyme and Microbial Technology, April 2007, Elsevier

    Professor Paul C Engel

  43. Functional properties of two mutants of human glucose 6-phosphate dehydrogenase, R393G and R393H, corresponding to the clinical variants G6PD Wisconsin and Nashville

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2006, Elsevier

    Professor Paul C Engel

  44. Marked decrease in specific activity contributes to disease phenotype in two human glucose 6-phosphate dehydrogenase mutants, G6PDUnionand G6PDAndalus

    Article • Human Mutation, September 2005, Hindawi Publishing Corporation

    Professor Paul C Engel

  45. Two novel variants of human medium chain acyl‐CoA dehydrogenase (MCAD)

    Article • FEBS Journal, August 2005, Wiley

    Professor Paul C Engel

  46. Identification of the residue responsible for catalysing regeneration of activity in the inactive glutamate dehydrogenase mutant D165N

    Article • FEBS Letters, April 2005, Wiley

    Professor Paul C Engel

  47. The discovery of four distinct glutamate dehydrogenase genes in a strain of Halobacterium salinarum

    Article • Gene, April 2005, Elsevier

    Professor Paul C Engel

  48. Properties of the thermostable glutamate dehydrogenase of the mesophilic anaerobe Peptostreptoccus asaccharolyticus purified by a novel method after over-expression in an Escherichia coli host

    Article • FEMS Microbiology Letters, March 2005, Oxford University Press (OUP)

    Professor Paul C Engel

  49. Spontaneous Chemical Reversion of an Active Site Mutation:  Deamidation of an Asparagine Residue Replacing the Catalytic Aspartic Acid of Glutamate Dehydrogenase

    Article • Biochemistry, February 2005, American Chemical Society (ACS)

    Professor Paul C Engel

  50. Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Professor Paul C Engel, Andrea Gualandi

  51. Enantioselective Synthesis of Non‐Natural Amino Acids Using Phenylalanine Dehydrogenases Modified by Site‐Directed Mutagenesis.

    Article • ChemInform, December 2004, Wiley

    Professor Paul C Engel

  52. The Y42H mutation in medium‐chain acyl‐CoA dehydrogenase, which is prevalent in babies identified by MS/MS‐based newborn screening, is temperature sensitive

    Article • European Journal of Biochemistry, September 2004, Wiley

    Professor Paul C Engel

  53. Novel nicotinamide adenine dinucleotide analogues as selective inhibitors of NAD+-dependent enzymes

    Article • Tetrahedron, July 2004, Elsevier

    Professor Paul C Engel

  54. Enantioselective synthesis of non-natural amino acids using phenylalanine dehydrogenases modified by site-directed mutagenesis

    Article • Organic & Biomolecular Chemistry, January 2004, Royal Society of Chemistry

    Professor Paul C Engel

  55. Kinetic analysis of phenylalanine dehydrogenase mutants designed for aliphatic amino acid dehydrogenase activity with guidance from homology‐based modelling

    Article • European Journal of Biochemistry, November 2003, Wiley

    Professor Paul C Engel

  56. Single Amino Acid Substitution in Bacillus sphaericus Phenylalanine Dehydrogenase Dramatically Increases Its Discrimination between Phenylalanine and Tyrosine Substrates

    Article • Biochemistry, August 2002, American Chemical Society (ACS)

    Professor Paul C Engel

  57. Recombinant human glucose‐6‐phosphate dehydrogenase

    Article • European Journal of Biochemistry, June 2002, Wiley

    Professor Paul C Engel

  58. Glutamate dehydrogenase of Halobacterium salinarum : evidence that the gene sequence currently assigned to the NADP + -dependent enzyme is in fact that of the NAD + -dependent glutamate dehydrogenase

    Article • FEMS Microbiology Letters, May 2002, Oxford University Press (OUP)

    Professor Paul C Engel, Professor MARIA-JOSE BONETE

  59. Formation of a Human “Electron Transferring Flavoprotein”

    Article • January 2002, Springer Science + Business Media

    Professor Paul C Engel

  60. Allosteric behaviour of 1:5 hybrids of mutant subunits of Clostridium symbiosum glutamate dehydrogenase differing in their amino acid specificity

    Article • Biochemical Journal, December 2001, Portland Press Ltd.

    Professor Paul C Engel

  61. Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site‐directed mutagenesis

    Article • European Journal of Biochemistry, November 2001, Wiley

    Professor Paul C Engel

  62. Purification and characterisation of a serine peptidase from the marine psychrophile strain PA-43

    Article • FEMS Microbiology Letters, July 2001, Oxford University Press (OUP)

    Professor Paul C Engel

  63. Medium-Chain Acyl-CoA Dehydrogenase (MCAD) Mutations Identified by MS/MS-Based Prospective Screening of Newborns Differ from Those Observed in Patients with Clinical Symptoms: Identification and Characterization of a New, Prevalent Mutation That Result...

    Article • The American Journal of Human Genetics, June 2001, Elsevier

    Professor Paul C Engel

  64. Construction, separation and properties of hybrid hexamers of glutamate dehydrogenase in which five of the six subunits are contributed by the catalytically inert D165S

    Article • European Journal of Biochemistry, March 2001, Wiley

    Professor Paul C Engel

  65. Contribution of an aspartate residue, D114, in the active site of clostridial glutamate dehydrogenase to the enzyme’s unusual pH dependence

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, January 2001, Elsevier

    Professor Paul C Engel

  66. A tale of terminology

    Article • Trends in Biochemical Sciences, September 2000, Elsevier

    Professor Paul C Engel

  67. Preliminary evidence for the existence of specific functional assemblies between enzymes of the β-oxidation pathway and the respiratory chain

    Article • Biochemical Journal, February 2000, Portland Press Ltd.

    Professor Paul C Engel

  68. Fluoride reactivates D165S glutamate dehydrogenase.

    Article • Biochemical Journal, June 1999, Portland Press Ltd.

    Professor Paul C Engel

  69. Specificity of coenzyme analogues and fragments in promoting or impeding the refolding of clostridial glutamate dehydrogenase

    Article • Protein Science, January 1999, Wiley

    Professor Paul C Engel

  70. 5,5′-Dithiobis-(2-Nitrobenzoic Acid) as a Probe for a Non-Essential Cysteine Residue at the Medium Chain Acyl-Coenzyme a Dehydrogenase Binding Site of the Human ‘Electron Transferring Flavoprotein’ (ETF)

    Article • Journal of Enzyme Inhibition, January 1999, Taylor & Francis

    Professor Paul C Engel

  71. Insights into the mechanism of domain closure and substrate specificity of glutamate dehydrogenase from Clostridium symbiosum 1 1Edited by A. R. Fersht

    Article • Journal of Molecular Biology, January 1999, Elsevier

    Professor Paul C Engel

  72. Protein thermostability in extremophiles

    Article • Biochimie, November 1998, Elsevier

    Professor Paul C Engel

  73. An inhibitor to target MCAD

    Article • FEBS Letters, October 1998, Wiley

    Professor Paul C Engel

  74. A monomeric mutant of Clostridium symbiosum glutamate dehydrogenase: Comparison with a structured monomeric intermediate obtained during refolding

    Article • Protein Science, April 1998, Wiley

    Professor Paul C Engel

  75. Intersubunit Communication in Hybrid Hexamers of K89L/A163G/S380A and C320S Mutants of Glutamate Dehydrogenase fromClostridium symbiosum

    Article • Biochemistry, December 1997, American Chemical Society (ACS)

    Professor Paul C Engel

  76. Determinants of Substrate Specificity in the Superfamily of Amino Acid Dehydrogenases,

    Article • Biochemistry, December 1997, American Chemical Society (ACS)

    Professor Paul C Engel

  77. Kinetic studies on the binding of 1,N6-etheno-NAD+ to glutamate dehydrogenase from Clostridium symbiosum

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, June 1997, Elsevier

    Professor Paul C Engel

  78. GDH dimers

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, October 1996, Elsevier

    Professor Paul C Engel

  79. The Mechanism of Substrate and Coenzyme Binding to Clostridial Glutamate Dehydrogenase During Reductive Amination

    Article • European Journal of Biochemistry, December 1995, Wiley

    Professor Paul C Engel

  80. Dramatic cooperativity in clostridial glutamate dehydrogenase

    Article • Biochemistry, September 1995, American Chemical Society (ACS)

    Professor Paul C Engel

  81. Homology-based mutagenesis of an amino acid dehydrogenase

    Article • FEBS Letters, August 1995, Wiley

    Professor Paul C Engel

  82. Insights into Thermal Stability from a Comparison of the Glutamate Dehydrogenases from Pyrococcus furiosus and Thermococcus litoralis

    Article • European Journal of Biochemistry, May 1995, Wiley

    Professor Paul C Engel

  83. Insights into Thermal Stability from a Comparison of the Glutamate Dehydrogenases from Pyrococcus furiosus and Thermococcus litoralis

    Article • European Journal of Biochemistry, May 1995, Wiley

    Professor Paul C Engel

  84. Correlation of intron-exon organisation with the three-dimensional structure in glutamate dehydrogenase

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, March 1995, Elsevier

    Professor Paul C Engel

  85. Changing substrate specificity in a bacterial GDH

    Article • Protein Engineering Design and Selection, January 1995, Oxford University Press (OUP)

    Professor Paul C Engel

  86. Clostridial GDH forms an E-DTNB complex before reacting.

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, December 1994, Elsevier

    Professor Paul C Engel

  87. 'Essential' -SH in clostridial GDH is not truly essential.

    Article • Protein Engineering Design and Selection, January 1994, Oxford University Press (OUP)

    Professor Paul C Engel

  88. Evolution of Substrate Diversity in the Superfamily of Amino Acid Dehydrogenases

    Article • Journal of Molecular Biology, December 1993, Elsevier

    Professor Paul C Engel

  89. Crystallization of the NADP+-dependent Glutamate Dehydrogenase from Escherichia coli

    Article • Journal of Molecular Biology, December 1993, Elsevier

    Professor Paul C Engel

  90. The mechanism of substrate and coenzyme binding to clostridial glutamate dehydrogenase during oxidative deamination

    Article • European Journal of Biochemistry, May 1993, Wiley

    Professor Paul C Engel

  91. The essentail active‐site lysines of clostridial glutamate dehydrogenase

    Article • European Journal of Biochemistry, July 1992, Wiley

    Professor Paul C Engel

  92. The glutamate dehydrogenase gene of Clotridium symbiosum

    Article • European Journal of Biochemistry, May 1992, Wiley

    Professor Paul C Engel

  93. Subunit assembly and active site location in the structure of glutamate dehydrogenase

    Article • Proteins Structure Function and Bioinformatics, January 1992, Wiley

    Professor Paul C Engel

  94. Functional studies of a glutamate dehydrogenase with known three-dimensional structure: steady-state kinetics of the forward and reverse reactions catalysed by the NAD+-dependent glutamate dehydrogenase of Clostridium symbiosum

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, December 1991, Elsevier

    Professor Paul C Engel

  95. Specific diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in dried blood spots by a polymerase chain reaction (PCR) assay detecting a point-mutation (G985) in the MCAD gene

    Article • Clinica Chimica Acta, November 1991, Elsevier

    Professor Paul C Engel

  96. The partial amino acid sequence of the NAD -dependent glutamate dehydrogenase of Clostridium symbiosum: implications for the evolution and structural basis of coenzyme specificity

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, November 1991, Elsevier

    Professor Paul C Engel

  97. Heterogeneity for mutations in medium chain acyl‐CoA dehydrogenase deficiency in the UK population

    Article • Clinical Genetics, October 1991, Wiley

    Professor Paul C Engel

  98. Understanding MCAD deficiency: one cause of cot death

    Article • Current Biology, June 1991, Elsevier

    Professor Paul C Engel

  99. A circular dichroism study of the pH‐dependent activation/inactivation equilibrium in the glutamate dehydrogenase of Clostridium symbiosum

    Article • FEBS Letters, March 1990, Wiley

    Professor Paul C Engel

  100. BamHI and Mspl RFLP's in strong linkage disequilibrium at the medium chain acyl-Coenzyme A dehydrogenase locus (ACADM chromsome 1)

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Professor Paul C Engel

  101. Pstl RFLP at the medium chain acyl-Coenzyme A dehydrogenase locus (ACADM chromsome 1)

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Professor Paul C Engel

  102. CoA-persulphide: a possible in vivo inhibitor of mammalian short-chain acyl-CoA dehydrogenase

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, June 1987, Elsevier

    Professor Paul C Engel

  103. Crystallization of an NAD+-dependent glutamate dehydrogenase from Clostridium symbiosum

    Article • Journal of Molecular Biology, January 1985, Elsevier

    Professor Paul C Engel

  104. Kinetic studies of Ox-liver glutamate dehydrogenase oxidative deamination of two glutamate analogues, L-threo-γ-methylglutamate and L-α-amino-γ-nitraminobutyrate, in the presence of the allosteric effector ADP

    Article • International Journal of Biochemistry, January 1985, Elsevier

    Professor Paul C Engel

  105. A kinetic study of the oxidative deamination of L‐glutamate by Peptostreptococcus asaccharolyticus glutamate dehydrogenase using a variety of coenzymes

    Article • European Journal of Biochemistry, September 1984, Wiley

    Professor Paul C Engel

  106. Chapter 3 Enzyme kinetics

    Article • January 1984, Elsevier

    Professor Paul C Engel

  107. Beef liver glutamate dehydrogenase : Effects of partial proteolysis with chymotrypsin

    Article • International Journal of Biochemistry, January 1983, Elsevier

    Professor Paul C Engel

  108. Beef liver glutamate dehydrogenase: A study of the oxidation of various alternative amino acid substrates retaining the correct spacing of the two carboxylate groups

    Article • International Journal of Biochemistry, January 1983, Elsevier

    Professor Paul C Engel

  109. A convenient and rapid method for the complete removal of CoA from butyryl-CoA dehydrogenase

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, September 1982, Elsevier

    Professor Paul C Engel

  110. The reactions of pyridoxal 5′-phosphate with the M4 and H4 isoenzymes of pig lactate dehydrogenase

    Article • Archives of Biochemistry and Biophysics, May 1982, Elsevier

    Professor Paul C Engel

  111. A resonance Raman study on the nature of charge‐transfer interactions in butyryl CoA dehydrogenase

    Article • FEBS Letters, February 1982, Wiley

    Professor Paul C Engel

  112. Enzyme Kinetics

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  113. pH effects

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  114. The King and Altman procedure

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  115. More than one substrate

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  116. One-substrate kinetics

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  117. Inhibitors, activators and inactivators

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  118. Non-linear kinetics and the concept of allosteric interaction

    Article • January 1981, Springer Science + Business Media

    Professor Paul C Engel

  119. [43] Butyryl-CoA dehydrogenase from Megasphaera elsdenii

    Article • January 1981, Elsevier

    Professor Paul C Engel

  120. A re-examination of the reaction between Ox liver glutamate dehydrogenase and 1-fluoro-2,4-dinitrobenzene

    Article • Archives of Biochemistry and Biophysics, August 1979, Elsevier

    Professor Paul C Engel

  121. Causes and elimination of erratic blanks in enzymatic metabolite assays involving the use of NAD+ in alkaline hydrazine buffers: Improved conditions for the assay of l-glutamate, l-lactate, and other metabolites

    Article • Analytical Biochemistry, August 1978, Elsevier

    Professor Paul C Engel

  122. The detection of amino acid sequence homology: A new scoring method based on the genetic code with allowance for redundancy

    Article • Journal of Theoretical Biology, May 1978, Elsevier

    Professor Paul C Engel

  123. Problems in the application of gel filtration to the desalting of organic compounds: Retardation of aromatic and heteroaromatic anions by commonly used salts

    Article • Analytical Biochemistry, October 1977, Elsevier

    Professor Paul C Engel

  124. Equilibrium protection studies of the interaction of bovine glutamate dehydrogenase with purine nucleotide effectors

    Article • FEBS Letters, October 1975, Wiley

    Professor Paul C Engel

  125. Sequence homologies among pyridine nucleotide‐linked dehydrogenases: Possible partial gene duplications in glyceraldehyde‐3‐phosphate dehydrogenase

    Article • FEBS Letters, June 1973, Wiley

    Professor Paul C Engel

  126. Kinetics and Mechanism of Glutamate Dehydrogenase

    Article • January 1970, Springer Science + Business Media

    Professor Paul C Engel

  127. Antagonistic homotropic interactions as a possible explanation of coenzyme activation of glutamate dehydrogenase

    Article • FEBS Letters, October 1968, Wiley

    Professor Paul C Engel

  128. Biochemical Characterisation of Mutations of Human Medium-Chain Acyl-CoA Dehydrogenase

    Article • Springer Science + Business Media

    Professor Paul C Engel