All Stories

  1. Gasotransmitters and noble gases in cardioprotection: unraveling molecular pathways for future therapeutic strategies

    Article • Basic Research in Cardiology, June 2024, Springer Science + Business Media

    Professor Pasquale Pagliaro

  2. Reperfusion Injury in Patients With Acute Myocardial Infarction

    Article • Journal of the American College of Cardiology, June 2024, Elsevier

    Professor Pasquale Pagliaro

  3. Enhancing Heart Transplantation: Utilizing Gas-Loaded Nanocarriers to Mitigate Cold/Hypoxia Stress

    Article • International Journal of Molecular Sciences, May 2024, MDPI AG

    Professor Pasquale Pagliaro

  4. Expanding the Frontiers of Guardian Antioxidant Selenoproteins in Cardiovascular Pathophysiology

    Article • Antioxidants & Redox Signaling, March 2024, Mary Ann Liebert Inc

    Professor Pasquale Pagliaro

  5. Enhancing Vitamin D3 Efficacy: Insights from Complexation with Cyclodextrin Nanosponges and Its Impact on Gut–Brain Axes in Physiology and IBS Syndrome

    Article • International Journal of Molecular Sciences, February 2024, MDPI AG

    Professor Pasquale Pagliaro

  6. Clinical Applications for Gasotransmitters in the Cardiovascular System: Are We There Yet?

    Article • International Journal of Molecular Sciences, August 2023, MDPI AG

    Professor Pasquale Pagliaro

  7. Inhibitors of NLRP3 Inflammasome in Ischemic Heart Disease: Focus on Functional and Redox Aspects

    Article • Antioxidants, July 2023, MDPI AG

    Professor Pasquale Pagliaro

  8. Oxygen Nanocarriers for Improving Cardioplegic Solution Performance: Physico-Chemical Characterization

    Article • International Journal of Molecular Sciences, June 2023, MDPI AG

    Professor Pasquale Pagliaro

  9. Platelets and Cardioprotection: The Role of Nitric Oxide and Carbon Oxide

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Professor Pasquale Pagliaro

  10. Ischemic Conditioning to Reduce Fatigue in Isometric Skeletal Muscle Contraction

    Article • Biology, March 2023, MDPI AG

    Professor Pasquale Pagliaro

  11. Developing New Cyclodextrin-Based Nanosponges Complexes to Improve Vitamin D Absorption in an In Vitro Study

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Professor Pasquale Pagliaro

  12. Pathways for Cardioprotection in Perspective: Focus on Remote Conditioning and Extracellular Vesicles

    Article • Biology, February 2023, MDPI AG

    Professor Pasquale Pagliaro

  13. Electrocardiogram

    Article • September 2022, Taylor & Francis

    Professor Pasquale Pagliaro

  14. Arterial Pressure

    Article • September 2022, Taylor & Francis

    Professor Pasquale Pagliaro

  15. Pulmonary Circulation

    Article • September 2022, Taylor & Francis

    Professor Pasquale Pagliaro

  16. Lymphatic Circulation

    Article • September 2022, Taylor & Francis

    Professor Pasquale Pagliaro

  17. HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCε Activation

    Article • Antioxidants, February 2022, MDPI AG

    Professor Pasquale Pagliaro

  18. Do the Current Guidelines for Heart Failure Diagnosis and Treatment Fit with Clinical Complexity?

    Article • Journal of Clinical Medicine, February 2022, MDPI AG

    Prof Anna Vittoria Mattioli, Professor Pasquale Pagliaro

  19. A TRICk to Improve the Effectiveness of RIC: Role of Limb Temperature in Enhancing the Effectiveness of Remote Ischemic Conditioning

    Article • Biology, January 2022, MDPI AG

    Professor Pasquale Pagliaro

  20. Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function

    Article • Basic Research in Cardiology, October 2021, Springer Science + Business Media

    Professor Pasquale Pagliaro

  21. Percutaneous Coronary Intervention (PCI) Reprograms Circulating Extracellular Vesicles from ACS Patients Impairing Their Cardio-Protective Properties

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Professor Pasquale Pagliaro

  22. Cyclic Nigerosyl-Nigerose as Oxygen Nanocarrier to Protect Cellular Models from Hypoxia/Reoxygenation Injury: Implications from an In Vitro Model

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    Professor Pasquale Pagliaro

  23. Extracellular Vesicles in Comorbidities Associated with Ischaemic Heart Disease: Focus on Sex, an Overlooked Factor

    Article • Journal of Clinical Medicine, January 2021, MDPI AG

    Professor Pasquale Pagliaro

  24. The Inflammatory Cytokine IL-3 Hampers Cardioprotection Mediated by Endothelial Cell-Derived Extracellular Vesicles Possibly via Their Protein Cargo

    Article • Cells, December 2020, MDPI AG

    Professor Pasquale Pagliaro

  25. Is macrophages heterogeneity important in determining COVID-19 lethality?

    Article • Medical Hypotheses, October 2020, Elsevier

    Professor Pasquale Pagliaro

  26. Sex‐related differences in COVID‐19 lethality

    Article • British Journal of Pharmacology, August 2020, Wiley

    Professor Pasquale Pagliaro

  27. Diabetic Cardiomyopathy and Ischemic Heart Disease: Prevention and Therapy by Exercise and Conditioning

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    Professor Antigone Lazou, Professor Pasquale Pagliaro

  28. Effect of hyperglycaemia and diabetes on acute myocardial ischaemia–reperfusion injury and cardioprotection by ischaemic conditioning protocols

    Article • British Journal of Pharmacology, March 2020, Wiley

    Professor Antigone Lazou, Professor Pasquale Pagliaro

  29. Obesity and Cardioprotection

    Article • Current Medicinal Chemistry, February 2020, Bentham Science Publishers

    Professor Pasquale Pagliaro

  30. From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity: A Translational Overview

    Article • Antioxidants & Redox Signaling, June 2019, Mary Ann Liebert Inc

    Professor Pasquale Pagliaro

  31. Cardioprotection of PLGA/gelatine cardiac patches functionalised with adenosine in a large animal model of ischaemia and reperfusion injury: A feasibility study

    Article • Journal of Tissue Engineering and Regenerative Medicine, May 2019, Wiley

    Professor Pasquale Pagliaro

  32. Hemodynamic abnormalities during muscle metaboreflex activation in patients with type 2 diabetes mellitus

    Article • Journal of Applied Physiology, February 2019, American Physiological Society

    Professor Pasquale Pagliaro

  33. Circulating blood cells and extracellular vesicles in acute cardioprotection

    Article • Cardiovascular Research, December 2018, Oxford University Press (OUP)

    Dr Sean Michael Davidson, Prof. Lucio Barile, Dr. Hector Cabrera-Fuentes, Professor Pasquale Pagliaro

  34. Innate immunity as a target for acute cardioprotection

    Article • Cardiovascular Research, December 2018, Oxford University Press (OUP)

    Dr Sean Michael Davidson, Dr. Hector Cabrera-Fuentes, Professor Pasquale Pagliaro

  35. Role of NLRP-3 Inflammasome in Hypertension: A Potential Therapeutic Target

    Article • Current Pharmaceutical Biotechnology, November 2018, Bentham Science Publishers

    Professor Pasquale Pagliaro, Tommaso Angelone, CARMINE ROCCA

  36. Editorial: Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease

    Article • Frontiers in Physiology, November 2018, Frontiers

    Professor Pasquale Pagliaro

  37. Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

    Article • Basic Research in Cardiology, August 2018, Springer Science + Business Media

    Professor Pasquale Pagliaro

  38. Cardioprotective Properties of Human Platelets Are Lost in Uncontrolled Diabetes Mellitus: A Study in Isolated Rat Hearts

    Article • Frontiers in Physiology, July 2018, Frontiers

    Professor Pasquale Pagliaro

  39. Silica nanoparticles actively engage with mesenchymal stem cells in improving acute functional cardiac integration

    Article • Nanomedicine, June 2018, Future Medicine

    Professor Claudia Giachino, Professor Pasquale Pagliaro

  40. Notch1 Mediates Preconditioning Protection Induced by GPER in Normotensive and Hypertensive Female Rat Hearts

    Article • Frontiers in Physiology, May 2018, Frontiers

    Professor Pasquale Pagliaro

  41. Metaflammation: Tissue-Specific Alterations of the NLRP3 Inflammasome Platform in Metabolic Syndrome

    Article • Current Medicinal Chemistry, April 2018, Bentham Science Publishers

    Professor Pasquale Pagliaro, Prof. Massimo COLLINO

  42. Editorial: Alteration of Redox Equilibrium, Inflammation and Progression of Disease

    Article • Current Medicinal Chemistry, April 2018, Bentham Science Publishers

    Professor Pasquale Pagliaro

  43. Mitochondria in Cardiac Postconditioning

    Article • Frontiers in Physiology, March 2018, Frontiers

    Professor Pasquale Pagliaro

  44. Redox Aspects of Chaperones in Cardiac Function

    Article • Frontiers in Physiology, March 2018, Frontiers

    Professor Pasquale Pagliaro

  45. Antineoplastic Drug-Induced Cardiotoxicity: A Redox Perspective

    Article • Frontiers in Physiology, March 2018, Frontiers

    Professor Pasquale Pagliaro

  46. α-Cyclodextrin and α-Cyclodextrin Polymers as Oxygen Nanocarriers to Limit Hypoxia/Reoxygenation Injury: Implications from an In Vitro Model

    Article • Polymers, February 2018, MDPI AG

    Professor Pasquale Pagliaro

  47. Apelin-induced cardioprotection against ischaemia/reperfusion injury: roles of epidermal growth factor and Src

    Article • Acta Physiologica, August 2017, Wiley

    Professor Claudia Giachino, Professor Pasquale Pagliaro

  48. Obestatin regulates cardiovascular function and promotes cardioprotection through the nitric oxide pathway

    Article • Journal of Cellular and Molecular Medicine, July 2017, Wiley

    Professor Pasquale Pagliaro

  49. Cardioprotective effects of calcitonin gene-related peptide in isolated rat heart and in H9c2 cells via redox signaling

    Article • Biomedicine & Pharmacotherapy, June 2017, Elsevier

    Professor Pasquale Pagliaro

  50. Platelets, diabetes and myocardial ischemia/reperfusion injury

    Article • Cardiovascular Diabetology, May 2017, Springer Science + Business Media

    Professor Pasquale Pagliaro

  51. Nanoprecipitated catestatin released from pharmacologically active microcarriers (PAMs) exerts pro-survival effects on MSC

    Article • International Journal of Pharmaceutics, May 2017, Elsevier

    Professor Pasquale Pagliaro

  52. Myocardial ischemia/reperfusion upregulates the transcription of the Neuregulin1 receptor ErbB3, but only postconditioning preserves protein translation: Role in oxidative stress

    Article • International Journal of Cardiology, April 2017, Elsevier

    Professor Pasquale Pagliaro

  53. role of hypertension, hypertrophy and therapy in conditioning ischemia reperfusion injury

    Article • Journal of Cardiovascular Medicine, September 2016, Wolters Kluwer Health

    Professor Pasquale Pagliaro

  54. Pathophysiology of anthracycline cardiotoxicity

    Article • Journal of Cardiovascular Medicine, May 2016, Wolters Kluwer Health

    Professor Pasquale Pagliaro

  55. A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity

    Article • Journal of Cardiovascular Medicine, May 2016, Wolters Kluwer Health

    Professor Pasquale Pagliaro

  56. A recommended practical approach to the management of target therapy and angiogenesis inhibitors cardiotoxicity

    Article • Journal of Cardiovascular Medicine, May 2016, Wolters Kluwer Health

    Professor Pasquale Pagliaro

  57. Editorial (Thematic Issue: Protection, Repair and Regeneration of Achybreaky Heart)

    Article • Current Drug Targets, August 2015, Bentham Science Publishers

    Professor Pasquale Pagliaro

  58. Endogenous Cardioprotective Agents: Role in Pre and Postconditioning

    Article • Current Drug Targets, August 2015, Bentham Science Publishers

    Professor Pasquale Pagliaro

  59. A man is as young as his endothelium

    Article • July 2015, The Physiological Society

    Professor Pasquale Pagliaro

  60. Preconditioning cardioprotection and exercise performance: a radical point of view

    Article • Sport Sciences for Health, June 2015, Springer Science + Business Media

    Professor Pasquale Pagliaro

  61. Redox signalling and cardioprotection: translatability and mechanism

    Article • British Journal of Pharmacology, January 2015, Wiley

    Professor Pasquale Pagliaro

  62. cardioprotection by exercise

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Professor Pasquale Pagliaro

  63. Redox balance and cardioprotection

    Article • Basic Research in Cardiology, October 2013, Springer Science + Business Media

    Professor Pasquale Pagliaro

  64. The switch from protective signalling to deleterious oxidative/nitrosative/nitrative stress

    Article • Journal of Cardiovascular Medicine, October 2013, Wolters Kluwer Health

    Professor Pasquale Pagliaro

  65. Mitochondrial Pathways, Permeability Transition Pore, and Redox Signaling in Cardioprotection: Therapeutic Implications

    Article • Antioxidants & Redox Signaling, February 2013, Mary Ann Liebert Inc

    Professor Pasquale Pagliaro

  66. Cardiac Postconditioning

    Article • Antioxidants & Redox Signaling, March 2011, Mary Ann Liebert Inc

    Professor Pasquale Pagliaro

  67. Cardioprotective Pathways During Reperfusion: Focus on Redox Signaling and Other Modalities of Cell Signaling

    Article • Antioxidants & Redox Signaling, March 2011, Mary Ann Liebert Inc

    Professor Pasquale Pagliaro

  68. Cardioprotection: A radical view

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, July 2009, Elsevier

    Professor Pasquale Pagliaro

  69. Intermittent Adenosine at the Beginning of Reperfusion Does Not Trigger Cardioprotection

    Article • Journal of Surgical Research, May 2009, Elsevier

    Professor Pasquale Pagliaro

  70. Protective effect of hydrogen sulfide against oxidative stress of myoblasts

    Article • Journal of Molecular and Cellular Cardiology, November 2008, Elsevier

    Professor Pasquale Pagliaro

  71. Nitric Oxide Synthase Function in Exercise

    Article • Current Enzyme Inhibition, February 2008, Bentham Science Publishers

    Professor Pasquale Pagliaro

  72. Postconditioning and intermittent bradykinin induced cardioprotection require cyclooxygenase activation and prostacyclin release during reperfusion

    Article • Basic Research in Cardiology, January 2008, Springer Science + Business Media

    Professor Pasquale Pagliaro

  73. Effect of endothelins on the cardiovascular system

    Article • Journal of Cardiovascular Medicine, September 2006, Wolters Kluwer Health

    Professor Pasquale Pagliaro

  74. Morphological characterization of GFP stably transfected adult mesenchymal bone marrow stem cells

    Article • Journal of Anatomy, January 2006, Wiley

    Professor Pasquale Pagliaro

  75. Myocardial protection from ischemic preconditioning is not blocked by sub-chronic inhibition of carnitine palmitoyltransferase I

    Article • Life Sciences, September 2005, Elsevier

    Professor Pasquale Pagliaro

  76. Rethinking the Renin-Angiotensin System and Its Role in Cardiovascular Regulation

    Article • Cardiovascular Drugs and Therapy, January 2005, Springer Science + Business Media

    Professor Pasquale Pagliaro

  77. Haemodynamic responses following intermittent supramaximal exercise in athletes

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, October 2004, Wiley

    Professor Pasquale Pagliaro

  78. The anti-inflammatory agents Siblings Nitroxyl (HNO) and Nitric Oxide (NO) in Cardioprotection

    Article • Drug Design Reviews - Online, October 2004, Bentham Science Publishers

    Professor Pasquale Pagliaro

  79. Differential biological effects of products of nitric oxide (NO) synthase: it is not enough to say NO

    Article • Life Sciences, September 2003, Elsevier

    Professor Pasquale Pagliaro

  80. Comparison between the effects of pentobarbital or ketamine/nitrous oxide anesthesia on metabolic and endothelial components of coronary reactive hyperemia

    Article • Life Sciences, June 2001, Elsevier

    Professor Pasquale Pagliaro

  81. Ischemic preconditioning

    Article • Life Sciences, May 2001, Elsevier

    Professor Pasquale Pagliaro

  82. Specificity of synergistic coronary flow enhancement by adenosine and pulsatile perfusion in the dog

    Article • The Journal of Physiology, October 1999, Wiley

    Professor Pasquale Pagliaro

  83. The effects of ischemic preconditioning on resting coronary flow and reactive hyperemia: Involvement of A1 adenosine receptors

    Article • Life Sciences, February 1999, Elsevier

    Professor Pasquale Pagliaro

  84. The Gaboon viper, Bitis gabonica: Hemorrhagic, metabolic, cardiovascular and clinical effects of the venom

    Article • Life Sciences, July 1997, Elsevier

    Professor Pasquale Pagliaro

  85. Myocardial, neural and vascular aspects of ischemic preconditioning

    Article • Life Sciences, September 1996, Elsevier

    Professor Pasquale Pagliaro

  86. The effect of the inhibition of the endothelial release of nitric oxide on coronary reactive hyperaemia in the anaesthetized dog

    Article • Life Sciences, January 1994, Elsevier

    Professor Pasquale Pagliaro