All Stories

  1. In vivo evaluation of purified methanolic extract and medicagenic acid saponin from Chenopodium bonus-henricus L. roots in a rotenone-induced Parkinson’s disease model
  2. Screening of Cytotoxic and Genotoxic Activities of Subcritical Water Extracts from R. damascena and R. alba Flowers
  3. Correction: Milusheva et al. In Silico, In Vitro, and Ex Vivo Biological Activity of Some Novel Mebeverine Precursors. Biomedicines 2023, 11, 605
  4. Polyprenylated Acylphloroglucinols from Hypericum rochelii and Hypericum olympicum—Cytotoxic Effects on Non-Tumorigenic Cell Lines and Antibacterial Potential
  5. Phenolic Compounds from Hypericum cerastoides (Spach) N. Robson: Dereplication via UHPLC-HRMS/MS, Isolation, Identification, and Preliminary Biological Evaluation Focusing on Radical-Scavenging, Anti-α-Glucosidase, and Pro-Lipase Activities
  6. Phytochemical Characterization and Anti-Biofilm Activity of Primula veris L. Roots
  7. Cytotoxic acylphloroglucinols from the aerial parts of Hypericum hirsutum L. (Hypericaceae)
  8. Flavonoids and Saponins from Two Chenopodium Species (C. foliosum Asch. and C. bonus-henricus L.)—Preliminary Evaluation for hMAO-A/B, Neuroprotective Activity, and Validated UHPLC-HRMS Quantification of Ethanolic Extract from C. foliosum
  9. N-(4-Methoxyphenethyl)-2-oxo-2H-chromene-3-carboxamide
  10. Synthesis, Anti-Inflammatory Activity, and Docking Simulation of a Novel Styryl Quinolinium Derivative
  11. Phenolic Constituents from Hypericum aucheri Jaub et. Spach—Isolation, Identification, and Preliminary Evaluation for hMAO-A/B and Neuroprotective Activity
  12. Synthesis of Novel Sulfonamide Derivatives Featuring 1-(Methylsulfonyl)-4-(2,3,4-trimethoxybenzyl)piperazine Core Structures
  13. Attempted Synthesis of the Pseudomonas aeruginosa Metabolite 2-Benzyl-4(1H)-quinolone and Formation of 3-Methylamino-2-(2-nitrobenzoyl)-4H-naphthalen-1-one as an Unexpected Product
  14. Concise Synthesis of Pseudane IX, Its N-Oxide, and Novel Carboxamide Analogs with Antibacterial Activity
  15. 2-Amino-N-Phenethylbenzamides for Irritable Bowel Syndrome Treatment
  16. Inula salicina L.: Insights into Its Polyphenolic Constituents and Biological Activity
  17. (±)-R,S-2-Chloro-N-(4-methyl-2-oxo-2H-chromen-7-yl)-2-phenylacetamide
  18. UHPLC-HRMS-based profiling and simultaneous quantification of the hydrophilic phenolic compounds from the aerial parts of Hypericum aucheri Jaub. & Spach (Hypericaceae)
  19. N-(3-chlorophenethyl)-4-nitrobenzamide
  20. In Silico and Chromatographic Methods for Analysis of Biotransformation of Prospective Neuroprotective Pyrrole-Based Hydrazone in Isolated Rat Hepatocytes
  21. N-(2,2-diphenylethyl)-4-nitrobenzamide
  22. Novel Flurbiprofen Derivatives as Antioxidant and Anti-Inflammatory Agents: Synthesis, In Silico, and In Vitro Biological Evaluation
  23. Novel Anthranilic Acid Hybrids—An Alternative Weapon against Inflammatory Diseases
  24. Naturally Occurring Simple Oxygenated Benzophenones: Structural Diversity, Distribution, and Biological Properties
  25. Synthesis, Molecular Docking, and Biological Evaluation of Novel Anthranilic Acid Hybrid and Its Diamides as Antispasmodics
  26. 2-(2-Fluoro-[1,1′-biphenyl]-4-yl)-N-(4-methyl-2-oxo-2H-chromen-7-yl)propanamide
  27. (±)-N-(1,2-Bis(3,4-dimethoxyphenyl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide
  28. Synthesis, Molecular Docking, Molecular Dynamics Studies, and In Vitro Biological Evaluation of New Biofunctional Ketoprofen Derivatives with Different N-Containing Heterocycles
  29. Anticancer Podophyllotoxin Recovery from Juniper Leaves at Atmospheric and High Pressure Using Eco-Friendly Solvents
  30. Cytotoxic and Antibacterial Prenylated Acylphloroglucinols from Hypericum olympicum L.
  31. In Silico, In Vitro, and Ex Vivo Biological Activity of Some Novel Mebeverine Precursors
  32. Outstanding Antibacterial Activity of Hypericum rochelii—Comparison of the Antimicrobial Effects of Extracts and Fractions from Four Hypericum Species Growing in Bulgaria with a Focus on Prenylated Phloroglucinols
  33. Novel artesunate–pyrimidine-based hybrids with anticancer potential against multidrug-resistant cancer cells
  34. Synthesis, In Vitro Anti-Inflammatory Activity, and HRMS Analysis of New Amphetamine Derivatives
  35. Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro
  36. Synthesis, In Silico, and In Vitro Biological Evaluation of New Furan Hybrid Molecules
  37. In Vitro Study of the Biological Potential of Wastewater Obtained after the Distillation of Four Bulgarian Oil-Bearing Roses
  38. Redox-Modulating Capacity and Antineoplastic Activity of Wastewater Obtained from the Distillation of the Essential Oils of Four Bulgarian Oil-Bearing Roses
  39. Innovative Biochemometric Approach to the Metabolite and Biological Profiling of the Balkan Thistle (Cirsium appendiculatum Griseb.), Asteraceae
  40. UHPLC-Orbitrap-MS Tentative Identification of 51 Oleraceins (Cyclo-Dopa Amides) in Portulaca oleracea L. Cluster Analysis and MS2 Filtering by Mass Difference
  41. Simultaneous quantification of the major flavonoids from wild spinach by UHPLC-HRMS and their neuroprotective effects in a model of H2O2-induced oxidative stress on SH-SY5Y cells
  42. UHPLC-Orbitrap-HRMS Identification of 51 Oleraceins (Cyclo-Dopa Amides) in Portulaca oleracea L. Cluster Analysis and MS2 Filtering by Mass Difference
  43. Junipers of Various Origins as Potential Sources of the Anticancer Drug Precursor Podophyllotoxin
  44. Validated UHPLC-HRMS method for simultaneous quantification of flavonoid contents in the aerial parts of Chenopodium bonus-henricus L. (wild spinach)
  45. Saponins from the roots of Chenopodium bonus-henricus L. with neuroprotective and anti-α-glucosidase activities
  46. A New Flavonol Acylglucoside from Inula aschersoniana Janka Var. aschersoniana
  47. Ultra-high-performance liquid chromatography – high-resolution mass spectrometry profiling and hepatoprotective activity of purified saponin and flavonoid fractions from the aerial parts of wild spinach (Chenopodium bonus-henricus L.)
  48. Neuroprotective, anti-α-glucosidase and prolipase active flavonoids from Good King Henry (Chenopodium bonus-henricus L.)
  49. Hepatoprotective activity of a purified methanol extract and saponins from the roots of Chenopodium bonus-henricus L.
  50. UHPLC-HRMS based flavonoid profiling of the aerial parts of Chenopodium foliosum Asch. (Amaranthaceae)
  51. Phytotherapeutic approaches to treatment and prophylaxis in pediatric practice
  52. A comparative study of UHPLC/Orbitrap MS metabolomics profiles and biological properties of Asphodeline taurica from Bulgaria and Turkey
  53. New Δ-tocotrienol derivatives from Colombian propolis
  54. Synthesis of Two Novel Homologous Polyphosphoesters Containing Aminophosphonate Units and Cytotoxicity of Some Low-Molecular and Polymeric Aminophosphonate Derivatives
  55. Saponins from the roots of Chenopodium bonus-henricus L.
  56. Cytotoxic prenylated acylphloroglucinols from Hypericum annulatum
  57. Isofraxisecoside, a new coumarin-secoiridoid from the stem bark of Fraxinus xanthoxyloides
  58. Identification of phenolic components via LC–MS analysis and biological activities of two Centaurea species: C. drabifolia subsp. drabifolia and C. lycopifolia
  59. Chenopodium bonus - henricus L. – A source of hepatoprotective flavonoids
  60. Pharmacognostic investigations of the aerial parts of Chenopodium foliosum Asch. and radical-scavenging activities of five flavonoids isolated from methanol extract of the plant
  61. Cytoprotective and antioxidant effects of phenolic compounds from Haberlea rhodopensis Friv. (Gesneriaceae)
  62. Cytotoxic Effects and Multidrug Resistance Modulation by Five Benzophenones and a Xanthone Isolated fromHypericum AnnulatumMoris SUBSP.Annulatum
  63. In vitro investigation of the antiproliferative and proapoptotic effects of hyperatomarin – a bicyclic prenylated acylphloroglucinol from Hypericum annulatum Moris subsp. annulatum against human tumor and endothelial cells
  64. Benzophenones and flavonoids from Hypericum maculatum and their antioxidant activities
  65. Elegaphenone and 7-epi-clusianone, the major cytotoxic constituents ofHypericum elegans
  66. Flavonol glycosides from Chenopodium foliosum Asch
  67. Radical scavenging and antioxidant activities of methanolic extracts fromHypericumspecies growing in Bulgaria
  68. BenzophenoneO-glycosides fromHypericum elegans
  69. Cytotoxic effects of hyperatomarin, a prenylated phloroglucinol from Hypericum annulatum Moris subsp. annulatum, in a panel of malignant cell lines
  70. A new isocoumarin fromHypericum annulatum
  71. Flavonoids and a xanthone from Hypericum umbellatum (Guttiferae)
  72. Cytoprotective Effects of 5 Benzophenones and a Xanthone from Hypericum annulatum in Models of Epirubicin-Induced Cytotoxicity: SARAnalysis and Mechanistic Investigations
  73. Effect of benzophenones from Hypericum annulatum on carbon tetrachloride-induced toxicity in freshly isolated rat hepatocytes
  74. Simultaneous determination of benzophenones and gentisein inhypericum annulatum moris by high-performance liquid chromatography
  75. Two benzophenone O-arabinosides and a chromone from Hypericum annulatum
  76. Benzophenone O -glucoside, a biogenic precursor of 1,3,7-trioxygenated xanthones in Hypericum annulatum
  77. Mangiferin and isomangiferin in some Hypericum species