All Stories

  1. Using quantitative modeling tools to assess pharmacokinetic bias in epidemiological studies showing associations between biomarkers and health outcomes at low exposures
  2. Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids
  3. Quantitative bias analysis of the association between subclinical thyroid disease and two perfluoroalkyl substances in a single study
  4. Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling
  5. The Evolving Druggability and Developability Space: Chemically Modified New Modalities and Emerging Small Molecules
  6. Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
  7. Impact of diet on irinotecan toxicity in mice
  8. Utilizing in vitro transporter data in IVIVE-PBPK: an overview
  9. Role of Toll-like receptor 4 in drug-drug interaction between paclitaxel and irinotecan in vitro
  10. Implications of drug-metabolizing enzymes in biologics–small molecule drug (SMD) interactions
  11. In Vitro Approaches to Study Regulation of Hepatic Cytochrome P450 (CYP) 3A Expression by Paclitaxel and Rifampicin
  12. Impact of obesity on accumulation of the toxic irinotecan metabolite, SN-38, in mice
  13. Effect of pentoxifylline on the pharmacokinetics of rosiglitazone in Wistar rats