All Stories

  1. Biosynthesis of Bioactive Compounds from Plants
  2. Drug Repurposing for Antidiabetics Discovery and Development
  3. Environment as an Active Variable in Retrosynthesis of Bioactive Compounds of Therapeutic Importance
  4. Harnessing Drug Repurposing and Polypharmacology for Therapeutic Innovation in Neglected Tropical Diseases (NTDS)
  5. Global Burden of Elevated LDL-C
  6. Polyphenol-Rich Formulations and Their Multi-Target Interactions With Molecular Pathways in Cancer Cells
  7. Beyond traditional medicine: Erythrophyleum suaveolens (Guill. & Perr.) Brenan shows promising antidiabetic activity in experimentally induced type II diabetes
  8. Nrf-2/HO-1 modulatory effects on Ocimum gratissimum flavonoid-rich leaf extract in the livers of streptozotocin-induced diabetic rats
  9. Deciphering the mechanisms underlying the dual-target inhibition of carbohydrate-digesting and neurodegenerative enzymes by Syzygium aromaticum (L.) Merr. & L.M. via molecular docking and dynamics simulations
  10. Effects of <I>Celosia argentea</I> L. leaf on Monosodium Glutamate (MSG)-Induced Uterine Leiomyoma In Wistar Rats: Experimental and Computational Perspectives
  11. Evaluation of the ethanolic extract of Mondai whitei (Hook.f.) Skeels for their antioxidant, anti-inflammatory and antidiabetic properties
  12. Emerging trends in cancer biomarkers and their clinical effect on personalized treatment
  13. The Role of Dietary and Lifestyle Factors in the Formation of Premature Ovarian Insufficiency
  14. Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential
  15. Nutritional, antioxidant, enzyme inhibitory and toxicity assessments of an herbal formulation using in vitro, ex vivo, and in vivo approaches
  16. The UPR-oxidative stress nexus in diabetes and obesity: Exploring innovative therapeutic approaches for metabolic control
  17. Anti-breast cancer effects of Pterocarpus soyauxii Taub aqueous extract and its compounds by integrating ADMET, network pharmacology, molecular docking, dynamic simulation, CLC-Pred and pdCSM-Cancer/PPI approaches, and in vitro validation
  18. Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats
  19. Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies
  20. Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies
  21. Assessment of nutritional, antioxidant, and antidiabetic properties of the BF 1 herbal formulation via in vitro and ex vivo approaches
  22. Implications of plastic-derived endocrine disruptors on human health
  23. Antioxidant and antidiabetic activities of Gossypium barbadense L. leaves using in vitro, and in silico methods
  24. Interplay of the pathophysiological mechanisms of non-alcoholic fatty liver disease, diabetes mellitus, and inflammation: A growing threat to public health
  25. Protective effects of flavonoid-rich extracts from Hibiscus sabdariffa leaves on streptozotocin-induced testicular damage in rats
  26. Experimental and computational analyses of the anti-alzheimer and antidiabetic effects of flavonoid-rich extract of avocado seeds (Persea americana Mill.)
  27. Deciphering the in silico molecular mechanism of coumestrol activity for uterine fibroids remedy: a promising estrogenic target drug candidate
  28. Investigative assessment of the neuro-modulatory potentials of cannabichromene in TrkB/BDNF-mediated neurosignaling pathway
  29. Ferroptosis as the new approach to cancer therapy
  30. Albizia ferruginea (Guill. & Perr.) Benth. leaf abates deregulation of P53, IRS, HsD17β2, FTO, and CYP11a genes in polycystic ovarian syndrome rat
  31. Effect of Hibiscus sabdariffa L. leaf flavonoid-rich extract on Nrf-2 and HO-1 pathways in liver damage of streptozotocin-induced diabetic rats
  32. Energy metabolism and spermatogenesis
  33. Network Pharmacology, Molecular Dynamics and In Vitro Assessments of Indigenous Herbal Formulations for Alzheimer’s Therapy
  34. Oxidative Stress-induced Hormonal Disruption in Male Reproduction
  35. Petiveria alliacea L. extract protects against streptozotocin-induced type-2 diabetes by modulating the cAMP/PKA/CREB/cFOS pathway
  36. Studies on melatonin intervention in reactive oxygen species-linked autophagy of neocarzinostatin-induced varicocele infertility in male Swiss Albino mice
  37. Preclinical antidiabetic and antioxidant effects of Erythrophleum africanum (benth.) harms in streptozotocin-induced diabetic nephropathy
  38. Attenuation of PI3K/AKT signaling pathway by Ocimum gratissimum leaf flavonoid-rich extracts in streptozotocin-induced diabetic male rats
  39. Mitophagy and spermatogenesis: Role and mechanisms
  40. Spilanthes filicaulis (Schumach. & Thonn.) C. D Adam leaf extract prevents assault of streptozotocin on liver cells via inhibition of oxidative stress and activation of the NrF2/Keap1, PPARγ, and PTP1B signaling pathways
  41. Ocimum gratissimum L. leaf flavonoid-rich extracts reduced the expression of p53 and VCAM in streptozotocin-induced cardiomyopathy rats
  42. Spilanthes filicaulis (Schumach. & Thonn.) C.D. Adams leaves protects against streptozotocin-induced diabetic nephropathy
  43. Kigelia africana (Lam.) Benth. fruit inhibits iron-induced lipid peroxidation and ?-amylase enzyme activity
  44. Production, acceptability, nutritional and pasting properties of orange-flesh sweet potato, cowpea and banana flour mix
  45. Alkaloid-rich extract of Lannea egregia leaf protect against cardiomyopathy in streptozotocin-induced type 2 diabetic rats
  46. Exploring beetroot (Beta vulgaris L.) for diabetes mellitus and Alzheimer's disease dual therapy: in vitro and computational studies
  47. Elemental evaluation, nutritional analysis, GC-MS analysis and ameliorative effects of Artocarpus communis J.R.Forst. & G.Forst. seeds’ phytoconstituents on metabolic syndrome via in silico ...
  48. Lead optimization of Allium sativum L. compounds for PTP1B inhibition in diabetes treatment: in silico molecular docking and dynamics simulation
  49. Profiling the antidiabetic potential of GC–MS compounds identified from the methanolic extract of Spilanthes filicaulis : experimental and computational insight
  50. Atrazine exposure caused oxidative stress in male rats and inhibited brain‐pituitary‐testicular functions
  51. Therapeutic Study of Cinnamic Acid Derivative for Oxidative Stress Ablation: The Computational and Experimental Answers
  52. Antispasmodic Effect of Alstonia boonei De Wild. and Its Constituents: Ex Vivo and In Silico Approaches
  53. Diabetes mellitus: From molecular mechanism to pathophysiology and pharmacology
  54. Health and commercial relevance of Garcinia species: Key scientometric analyses from three decades of research
  55. Beet leaf (beta vulgaris L.) extract attenuates iron-induced testicular toxicity: Experimental and computational approach
  56. Pharmacological activities of Cissus populnea in human diseases
  57. Application and Acceptability of Microbiomes in the Production Process of Nigerian Indigenous Foods: Drive towards Responsible Production and Consumption
  58. Antidiabetic properties of Dioscoreophyllum cumminsii (Stapf) Diels stem bark on streptozotocin-induced diabetic rats
  59. In silico pharmacology and bioavailability of bioactive constituents from Triclisia subcordata (Oliv), an underutilized medicinal plant in Nigeria
  60. In silico modeling revealed phytomolecules derived from Cymbopogon citratus (DC.) leaf extract as promising candidates for malaria therapy
  61. Polyphenolic contents, free radical scavenging properties, and enzyme inhibitory activities of Acacia nilotica (L.) delile seed and pod extracts
  62. Therapeutic potential of rutin in male infertility: A mini review
  63. Apoptosis, inflammation, and oxidative stress in infertility: A mini review
  64. Antihypertensive activity of roasted cashew nut in mixed petroleum fractions-induced hypertension: An in vivo and in silico approaches
  65. Syzygium aromaticum (L.) Merr. & L.M.Perry mitigates iron-mediated oxidative brain injury via in vitro, ex vivo, and in silico approaches
  66. Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes
  67. Phytochemical properties and pharmacological activities of the genus Pennisetum: A review
  68. Kolaviron, A Biflavonoid Compound: Its Pharmacological Activity and Therapeutic Efficacy
  69. Occupational exposure in automobile repair workshops: toxicological effects of contaminated soil in Wistar rats
  70. Aqueous extract of Solanum macrocapon Linn leaf abate diabetic cardiomyopathy by attenuating oxidative stress and inflammation in rats
  71. Modulatory effect of fermented Tetracarpidium conophorum (African walnut) supplemented diet on cadmium-induced toxicity in rats
  72. Puerarin: A Review on the Pharmacological Activity, Chemical Properties and Pharmacokinetics of Main Isoflavonoid
  73. Computer aided and experimental study of cinnamic acid analog for oxidative stress treatment: The therapeutic validations
  74. Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy
  75. Biochemical evaluation and molecular docking assessment of Cymbopogon citratus as a natural source of acetylcholine esterase (AChE)- targeting insecticides
  76. Implications of Cannabis sativa on serotonin receptors 1B (HTR1B) and 7 (HTR7) genes in modulation of aggression and depression
  77. Gallic acid protects against cadmium chloride-induced alterations in Wistar rats via the antioxidant defense mechanism
  78. Novel ketogenic diet formulation improves sucrose‐induced insulin resistance in canton strain Drosophila melanogaster
  79. Contraceptive and biochemical effect of juice extract of Allium cepa , Allium sativum , and their combination in Canton S fruit flies
  80. Ameliorating activity of polyphenolic-rich extracts of Basella rubra L. leaves on pancreatic β-cell dysfunction in streptozotocin-induced diabetic rats
  81. Exploring the potentials of some compounds from Garcinia kola seeds towards identification of novel PDE‐5 inhibitors in erectile dysfunction therapy
  82. Protective impacts of gallic acid against cadmium-induced oxidative toxicity in the ovary of rats
  83. Deciphering the Interactions of Bioactive Compounds in Selected Traditional Medicinal Plants against Alzheimer’s Diseases via Pharmacophore Modeling, Auto-QSAR, and Molecular Docking Approaches
  84. Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats
  85. Deciphering the interactions of compounds from Allium sativum targeted towards identification of novel PTP 1B inhibitors in diabetes treatment: A computational approach
  86. Elucidating the interactions of compounds identified from Aframomum melegueta seeds as promising candidates for the management of diabetes mellitus: A computational approach
  87. Preclinical prediction of phytochemicals identified from cannabis as novel inhibitors of TEX 11, DHCR24, and CatSper 1 in fertility drug design
  88. Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats
  89. Deciphering the interaction of puerarin with cancer macromolecules: An in silico investigation
  90. Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids
  91. Effects of vitamin K dietary supplementation in pulmonary dysfunction induced by 7,12‐dimethylbenz[a]anthracene in rat
  92. Antioxidant and Inhibitory Activities of Enzymes Linked to Type II Diabetes Mellitus: The Novel Role of Chrysobalanus Orbicularis Leaf Extract
  93. Novel Coronavirus (SARS-CoV-2) Main Protease: Molecular docking of Puerarin as a Potential inhibitor
  94. Ameliorative effect of Gongronema latifolium leaf extract on alloxan-induced diabetic cardiomyopathy in Wistar rats model
  95. Gongronema latifolium Benth. leaf extract attenuates diabetes‐induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response
  96. Aqueous extract of Solanum macrocarpon Linn leaves abates hyperglycaemia and expression of glucose transporters gene in alloxan-induced diabetic rats
  97. Gongronema latifolium leaf extract modulates hyperglycaemia, inhibits redox imbalance and inflammation in alloxan-induced diabetic nephropathy
  98. Antioxidant activities of peptide hydrolysates obtained from the seeds of Treculia africana Decne (African breadfruit)
  99. In vitro antioxidant and enzyme inhibitory properties of the n-butanol fraction of Senna podocarpa (Guill. and Perr.) leaf
  100. Cnidoscolus aconitifolius (Mill.) I. M. Johnst leaf extract prevents oxidative hepatic injury and improves muscle glucose uptake ex vivo
  101. Effect of Glyphaea brevis twigs extract on cell viability, apoptosis induction and mitochondrial membrane potential in TM3 Leydig cells
  102. Protective effect of methanolic and flavonoid-rich leaf extracts of Synsepalum dulcificum (Danielli) on lead-acetate-induced toxicity in Wistar albino rats
  103. Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats
  104. Garcinia Kola Extracts Improve Biochemical Markers Associated with Erectile Function: Possible Applications in Clinical Treatment?
  105. Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with lead-induced oxidative stress
  106. Spondias mombim L. (Anacardiaceae): Chemical fingerprints, inhibitory activities, and molecular docking on key enzymes relevant to erectile dysfunction and Alzheimer’s diseases
  107. Effect of Zingiber officinale on some biochemical parameters and cytogenic analysis in lead-induced toxicity in experimental rats
  108. Antihyperlipidemic Activities and Hematological Properties of Ethanol Extract of Blighia Sapida Koenig Bark in Alloxan-induced Diabetic Rats
  109. Inhibitory effect of ethyl acetate fraction of Solanum macrocarpon L. leaves on cholinergic, monoaminergic, and purinergic enzyme activities
  110. In vitro antioxidant activities and inhibitory effects of phenolic extract of Senecio biafrae (Oliv and Hiern) against key enzymes linked with type II diabetes mellitus and Alzheimer's disease
  111. Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase
  112. Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme
  113. Inhibitory effect of aqueous extracts of raw and roasted Sesamum indicum L. seeds on key enzymes linked to type-2 diabetes (α-amylase and α-glucosidase) and Alzheimer’s disease (acetylcholinesterase and butyrylcholinesterase)
  114. Aqueous extract of Carica papaya Linn. roots potentially attenuates arsenic induced biochemical and genotoxic effects in Wistar rats
  115. Green-route mediated synthesis of silver nanoparticles (AgNPs) from Syzygium cumini (L.) Skeels polyphenolic-rich leaf extracts and investigation of their antimicrobial activity
  116. Ameliorative Activity of Ethanolic Extract of Artocarpus heterophyllus Stem Bark on Alloxan-induced Diabetic Rats
  117. Antioxidative Properties of Blighia sapida K.D. Koenig Stem Bark Extract and Inhibitory Effects on Carbohydrate Hydrolyzing Enzymes Associated with Non-Insulin Dependent Diabetes Mellitus
  118. Chromatographic fingerprint analysis, antioxidant properties, and inhibition of cholinergic enzymes (acetylcholinesterase and butyrylcholinesterase) of phenolic extracts from Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) Baill bark
  119. Characterization and Biological Activities of Biosynthesized Silver Nanoparticles from Stems of Blighia sapida K. D. Koenig
  120. Ethyl acetate leaf fraction of Cnidoscolus aconitifolius (Mill.) I. M. Johnst: antioxidant potential, inhibitory activities of key enzymes on carbohydrate metabolism, cholinergic, monoaminergic, purinergic, and chemical fingerprinting
  121. Anti-Hyperglycemic and Anti-Inflammatory Activities of Polyphenolic-Rich Extract of Syzygium cumini Linn Leaves in Alloxan-Induced Diabetic Rats
  122. HPLC-DAD fingerprinting analysis, antioxidant activities of Tithonia diversifolia (Hemsl.) A. Gray leaves and its inhibition of key enzymes linked to Alzheimer’s disease
  123. Aqueous Extract of Carica Papaya Linn Roots Halts Sodium Arsenite-Induced Renal Inflammation through Inhibiting Adenosine Deaminase, 8-Hydroxy-2′-Deoxyguanosine, C-Reactive Protein and Inducible Nitric Oxide Synthase Activity
  124. Modulatory Effect of Methanol Extract of Piper guineense in CCl4-Induced Hepatotoxicity in Male Rats
  125. Green Synthesis of Silver Nanoparticles (AgNPs) Using Talinum triangulare (Jacq.) Willd. Leaf Extract and Monitoring Their Antimicrobial Activity
  126. Biology of glucose metabolization in cancer cells
  127. Efficacy of Saponins From Helianthus annuus Roots on Antihyperglycemic, Antiperoxidative and Antihyperlipidemic Effects in Alloxan-Induced Diabetic Rats
  128. Ameliorative potential of Blighia sapida K.D. Koenig bark against pancreatic β-cell dysfunction in alloxan-induced diabetic rats
  129. Dennettia tripetala seeds inhibit ferrous sulphate-induced oxidative stress in rat tissues in vitro
  130. Ameliorative Activity of Ethanol Extract of Artocarpus heterophyllus Stem Bark on Pancreatic β-Cell Dysfunction in Alloxan-Induced Diabetic Rats
  131. Inhibitory Activity of Tithonia diversifolia (Hemsl.) A. Gray leaves on Some Pro-Oxidant Induced Oxidative Stress in Rat Brain
  132. Effect of rana galamensis–based diet on the activities of some enzymes and histopathology of selected tissues of albino rats
  133. Inhibitory effect on key enzymes relevant to acute type-2 diabetes and antioxidative activity of ethanolic extract of Artocarpus heterophyllus stem bark
  134. Nrf2-Keap1 Activation, A Promising Strategy in the Prevention of Cancer
  135. EXTRACTS OF OCIMUM GRATISSIMUM LEAVES INHIBITS FE2+ AND SODIUM NITROPRUSSIDE INDUCED OXIDATIVE STRESS IN RAT LIVER
  136. Helianthus annuus Leaf Ameliorates Postprandial Hyperglycaemia by Inhibiting Carbohydrate Hydrolyzing Enzymes Associated with Type-2 Diabetes
  137. Effect of Artocarpus altilis fruit based-diet on liver and kidney function indices on alloxan-induced diabetic rats
  138. Antioxidant and cardioprotective influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in Wistar rats
  139. Cardioprotective and antioxidant influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in wistar rats
  140. Cardioprotective and antioxidant influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in wistar rats
  141. Protective Influence of Ficus asperifolia Miq Leaf Extract on Carbon tetrachloride (CCL4)-Induced Testicular Toxicity in rat's Testes
  142. Ameliorative potential of Aframomum melegueta extract in cadmium-induced hepatic damage and oxidative stress in male Wistar rats
  143. Protective effect of Irvingia gabonensis stem bark extract on cadmiuminduced nephrotoxicity in rats
  144. HEMATOLOGICAL PROPERTIES OF IRVINGIA GABONENSIS
  145. Neuroprotective Mechanism of Ethanolic Extract of Irvingia gabonensis Stem Bark against Cadmium-induced Neurotoxicity in Rats
  146. Effects of Aqueous Extract of Ocimum gratissimum on Some Haematological Parameters of Albino Rats
  147. Neuroprotective effects of Alstonia boonei in rats
  148. Prophylactic Effects of Ethanolic Extract ofIrvingia gabonensisStem Bark against Cadmium-Induced Toxicity in Albino Rats
  149. Prophylactic effect of aqueous extract ofSesamum indicumseeds on ethanol-induced toxicity in male rats
  150. Toxicity Studies of the Crude Aqueous Leaves Extracts of Ocimum gratissimum in Albino Rats