All Stories

  1. Polyphenol-Rich Formulations and Their Multi-Target Interactions With Molecular Pathways in Cancer Cells
  2. Beyond traditional medicine: Erythrophyleum suaveolens (Guill. & Perr.) Brenan shows promising antidiabetic activity in experimentally induced type II diabetes
  3. Nrf-2/HO-1 modulatory effects on Ocimum gratissimum flavonoid-rich leaf extract in the livers of streptozotocin-induced diabetic rats
  4. Deciphering the mechanisms underlying the dual-target inhibition of carbohydrate-digesting and neurodegenerative enzymes by Syzygium aromaticum (L.) Merr. & L.M. via molecular docking and dynamics simulations
  5. Effects of <I>Celosia argentea</I> L. leaf on Monosodium Glutamate (MSG)-Induced Uterine Leiomyoma In Wistar Rats: Experimental and Computational Perspectives
  6. Evaluation of the ethanolic extract of Mondai whitei (Hook.f.) Skeels for their antioxidant, anti-inflammatory and antidiabetic properties
  7. Emerging trends in cancer biomarkers and their clinical effect on personalized treatment
  8. The Role of Dietary and Lifestyle Factors in the Formation of Premature Ovarian Insufficiency
  9. Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential
  10. Nutritional, antioxidant, enzyme inhibitory and toxicity assessments of an herbal formulation using in vitro, ex vivo, and in vivo approaches
  11. The UPR-oxidative stress nexus in diabetes and obesity: Exploring innovative therapeutic approaches for metabolic control
  12. Anti-breast cancer effects of Pterocarpus soyauxii Taub aqueous extract and its compounds by integrating ADMET, network pharmacology, molecular docking, dynamic simulation, CLC-Pred and pdCSM-Cancer/PPI approaches, and in vitro validation
  13. Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats
  14. Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies
  15. Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies
  16. Assessment of nutritional, antioxidant, and antidiabetic properties of the BF 1 herbal formulation via in vitro and ex vivo approaches
  17. Implications of plastic-derived endocrine disruptors on human health
  18. Antioxidant and antidiabetic activities of Gossypium barbadense L. leaves using in vitro, and in silico methods
  19. Interplay of the pathophysiological mechanisms of non-alcoholic fatty liver disease, diabetes mellitus, and inflammation: A growing threat to public health
  20. Protective effects of flavonoid-rich extracts from Hibiscus sabdariffa leaves on streptozotocin-induced testicular damage in rats
  21. Experimental and computational analyses of the anti-alzheimer and antidiabetic effects of flavonoid-rich extract of avocado seeds (Persea americana Mill.)
  22. Deciphering the in silico molecular mechanism of coumestrol activity for uterine fibroids remedy: a promising estrogenic target drug candidate
  23. Investigative assessment of the neuro-modulatory potentials of cannabichromene in TrkB/BDNF-mediated neurosignaling pathway
  24. Ferroptosis as the new approach to cancer therapy
  25. Albizia ferruginea (Guill. & Perr.) Benth. leaf abates deregulation of P53, IRS, HsD17β2, FTO, and CYP11a genes in polycystic ovarian syndrome rat
  26. Effect of Hibiscus sabdariffa L. leaf flavonoid-rich extract on Nrf-2 and HO-1 pathways in liver damage of streptozotocin-induced diabetic rats
  27. Energy metabolism and spermatogenesis
  28. Network Pharmacology, Molecular Dynamics and In Vitro Assessments of Indigenous Herbal Formulations for Alzheimer’s Therapy
  29. Oxidative Stress-induced Hormonal Disruption in Male Reproduction
  30. Petiveria alliacea L. extract protects against streptozotocin-induced type-2 diabetes by modulating the cAMP/PKA/CREB/cFOS pathway
  31. Studies on melatonin intervention in reactive oxygen species-linked autophagy of neocarzinostatin-induced varicocele infertility in male Swiss Albino mice
  32. Preclinical antidiabetic and antioxidant effects of Erythrophleum africanum (benth.) harms in streptozotocin-induced diabetic nephropathy
  33. Attenuation of PI3K/AKT signaling pathway by Ocimum gratissimum leaf flavonoid-rich extracts in streptozotocin-induced diabetic male rats
  34. Mitophagy and spermatogenesis: Role and mechanisms
  35. Spilanthes filicaulis (Schumach. & Thonn.) C. D Adam leaf extract prevents assault of streptozotocin on liver cells via inhibition of oxidative stress and activation of the NrF2/Keap1, PPARγ, and PTP1B signaling pathways
  36. Ocimum gratissimum L. leaf flavonoid-rich extracts reduced the expression of p53 and VCAM in streptozotocin-induced cardiomyopathy rats
  37. Spilanthes filicaulis (Schumach. & Thonn.) C.D. Adams leaves protects against streptozotocin-induced diabetic nephropathy
  38. Kigelia africana (Lam.) Benth. fruit inhibits iron-induced lipid peroxidation and ?-amylase enzyme activity
  39. Production, acceptability, nutritional and pasting properties of orange-flesh sweet potato, cowpea and banana flour mix
  40. Alkaloid-rich extract of Lannea egregia leaf protect against cardiomyopathy in streptozotocin-induced type 2 diabetic rats
  41. Exploring beetroot (Beta vulgaris L.) for diabetes mellitus and Alzheimer's disease dual therapy: in vitro and computational studies
  42. Elemental evaluation, nutritional analysis, GC-MS analysis and ameliorative effects of Artocarpus communis J.R.Forst. & G.Forst. seeds’ phytoconstituents on metabolic syndrome via in silico ...
  43. Lead optimization of Allium sativum L. compounds for PTP1B inhibition in diabetes treatment: in silico molecular docking and dynamics simulation
  44. Profiling the antidiabetic potential of GC–MS compounds identified from the methanolic extract of Spilanthes filicaulis : experimental and computational insight
  45. Atrazine exposure caused oxidative stress in male rats and inhibited brain‐pituitary‐testicular functions
  46. Therapeutic Study of Cinnamic Acid Derivative for Oxidative Stress Ablation: The Computational and Experimental Answers
  47. Antispasmodic Effect of Alstonia boonei De Wild. and Its Constituents: Ex Vivo and In Silico Approaches
  48. Diabetes mellitus: From molecular mechanism to pathophysiology and pharmacology
  49. Health and commercial relevance of Garcinia species: Key scientometric analyses from three decades of research
  50. Beet leaf (beta vulgaris L.) extract attenuates iron-induced testicular toxicity: Experimental and computational approach
  51. Pharmacological activities of Cissus populnea in human diseases
  52. Application and Acceptability of Microbiomes in the Production Process of Nigerian Indigenous Foods: Drive towards Responsible Production and Consumption
  53. Antidiabetic properties of Dioscoreophyllum cumminsii (Stapf) Diels stem bark on streptozotocin-induced diabetic rats
  54. In silico pharmacology and bioavailability of bioactive constituents from Triclisia subcordata (Oliv), an underutilized medicinal plant in Nigeria
  55. In silico modeling revealed phytomolecules derived from Cymbopogon citratus (DC.) leaf extract as promising candidates for malaria therapy
  56. Polyphenolic contents, free radical scavenging properties, and enzyme inhibitory activities of Acacia nilotica (L.) delile seed and pod extracts
  57. Therapeutic potential of rutin in male infertility: A mini review
  58. Apoptosis, inflammation, and oxidative stress in infertility: A mini review
  59. Antihypertensive activity of roasted cashew nut in mixed petroleum fractions-induced hypertension: An in vivo and in silico approaches
  60. Syzygium aromaticum (L.) Merr. & L.M.Perry mitigates iron-mediated oxidative brain injury via in vitro, ex vivo, and in silico approaches
  61. Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes
  62. Phytochemical properties and pharmacological activities of the genus Pennisetum: A review
  63. Kolaviron, A Biflavonoid Compound: Its Pharmacological Activity and Therapeutic Efficacy
  64. Occupational exposure in automobile repair workshops: toxicological effects of contaminated soil in Wistar rats
  65. Aqueous extract of Solanum macrocapon Linn leaf abate diabetic cardiomyopathy by attenuating oxidative stress and inflammation in rats
  66. Modulatory effect of fermented Tetracarpidium conophorum (African walnut) supplemented diet on cadmium-induced toxicity in rats
  67. Puerarin: A Review on the Pharmacological Activity, Chemical Properties and Pharmacokinetics of Main Isoflavonoid
  68. Computer aided and experimental study of cinnamic acid analog for oxidative stress treatment: The therapeutic validations
  69. Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy
  70. Biochemical evaluation and molecular docking assessment of Cymbopogon citratus as a natural source of acetylcholine esterase (AChE)- targeting insecticides
  71. Implications of Cannabis sativa on serotonin receptors 1B (HTR1B) and 7 (HTR7) genes in modulation of aggression and depression
  72. Gallic acid protects against cadmium chloride-induced alterations in Wistar rats via the antioxidant defense mechanism
  73. Novel ketogenic diet formulation improves sucrose‐induced insulin resistance in canton strain Drosophila melanogaster
  74. Contraceptive and biochemical effect of juice extract of Allium cepa , Allium sativum , and their combination in Canton S fruit flies
  75. Ameliorating activity of polyphenolic-rich extracts of Basella rubra L. leaves on pancreatic β-cell dysfunction in streptozotocin-induced diabetic rats
  76. Exploring the potentials of some compounds from Garcinia kola seeds towards identification of novel PDE‐5 inhibitors in erectile dysfunction therapy
  77. Protective impacts of gallic acid against cadmium-induced oxidative toxicity in the ovary of rats
  78. Deciphering the Interactions of Bioactive Compounds in Selected Traditional Medicinal Plants against Alzheimer’s Diseases via Pharmacophore Modeling, Auto-QSAR, and Molecular Docking Approaches
  79. Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats
  80. Deciphering the interactions of compounds from Allium sativum targeted towards identification of novel PTP 1B inhibitors in diabetes treatment: A computational approach
  81. Elucidating the interactions of compounds identified from Aframomum melegueta seeds as promising candidates for the management of diabetes mellitus: A computational approach
  82. Preclinical prediction of phytochemicals identified from cannabis as novel inhibitors of TEX 11, DHCR24, and CatSper 1 in fertility drug design
  83. Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats
  84. Deciphering the interaction of puerarin with cancer macromolecules: An in silico investigation
  85. Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids
  86. Effects of vitamin K dietary supplementation in pulmonary dysfunction induced by 7,12‐dimethylbenz[a]anthracene in rat
  87. Antioxidant and Inhibitory Activities of Enzymes Linked to Type II Diabetes Mellitus: The Novel Role of Chrysobalanus Orbicularis Leaf Extract
  88. Novel Coronavirus (SARS-CoV-2) Main Protease: Molecular docking of Puerarin as a Potential inhibitor
  89. Ameliorative effect of Gongronema latifolium leaf extract on alloxan-induced diabetic cardiomyopathy in Wistar rats model
  90. Gongronema latifolium Benth. leaf extract attenuates diabetes‐induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response
  91. Aqueous extract of Solanum macrocarpon Linn leaves abates hyperglycaemia and expression of glucose transporters gene in alloxan-induced diabetic rats
  92. Gongronema latifolium leaf extract modulates hyperglycaemia, inhibits redox imbalance and inflammation in alloxan-induced diabetic nephropathy
  93. Antioxidant activities of peptide hydrolysates obtained from the seeds of Treculia africana Decne (African breadfruit)
  94. In vitro antioxidant and enzyme inhibitory properties of the n-butanol fraction of Senna podocarpa (Guill. and Perr.) leaf
  95. Cnidoscolus aconitifolius (Mill.) I. M. Johnst leaf extract prevents oxidative hepatic injury and improves muscle glucose uptake ex vivo
  96. Effect of Glyphaea brevis twigs extract on cell viability, apoptosis induction and mitochondrial membrane potential in TM3 Leydig cells
  97. Protective effect of methanolic and flavonoid-rich leaf extracts of Synsepalum dulcificum (Danielli) on lead-acetate-induced toxicity in Wistar albino rats
  98. Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats
  99. Garcinia Kola Extracts Improve Biochemical Markers Associated with Erectile Function: Possible Applications in Clinical Treatment?
  100. Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with lead-induced oxidative stress
  101. Spondias mombim L. (Anacardiaceae): Chemical fingerprints, inhibitory activities, and molecular docking on key enzymes relevant to erectile dysfunction and Alzheimer’s diseases
  102. Effect of Zingiber officinale on some biochemical parameters and cytogenic analysis in lead-induced toxicity in experimental rats
  103. Antihyperlipidemic Activities and Hematological Properties of Ethanol Extract of Blighia Sapida Koenig Bark in Alloxan-induced Diabetic Rats
  104. Inhibitory effect of ethyl acetate fraction of Solanum macrocarpon L. leaves on cholinergic, monoaminergic, and purinergic enzyme activities
  105. In vitro antioxidant activities and inhibitory effects of phenolic extract of Senecio biafrae (Oliv and Hiern) against key enzymes linked with type II diabetes mellitus and Alzheimer's disease
  106. Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase
  107. Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme
  108. Inhibitory effect of aqueous extracts of raw and roasted Sesamum indicum L. seeds on key enzymes linked to type-2 diabetes (α-amylase and α-glucosidase) and Alzheimer’s disease (acetylcholinesterase and butyrylcholinesterase)
  109. Aqueous extract of Carica papaya Linn. roots potentially attenuates arsenic induced biochemical and genotoxic effects in Wistar rats
  110. Green-route mediated synthesis of silver nanoparticles (AgNPs) from Syzygium cumini (L.) Skeels polyphenolic-rich leaf extracts and investigation of their antimicrobial activity
  111. Ameliorative Activity of Ethanolic Extract of Artocarpus heterophyllus Stem Bark on Alloxan-induced Diabetic Rats
  112. Antioxidative Properties of Blighia sapida K.D. Koenig Stem Bark Extract and Inhibitory Effects on Carbohydrate Hydrolyzing Enzymes Associated with Non-Insulin Dependent Diabetes Mellitus
  113. Chromatographic fingerprint analysis, antioxidant properties, and inhibition of cholinergic enzymes (acetylcholinesterase and butyrylcholinesterase) of phenolic extracts from Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) Baill bark
  114. Characterization and Biological Activities of Biosynthesized Silver Nanoparticles from Stems of Blighia sapida K. D. Koenig
  115. Ethyl acetate leaf fraction of Cnidoscolus aconitifolius (Mill.) I. M. Johnst: antioxidant potential, inhibitory activities of key enzymes on carbohydrate metabolism, cholinergic, monoaminergic, purinergic, and chemical fingerprinting
  116. Anti-Hyperglycemic and Anti-Inflammatory Activities of Polyphenolic-Rich Extract of Syzygium cumini Linn Leaves in Alloxan-Induced Diabetic Rats
  117. HPLC-DAD fingerprinting analysis, antioxidant activities of Tithonia diversifolia (Hemsl.) A. Gray leaves and its inhibition of key enzymes linked to Alzheimer’s disease
  118. Aqueous Extract of Carica Papaya Linn Roots Halts Sodium Arsenite-Induced Renal Inflammation through Inhibiting Adenosine Deaminase, 8-Hydroxy-2′-Deoxyguanosine, C-Reactive Protein and Inducible Nitric Oxide Synthase Activity
  119. Modulatory Effect of Methanol Extract of Piper guineense in CCl4-Induced Hepatotoxicity in Male Rats
  120. Green Synthesis of Silver Nanoparticles (AgNPs) Using Talinum triangulare (Jacq.) Willd. Leaf Extract and Monitoring Their Antimicrobial Activity
  121. Biology of glucose metabolization in cancer cells
  122. Efficacy of Saponins From Helianthus annuus Roots on Antihyperglycemic, Antiperoxidative and Antihyperlipidemic Effects in Alloxan-Induced Diabetic Rats
  123. Ameliorative potential of Blighia sapida K.D. Koenig bark against pancreatic β-cell dysfunction in alloxan-induced diabetic rats
  124. Dennettia tripetala seeds inhibit ferrous sulphate-induced oxidative stress in rat tissues in vitro
  125. Ameliorative Activity of Ethanol Extract of Artocarpus heterophyllus Stem Bark on Pancreatic β-Cell Dysfunction in Alloxan-Induced Diabetic Rats
  126. Inhibitory Activity of Tithonia diversifolia (Hemsl.) A. Gray leaves on Some Pro-Oxidant Induced Oxidative Stress in Rat Brain
  127. Effect of rana galamensis–based diet on the activities of some enzymes and histopathology of selected tissues of albino rats
  128. Inhibitory effect on key enzymes relevant to acute type-2 diabetes and antioxidative activity of ethanolic extract of Artocarpus heterophyllus stem bark
  129. Nrf2-Keap1 Activation, A Promising Strategy in the Prevention of Cancer
  130. EXTRACTS OF OCIMUM GRATISSIMUM LEAVES INHIBITS FE2+ AND SODIUM NITROPRUSSIDE INDUCED OXIDATIVE STRESS IN RAT LIVER
  131. Helianthus annuus Leaf Ameliorates Postprandial Hyperglycaemia by Inhibiting Carbohydrate Hydrolyzing Enzymes Associated with Type-2 Diabetes
  132. Effect of Artocarpus altilis fruit based-diet on liver and kidney function indices on alloxan-induced diabetic rats
  133. Antioxidant and cardioprotective influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in Wistar rats
  134. Cardioprotective and antioxidant influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in wistar rats
  135. Cardioprotective and antioxidant influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in wistar rats
  136. Protective Influence of Ficus asperifolia Miq Leaf Extract on Carbon tetrachloride (CCL4)-Induced Testicular Toxicity in rat's Testes
  137. Ameliorative potential of Aframomum melegueta extract in cadmium-induced hepatic damage and oxidative stress in male Wistar rats
  138. Protective effect of Irvingia gabonensis stem bark extract on cadmiuminduced nephrotoxicity in rats
  139. HEMATOLOGICAL PROPERTIES OF IRVINGIA GABONENSIS
  140. Neuroprotective Mechanism of Ethanolic Extract of Irvingia gabonensis Stem Bark against Cadmium-induced Neurotoxicity in Rats
  141. Effects of Aqueous Extract of Ocimum gratissimum on Some Haematological Parameters of Albino Rats
  142. Neuroprotective effects of Alstonia boonei in rats
  143. Prophylactic Effects of Ethanolic Extract ofIrvingia gabonensisStem Bark against Cadmium-Induced Toxicity in Albino Rats
  144. Prophylactic effect of aqueous extract ofSesamum indicumseeds on ethanol-induced toxicity in male rats
  145. Toxicity Studies of the Crude Aqueous Leaves Extracts of Ocimum gratissimum in Albino Rats