All Stories

  1. An EOMES induced epigenetic deflection initiates lineage commitment at mammalian gastrulation

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  2. Neoadjuvant Chemotherapy or Combined Chemo-Radiation Therapy of Pancreatic Ductal Adenocarcinoma Differentially Shift Immune Activation, ECM Composition, Energy Metabolism, and Ribosomal Proteins of the Residual Tumor Mass

    Article • March 2023, Research Square

    Dr Oliver Schilling

  3. Characterization of Spatial Heterogeneity in Metastasized Colorectal Cancer by MALDI Imaging

    Article • February 2023, MDPI AG

    Dr Oliver Schilling

  4. Targeted and explorative profiling of kallikrein proteases and global proteome biology of pancreatic ductal adenocarcinoma, chronic pancreatitis, and normal pancreas highlights disease-specific proteome remodelling

    Article • Neoplasia, February 2023, Elsevier

    Dr Oliver Schilling

  5. Proteome-Wide Identification of RNA-Dependent Proteins in Lung Cancer Cells

    Article • Cancers, December 2022, MDPI AG

    Dr Oliver Schilling

  6. Targeted and Explorative Profiling of Kallikrein Proteases and Global Proteome Biology of Pancreatic Ductal Adenocarcinoma, Chronic Pancreatitis, and Normal Pancreas Highlights Disease-Specific Proteome Remodelling

    Article • November 2022, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  7. Proteome alterations during clonal isolation of established human pancreatic cancer cell lines

    Article • Cellular and Molecular Life Sciences, October 2022, Springer Science + Business Media

    Dr Oliver Schilling

  8. Addition of Chromosome 17 Polysomy and HER2 Amplification Status Improves the Accuracy of Clinicopathological Factor-Based Progression Risk Stratification and Tumor Grading of Non-Muscle-Invasive Bladder Cancer

    Article • Cancers, September 2022, MDPI AG

    Dr Oliver Schilling

  9. MaxQuant and MSstats in Galaxy Enable Reproducible Cloud-Based Analysis of Quantitative Proteomics Experiments for Everyone

    Article • Journal of Proteome Research, May 2022, American Chemical Society (ACS)

    Dr Oliver Schilling

  10. NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes

    Article • Cells, April 2022, MDPI AG

    Dr Oliver Schilling

  11. MaxQuant and MSstats in Galaxy enable reproducible cloud-based analysis of quantitative proteomics experiments for everyone

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  12. An adapted passive model of anti-MPO dependent crescentic glomerulonephritis reveals matrix dysregulation and is amenable to modulation by CXCR4 inhibition

    Article • Matrix Biology, January 2022, Elsevier

    Dr Oliver Schilling

  13. Democratizing data-independent acquisition proteomics analysis on public cloud infrastructures via the Galaxy framework

    Article • GigaScience, January 2022, Oxford University Press (OUP)

    Dr Oliver Schilling

  14. Proteome biology of primary colorectal carcinoma and corresponding liver metastases

    Article • Neoplasia, December 2021, Elsevier

    Dr Oliver Schilling

  15. Proteome biology of primary colorectal carcinoma and corresponding liver metastases

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  16. Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: A case study of an urothelial cancer cohort analyzed in the Galaxy framework

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  17. Democratizing Data-Independent Acquisition Proteomics Analysis on Public Cloud Infrastructures Via The Galaxy Framework

    Article • July 2021, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  18. A Systematic Evaluation of Semispecific Peptide Search Parameter Enables Identification of Previously Undescribed N-Terminal Peptides and Conserved Proteolytic Processing in Cancer Cell Lines

    Article • Proteomes, May 2021, MDPI AG

    Dr Oliver Schilling

  19. EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission

    Article • Cell Reports, March 2021, Elsevier

    Dr Oliver Schilling

  20. Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells

    Article • Cells, February 2021, MDPI AG

    Dr Oliver Schilling

  21. Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage

    Article • International Journal of Molecular Sciences, February 2021, MDPI AG

    Dr Oliver Schilling

  22. Automation of peptide desalting for proteomic liquid chromatography – tandem mass spectrometry by centrifugal microfluidics

    Article • Lab on a Chip, January 2021, Royal Society of Chemistry

    Dr Oliver Schilling

  23. Discovery of a novel small protein factor involved in the coordinated degradation of phycobilisomes in cyanobacteria

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling

  24. Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death

    Article • Cancer Cell International, February 2020, Springer Science + Business Media

    Dr Oliver Schilling

  25. Accessible and reproducible mass spectrometry imaging data analysis in Galaxy

    Article • GigaScience, December 2019, Oxford University Press (OUP)

    Dr Oliver Schilling, Björn Grüning

  26. Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine

    Article • Metabolites, October 2019, MDPI AG

    Dr Oliver Schilling

  27. Impact of left ventricular assist device therapy on the cardiac proteome and metabolome composition in ischemic cardiomyopathy

    Article • Artificial Organs, October 2019, Wiley

    Dr Oliver Schilling

  28. Neuronal-specific microexon splicing of TAF1 mRNA is directly regulated by SRRM4/nSR100

    Article • RNA Biology, September 2019, Taylor & Francis

    Dr Oliver Schilling

  29. A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins

    Article • Mobile DNA, August 2019, Springer Science + Business Media

    Dr Oliver Schilling

  30. Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome

    Article • Journal of Cellular and Molecular Medicine, July 2019, Wiley

    Dr Oliver Schilling

  31. Detection and Characterization of a Mycobacterial L-Arabinofuranose ABC Transporter Identified with a Rapid Lipoproteomics Protocol

    Article • Cell Chemical Biology, June 2019, Elsevier

    Dr Oliver Schilling

  32. Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer

    Article • Cell, June 2019, Elsevier

    Dr Oliver Schilling

  33. Accessible and reproducible mass spectrometry imaging data analysis in Galaxy

    Article • May 2019, Cold Spring Harbor Laboratory Press

    Dr Oliver Schilling, Björn Grüning

  34. Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics

    Article • Biomaterials, February 2019, Elsevier

    Dr Oliver Schilling

  35. ADAM9 contributes to vascular invasion in pancreatic ductal adenocarcinoma

    Article • Molecular Oncology, January 2019, Wiley

    Dr Oliver Schilling

  36. Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways

    Article • Cellular Microbiology, January 2019, Wiley

    Dr Oliver Schilling

  37. Radiomic features from PSMA PET for non-invasive intraprostatic tumor discrimination and characterization in patients with intermediate- and high-risk prostate cancer - a comparison study with histology reference

    Article • Theranostics, January 2019, Ivyspring International Publisher

    Dr Oliver Schilling

  38. FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus

    Article • Molecular Neurobiology, December 2018, Springer Science + Business Media

    Dr Oliver Schilling

  39. Proteome Profiling of Primary Pancreatic Ductal Adenocarcinomas Undergoing Additive Chemoradiation Link ALDH1A1 to Early Local Recurrence and Chemoradiation Resistance

    Article • Translational Oncology, December 2018, Elsevier

    Dr Oliver Schilling

  40. Dreidimensionale Rekonstruktion solider Tumoren

    Article • Der Pathologe, October 2018, Springer Science + Business Media

    Dr Oliver Schilling

  41. Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer

    Article • British Journal of Cancer, October 2018, Springer Science + Business Media

    Dr Oliver Schilling

  42. Multimodal imaging for radiation therapy planning in patients with primary prostate cancer

    Article • Physics and Imaging in Radiation Oncology, October 2018, Elsevier

    Dr Oliver Schilling

  43. Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics

    Article • Molecular & Cellular Proteomics, September 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  44. The two cathepsin B-like proteases of Arabidopsis thaliana are closely related enzymes with discrete endopeptidase and carboxydipeptidase activities

    Article • Biological Chemistry, September 2018, De Gruyter

    Dr Oliver Schilling

  45. Specificity profiling of human trypsin-isoenzymes

    Article • Biological Chemistry, September 2018, De Gruyter

    Dr Oliver Schilling

  46. N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration

    Article • Matrix Biology, September 2018, Elsevier

    Dr Oliver Schilling

  47. Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

    Article • Nature Communications, August 2018, Springer Science + Business Media

    Dr Oliver Schilling

  48. Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas

    Article • Clinical Proteomics, August 2018, Springer Science + Business Media

    Dr Oliver Schilling

  49. Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin

    Article • Scientific Reports, July 2018, Springer Science + Business Media

    Dr Oliver Schilling

  50. Nanoparticle decoration impacts airborne fungal pathobiology

    Article • Proceedings of the National Academy of Sciences, June 2018, Proceedings of the National Academy of Sciences

    Dr Oliver Schilling

  51. Morphology of Immunomodulation in Breast Cancer Tumor Draining Lymph Nodes Depends on Stage and Intrinsic Subtype

    Article • Scientific Reports, March 2018, Springer Science + Business Media

    Dr Oliver Schilling

  52. The pleiotropic roles of ADAM9 in the biology of solid tumors

    Article • Cellular and Molecular Life Sciences, March 2018, Springer Science + Business Media

    Dr Oliver Schilling

  53. Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization

    Article • Clinical Proteomics, March 2018, Springer Science + Business Media

    Dr Oliver Schilling

  54. Identification of tissue damage, extracellular matrix remodeling and bacterial challenge as common mechanisms associated with high-risk cutaneous squamous cell carcinomas

    Article • Matrix Biology, March 2018, Elsevier

    Dr Oliver Schilling

  55. Proteomic Characterization of Prostate Cancer to Distinguish Nonmetastasizing and Metastasizing Primary Tumors and Lymph Node Metastases

    Article • Neoplasia, February 2018, Elsevier

    Dr Oliver Schilling

  56. HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model

    Article • EBioMedicine, January 2018, Elsevier

    Dr Oliver Schilling, Thomas Burgoyne

  57. The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton

    Article • Scientific Reports, November 2017, Springer Science + Business Media

    Dr Oliver Schilling

  58. HtrA1 activation is driven by an allosteric mechanism of inter-monomer communication

    Article • Scientific Reports, November 2017, Springer Science + Business Media

    Dr Oliver Schilling

  59. OpenMS – A platform for reproducible analysis of mass spectrometry data

    Article • Journal of Biotechnology, November 2017, Elsevier

    Dr Oliver Schilling

  60. Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an anti-proliferative and anti-migratory exoprotease

    Article • Oncotarget, October 2017, Impact Journals, LLC

    Dr Oliver Schilling

  61. Differential effect of TGFβ on the proteome of cancer associated fibroblasts and cancer epithelial cells in a co-culture approach - a short report

    Article • Cellular Oncology, August 2017, Springer Science + Business Media

    Dr Oliver Schilling

  62. Determinants of Macromolecular Specificity from Proteomics-De rived Peptide Substrate Data

    Article • Current Protein and Peptide Science, July 2017, Bentham Science Publishers

    Dr Oliver Schilling

  63. Form follows function: Morphological and immunohistological insights into epithelial–mesenchymal transition characteristics of tumor buds

    Article • Tumor Biology, May 2017, SAGE Publications

    Dr Oliver Schilling

  64. The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, April 2017, Elsevier

    Dr Oliver Schilling

  65. Proteomics highlights decrease of matricellular proteins in left ventricular assist device therapy†

    Article • European Journal of Cardio-Thoracic Surgery, February 2017, Oxford University Press (OUP)

    Dr Oliver Schilling

  66. Identification of Protease Cleavage Sites by Charge-Based Enrichment of Protein N-Termini

    Article • January 2017, Springer Science + Business Media

    Dr Oliver Schilling

  67. Profiling of Protease Cleavage Sites by Proteome-Derived Peptide Libraries and Quantitative Proteomics

    Article • January 2017, Springer Science + Business Media

    Dr Oliver Schilling

  68. Proteomic analysis of lung metastases in a murine breast cancer model reveals divergent influence of CTSB and CTSL overexpression

    Article • Journal of Cancer, January 2017, Ivyspring International Publisher

    Dr Oliver Schilling

  69. System-Wide Profiling of Protein Amino Termini from Formalin-Fixed, Paraffin-Embedded Tissue Specimens for the Identification of Novel Substrates

    Article • January 2017, Springer Science + Business Media

    Dr Oliver Schilling

  70. The Prognostic Impact of the Carcinoembryonic Antigen in Ampullary Cancer - A Retrospective Single Center Study

    Article • Journal of Cancer, January 2017, Ivyspring International Publisher

    Dr Oliver Schilling

  71. Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling

    Article • Cell Reports, December 2016, Elsevier

    Dr Oliver Schilling

  72. Proteomic analysis of silenced cathepsin B expression suggests non-proteolytic cathepsin B functionality

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, November 2016, Elsevier

    Dr Oliver Schilling

  73. Yeast membrane proteomics using leucine metabolic labelling: Bioinformatic data processing and exemplary application to the ER-intramembrane protease Ypf1

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, October 2016, Elsevier

    Dr Oliver Schilling

  74. OpenMS: a flexible open-source software platform for mass spectrometry data analysis

    Article • Nature Methods, August 2016, Springer Science + Business Media

    Dr Oliver Schilling

  75. The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity

    Article • Archives of Biochemistry and Biophysics, August 2016, Elsevier

    Dr Oliver Schilling

  76. Proteomic Profiling of Cardiomyocyte-Specific Cathepsin A Overexpression Links Cathepsin A to the Oxidative Stress Response

    Article • Journal of Proteome Research, July 2016, American Chemical Society (ACS)

    Dr Oliver Schilling

  77. Comprehensive Proteomic Analysis of Nitrogen-Starved Mycobacterium smegmatis Δpup Reveals the Impact of Pupylation on Nitrogen Stress Response

    Article • Journal of Proteome Research, July 2016, American Chemical Society (ACS)

    Dr Oliver Schilling

  78. Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14

    Article • Data in Brief, June 2016, Elsevier

    Dr Oliver Schilling

  79. Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels

    Article • Journal of Translational Medicine, May 2016, Springer Science + Business Media

    Dr Oliver Schilling

  80. Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics

    Article • Molecular & Cellular Proteomics, April 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  81. Skin Barrier Defects Caused by Keratinocyte-Specific Deletion of ADAM17 or EGFR Are Based on Highly Similar Proteome and Degradome Alterations

    Article • Journal of Proteome Research, April 2016, American Chemical Society (ACS)

    Dr Oliver Schilling

  82. Formalin-Fixed, Paraffin-Embedded Tissues (FFPE) as a Robust Source for the Profiling of Native and Protease-Generated Protein Amino Termini

    Article • Molecular & Cellular Proteomics, April 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  83. Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses

    Article • BMC Cancer, March 2016, Springer Science + Business Media

    Dr Oliver Schilling

  84. Impact of cathepsin B on the interstitial fluid proteome of murine breast cancers

    Article • Biochimie, March 2016, Elsevier

    Dr Oliver Schilling

  85. Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses

    Article • Matrix Biology, January 2016, Elsevier

    Dr Oliver Schilling

  86. Mesopancreatic Stromal Clearance Defines Curative Resection of Pancreatic Head Cancer and Can Be Predicted Preoperatively by Radiologic Parameters

    Article • Medicine, January 2016, Wolters Kluwer Health

    Dr Oliver Schilling

  87. Pregnancy Specific β-1 Glycoprotein 1 is Expressed in Pancreatic Ductal Adenocarcinoma and its Subcellular Localization Correlates with Overall Survival

    Article • Journal of Cancer, January 2016, Ivyspring International Publisher

    Dr Oliver Schilling

  88. Taspase1: a 'misunderstood' protease with translational cancer relevance

    Article • Oncogene, December 2015, Springer Science + Business Media

    Dr Oliver Schilling

  89. A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity

    Article • Journal of Biological Chemistry, November 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  90. An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation

    Article • Cell Reports, October 2015, Elsevier

    Dr Oliver Schilling

  91. The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2015, Elsevier

    Dr Oliver Schilling

  92. Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations

    Article • Molecular Oncology, August 2015, Wiley

    Dr Oliver Schilling

  93. Quantitative proteomic analysis of formalin–fixed, paraffin–embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines

    Article • BMC Genomics, July 2015, Springer Science + Business Media

    Dr Oliver Schilling

  94. Toward improved peptide feature detection in quantitative proteomics using stable isotope labeling

    Article • PROTEOMICS - CLINICAL APPLICATIONS, July 2015, Wiley

    Dr Oliver Schilling

  95. miR-200c dampens cancer cell migration via regulation of protein kinase A subunits

    Article • Oncotarget, June 2015, Impact Journals, LLC

    Dr Oliver Schilling

  96. Enrichment of protein N-termini by charge reversal of internal peptides

    Article • PROTEOMICS, June 2015, Wiley

    Dr Oliver Schilling

  97. The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells

    Article • Neuro-Oncology, March 2015, Oxford University Press (OUP)

    Dr Oliver Schilling

  98. The emerging role of the peptidome in biomarker discovery and degradome profiling

    Article • Biological Chemistry, March 2015, De Gruyter

    Dr Oliver Schilling

  99. Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma

    Article • Journal of Gastroenterology and Hepatology, March 2015, Wiley

    Dr Oliver Schilling

  100. Protein amino-terminal modifications and proteomic approaches for N-terminal profiling

    Article • Current Opinion in Chemical Biology, February 2015, Elsevier

    Dr Oliver Schilling

  101. Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells

    Article • Molecular Cancer, January 2015, Springer Science + Business Media

    Dr Oliver Schilling

  102. Evolutionary divergence of Threonine Aspartase1 leads to species-specific substrate recognition

    Article • Biological Chemistry, January 2015, De Gruyter

    Dr Oliver Schilling

  103. The Yeast ER-Intramembrane Protease Ypf1 Refines Nutrient Sensing by Regulating Transporter Abundance

    Article • Molecular Cell, December 2014, Elsevier

    Dr Oliver Schilling

  104. Carboxyterminal Protein Processing in Health and Disease: Key Actors and Emerging Technologies

    Article • Journal of Proteome Research, November 2014, American Chemical Society (ACS)

    Dr Oliver Schilling

  105. Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface

    Article • The Journal of Pathology, October 2014, Wiley

    Dr Oliver Schilling

  106. Septins Arrange F-Actin-Containing Fibers on the Chlamydia trachomatis Inclusion and Are Required for Normal Release of the Inclusion by Extrusion

    Article • mBio, October 2014, ASM Journals

    Dr Oliver Schilling

  107. Impact of routinely employed procedures for tissue processing on the proteomic analysis of formalin-fixed paraffin-embedded tissue

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2014, Wiley

    Dr Oliver Schilling

  108. Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer

    Article • Surgery, July 2014, Elsevier

    Dr Oliver Schilling

  109. Proteases and Disease

    Article • PROTEOMICS - CLINICAL APPLICATIONS, June 2014, Wiley

    Dr Oliver Schilling

  110. Global remodelling of cellular microenvironment due to loss of collagen VII

    Article • Molecular Systems Biology, April 2014, EMBO

    Dr Oliver Schilling

  111. Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapy

    Article • PROTEOMICS - CLINICAL APPLICATIONS, March 2014, Wiley

    Dr Oliver Schilling

  112. Transmembrane Collagen XVII Modulates Integrin Dependent Keratinocyte Migration via PI3K/Rac1 Signaling

    Article • PLoS ONE, February 2014, PLOS

    Dr Oliver Schilling

  113. Automated peptide mapping and protein-topographical annotation of proteomics data

    Article • BMC Bioinformatics, January 2014, Springer Science + Business Media

    Dr Oliver Schilling

  114. Proteomic identification of protease cleavage sites: cell-biological and biomedical applications

    Article • Expert Review of Proteomics, October 2013, Taylor & Francis

    Dr Oliver Schilling

  115. Secretome and degradome profiling shows that Kallikrein-related peptidases 4, 5, 6, and 7 induce TGFβ-1 signaling in ovarian cancer cells

    Article • Molecular Oncology, October 2013, Wiley

    Dr Oliver Schilling

  116. Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis

    Article • Cellular and Molecular Life Sciences, June 2013, Springer Science + Business Media

    Dr Oliver Schilling

  117. Glycocapture-based proteomics for secretome analysis

    Article • PROTEOMICS, January 2013, Wiley

    Dr Oliver Schilling

  118. Limited and Degradative Proteolysis in the Context of Posttranslational Regulatory Networks: Current Technical and Conceptional Advances

    Article • January 2013, Springer Science + Business Media

    Dr Oliver Schilling

  119. Deletion of Cysteine Cathepsins B or L Yields Differential Impacts on Murine Skin Proteome and Degradome

    Article • Molecular & Cellular Proteomics, December 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  120. Enhanced identification of peptides lacking basic residues by LC-ESI-MS/MS analysis of singly charged peptides

    Article • PROTEOMICS, May 2012, Wiley

    Dr Oliver Schilling

  121. NSP4, an elastase-related protease in human neutrophils with arginine specificity

    Article • Proceedings of the National Academy of Sciences, April 2012, Proceedings of the National Academy of Sciences

    Dr Oliver Schilling

  122. Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S

    Article • Journal of Proteome Research, December 2011, American Chemical Society (ACS)

    Dr Oliver Schilling

  123. Correction to Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S

    Article • Journal of Proteome Research, December 2011, American Chemical Society (ACS)

    Dr Oliver Schilling

  124. Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites

    Article • Biological Chemistry, November 2011, De Gruyter

    Dr Oliver Schilling

  125. Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts

    Article • Biological Chemistry, November 2011, De Gruyter

    Dr Oliver Schilling

  126. Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts

    Article • Biological Chemistry, September 2011, De Gruyter

    Dr Oliver Schilling

  127. Proteomic Analyses Reveal an Acidic Prime Side Specificity for the Astacin Metalloprotease Family Reflected by Physiological Substrates

    Article • Molecular & Cellular Proteomics, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  128. Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragmentsin Vivo

    Article • Journal of Biological Chemistry, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  129. Protease Specificity Profiling by Tandem Mass Spectrometry Using Proteome-Derived Peptide Libraries

    Article • January 2011, Springer Science + Business Media

    Dr Oliver Schilling

  130. Identification and Relative Quantification of Native and Proteolytically Generated Protein C-Termini from Complex Proteomes: C-Terminome Analysis

    Article • January 2011, Springer Science + Business Media

    Dr Oliver Schilling

  131. Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry

    Article • Nature Protocols, January 2011, Springer Science + Business Media

    Dr Oliver Schilling

  132. Biological role of matrix metalloproteinases: a critical balance

    Article • European Respiratory Journal, December 2010, European Respiratory Society (ERS)

    Dr Oliver Schilling

  133. Proteomic techniques and activity-based probes for the system-wide study of proteolysis

    Article • Biochimie, November 2010, Elsevier

    Dr Oliver Schilling

  134. Proteome-wide analysis of protein carboxy termini: C terminomics

    Article • Nature Methods, June 2010, Springer Science + Business Media

    Dr Oliver Schilling

  135. Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

    Article • Nature Biotechnology, March 2010, Springer Science + Business Media

    Dr Oliver Schilling

  136. Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

    Article • Nature Biotechnology, May 2008, Springer Science + Business Media

    Dr Oliver Schilling

  137. Protease subsite profiling with proteome-derived peptide libraries (PICS)

    Article • Protocol Exchange, May 2008, Springer Science + Business Media

    Dr Oliver Schilling

  138. Metal Requirements and Phosphodiesterase Activity of tRNase Z Enzymes †

    Article • Biochemistry, December 2007, American Chemical Society (ACS)

    Dr Oliver Schilling

  139. Proteomic discovery of protease substrates

    Article • Current Opinion in Chemical Biology, February 2007, Elsevier

    Dr Oliver Schilling

  140. The Crystal Structure of the Zinc Phosphodiesterase from Escherichia coli Provides Insight into Function and Cooperativity of tRNase Z-Family Proteins

    Article • Journal of Bacteriology, February 2006, ASM Journals

    Dr Oliver Schilling

  141. Exosite Modules Guide Substrate Recognition in the ZiPD/ElaC Protein Family

    Article • Journal of Biological Chemistry, February 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling

  142. Erratum to “Characterization of an Escherichia coli elaC deletion mutant” [Biochem. Biophys. Res. Commun. 320 (2004) 1365–1373]

    Article • Biochemical and Biophysical Research Communications, February 2005, Elsevier

    Dr Oliver Schilling

  143. The tRNase Z family of proteins: physiological functions, substrate specificity and structural properties

    Article • Biological Chemistry, January 2005, De Gruyter

    Dr Oliver Schilling

  144. Zinc- and iron-dependent cytosolic metallo-β-lactamase domain proteins exhibit similar zinc-binding affinities, independent of an atypical glutamate at the metal-binding site

    Article • Biochemical Journal, January 2005, Portland Press Ltd.

    Dr Oliver Schilling

  145. Functional diversity and metal selectivity of proteins sharing the metallo-β-lactamase fold

    Article • September 2004, Elsevier

    Dr Oliver Schilling

  146. Characterization of an Escherichia coli elaC deletion mutant

    Article • Biochemical and Biophysical Research Communications, August 2004, Elsevier

    Dr Oliver Schilling

  147. Identification of Metal Binding Residues for the Binuclear Zinc Phosphodiesterase Reveals Identical Coordination as Glyoxalase II

    Article • Biochemistry, July 2004, American Chemical Society (ACS)

    Dr Oliver Schilling

  148. The binding of iron and zinc to glyoxalase II occurs exclusively as di-metal centers and is unique within the metallo-β-lactamase family

    Article • JBIC Journal of Biological Inorganic Chemistry, April 2004, Springer Science + Business Media

    Dr Oliver Schilling

  149. Flexible Metal Binding of the Metallo-β-lactamase Domain:  Glyoxalase II Incorporates Iron, Manganese, and Zinc in Vivo †

    Article • Biochemistry, October 2003, American Chemical Society (ACS)

    Dr Oliver Schilling

  150. Activation Mechanism of Pro-astacin: Role of the Pro-peptide, Tryptic and Autoproteolytic Cleavage and Importance of Precise Amino-terminal Processing

    Article • Journal of Molecular Biology, November 2002, Elsevier

    Dr Oliver Schilling

  151. The GCM domain is a Zn-coordinating DNA-binding domain

    Article • FEBS Letters, September 2002, Wiley

    Dr Oliver Schilling

  152. ElaCEncodes a Novel Binuclear Zinc Phosphodiesterase

    Article • Journal of Biological Chemistry, May 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Schilling